...F. W. GUNZ © 1970 by American Society of Hematology, Inc. 1970 WILLIAM DAMESHEK, 1900-1969 W ILLIAM DAMESHEK died on October 6, 1969. He would have been 70 on May 22, 1970, and preparations were in train to celebrate this event worthily, when the blow fell. A week before his death he...

...Henry M. Stratton PWilliam Dameshek, A Personal Remembrance I FIRST MET Bill Dameshek over twenty-five years ago. I visited my old friend, Dr. Siegfried J. Thannhauser, in Boston, and discussed with him some of my thoughts about medical publishing. Because of my long-standing interest...

...James L. Tullis © 1970 by American Society of Hematology, Inc. 1970 William Dameshek, 1900-1969 P -i 1 H EMATOLOGISTS throughout the world were shocked to learn of the sudden death of William Dameshek on October 6, 1969. He died while undergoing open heart surgery in an attempt to repair...

...William H. Crosby © 1960 by American Society of Hematology, Inc. 1960 Short Biography of William Dameshek, M.D. BORN:May 22, 1900. M.D., Harvard Medical School, 1923. TITLES: Professcr of Medicine, Tufts University School of Medicine Senior Physician and Chief cf Helnatology, New England...

...CHARLES C. COLBY © 1960 by American Society of Hematology, Inc. 1960 585 Publications of Dr. William Dameshek-19221947 Coin piled by CHARLES C. COLBY* l)amcshek, \V.: Backache. Boston \l. &. S. J. 187: 830-834, 1922. The heart in hyperthyroidism. Boston M.& S.J. 190:487-497, 1924. -: Typhus...

...., Simess, J. F., and Congenital hypo- plastic anemia associated with miiultiple de- velopmmental defects (Fanconi syndrome); re- port of case. Blood 2:85-93, 1947. Publications of Dr. William Dameshek-1948--1959 Compiled by STANLEY D. TRUELSON, JR.* (References preceded by an asterisk were not verified...

...WILLIAM H. CROSBY © 1960 by American Society of Hematology, Inc. 1960 Dr. William Dameshek : A Biographical Comment I N 1955, while in Rome, I visited Professor Guiseppe Bastianelli, at that time94 years old. A physician, malariologist, hematologist and a medic l cosmo- politan if ever...

...HENRY M. STRATTON © 1960 by American Society of Hematology, Inc. 1960 To William Dameshek on His Sixtieth Birthday M Y DEAR Bill: It was seventeen years ago, in the office of our mutual friend, Dr. Siegfried Thannhauser, that we were first introduced. Al- though our meeting on that occasion...

...Barry S. Coller This year we celebrate Blood 's 70th year of publication. Created from the partnership of the book publisher Henry M. Stratton and the prominent hematologist Dr William Dameshek of Tufts School of Medicine, Blood has published many papers describing major advances in the science...

... findings was the modification of the World Health Organization classification and diagnostic algorithms for these diseases, which is still based on the original concept developed by William Dameshek in 1951 and keeps distinct entities under the umbrella of classical Philadelphia-negative MPNs. These MPNs...

...Ross L. Levine; D. Gary Gilliland In 1951 William Dameshek classified polycythemia vera (PV), essential thombocytosis (ET), and primary myelofibrosis (PMF) as pathogenetically related myeloproliferative disorders (MPD). Subsequent studies demonstrated that PV, ET, and PMF are clonal disorders...

... as a distinct clinical syndrome more than 6 decades ago and was classified as a myeloproliferative neoplasm (MPN) by William Dameshek in 1951, the molecular pathogenesis of ET remained unknown until 2005, when activating mutations in the JAK2 tyrosine kinase ( JAK2V617F ) were identified in a significant...

...Radek Skoda For many decades, myeloproliferative disorders (MPD) were largely neglected orphan diseases. The conceptual work of William Dameshek in 1951 provided the basis for understanding MPD as a continuum of related syndromes, possibly with a common pathogenetic cause. Recognition of the clonal...

... has accelerated in the past decade. The pathophysiological nature of this disease, as had been known in the past, was based largely on the intuitive and empiric notions of two leaders in hematology, William Dameshek and David Galton. Now the works of a new generation of leaders are providing us...

...WILLIAM H. CROSBY, MAJOR, MC, AUS; WILLIAM DAMESHEK, M.D. 1. Paroxysmal nocturnal hemoglobinuria is a hemolytic anemia of obscure origin, characterized by a defect of the erythrocytes which makes them susceptible to hemolysis by a normal plasma or serum factor. 2. The hemolytic reaction does...

...WILLIAM DAMESHEK © 1949 by American Society of Hematology, Inc. 1949 BLOOD The Journal of Hematology VOL. IV, NO. 5 MAY, 1949 PREFACE BLOOD CELLS AND THEIR REACTIONST WO YEARS AGO, a special issue of Blood, Morphologic Hematology, was published. At that time Blood was a bimonthly...

...WILLIAM DAMESHEK © 1947 by American Society of Hematology, Inc. 1947 EDITORIAL T HERE is much talk about the country regarding the prospects of founding a national society for the study of the blood. The great surge of interest in this field and the increasing numbers of workers who spend...

...William Dameshek © 1967 by American Society of Hematology, Inc. 1967 EDITORIAL Things Clinical Rumblings have been heard from time to time, perhaps increasingly so in recent months, indicating some dissatisfaction with what is said to be the rather heavy preponderance of ultrascientific...

...WILLIAM DAMESHEK EDITORIAL IS LEUKEMIA INCREASING?T HE article by Sacks and Seeman in this issue poses a question which has been troubling the interested observer for a number of years: Is leukemia increasing? We seem to see more and more cases of this disease all the time. Granted that this may...

...WILLIAM DAMESHEK © 1946 by American Society of Hematology, Inc. 1946 EDITORIAL THE TREATMENT OF POLYCYTHEMIA T HE treatment of polycythemia has passed through several successive stages since Osler first used benzol to reduce the excessive blood cell formation. Phenyihydrazine, a hemolytic...