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leukemia

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Journal Articles
Clinical Trials & Observations
Journal: Blood
Blood (2015) 126 (17): 2062–2069.
Published: 2015
...; Sebastian Giebel; Emmanuelle Polge; Jordi Esteve; Arnon Nagler; Mohamad Mohty To analyze the influence of distinct combinations of molecular aberrations on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) for cytogenetically normal acute myeloid leukemia (CN-AML), a retrospective...
Includes: Supplemental data
Journal Articles
Clinical Trials & Observations
Journal: Blood
Blood (2014) 124 (26): 3870–3879.
Published: 2014
...; Katarzyna Domanska-Czyz; Rainer Fietkau; Heinz-August Horst; Harald Rieder; Stefan Schwartz; Thomas Burmeister; Nicola Gökbuget This largest prospective multicenter trial for adult patients with Burkitt lymphoma/leukemia aimed to prove the efficacy and feasibility of short-intensive chemotherapy combined...
Includes: Supplemental data
Journal Articles
Journal: Blood
Blood (2019) 133 (25): 2651–2663.
Published: 2019
...Emanuela M. Ghia; Laura Z. Rassenti; Donna S. Neuberg; Alejandro Blanco; Fouad Yousif; Erin N. Smith; John D. McPherson; Thomas J. Hudson; the HALT Pan-Leukemia Gene Panel Consortium; Olivier Harismendy; Kelly A. Frazer; Thomas J. Kipps Targeted sequencing of 103 leukemia-associated genes...
Includes: Supplemental data
Journal Articles
Journal: Blood
Blood (2010) 116 (18): 3564–3571.
Published: 2010
...; Wilhelm Schmitz; Peter Schlenke; Michael McClelland; Wolfgang E. Berdel; Martin Dugas; Hubert Serve; on behalf of the Study Alliance Leukemia Acute myeloid leukemia (AML) is commonly associated with alterations in transcription factors because of altered expression or gene mutations. These changes might...
Includes: Supplemental data
Journal Articles
Journal Articles
Journal: Blood
Blood (2006) 108 (11): 263.
Published: 2006
...Cesare Guglielmi; Stefania Bergantini; Simona Iacobelli; Anja van Biezen; Eduardo Olavarria; Alois Gratwohl; Antonius V.M.B. Schattenberg; Leo F. Verdonck; Dietger W. Niederwieser; T.M. de Witte; for the Chronic Leukemia Working Party of the EBMT Donor lymphocyte infusions (DLI) have radically...
Journal Articles
Clinical Trials & Observations
Journal: Blood
Blood (2003) 102 (8): 3043–3051.
Published: 2003
...Norbert C. Gorin; Myriam Labopin; Vanderson Rocha; William Arcese; Meral Beksac; Eliane Gluckman; Olle Ringden; Tapani Ruutu; Josy Reiffers; Giuseppe Bandini; Michele Falda; Panagiotis Zikos; Roelf Willemze; Francesco Frassoni; for the Acute Leukemia Working Party (ALWP) of the European Cooperative...
Journal Articles
Clinical Trials & Observations
Journal: Blood
Blood (2003) 101 (4): 1611–1619.
Published: 2003
... complications, we analyzed, in a retrospective, multicenter study, 387 children who underwent autologous hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML) in first complete remission (CR). Median follow-up time from transplantation was 60 months. Transplantation of bone marrow...
Journal Articles
Clinical Trials & Observations
Journal: Blood
Blood (2002) 99 (8): 2734–2739.
Published: 2002
...Michel Duval; Stefan Suciu; Alina Ferster; Xavier Rialland; Brigitte Nelken; Patrick Lutz; Yves Benoit; Alain Robert; Anne-Marie Manel; Etienne Vilmer; Jacques Otten; Noël Philippe Asparaginase is an enzyme used in the treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma...
Journal Articles
Journal: Blood
Blood (1998) 92 (2): 596–599.
Published: 1998
...M.C. Bene; M. Bernier; R.O. Casasnovas; G. Castoldi; W. Knapp; F. Lanza; W.D. Ludwig; E. Matutes; A. Orfao; C. Sperling; M.B. van't Veer We document findings on c-kit (CD117) expression in 1,937 pediatric and adult de novo acute leukemia cases, diagnosed in five single European centers. All cases...
Journal Articles
Journal: Blood
Blood (2018) 132 (Supplement 1): 485.
Published: 2018
... : Haploidentical (Haplo) stem cell transplantation (SCT) provide a curative option for nearly all Acute Myeloid Leukemia (AML) patients lacking an HLA matched donor. However, outcomes following Haplo-SCT vary and are dependent on a number of individual features. Integrative prognostic models for decision support...
Journal Articles
Journal: Blood
Blood (2018) 132 (Supplement 1): 1360.
Published: 2018
... (H3K9me2), as well as several non-histone lysine sites. Recently, pharmacological and genetic targeting of the G9a was shown to be efficient in slowing down acute myeloid leukemia (AML) cell proliferation in a mouse model and human AML cell lines thus making this HMTase potential target for epigenetic...
Journal Articles
Journal: Blood
Blood (2016) 128 (22): 281.
Published: 2016
...; Christopher L Nobles, PhD; Frederic D Bushman, PhD; Elena Orlando, PhD; Stephan A. Grupp, MD PhD; Carl H June, MD; Jan Joseph Melenhorst, PhD T cells bearing a second-generation anti-CD19 chimeric antigen receptor (CAR) induce complete remission in >90% of patients with acute lymphoblastic leukemia (ALL...
Journal Articles
Journal Articles
Journal: Blood
Blood (2016) 128 (22): 2912.
Published: 2016
... significance of leukemia stem cells (LSCs) in acute myeloid leukemia (AML). However, the identification of LSCs in acute lymphocytic leukemia (ALL) has proved challenging, as transplantation studies in immunocompromised mice have yielded conflicting results. The distinction between Philadelphia chromosome...
Journal Articles
Journal Articles
Journal: Blood
Blood (2014) 124 (21): 950.
Published: 2014
... E. Bueso-Ramos, MD PhD; Jorge E. Cortes, MD; Michael Andreeff, MD PhD Background : The bone marrow (BM) niche protects Acute Myeloid Leukemia (AML) cells from chemotherapy. BM homing of AML cells is dependent on CXCR4 and its ligand CXCL12, and high levels of CXCR4 expression correlate with poor...
Journal Articles
Journal Articles
Journal: Blood
Blood (2014) 124 (21): 967.
Published: 2014
...Jordan Jacobelli, PhD; Eric Wigton; Scott B Thompson Background: Leukemia affects approximately 45,000 people each year in the USA with more than 20,000 fatalities. Many leukemia patients experience initial remission but often relapse, with the relapsing leukemia affecting organs...
Journal Articles
Journal: Blood
Blood (2019) 134 (24): 2171–2182.
Published: 2019
...Sara González-García; Marta Mosquera; Patricia Fuentes; Tiziana Palumbo; Adela Escudero; Antonio Pérez-Martínez; Manuel Ramírez; Anne E. Corcoran; Maria L. Toribio T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy resulting from the dysregulation of signaling...
Includes: Supplemental data