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Journal Articles

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions

Emilie Montenont, Seema Bhatlekar, Shancy Jacob, Yasuhiro Kosaka, Bhanu K. Manne, Olivia Lee, Ivan Parra-Izquierdo, Emilia Tugolukova, Neal D. Tolley, Matthew T. Rondina, Paul F. Bray, Jesse W. Rowley

Blood Adv (2021) 5 (9): 2362–2374.

https://doi.org/10.1182/bloodadvances.2020004112

Published: 2021

Includes: Supplemental data

Journal Articles

Transfer to the clinic: refining forward programming of hPSCs to megakaryocytes for platelet production in bioreactors

Amanda L. Evans, Amanda Dalby, Holly R. Foster, Daniel Howard, Amie K. Waller, Momal Taimoor, Moyra Lawrence, Souradip Mookerjee, Marcus Lehmann, Annie Burton, Jorge Valdez, Jonathan Thon, Joseph Italiano, Thomas Moreau, Cedric Ghevaert

Blood Adv (2021) 5 (7): 1977–1990.

https://doi.org/10.1182/bloodadvances.2020003236

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Sonia Poirault-Chassac, Valérie Nivet-Antoine, Amandine Houvert, Alexandre Kauskot, Evelyne Lauret, René Lai-Kuen, Isabelle Dusanter-Fourt, Dominique Baruch

Blood Adv (2021) 5 (6): 1706–1718.

https://doi.org/10.1182/bloodadvances.2020002847

Published: 2021

Includes: Supplemental data

Journal Articles

Low-dose decitabine for refractory prolonged isolated thrombocytopenia after HCT: a randomized multicenter trial

Blood Adv (2021) 5 (5): 1250–1258.

https://doi.org/10.1182/bloodadvances.2020002790

Published: 2021

Includes: Supplemental data

Journal Articles

Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation

Michelle C. Krutein, Matthew R. Hart, Donovan J. Anderson, Jasmin Jeffery, Andriana G. Kotini, Jin Dai, Sylvia Chien, Michaela DelPriore, Sara Borst, Jean Ann Maguire, Deborah L. French, Paul Gadue, Eirini P. Papapetrou, Siobán B. Keel, Pamela S. Becker, Marshall S. Horwitz

Blood Adv (2021) 5 (3): 687–699.

https://doi.org/10.1182/bloodadvances.2020002709

Published: 2021

Includes: Supplemental data

Journal Articles

JAK2 S523L, a novel gain-of-function mutation in a critical autoregulatory residue in JAK2 V617F − MPNs

Friederike Pastore, Aishwarya Krishnan, Henrik M. Hammarén, Olli Silvennoinen, Benedict Yan, Ross L. Levine

Blood Adv (2020) 4 (18): 4554–4559.

https://doi.org/10.1182/bloodadvances.2019001283

Published: 2020

Includes: Supplemental data

Journal Articles

Artificial intelligence–based morphological fingerprinting of megakaryocytes: a new tool for assessing disease in MPN patients

Korsuk Sirinukunwattana, Alan Aberdeen, Helen Theissen, Nikolaos Sousos, Bethan Psaila, Adam J. Mead, Gareth D. H. Turner, Gabrielle Rees, Jens Rittscher, Daniel Royston

Blood Adv (2020) 4 (14): 3284–3294.

https://doi.org/10.1182/bloodadvances.2020002230

Published: 2020

Includes: Supplemental data

Journal Articles

EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis

Ayaka Yamaoka, Mikiko Suzuki, Saori Katayama, Daiki Orihara, James Douglas Engel, Masayuki Yamamoto

Blood Adv (2020) 4 (8): 1722–1736.

https://doi.org/10.1182/bloodadvances.2019000978

Published: 2020

Includes: Supplemental data

Journal Articles

Human megakaryocytic microparticles induce de novo platelet biogenesis in a wild-type murine model

Christian Escobar, Chen-Yuan Kao, Samik Das, Eleftherios T. Papoutsakis

Blood Adv (2020) 4 (5): 804–814.

https://doi.org/10.1182/bloodadvances.2019000753

Published: 2020

Includes: Supplemental data

Journal Articles

IκB kinase 2 is not essential for platelet activation

Manuel Salzmann, Sonja Bleichert, Bernhard Moser, Marion Mussbacher, Mildred Haase, Bastian Hoesel, Waltraud C. Schrottmaier, Julia B. Kral-Pointner, Makoto Itakura, Katy Schmidt, Alice Assinger, Johannes A. Schmid

Blood Adv (2020) 4 (4): 638–643.

https://doi.org/10.1182/bloodadvances.2019001044

Published: 2020

Includes: Supplemental data

Journal Articles

Imetelstat inhibits growth of megakaryocyte colony-forming units from patients with essential thrombocythemia

Gabriela M. Baerlocher, Monika Haubitz, Thomas R. Braschler, Claudio Brunold, Bart Burington, Elisabeth Oppliger Leibundgut, Ning Go

Blood Adv (2019) 3 (22): 3724–3728.

https://doi.org/10.1182/bloodadvances.2019000167

Published: 2019

Journal Articles

Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Gerbrig Berger, Mylene Gerritsen, Guoqiang Yi, Theresia N. Koorenhof-Scheele, Leonie I. Kroeze, Marian Stevens-Kroef, Kenichi Yoshida, Yuichi Shiraishi, Eva van den Berg, Hein Schepers, Geert Huls, André B. Mulder, Seishi Ogawa, Joost H. A. Martens, Joop H. Jansen, Edo Vellenga

