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Aaron Marcus

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Journal Articles
Journal: Blood
Blood (1971) 37 (6): 675–683.
Published: 1971
...PETER ELSBACH, M.D.; PENELOPE PETTIS, B.S.; AARON MARCUS, M.D. Human platelets incubated with 32 P lysolecithin convert this compound to platelet lecithin and the water-soluble product glycerylphosphorylcholine. Lecithin synthesis from lysolecithin by intact platelets has a pH optimum of 9, whereas...
Journal Articles
Journal: Blood
Blood (1970) 36 (4): 546–548.
Published: 1970
... 1:30 to 4:30 P.M. Simultaneous sessions will be held on the following subjects: ERYvins0P0JESIS: Chairmen, Dr. Denmar& Hammond and Dr. Clifford W. Gurney NUTRITIONAL AN nAS: Chairmen, Dr. F. A. Klipstein and Dr. Bernard Cooper PLATELETS: Chairmen, Dr. Aaron Marcus and Dr. Theodore Spaet...
Journal Articles
Journal: Blood
Blood (1970) 36 (3): 417–419.
Published: 1970
... Monday, December 7, and Tuesday, December 8 1:30 to 4:30 P.M. Simultaneous sessions will be held on the following subjects: ERYmnoPolEsIs : Chairmen, Dr. Denman Hammond and Dr. Clifford W. Gurney NUTRITIONAL ANEMIAS: Chairmen, Dr. F. A. Klipstein and Dr. Bernard Cooper PLATELETS: Chairmen, Dr. Aaron...
Journal Articles
Journal: Blood
Blood (2017) 129 (18): 2537–2546.
Published: 2017
...Bethany L. Walton; Marcus Lehmann; Tyler Skorczewski; Lori A. Holle; Joan D. Beckman; Jeremy A. Cribb; Micah J. Mooberry; Adam R. Wufsus; Brian C. Cooley; Jonathan W. Homeister; Rafal Pawlinski; Michael R. Falvo; Nigel S. Key; Aaron L. Fogelson; Keith B. Neeves; Alisa S. Wolberg Red blood cells...
Includes: Supplemental data
Journal Articles
Journal: Blood
Blood (1970) 36 (5): 684–688.
Published: 1970
... AND LEUKEMOGENESIS. Robert Gallo, Na- tional Cancer Institute C. PANEL DISCUSSION SUNDAY, DECEMBER 6, 1:30 p.m. to 5:00 p.m. MEETING OF SUBCOMMITTEE ON HEMOSTASIS Chairman: Yale Nemerson THE CONTACT SYSTEM. Hynzie Nossel, Columbia University, New York THE ROLE OF PHOSPHOLIPIDS IN BLOOD COAGULATION. Aaron Marcus...
Journal Articles
Jie Huang, Maria Sabater-Lleal, Folkert W. Asselbergs, David Tregouet, So-Youn Shin, Jingzhong Ding, Jens Baumert, Tiphaine Oudot-Mellakh, Lasse Folkersen, Andrew D. Johnson, Nicholas L. Smith, Scott M. Williams, Mohammad A. Ikram, Marcus E. Kleber, Diane M. Becker, Vinh Truong, Josyf C. Mychaleckyj, Weihong Tang, Qiong Yang, Bengt Sennblad, Jason H. Moore, Frances M. K. Williams, Abbas Dehghan, Günther Silbernagel, Elisabeth M. C. Schrijvers, Shelly Smith, Mahir Karakas, Geoffrey H. Tofler, Angela Silveira, Gerjan J. Navis, Kurt Lohman, Ming-Huei Chen, Annette Peters, Anuj Goel, Jemma C. Hopewell, John C. Chambers, Danish Saleheen, Per Lundmark, Bruce M. Psaty, Rona J. Strawbridge, Bernhard O. Boehm, Angela M. Carter, Christa Meisinger, John F. Peden, Joshua C. Bis, Barbara McKnight, John Öhrvik, Kent Taylor, Maria Grazia Franzosi, Udo Seedorf, Rory Collins, Anders Franco-Cereceda, Ann-Christine Syvänen, Alison H. Goodall, Lisa R. Yanek, Mary Cushman, Martina Müller-Nurasyid, Aaron R. Folsom, Saonli Basu, Nena Matijevic, Wiek H. van Gilst, Jaspal S. Kooner, Albert Hofman, John Danesh, Robert Clarke, James B. Meigs, DIAGRAM Consortium, Sekar Kathiresan, Muredach P. Reilly, CARDIoGRAM Consortium, Norman Klopp, Tamara B. Harris, Bernhard R. Winkelmann, Peter J. Grant, Hans L. Hillege, Hugh Watkins, C4D Consortium, Timothy D. Spector, Lewis C. Becker, Russell P. Tracy, Winfried März, Andre G. Uitterlinden, Per Eriksson, Francois Cambien, CARDIOGENICS Consortium, Pierre-Emmanuel Morange, Wolfgang Koenig, Nicole Soranzo, Pim van der Harst, Yongmei Liu, Christopher J. O'Donnell, Anders Hamsten
Journal: Blood
Blood (2012) 120 (24): 4873–4881.
