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Safety and efficacy of zanubrutinib in relapsed/refractory marginal zone lymphoma: final analysis of the MAGNOLIA study
Impaired fibrinolysis and increased clot strength are potential risk factors for thrombosis in lymphoma
Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL
Phase 3 SELENE study: ibrutinib plus BR/R-CHOP in previously treated patients with follicular or marginal zone lymphoma
Vitamin C and D supplementation in acute myeloid leukemia
Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis
Impact of circulating lymphoma cells at diagnosis on outcomes in patients with marginal zone lymphoma: a multicenter cohort study
Intensive hydroxyurea dosing in very young children with sickle cell anemia
Issue Archive
November 28 2023
In this Issue
Table of Contents
INSIDE BLOOD ADVANCES
CLINICAL GUIDELINES
American Society of Hematology 2023 guidelines for management of venous thromboembolism: thrombophilia testing
Saskia Middeldorp,Robby Nieuwlaat,Lisa Baumann Kreuziger,Michiel Coppens,Damon Houghton,Andra H. James,Eddy Lang,Stephan Moll,Tarra Myers,Meha Bhatt,Chatree Chai-Adisaksopha,Luis E. Colunga-Lozano,Samer G. Karam,Yuan Zhang,Wojtek Wiercioch,Holger J. Schünemann,Alfonso Iorio
CLINICAL TRIALS AND OBSERVATIONS
Safety and efficacy of zanubrutinib in relapsed/refractory marginal zone lymphoma: final analysis of the MAGNOLIA study
Clinical Trials & Observations
Stephen Opat,Alessandra Tedeschi,Bei Hu,Kim M. Linton,Pamela McKay,Sophie Leitch,Morton Coleman,Pier Luigi Zinzani,Jie Jin,Mingyuan Sun,Magdalena Sobieraj-Teague,Peter Browett,Xiaoyan Ke,Catherine Thieblemont,Kirit Ardeshna,Fontanet Bijou,Patricia Walker,Eliza A. Hawkes,Shir-Jing Ho,Keshu Zhou,Zhiyu Liang,Jianfeng Xu,Chris Tankersley,Richard Delarue,Melannie Co,Judith Trotman
Impaired fibrinolysis and increased clot strength are potential risk factors for thrombosis in lymphoma
Clinical Trials & Observations
HEALTH SERVICES AND OUTCOMES
Results of VOICE: a global survey of disease-specific knowledge and perspectives of real-world patients with CLL
Constantine Tam,Javier Pinilla-Ibarz,Carolina G. Castillo,Ana Cristina Fenili,Kathryn Huntley,Volkan Karakus,Mervat Mattar,Miguel A. Miroli,Catherine Moura,Miguel Pavlovsky,Fernando Piotrowski,Martin Šimkovič,Stephan Stilgenbauer
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL
Clinical Trials & Observations
Emily C. Liang,Aya Albittar,Jennifer J. Huang,Alexandre V. Hirayama,Erik L. Kimble,Andrew J. Portuguese,Aude Chapuis,Mazyar Shadman,Brian G. Till,Ryan D. Cassaday,Filippo Milano,Hans-Peter Kiem,Stanley R. Riddell,Cameron J. Turtle,David G. Maloney,Jordan Gauthier
International validation of a health-related quality-of-life questionnaire for Hodgkin lymphoma: the EORTC QLQ-HL27
Simone Oerlemans,Fabio Efficace,Omar Shamieh,Fabio Cardoso Borges,Corine de Jong,Dong Dong,Jens Lehmann,Sandra Malak,Duska Petranovic,Christian W. Scholz,Giovanni Caocci,Stefano Molica,Laimonas Griskevicius,Eva Nagele,Anne Bredart,Elisabete Carvalho,Aliki Xochelli,Joost Agelink van Rentergem,Waleed Alrjoob,Anja Mueller,Ana Carolina Freitas,Kim Cocks,Carien Creutzberg,Charalampia Kyriakou,Lonneke van de Poll-Franse
