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Image Challenge

The Hematologist Image Challenge column is a collection of interactive quizzes that test readers' knowledge of different hematologic or related conditions. See below for the complete Image Challenge archives while we develop an improved quiz experience for readers, coming this October.

The Dreaded Other Category: What's Different in This Differential?

September-October 2020 – Drs. Moe Takeda and Girish Venkataraman present the case of a persistent skin rash in a patient with a history of skin neoplasms.

Spots and Dots

July-August 2020 – Test your knowledge with an intriguing case from Drs. Pozdnyakova and Kim of a patient with end-stage renal disease status post renal transplant admitted to clinic with COVID-19.

Hyperbilirubinemia in Myelodysplastic Syndromes

May-June 2020 – Test your knowledge with an intriguing case from Drs. William Shomali, Jason Kurzer, and Peter Greenberg on the etiology of a patient's macrocytic anemia.

Bite Cells Abound

March-April 2020 – Test your knowledge with an intriguing case from Drs. Lindsey Shantzer and Kelly Davidson of a patient with anemia.

Fever in a Kidney Transplant Patient From Nigeria

January-February 2020 – Test your knowledge with an intriguing case from Drs. Karen Arispe and Alexandra Harrington of a patient with malaria.

A Skin Lesion in a Pediatric Patient: A Close Call

November-December 2019 – Take this Image Challenge by Drs. Gheorghe and Venkataraman to test the diagnosis of a pediatric patient with a skin lesion.

Spur Cell Anemia

September-October 2019 – Take this Image Challenge from Drs. Shomali, Fernandez-Pol, and Gotlib to test treatment and management of a middle-aged man with spur cell anemia.

A Woman With Thrombocytopenia Status Post-Partial Gastrectomy

July-August 2019 – Take this Image Challenge from Drs. Asif, Parker, and Aldarweesh to test the diagnosis of an elderly woman with thrombocytopenia status post-partial gastrectomy.

An Older Man With Cytopenias and Seemingly Normal-Looking Marrow

May-June 2019 – Take this image challenge from Drs. Kaumeyer, Arber, and Venkataraman featuring an older man with cytopenias after treatment of a previously diagnosed hematologic malignancy. Ancillary studies including molecular testing were needed to arrive at the diagnosis.

An Older Woman With Hemolytic Anemia

November-December 2018 – Take this Image Challenge by Drs. Shiraz Fiday and Geoffrey Wool to learn the diagnosis of a 73-year-old woman with hemolytic anemia.

A Transplant Patient With Visual Disturbance

September-October 2018 – Take this Image Challenge by Dr. Lyndsey Runaas and Dr. Steven Kroft to determine the diagnosis for a 34-year-old woman with new visual field defects.

Unusual Spindle Cell Lesion Involving Bone Marrow

July-August 2018 – In this Image Challenge, Dr. Venkataraman and Dr. Sir Philip look at a 65-year-old patient with syncope and mild hepatosplenomegaly whose blood count results prompted a bone marrow biopsy. Take a look at the bone marrow biopsy and blood smear to determine the diagnosis.

A Real Nose-Pincher

May-June 2018 – In this Image Challenge, Dr. Li and Dr. Kim present two peripheral blood smears and a bone marrow biopsy you can use to determine the cause of a patient's neutropenia.

A Man With Hyperleukocytosis and Massive Splenomegaly

March-April 2018 – Dr. Parker and Dr. Venkataraman present an image challenge that looks at the diagnosis of a man with hyperleukocytosis and massive splenomegaly.

A Man With Fevers, Headaches and Hemolytic Anemia

November-December 2017 – Take this image challenge to determine the diagnosis for a 65-year-old man who presented to clinic with one week of recurrent fevers, chills and severe headaches.

A Woman With Hypergammaglobulinemia and Diffuse Lymphadenopathy

September-October 2017 – Take the image challenge to determine the diagnosis for a woman with hypergammaglobulinemia and diffuse lymphadenopathy.

Not All Neutrophils Are Created Equal

July-August 2017 – Take the image challenge to determine what a 58-year-old man with a history of plasma cell myeloma was treated with.

Hyperleukocytosis and Abnormal Complete Blood Count

May-June 2017 – This Image Challenge looks at a 76-year-old man with a history of bladder cancer treated with two local resections and no chemotherapy or radiation, presenting to the hospital with hyperleukocytosis and an abnormal complete blood count.

Planting Evidence

March-April 2017 – Review the peripheral blood smear to determine the diagnosis of a 31-year-old man referred to hematology clinic for evaluation of long-standing thrombocytopenia.

When More (Oxygen) Is Not Better

March-April 2017 – Take the challenge to learn what test is most likely to yield the diagnosis for a case of a 58-year-old Asian woman with history of inclusion body myositis on high-dose corticosteroids and methotrexate, noted to be hypoxic.

Blasts of a Different Sort

January-February 2017 – Can you tell what the diagnosis is for a man with a history of recurrent necrotizing pancreatitis and end-stage renal disease on intermittent hemodialysis by looking at his bone marrow biopsy?

A Stimulating Case of Leukocytosis

November-December 2016 – Take the very first The Hematologist Image Challenge and try to figure out the diagnosis for a case of leukocytosis by looking at a peripheral blood smear.

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