...A history of venous thromboembolism (VTE) before pregnancy, hydroxyurea use before pregnancy, acute chest syndrome during pregnancy, and painful events needing acute care during pregnancy were all associated with VTE during pregnancy for women with sickle cell disease (SCD), according to a new...)

...Adverse pregnancy outcomes in thalassemic (Th3/+) mice, such as placenta enlargement and growth restriction, could be related to iron overload in a way not previously appreciated, according to research published in Blood . Though the findings need further exploration, they point to the need...)

...The American Medical Association (AMA) has adopted policies opposing the criminalization of pregnancy loss in the wake of the Dobbs decision that overturned Roe v. Wade. The policies were adopted by delegates to the Interim Meeting of the AMA House of Delegates. The policies are intended...)

... of California, San Francisco (UCSF) Center for Maternal-Fetal Precision Medicine, who helped lead the study. “No pregnancy has a guarantee of a good outcome, but what we were able to show is that offering [IUTs] earlier is ideal.” The findings offer what is possibly the most definitive data yet...)

...The risk of neonatal hypothyroidism in newborns from mothers exposed to computed tomography pulmonary angiography (CTPA) for suspected pulmonary embolism (PE) during pregnancy may be low. This is according to a prospective cohort study published in the Journal of Thrombosis and Haemostasis. 1...)

...There was no increased risk of severe bleeding during pregnancy among women with immune thrombocytopenia (ITP), according to a prospective, observational cohort study published in Blood. Pregnant women with ITP had similar rates of severe bleeding as women with ITP who were not pregnant, a useful...)

...Jean Marie Connors, MD Assistant Professor, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts This month, Jean Marie Connors, MD, discusses how long a 31-year-old patient should continue anticoagulation and the recommendations for pregnancy...)

...Venous thromboembolism (VTE) is associated with an increased prevalence of occult cancer. As pregnancy is also associated with an increased risk of VTE, it is unknown whether VTE during pregnancy or the postpartum period is similarly associated with an increased risk of a subsequent malignancy...)

... College of Medicine in Gainesville; co-director of the UF Obstetric Hematology Clinic   Because of physiologic changes during pregnancy, the risk of venous thromboembolism (VTE) is approximately five to 10 times higher than during non-pregnancy, and the postpartum risk is 15...)

...Gestational thrombocytopenia (defined as a platelet count <150,000/mm 3 during uncomplicated pregnancy) has been recognized for more than 25 years, but the course of platelet counts throughout pregnancy and the potential severity of gestational thrombocytopenia have not been well defined...)

...Women with atypical hemolytic uremic syndrome (aHUS) treated with eculizumab have similar pregnancy outcomes to women who were not treated with eculizumab, according to a review of post-marketing safety data presented at the 2019 Congress of the International Society on Thrombosis and Haemostasis...)

... or pregnancy history and risk of death among recipients. "While our findings will not particularly affect clinical care directly, as donor sex and parity is not considered when allocating blood units, our results should comfort clinicians that the current practice is safe," lead author Gustaf Edgren, MD...)

... explained, making family planning an important issue for these patients. However, management of CML around conception and pregnancy is not well-defined because "cases are rare and data are scarce." To clarify disease management in women who become pregnant, investigators conducted a multicenter...)

...In patients diagnosed with Hodgkin lymphoma (HL) during pregnancy, antenatal chemotherapy is associated with increased preterm contractions and lower birthweight for newborns, according to an analysis published in The Lancet Haematology . However, despite the increased risk of complications...)

...Preliminary findings from an observational multicenter study suggest that temporary off-label use of thrombopoietin receptor agonists (TPO-RAs) for the treatment of severe and/or refractory immune thrombocytopenia (ITP) during pregnancy is safe for the mother and neonate and may be effective when...)

...Prophylactic fresh frozen plasma (FFP) infusions may be necessary to replenish ADAMTS13 activity and maintain a successful pregnancy in expectant mothers with congenital thrombotic thrombocytopenic purpura (cTTP), according to a study published in the Journal of Thrombosis and Haemostasis...)

...Saskia Middeldorp, MD, PhD, and Wessel Ganzevoort, MD, PhD, discuss the diagnosis, treatment, and prevention of venous thromboembolism in pregnant women. This material is repurposed from "How I treat venous thromboembolism in pregnancy," published in the November 5, 2020, edition of Blood...)

...As female physicians tend to delay pregnancy until after their residencies, they are more susceptible to fertility issues. Nearly one in four female physicians who try to have a baby are diagnosed with infertility, according to a survey published in the Journal of Women’s Health in 2016...)

... outcomes. Given the lack of comprehensive data on pregnancy outcomes in these women, quantifying that risk and identifying groups of women at the highest risk for poor outcomes has been challenging. A new, first-of-its-kind meta-analysis reports that, when compared to healthy pregnant women, pregnant...)

...More patients with inherited bone marrow failure syndromes (IBMFS) are surviving to adulthood. As they do, they face barriers to pregnancy. It is still not clear how to counsel them on anticipated pregnancy outcomes, or optimal pregnancy management. In two Letters to the Editor published...)