Search Results for Robert Kyle

...Ola Landgren In the 1960s, Dr Jan Waldenström argued that patients who had monoclonal proteins without any symptoms or evidence of end-organ damage represented a benign monoclonal gammopathy. In 1978, Dr Robert Kyle introduced the concept of “monoclonal gammopathy of undetermined significance...

... Cell Dyscrasias: Patents & Royalties: Peer Review for Plasma Cell Dyscrasias (Editor: Robert Kyle); Glaxosmith Kline: Membership on an entity's Board of Directors or advisory committees; Takeda: Other: Multiple Myeloma Registry; AIM Specialty Health: Membership on an entity's Board of Directors...

...: Consultancy, Honoraria, Research Funding; Janssen: Honoraria, Research Funding. Thompson: UpToDate: Other: Consulting/royalties:Peer Review for Plasma Cell Dyscrasias (Editor: Robert Kyle); AIM Specialty Health: Membership on an entity's Board of Directors or advisory committees; VIA Oncology: Membership...

...Martha Lacy, MD; Angela Dispenzieri, MD; Suzanne R. Hayman, MD; Shaji Kumar, MD; Robert Kyle, MD; S. Vincent Rajkumar, MD; Brooks S. Edwards, MD; Richard J. Rodeheffer, MD; Frantz P. Robert, MD; Sudhir S. Kushwaha, MD; Alfedo L. Clavell, MD; Joseph A. Dearani, MD; Thoralf M. Sundt, MD; Richard C...

...David L Murray, MD, PhD; John R Mills, PhD; Jerry A. Katzmann, PhD; Robert Kyle, MD MACP; Vincent Rajkumar, MD; Angela Dispenzieri, MD; David R Barnidge, PhD Detection of an M-protein (monoclonal immunoglobulin) has been used to diagnose and monitor multiple myeloma (MM). As therapies for MM have...

...Jerry A. Katzmann, PhD; Angela Dispenzieri, MD; Robert Kyle, MD; Melissa R. Snyder, PhD; Mathew F. Plevak, BS; Dirk R. Larson, MS; Roshini S. Abraham, PhD; John A. Lust, MD,PhD; L. Joseph Melton, MD; S. Vincent Rajkumar, MD Due to the diagnostic sensitivity of serum free light chain quantitation...

...Natalia C. Gonzalez-Paz; Wee Joo Chng; Shaji Kumar; Tammy Price-Troska; Scott Van Wier; Gregory Ahmann; Kimberly Henderson; Morie Gertz; Robert Kyle; Philip Greipp; Rafael Fonseca Background: The p53 tumor suppressor gene has a common sequence polymorphism that results in either proline or arginine...

...Brian Van Ness, Ph.D.; Emily Blood, Ph.D.; Philip Greipp, M.D.; Neil Kay, M.D.; Vincent Rajkumar, M.D.; Robert Kyle, M.D.; Martin Oken, M.D.; Rafael Fonseca, M.D.; Fangyi Zhao, Ph.D. Although multiple myeloma is clinically defined as the accumulation of clonal, malignant plasma cells in the bone...

...Trey Carlton Mullikin, BS; S. Vincent Rajkumar, MD; Angela Dispenzieri, MD; Morie A Gertz, MD; Martha Q Lacy, MD; Francis Buadi, MD; Prashant Kapoor, MD; Jerry A. Katzmann, PhD; Dirk Larson; Robert Kyle, MD MACP; Shaji Kumar, MD Background: Patients with monoclonal gammopathies typically have...

...Francis Buadi, MB, ChB; Jerry A. Katzmann, Ph.D; Ruth M. Pfeiffer, Ph.D; Ann W. Hsing, Ph.D; Edward D. Yeboah, MD; Richard B. Biritwum, MD; Angela Dispenzieri, MD; Robert Kyle, MD; Vincent Rajkumar, MD; Ola Landgren, MD., PhD Introduction Diffuse or polyclonal hypergammaglobulinemia has been...