Phase 3 SELENE study: ibrutinib plus BR/R-CHOP in previously treated patients with follicular or marginal zone lymphoma
Clinical Trials & Observations
Loretta J. Nastoupil,Georg Hess,Miguel A. Pavlovsky,Iwona Danielewicz,Jane Freeman,Alejandro Martin García-Sancho,Valeria Glazunova,Andrew Grigg,Jing-Zhou Hou,Ann Janssens,Seok Jin Kim,Zvenyslava Masliak,Pam McKay,Francesco Merli,Wataru Munakata,Hirokazu Nagai,Muhit Özcan,Meir Preis,Tingyu Wang,Melissa Rowe,Monelle Tamegnon,Rui Qin,Todd Henninger,Madeliene Curtis,Donne Bennett Caces,Catherine Thieblemont,Gilles Salles
MYELOID NEOPLASIA
Vitamin C and D supplementation in acute myeloid leukemia
Clinical Trials & Observations
Pierre Luc Mouchel,Emilie Bérard,Suzanne Tavitian,Noémie Gadaud,François Vergez,Jean Baptiste Rieu,Isabelle Luquet,Audrey Sarry,Françoise Huguet,Laetitia Largeaud,Eric Delabesse,Anne Huynh,Sarah Bertoli,Christian Récher
Telomeric repeat-containing RNA is dysregulated in acute myeloid leukemia
Luiz Fernando B. Catto,Leonardo C. Zanelatto,Flavia S. Donaires,Vinicius S. de Carvalho,Bárbara A. Santana,André L. Pinto,Daianne Fantacini,Lucas Eduardo B. de Souza,Natasha P. Fonseca,Bruno S. Telho,Maria Isabel Ayrosa Madeira,Katia Borgia Barbosa Pagnano,Ana Beatriz Firmato,Evandro Maranhão Fagundes,Marcia Higashi,Elenaide Coutinho Nunes,Fabiola Traina,Lorena Lobo de F. Pontes,Eduardo M. Rego,Rodrigo T. Calado
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
VWF–ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion
Helen Fogarty,Azaz Ahmad,Ferdows Atiq,Dearbhla Doherty,Soracha Ward,Ellie Karampini,Aisling Rehill,Gemma Leon,Ciara Byrne,Rosena Geoghegan,Helena Conroy,Mary Byrne,Ulrich Budde,Sonja Schneppenheim,Ciara Sheehan,Noel Ngwenya,Ross I. Baker,Roger J. S. Preston,Emma Tuohy,Corrina McMahon,James S. O’Donnell
TRANSPLANTATION
Unfavorable transcriptome profiles and social disadvantage in hematopoietic cell transplantation: a CIBMTR analysis
Mallory R. Taylor,Steve W. Cole,Joelle Strom,Ruta Brazauskas,K. Scott Baker,Rachel Phelan,David Buchbinder,Betty Hamilton,Hélène Schoemans,Bronwen E. Shaw,Akshay Sharma,Neel S. Bhatt,Sherif M. Badawy,Lena E. Winestone,Jaime M. Preussler,Samantha Mayo,Kareem Jamani,Taiga Nishihori,Michelle A. Lee,Jennifer M. Knight
Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis
Clinical Trials & Observations
Hemant S. Murthy,Mei-Jie Zhang,Karen Chen,Sairah Ahmed,Uday Deotare,Siddhartha Ganguly,Ankit Kansagra,Fotios V. Michelis,Taiga Nishihori,Mrinal Patnaik,Muhammad Bilal Abid,Mahmoud Aljurf,Yasuyuki Arai,Ulrike Bacher,Talha Badar,Sherif M. Badawy,Karen Ballen,Minoo Battiwalla,Amer Beitinjaneh,Nelli Bejanyan,Vijaya Raj Bhatt,Valerie I. Brown,Rodrigo Martino,Jean-Yves Cahn,Paul Castillo,Jan Cerny,Saurabh Chhabra,Edward Copelan,Andrew Daly,Bhagirathbhai Dholaria,Miguel