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©2023 by the American Society of Hematology

ISSN 1520-4391 (print), ISSN 1520–4383 (online)

Hematology, the ASH Education Program, is published annually by the American Society of Hematology (ASH) in one volume per year.

All business correspondence and purchase and reprint requests should be addressed to the American Society of Hematology, 2021 L Street, NW, Suite 900, Washington, DC 20036, USA; phone: 202-776-0544; fax: 202-776-0545; e-mail:

© 2023 by The American Society of Hematology. All rights reserved. Copyright is not claimed in any works of the United States Government. Except as expressly permitted in this statement, no part of this publication may be used (as here in after defined) in any form or by any means now or hereafter known, electronic or mechanical, without permission in writing from the Publisher, The American Society of Hematology. For purposes of this notice, the term “use” includes but is not limited to reproduction, photocopying, storage in a retrieval system, translation, and transmittal. The Publisher hereby consents to the use of this publication or any part hereof for any noncommercial educational purpose within the health field such as classroom instruction and clinical and residency training. This publication or any part thereof may be used for educational purposes at conferences, continuing education courses, and other educational activity, provided no fee or other compensation is charged therefor. All materials so used must acknowledge the Publisher’s copyright therein as “© 2023 by The American Society of Hematology.” When requesting the Publisher’s permission to use this publication or any part thereof, please contact the Copyright Clearance Center at 222 Rosewood Drive, Danvers, MA 01923, USA; phone: 978-750-8400; fax: 978-750-4470; or The American Society of Hematology Publications Department at 2021 L Street, NW, Suite 900, Washington, DC 20036, USA; phone: 202-776-0544; fax: 202-776-0545.

Article Citations: Cite articles in this volume by listing Author(s), Title, Hematology Am Soc Hematology Edu Program. 2023;2023.: beginning page number- ending page number.

Hematology Rights and Permission 
To request permission to reprint or reuse Hematology articles, figures, or tables, please visit the Hematology page at the Copyright Clearance Center

The publisher disclaims responsibility for opinions expressed by the authors.

Cover: Illustration of activated platelets. Source: Kateryna Kon/Science Photo Library.

This activity is supported by educational grants from AstraZeneca;Incyte Corp.; Jazz Pharmaceuticals,Inc.; Merck Sharp & Dohme Corp.; and Novartis Pharmaceuticals Corp.

Editors Message


Committee on Educational Affairs

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