.... Manfred Karnovsky, Harvard Medical School, Boston; Cinephotomicrographic Studies of Phagocy- tosis, Dr. James Hirsch, Rockefeller Institute, New York City; Erythroclasia, Dr. James Jandl, Thorndike Memorial Laboratory, Boston. ...

...-Induced Bone Marrow Depres- sian. PAUL CARSON, University of Chicago Medical School: Metabolic Aspects of Drug- Induced Hemolysis. JAMES JANDL, Boston City Hospital: Drug-Induced Immunohemolytic Disease. N. RAPHAEL SHULMAN, National Institutes of Health: Drug-Induced Thrombocyto- penia. ...

...WILLIS R. KEENE, M.D.; JAMES H. JANDL, M.D.; Nancye M. Files Hemoglobin is cleared from plasma principally by the liver, moderately by the marrow, and relatively little by the spleen or other organs. Haptoglobin binding has no effect on this relative distribution, its only discernible role...

...JAMES H. JANDL, M.D. The normal survival of red cells requires maintained regulation of cell size and shape. This regulation is to a large extent dependent upon membrane permeability and the active transport of cations. Agents such as C' that affect permeability markedly by creating large holes...

...WILLIS R. KEENE, M.D.; JAMES H. JANDL, M.D. Quantitative studies were made in rats of the total reticuloendothelial cell content of bone marrow and of the ability of marrow to sequester antibody-treated red cells, immature red cells and carbon particles. Although normal marrow played a relatively...

...JAMES H. JANDL, M.D.; RICHARD L. SIMMONS, M.D.; WILLIAM B. CASTLE, M.D. Studies were made of the filterability of normal and abnormal red cells through an inert membrane-type (Millipore) filter having uniform non-branching capillary pores 5 µ in diameter. With this filter it was possible to remove...

...DAVID W. ALLEN; JAMES H. JANDL The kinetics of the intracellular iron were studied in an invitro system using reticulocyte-rich rabbit red cells incubated with Fe 59 -labeled plasma. The incubation was stopped at intervals of a few seconds to 70 minutes, and the cells were fractionated...

... Aspects of Drug- Induced Hemolysis. JAMES JANDL, Boston City Ho ital: Drug-Induced Immunohemolytic Disease. N. B..Iuii. za SHULMAN, National Inatitutes of Health: Drug-Induced Thrombocyto- penia. Dr. William Dameshek will open the discussion period. Tissue Culture Association Meeting The three-day...

... . The authors are indebted to our own mentors (John Adamson, Earl Davie, Clement Finch, Richard Cooper, Neil Abramson, Frank Bunn, James Jandl, and William Castle) for their example, inspiration, support, and friendship. References 1 Ishii T, Bruno E, Hoffman R, Xu M. Involvement of various...

... Medical Center Hosptial. We would like to express our sincere appreciation for the invaluable advice and criticisni of Richard Aster. M.D., and James Jandl, M.D., of the Thorndike Memorial Laboratory, Boston City Hospital, Boston. Massachusetts. REFERENCES 1. Rees, H. NI.. and Ecker, E. E.: An im- pro ed...

... of Phagocytic Activity, Dr. Manfred Karnovsky, Harvard Medical School, Boston; Cinephotomicrographic Studies of Phagocy- tosis, Dr. James Hirsch, Rockefeller Institute, New York City; Erythroclasia, Dr. James Jandl, Thorndike Memorial Laboratory, Boston. ...

... of macrophages in human atherosclerosis . Antioxid Redox Signal . 2021 ; 35 ( 12 ): 917 - 950 . 19. Bunn HF , Jandl JH . Exchange of heme among hemoglobins and between hemoglobin and albumin . J Biol Chem . 1968 ; 243 ( 3 ): 465 - 475 . 20. Nagy E , Eaton JW , Jeney V...

.... Harry S. Jacob, Sidney H. Ingbar and James H. Jandl (Introduced by Louis K. Diamond#{176 Thorndike Memorial Labo- ratory and Second and Fourth ( Harvard ) Medical Services, Bos- ton City Hospital and the Department of Medicine, Harvard Medi- cal School, Boston, Mass. 92. A RADIO-ENZYMATIC ASSAY...

... which is fast and efficient. In addition, a method of analysis of solubiized membrane components, i.e., polyacrylamide gel electro- phoresis, is described which is sensitive and reproducible. It has been suggested by Jandl that membrane protein may be important in the etiology of hereditary...

.... Manley OT, Marine D: The transplanta- tion of splenic tissue into the subcutaneous fascia of the abdomen in rabbits. J Exp Med 25:619- 628, 1917 19. Jacob HS, MacDonald RA, Jandl JH: Regulation of spleen growth and sequestering function. J Clin Invest 42:1476-1490, 1963 eration and transplantation...

...: 715, 1954. 14. Herbert, V.: Experimental nutritional folate deficiency in man. Tm. A. Am. Physicians 25:307, 1962. 15. jandl, J. H., and Greenberg, M. S.: Bone marrow failure due to relative nutritional deficiency in Cooley s hemolytic anemia. New England J. Med. 260:461, 1959. 16. Herbert, V...

... Medical School: Drug-Induced Bone Marrow Depres- sian. PAUL CARSON, University of Chicago Medical School: Metabolic Aspects of Drug- Induced Hemolysis. JAMES JANDL, Boston City Hospital: Drug-Induced Immunohemolytic Disease. N. RAPHAEL SHULMAN, National Institutes of Health: Drug-Induced Thrombocyto...

... LCOLM HARGRAVES, Rochester, Minn. WILLIAM HARRINGTON, St. Louis, Mo. J. W. hliRms, (leveland, 0. JAMES II. JANDL, Boston, Mass. WALLY JENSEN, Pittsburgh, Pa. GEORGE B. JERZY GLASS, New York, N. Y. A. RIcHARDSON JONES, Boston, Mass. F. L. J. JORDAN, Utnecht, Holland AARON M. JosEpHsoN, Chicago, Ill...

... studies on human semi-hemiglobin. Biochim. Biophys. Acta 133 :557, 1967. 30. Perutz, M. F., and Lehmann, H.: Molecular pathology of human haemo- globin. Nature (London) 219:902, 1968. 31. Bunn, H. F., and Jandl, J. H.: Ex- change of heme among hemoglobins and between hemoglobin and albumin. J. Biol. Chem...

..., E., Rubin, M. I., and Ingas- ser, L. M.: Studies in erythroblastosis fetalis. J. Lab. & din. Med. 32:1339, 1947. 5. Jandl, J. H., and Castle, W. B.: Agglu- tination of sensitized red cells by large anisometric molecules. J. Lab. & Clin. Mcd. 47:669, 1956. 8. Ham, T. H.; A Syllabus of Laboratory...