...Harris V.K. Naina, MBBS; Robert Kyle, MD; Thomas M. Habermann, MD; Samar Harris, MBBS; Fernando G. Cosio, MD; Mark D. Stegall, MD; Nelson Leung Background: Monoclonal gammopathy of undetermined significance (MGUS) is reported in 3 to 5 percent of population, with the prevalence increasing...

...; Taxiarchis Kourelis; S. Vincent Rajkumar; Robert Kyle; Angela Dispenzieri; Eli Muchtar Background: Iron deficiency (ID), a common cause of anemia, is often overlooked among patients with hematologic malignancies given alternative etiologies. Daratumumab is an anti-CD38 monoclonal antibody used...

...Harris V.K. Naina, MBBS; Robert Kyle, MD; Thomas M. Habermann, MD; Samar Harris, MBBS; Fernando G. Cosio, MD; Mark D. Stegall, MD; Leung Nelson, MD Background: Post-transplant lymphoproliferative disorder (PTLD) represents one of the most serious consequences of immunosuppression in patients...

...Joseph R. Mikhael, MD; Vivek Roy, M.D.; Paul G. Richardson, MD; Andrzej Jakubowiak, MD, PhD; Kristina Laumann; Betsy R. LaPlant; Angela Dispenzieri, MD; S. Vincent Rajkumar, MD; Rafael Fonseca, M.D.; Nelson Leung, MD; Francis Buadi, MD; P. Leif Bergsagel, MD; Robert Kyle, MD; MACP; Thomas E. Witzig...

..., MD, PhD; Yi Lin, MD, PhD; Robert Kyle, MD; MACP; Shaji K Kumar, MD Background The survival of patients with multiple myeloma (MM) has considerably improved during the last decade. MM at presentation is mostly limited to the bone marrow, with circulating plasma cells seen in a modest proportion...

...Angela Dispenzieri, MD; Amy K. Saenger, M.D.; Shaji K. Kumar, MD; Morie A. Gertz, M.D.; Martha Q Lacy, MD; Francis Buadi, MD; Suzanne R Hayman, MD; Nelson Leung, MD; Steven R Zeldenrust, MD, PhD; Arleigh McCurdy, MD; Robert Kyle, MD, MACP; David Dingli, M.D., Ph.D.; Prashant Kapoor, MD; Yi Lin...

...Shaji Kumar, MD; Angela Dispenzieri; Dirk Larson; Colin Colby; Robert Kyle; Morie Gertz; S.Vincent Rajkumar Background: Traditionally response to therapy in multiple myeloma (MM) is based on changes in the serum and urine monoclonal protein by immunoelectrophoresis. Immunofixation allows...

...Prashant Kapoor, MD; S. Vincent Rajkumar, MD; Angela Dispenzieri, MD; Martha Q. Lacy, MD; David Dingli, M.D., PhD.; Robert Kyle, M.D.; Morie A. Gertz, MD; Philip . R Greipp, MD; Shaji Kumar, MD; Sumithra J. Mandrekar, PhD Abstract 615 Background: Trials comparing efficacy of standard melphalan...

...Pierre Morel; Alain Duhamel; Paolo Gobbi; Meletios Dimopoulos; Madhav Dhodapkar; Jason McCoy; Enrique Ocio; Ramon Garcia-Sanz; Steven Treon; Veronique Leblond; Robert Kyle; Bart Barlogie; Giampaolo Merlini The outcome of patients (pts) with WM, a rare B-cell malignancy, varies widely...

...Robert Kyle, MD; Terry Therneau, PhD; Angela Dispenzieri, MD; Dirk Larson; Matthew Plevak; L.J. Melton, III, MD; S.V. Rajkumar, MD Chronic Idiopathic Bence Jones Proteinuria (first reported in 1982) is an asymptomatic plasma cell proliferative disorder that is associated with a risk of progression...