Published: 2012
...-Christine Syvänen; Alison H. Goodall; Lisa R. Yanek; Mary Cushman; Martina Müller-Nurasyid; Aaron R. Folsom; Saonli Basu; Nena Matijevic; Wiek H. van Gilst; Jaspal S. Kooner; Albert Hofman; John Danesh; Robert Clarke; James B. Meigs; DIAGRAM Consortium; Sekar Kathiresan; Muredach P. Reilly; CARDIoGRAM...
Includes: Supplemental data
Journal Articles
Journal: Blood
Blood (2012) 120 (21): 3397.
Published: 2012
...Aaron J Marcus, MD; Joan HF Drosopoulos, PhD; Kim E Olson, MD; Ranjini Anand, MS; Dana Leifer, MD; Jorge R Kizer, MD Abstract 3397 Background: In the US, 795,000 patients are diagnosed with stroke annually. Of the 90% of strokes that are ischemic, a substantial number are of unknown etiology...
Journal Articles
Journal: Blood
Blood (2012) 119 (15): 3378–3379.
Published: 2012
...Aaron J. Marcus © 2012 by The American Society of Hematology 2012 In a highly interesting, intricate, and novel paper in this issue of Blood , Fung and colleagues have extended their previous pioneering studies and now reveal that molecules such as ATP can promote platelet activation...
Journal Articles
Journal: Blood
Blood (2011) 118 (21): 1285.
Published: 2011
...Roksana Moraghebi; Roger Emanuel Rönn; Claudia Stolz; Patricia Chaves Guerrero; Aaron Parker; Andreas Herbst; Marcus Larsson; Ewa Sitnicka; Inder Verma; Niels-Bjarne Woods Abstract 1285 Identifying the key regulatory genes that direct human ES/iPS cell differentiation to certain lineages...
Journal Articles
Journal: Blood
Blood (2010) 116 (21): 2110.
Published: 2010
...Kim Olson, MD; Aaron j Marcus, MD Abstract 2110 HUVECs, neutrophils, monocyte/macrophages and T cell subsets all express ectonucleoside triphosphate diphosphohydrolase 1 (CD39) on the cell surface. In addition, they all express both P2X and P2Y receptors and dose dependently respond to ATP. ATP...
Journal Articles
Journal: Blood
Blood (2008) 112 (11): 3925.
Published: 2008
...Kim E Olson, MD; Joan HF Drosopoulos, PhD; Ashley E Olson, BS; Marinus Johan Broekman, PhD; Aaron J Marcus, MD We have previously shown that CD39 undergoes limited cleavage and that inhibition of proteolysis results in a decrease in ATPase activity. The reduction in enzymatic activity correlated...
Journal Articles
Journal: Blood
Blood (2008) 112 (11): 3817.