Blood Adv (2019) 3 (20): 3111–3122.

https://doi.org/10.1182/bloodadvances.2019000518

Published: 2019

Includes: Supplemental data

Journal Articles

Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets

Elisabeth M. Battinelli, Jonathan N. Thon, Ross Okazaki, Christian G. Peters, Prakrith Vijey, Adrian R. Wilkie, Leila J. Noetzli, Robert Flaumenhaft, Joseph E. Italiano, Jr

Blood Adv (2019) 3 (20): 3092–3098.

https://doi.org/10.1182/bloodadvances.2018020834

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials

Yueh-Chwen Hsu, Tsung-Chih Chen, Chien-Chin Lin, Chang-Tsu Yuan, Chia-Lang Hsu, Hsin-An Hou, Chein-Jun Kao, Po-Han Chuang, Yu-Ren Chen, Wen-Chien Chou, Hwei-Fang Tien

Blood Adv (2019) 3 (15): 2355–2367.

https://doi.org/10.1182/bloodadvances.2019000391

Published: 2019

Includes: Supplemental data

Journal Articles

Dysregulated megakaryocyte distribution associated with nestin + mesenchymal stem cells in immune thrombocytopenia

Min Wang, Ru Feng, Jia-min Zhang, Lin-lin Xu, Fei-er Feng, Chen-cong Wang, Qian-ming Wang, Xiao-lu Zhu, Yun He, Jing Xue, Hai-xia Fu, Meng Lv, Yuan Kong, Ying-jun Chang, Lan-ping Xu, Kai-yan Liu, Xiao-jun Huang, Xiao-hui Zhang

Blood Adv (2019) 3 (9): 1416–1428.

https://doi.org/10.1182/bloodadvances.2018026690

Published: 2019

Includes: Supplemental data

Journal Articles

Infused factor VIII–expressing platelets or megakaryocytes as a novel therapeutic strategy for hemophilia A

Randolph B. Lyde, Hyun Sook Ahn, Karen K. Vo, Danuta J. Jarocha, John Tkaczynski, Elsa Treffeisen, Spencer K. Sullivan, Rodney M. Camire, Denise E. Sabatino, Deborah L. French, Mortimer Poncz

Blood Adv (2019) 3 (9): 1368–1378.

https://doi.org/10.1182/bloodadvances.2017007914

Published: 2019

Includes: Supplemental data

Journal Articles

Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation

Alyssa J. Moroi, Nicole M. Zwifelhofer, Matthew J. Riese, Debra K. Newman, Peter J. Newman

Blood Adv (2019) 3 (7): 1154–1166.

https://doi.org/10.1182/bloodadvances.2018026328

Published: 2019

Includes: Supplemental data

Journal Articles

Lin28b regulates age-dependent differences in murine platelet function

Massiel Chavez Stolla, Seana C. Catherman, Paul D. Kingsley, R. Grant Rowe, Anne D. Koniski, Katherine Fegan, Leah Vit, Kathleen E. McGrath, George Q. Daley, James Palis

Blood Adv (2019) 3 (1): 72–82.

https://doi.org/10.1182/bloodadvances.2018020859

Published: 2019

Includes: Supplemental data

Journal Articles

microRNA-22 promotes megakaryocyte differentiation through repression of its target, GFI1

Cary N. Weiss, Keisuke Ito

Blood Adv (2019) 3 (1): 33–46.

https://doi.org/10.1182/bloodadvances.2018023804

Published: 2019

Includes: Supplemental data

Journal Articles

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

Praveen K. Suraneni, Seth J. Corey, Michael J. Hession, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, Chirag Shah, Hui Liu, Amittha Wickrema, Najet Debili, John D. Crispino, Elizabeth A. Eklund, Yolande Chen

Blood Adv (2018) 2 (23): 3540–3552.

https://doi.org/10.1182/bloodadvances.2018021923

Published: 2018

Includes: Multimedia, Supplemental data

NARROW

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions

Transfer to the clinic: refining forward programming of hPSCs to megakaryocytes for platelet production in bioreactors

Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Low-dose decitabine for refractory prolonged isolated thrombocytopenia after HCT: a randomized multicenter trial

Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation

JAK2 S523L, a novel gain-of-function mutation in a critical autoregulatory residue in JAK2 V617F − MPNs

Artificial intelligence–based morphological fingerprinting of megakaryocytes: a new tool for assessing disease in MPN patients

EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis

Human megakaryocytic microparticles induce de novo platelet biogenesis in a wild-type murine model

IκB kinase 2 is not essential for platelet activation

Imetelstat inhibits growth of megakaryocyte colony-forming units from patients with essential thrombocythemia

Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Megakaryocytes package contents into separate α-granules that are differentially distributed in platelets

Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials

Dysregulated megakaryocyte distribution associated with nestin + mesenchymal stem cells in immune thrombocytopenia

Infused factor VIII–expressing platelets or megakaryocytes as a novel therapeutic strategy for hemophilia A

Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation

Lin28b regulates age-dependent differences in murine platelet function

microRNA-22 promotes megakaryocyte differentiation through repression of its target, GFI1

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

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American Society of Hematology

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American Society of Hematology

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