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Yuet Kan

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Journal Articles
Journal: Blood
Blood (2006) 108 (11): 1594.
Published: 2006
...Lin Ye, PhD; Judy C. Chang, M.S; Kalee Chan, M.S; Ronghua Lu, Ph.D; Yuet Wai Kan, MD Several mouse models for sickle cell disease have been developed for the studies of the pathophysiology of sickle cell disease and the investigations of drug and gene therapies. In previous years, we have also...
Journal Articles
Journal: Blood
Blood (1998) 92 (8): 2924–2933.
Published: 1998
...Tohru Ikuta; Yuet Wai Kan; Paul S. Swerdlow; Douglas V. Faller; Susan P. Perrine The mechanisms by which pharmacologic agents stimulate γ-globin gene expression in β-globin disorders has not been fully established at the molecular level. In studies described here, nucleated erythroblasts were...
Journal Articles
Journal: Blood
Blood (1974) 43 (3): 411–415.
Published: 1974
...Yuet Wai Kan, M. B., B.S.; David G. Nathan, M.D.; Gabriel Cividalli, M.D.; Marie C. Crookston, B.Sc. Fetal red blood cells were concentrated from mixtures of maternal and fetal cells by differential agglutination with anti-i serum. This method will be useful for prenatal diagnosis...
Journal Articles
Journal: Blood
Blood (1974) 43 (1): 69–77.
Published: 1974
...Blanche P. Alter, M.D.; Yuet Wai Kan, M.B.; David G. Nathan, M.D. Cyanate inhibits hemoglobin synthesis in vitro. In vivo studies were performed to determine the effect of the drug on erythropoiesis. Adult female rats received daily intraperitoneal injections of 400 µmoles of cyanate, leading...
Journal Articles
Journal: Blood
Blood (1974) 43 (1): 57–68.
Published: 1974
...Blanche P. Alter, M.D.; Yuet Wai Kan, M.B.; David G. Nathan, M.D. Cyanate inhibits sickling and prolongs red cell survival in sickle cell anemia. However, cyanate markedly inhibits hemoglobin synthesis in vitro. Incorporation of radioactive amino acid into hemoglobin by human sickle reticulocytes...
Journal Articles
Journal: Blood
Blood (1972) 40 (5): 733–739.
Published: 1972
...Blanche P. Alter, M.D.; Yuet Wai Kan, M.B.; David G. Nathan, M.D. Cyanate prevents sickling in vitro and apparently prolongs the survival of 51 Cr-tagged sickle erythrocytes in vivo. Cautious interpretation is required because the effects of cyanate on 51 Cr binding to sickle and fetal hemoglobin...
Journal Articles
Journal: Blood
Blood (1974) 43 (5): 779–780.
Published: 1974
..., Charles A. 1-lartmann, Robert C. Heller, Paul Henderson, Edward S. Herzig, Geoffrey Holmsen, HoIm Hoyer, Leon W. Hsieh, Hsin-Soon Hughes, Walter L. Huguley, Charles M. Jam ieson, Graham A. Jepson, Joanne H. Jones, Oliver P. Kan, Yuet Wai Karnovsky, Manfred L. Krantz, Sanford Kretchmar, Arthur L. Krugman...
Journal Articles
Journal: Blood
Blood (1972) 39 (3): 451–452.
Published: 1972
... Crosby, William H. Ingram, Vernon Cudkowicz, Gustavo Iscove, Norman Blood, Vol. 39, No. 3 (March), 1972 451 452 ACKNOWLEDGMENT TO REVIEWERS Itano, Harvey A. Rapaport, Samuel I. Jamieson, Graham A. Rappazzo, Mary Jandi, James H. Rath, Charles E. Johnson, Alan J. Ratnoff, Oscar D. Kan, Yuet W. Rauscher, Jr...
Journal Articles
Journal: Blood
Blood (1989) 74 (2): 852–854.