Published: 2008
...Aaron J. Marcus, MD; Marinus Johan Broekman, PhD; Joan HF Drosopoulos, PhD; Kim E. Olson, MD; Dianne Pulte, MD; Jorge R. Kizer In the US, 780,000 people are diagnosed with stroke annually, of which 180,000 are recurrent. Nearly 90% of strokes are ischemic and 10% hemorrhagic. Roughly 30...
Journal Articles
Journal: Blood
Blood (2007) 110 (11): 3634.
Published: 2007
...Kim E. Olson, MD; Marinus Johan Broekman, PhD; Ashley E. Olson, BS; Dianne Pulte, MD; Aaron J. Marcus, MD Brief trypsin exposure increases apyrase activity in hCD39 expressing cells, as previously reported ( Schulte am Esch et al, Biochemistry 38 : 2248 , 1999 ). Since regulated proteolytic...
Journal Articles
Journal: Blood
Blood (2006) 108 (11): 1733.
Published: 2006
...Dianne Pulte, MD; Marinus Johan Broekman, PhD; Joan Drosopoulos, PhD; Kim E. Olson, MD; Naziba Islam, MS; Aaron J. Marcus, MD CD39/NTPDase-1 is an ecto-ATP/ADPase expressed on leukocytes and endothelial cells. CD39 is the main control system for blood fluidity. CD39 on lymphocytes was first...
Journal Articles
Journal: Blood
Blood (2005) 106 (11): 3088.
Published: 2005
...Kim E. Olson, MD; Dianne Pulte, MD; Marinus Johan Broekman, PhD; Ashley E. Olson, BS; Joan Drosopoulos, PhD; Naziba Islam, MS; Elgilda Musi, BS, MA; Aaron J. Marcus, MD Blood-borne cellular elements expressing ectonucleotidase activity have been shown to regulate platelet activation and recruitment...
Journal Articles
Journal: Blood
Blood (2005) 106 (11): 4974.
Published: 2005
...E. Dianne Pulte, MD; Kim Olson, MD; Naziba Islam, MS; M. Johan Broekman, PhD; Harold Ballard, MD; Aaron J. Marcus, MD Chronic lymphocytic leukemia (CLL) is characterized by accumulation of large numbers of mature lymphocytes. However, thrombotic events in CLL are relatively rare. CD39, the main...
Journal Articles
Journal: Blood
Blood (2004) 104 (11): 1846.
Published: 2004
...Kim E. Olson, MD; Joan H.F. Drosopoulos, PhD; Marinus J. Broekman, PhD; Naziba Islam, MS; Dianne Pulte, MD; Aaron J. Marcus, MD To study thrombogenesis in wild-type and transgenic mice we engineered a recombinant, soluble form of murine ENTPDase1/CD39 for use as a therapeutic agent. ENTPDase1...
Journal Articles
Journal: Blood
Blood (2004) 104 (11): 1869.
Published: 2004
...Takuji Machida, MS; Paul M. Heerdt, MD, PhD; Alicia C. Reid, BS; Ulrich Schaefer, MD; Randi B. Silver, PhD; Marinus Johan Broekman, PhD; Aaron J. Marcus, MD; Roberto Levi, MD, DSc ATP co-released with norepinephrine (NE) from cardiac sympathetic nerve terminals increases NE exocytosis via...
Journal Articles
Journal: Blood
Blood (2004) 104 (11): 530.
Published: 2004
...Soon S. Jeong, PhD; Marinus J. Broekman, PhD; Timothy A. Mitsky, BSc; Ridong Chen, PhD; Aaron J. Marcus, MD Recent emphasis has been on ADP as a mediator of thrombotic events characterized by excessive platelet reactivity. In contrast, neither ATP nor AMP induces platelet activation. Thus...
Journal Articles
Journal: Blood
Blood (2002) 99 (11): 3978–3984.
Published: 2002
...Juana Vallés; M. Teresa Santos; Justo Aznar; Marcial Martı́nez; Antonio Moscardó; Marta Piñón; M. Johan Broekman; Aaron J. Marcus Activated platelets release biologically active compounds, which then recruit additional platelets into an evolving thrombus. We studied activation of α IIb β 3...