Angel Diaz Perez,César O. Freytes,Michael R. Grunwald,Shahrukh Hashmi,Gerhard C. Hildebrandt,Omer Jamy,Jacinth Joseph,Christopher G. Kanakry,Nandita Khera,Maxwell M. Krem,Yachiyo Kuwatsuka,Hillard M. Lazarus,Lazaros J. Lekakis,Hongtao Liu,Dipenkumar Modi,Pashna N. Munshi,Alberto Mussetti,Neil Palmisiano,Sagar S. Patel,David A. Rizzieri,Sachiko Seo,Mithun Vinod Shah,Akshay Sharma,Melhm Sohl,Scott R. Solomon,Matthew Ulrickson,Celalettin Ustun,Marjolein van der Poel,Leo F. Verdonck,John L. Wagner,Trent Wang,Baldeep Wirk,Amer Zeidan,Mark Litzow,Partow Kebriaei,Christopher S. Hourigan,Daniel J. Weisdorf,Wael Saber,Mohamed A. Kharfan-Dabaja
Risky health behaviors and subsequent late mortality after blood or marrow transplantation: a BMTSS report
Nora Balas,Joshua Richman,Wendy Landier,Sadeep Shrestha,Katia J. Bruxvoort,Lindsey Hageman,Qingrui Meng,Elizabeth Ross,Alysia Bosworth,Hok Sreng Te,F. Lennie Wong,Ravi Bhatia,Stephen J. Forman,Saro H. Armenian,Daniel J. Weisdorf,Smita Bhatia
RESEARCH LETTERS
Impact of circulating lymphoma cells at diagnosis on outcomes in patients with marginal zone lymphoma: a multicenter cohort study
Clinical Trials & Observations
Kaitlin Annunzio,Natalie S. Grover,Rina Li Welkie,Pallawi Torka,Marcus P. Watkins,Andrea Anampa-Guzmán,Montreh Tavakkoli,Timothy S. Oh,Heather Reves,Daniel Jones,Walter Hanel,Beth Christian,Praveen Ramakrishnan Geethakumari,Reem Karmali,Stefan K. Barta,Nancy L. Bartlett,Adam J. Olszewski,Narendranath Epperla
Early quantification of anti-CD19 CAR T cells by flow cytometry predicts response in R/R DLBCL
Viktoria Blumenberg,Galina Busch,Stephan Baumann,Regina Jitschin,Gloria Iacoboni,Laura Gallur,Josu Iraola-Truchuelo,Eva Hoster,Michael Winkelmann,Konstantin Hellwig,Christian Schmidt,Lisa Frölich,Benjamin Tast,Friederike Hildebrand,Kai Rejeski,Franziska Dekorsy,Christian Schmidkonz,Tobias Bäuerle,Wolfgang G. Kunz,Dimitrios Mougiakakos,Fabian Müller,Michael von Bergwelt-Baildon,Pere Barba,Veit L. Bücklein,Andreas Mackensen,Simon Völkl,Marion Subklewe
Intensive hydroxyurea dosing in very young children with sickle cell anemia
Clinical Trials & Observations
Winfred C. Wang,R. Clark Brown,Melissa A. McNaull,Zora R. Rogers,Martha Barton,Meghna R. Dua,Jane S. Hankins,Jeffrey Gossett,Julie Richardson,Jerlym S. Porter,Guolian Kang,Jeremie H. Estepp,for the HUGKISS Investigators
COMMENTARY
ERRATA
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Cover Image
Cover Image
Immunofluorescent staining of a postconception 20-week-old human fetal lung showing a cluster of CD41 expressing cells (green) undergoing endothelial-to-hematopoietic transition (EHT) from neighboring vascular endothelial cadherin-positive endothelium (red). These clusters are also expressing the key EHT transcriptional regulator RUNX-1 (gray), thus suggesting the presence of hemogenic endothelium in the fetal lung. See the article by Yeung et al.
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Clearing the way for new therapies in clonal hematopoiesis