Published: 1989
...- tute. Address reprint requests to Yuet Wai Kan. MD. Howard Hughes Medical Institute, U426, University of California. San Francisco, CA 94143. The publication costs ofthis article were defrayed in part by page charge payment. This article must therefore be hereby marked advertisement in accordance...
Journal Articles
Journal: Blood
Blood (1982) 60 (2): 509–512.
Published: 1982
... 509 Aipha-Thalassemia in Two Mediterranean Populations By Mario Pirastu, Kathleen Y. Lee, Andr#{233}eM. Dozy, Yuet Wai Kan, George Stamatoyannopoulos, Minas G. Hadjiminas, Zach Zachariades, Antonella AngiuS, Mario Furbetta, Cristina Rosatelli, and Antonio Cao We used restriction endonuclease analysis...
Journal Articles
Journal: Blood
Blood (1980) 55 (4): 706–708.
Published: 1980
... = 0.895, p less than 10(- 10)). Copyright © 1980 by The American Society of Hematology 1980 CONCISE REPORT 706 Blood, Vol. 55. No. 4 (April),1980 Alpha Globin Gene Number: Population and Restriction Endonuclease Studies By Gary Brittenham, Betsy Lozoff, John W. Harris, Yuet Wai Kan, Andr#{233}eM...
Journal Articles
Journal: Blood
Blood (1983) 62 (2): 341–345.
Published: 1983
... synthesis occurs. Copyright © 1983 by The American Society of Hematology 1983 -Tha1assemia in Sardinia Blood. Vol. 62, No. 2 (August). 1983: pp. 34 1-345 341 By Mario Pirastu, Renzo Galanello, Maria Antonietta Melis, Carlo Brancati, Antonio Tagarelli, Antonio Cao, and Yuet Wai Kan We have defined...
Journal Articles
Journal: Blood
Blood (1988) 71 (5): 1357–1360.
Published: 1988
... Multiple Mutations Occur By Shi-Ping Cal, Ji-Zeng Zhang, Dao-Hua Huang, Zhong-Xiang Wang, and Yuet Wai Kan We describe a simple approach for detecting -thaIasse- mia mutations in geographic areas such as southern China where multiple mutations are known to occur. Segments of the $-globin gene were...
Journal Articles
Journal: Blood
Blood (1998) 92 (7): 2535–2540.
Published: 1998
... 14233 18 Tournamille C Le Van Kim C Gane P Cartron JP Colin Y Molecular basis and PCR-DNA typing of the Fya/Fyb blood group polymorphism. Hum Genet 95 1995 407 19 Gossens M Yuet Kan Y DNA analysis in the diagnosis of hemoglobin disorders. Methods...
Journal Articles
Journal: Blood
Blood (1988) 71 (3): 766–770.
Published: 1988
... By Peter T. Curtin and Yuet Wai Kan We have previously described an English family with y#{244 thalassemia in which a large deletion stops 25 kilobases (kb) upstream from the fl-globin gene locus. and yet the fi-globin gene is inactive in vivo. Affected family members had a fi-thalassemia minor phenotype...
Journal Articles
Journal: Blood
Blood (1991) 77 (3): 644–648.
Published: 1991
... in altered glycosylation of this protein. Copyright © 1991 by The American Society of Hematology 1991 Molecular Characterization of Erythrocyte Glycophorin C Variants By Sharon Chang, Marion E. Reid, John Conboy, Yuet Wai Kan, and Narla Mohandas Human erythrocyte glycophorin C plays a functionally impor...
Journal Articles
Journal: Blood
Blood (1982) 59 (2): 370–376.
Published: 1982
...#{244}, Arnasalam Solai, Alejandro R. Herrera, Leigh Nicolaisen, Yuet Wai Kan, Wong Pui Wan, and Khalid Hasan The white blood cell DNA of 36 cord blood samples with Hb Bart s in the red blood cells was studied for a-globin gene deletions by hybridization of DNA fragments digested by the restriction...