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Klaus H. Metzeler
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Journal Articles

Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML

Clinical Trials & Observations
Aarif M. N. Batcha, Nele Buckup, Stefanos A. Bamopoulos, Vindi Jurinovic, Maja Rothenberg-Thurley, Hanna Gittinger, Bianka Ksienzyk, Annika Dufour, Stephanie Schneider, Mika Kontro, Joseph Saad, Caroline A. Heckmann, Cristina Sauerland, Dennis Görlich, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Ulrich Mansmann, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold
Journal: Blood Advances
Blood Adv (2023) 7 (6): 1040–1044.
DOI: https://doi.org/10.1182/bloodadvances.2022007988
Published: 2023
Includes: Supplemental data
Journal Articles

Differential impact of IDH1 / 2 mutational subclasses on outcome in adult AML: results from a large multicenter study

Clinical Trials & Observations
Jan M. Middeke, Klaus H. Metzeler, Christoph Röllig, Michael Krämer, Jan-Niklas Eckardt, Sebastian Stasik, Philipp A. Greif, Karsten Spiekermann, Maja Rothenberg-Thurley, Utz Krug, Jan Braess, Alwin Krämer, Andreas Hochhaus, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Dennis Görlich, Cristina Sauerland, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Norbert Frickhofen, Richard Noppeney, Ulrich Kaiser, Martin Kaufmann, Desiree Kunadt, Bernhard Wörmann, Katja Sockel, Malte von Bonin, Tobias Herold, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, Hubert Serve, Claudia D. Baldus, Gerhard Ehninger, Johannes Schetelig, Wolfgang Hiddemann, Martin Bornhäuser, Friedrich Stölzel, Christian Thiede
Journal: Blood Advances
Blood Adv (2022) 6 (5): 1394–1405.
DOI: https://doi.org/10.1182/bloodadvances.2021004934
Published: 2022
Includes: Supplemental data
Journal Articles

A clinically applicable gene expression–based score predicts resistance to induction treatment in acute myeloid leukemia

Clinical Trials & Observations
Christian Moser, Vindi Jurinovic, Sabine Sagebiel-Kohler, Bianka Ksienzyk, Aarif M. N. Batcha, Annika Dufour, Stephanie Schneider, Maja Rothenberg-Thurley, Cristina M. Sauerland, Dennis Görlich, Wolfgang E. Berdel, Utz Krug, Ulrich Mansmann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Philipp A. Greif, Sebastian Vosberg, Klaus H. Metzeler, Jörg Kumbrink, Tobias Herold
Journal: Blood Advances
Blood Adv (2021) 5 (22): 4752–4761.
DOI: https://doi.org/10.1182/bloodadvances.2021004814
Published: 2021
Includes: Supplemental data
Journal Articles

The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Silvia Thoene, Tamoghna Mandal, Naidu M. Vegi, Leticia Quintanilla-Martinez, Reinhild Rösler, Sebastian Wiese, Klaus H. Metzeler, Tobias Herold, Torsten Haferlach, Konstanze Döhner, Hartmut Döhner, Luisa Schwarzmüller, Ursula Klingmüller, Christian Buske, Vijay P. S. Rawat, Michaela Feuring-Buske
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3729–3739.
DOI: https://doi.org/10.1182/bloodadvances.2019000761
Published: 2019
Includes: Supplemental data
Journal Articles

Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

Victoria V. Grunwald, Marcus Hentrich, Xaver Schiel, Annika Dufour, Stephanie Schneider, Michaela Neusser, Marion Subklewe, Michael Fiegl, Wolfgang Hiddemann, Karsten Spiekermann, Maja Rothenberg-Thurley, Klaus H. Metzeler
Journal: Blood Advances
Blood Adv (2019) 3 (18): 2696–2699.
DOI: https://doi.org/10.1182/bloodadvances.2019000265
Published: 2019
Includes: Supplemental data
Journal Articles

Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis

Catharina Wenk, Anne-Kathrin Garz, Sonja Grath, Christina Huberle, Denis Witham, Marie Weickert, Roberto Malinverni, Julia Niggemeyer, Michèle Kyncl, Judith Hecker, Charlotta Pagel, Christopher B. Mulholland, Catharina Müller-Thomas, Heinrich Leonhardt, Florian Bassermann, Robert A. J. Oostendorp, Klaus H. Metzeler, Marcus Buschbeck, Katharina S. Götze
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3447–3461.
DOI: https://doi.org/10.1182/bloodadvances.2018022053
Published: 2018
Includes: Supplemental data
Journal Articles

Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA

Nikola P. Konstandin, Friederike Pastore, Tobias Herold, Annika Dufour, Maja Rothenberg-Thurley, Tanja Hinrichsen, Bianka Ksienzyk, Sebastian Tschuri, Stephanie Schneider, Eva Hoster, Wolfgang E. Berdel, Bernhard J. Woermann, Maria C. Sauerland, Jan Braess, Stefan K. Bohlander, Hanns-Georg Klein, Wolfgang Hiddemann, Klaus H. Metzeler, Karsten Spiekermann
Journal: Blood Advances
Blood Adv (2018) 2 (20): 2724–2731.
DOI: https://doi.org/10.1182/bloodadvances.2018016840
Published: 2018
Includes: Supplemental data
Journal Articles

Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission

Clinical Trials & Observations
Sumithira Vasu, Jessica Kohlschmidt, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Deedra Nicolet, Lisa J. Sterling, Heiko Becker, Klaus H. Metzeler, Dimitrios Papaioannou, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Maria R. Baer, Gail J. Roboz, Richard M. Stone, John C. Byrd, Andrew J. Carroll, Clara D. Bloomfield
Journal: Blood Advances
Blood Adv (2018) 2 (13): 1645–1650.
DOI: https://doi.org/10.1182/bloodadvances.2017015222
Published: 2018
Includes: Supplemental data