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Diminished humoral and cellular responses to SARS-CoV-2 vaccines in patients with chronic lymphocytic leukemia
Darinaparsin in patients with relapsed or refractory peripheral T-cell lymphoma: results of an Asian phase 2 study
Anti-CD19 CAR T-cell consolidation therapy combined with CD19+ feeding T cells and TKI for Ph+ acute lymphoblastic leukemia
Mosunetuzumab monotherapy is active and tolerable in patients with relapsed/refractory diffuse large B-cell lymphoma
Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Guadecitabine vs treatment choice in newly diagnosed acute myeloid leukemia: a global phase 3 randomized study
Impact of detectable monoclonal protein at diagnosis on outcomes in marginal zone lymphoma: a multicenter cohort study
Phase 2 study of natalizumab plus standard corticosteroid treatment for high-risk acute graft-versus-host disease
Prevalence of frailty and its association with clinical outcomes in myeloproliferative neoplasms: a population-based study
Subclonal TP53 mutations are frequent and predict resistance to radioimmunotherapy in follicular lymphoma
Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia
A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura
Real-world prognostic testing and treatment patterns in CLL/SLL: results from 1462 patients in the informCLL registry
Treatment delays in children and young adults with lymphoma: a report from an East Africa lymphoma cohort study
The utility of biomarkers in acute GVHD prognostication
Issue Archive
September 12 2023
In this Issue
Table of Contents
INSIDE BLOOD ADVANCES
REVIEW ARTICLE
Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD
Nataliya P. Buxbaum,Gerard Socié,Geoffrey R. Hill,Kelli P. A. MacDonald,Victor Tkachev,Takanori Teshima,Stephanie J. Lee,Jerome Ritz,Stefanie Sarantopoulos,Leo Luznik,Defu Zeng,Sophie Paczesny,Paul J. Martin,Steven Z. Pavletic,Kirk R. Schultz,Bruce R. Blazar
CLINICAL TRIALS AND OBSERVATIONS
Diminished humoral and cellular responses to SARS-CoV-2 vaccines in patients with chronic lymphocytic leukemia
Clinical Trials & Observations
Chaitra Ujjani,Ted A. Gooley,Stephen E. Spurgeon,Deborah M. Stephens,Catherine Lai,Catherine M. Broome,Susan O’Brien,Haiying Zhu,Kerry J. Laing,Allison M. Winter,Georgios Pongas,Alexander L Greninger,David M. Koelle,Tanya Siddiqi,Matthew S. Davids,Kerry A. Rogers,Alexey V. Danilov,Amy Sperling,Brian Tu,Tyler Sorensen,Kelsey Launchbury,Carlissa J. Burrow,Genesis Quezada,Joshua A. Hill,Mazyar Shadman,Philip A. Thompson
Darinaparsin in patients with relapsed or refractory peripheral T-cell lymphoma: results of an Asian phase 2 study
Clinical Trials & Observations
Won-Seog Kim,Noriko Fukuhara,Dok-Hyun Yoon,Kazuhito Yamamoto,Toshiki Uchida,Eiju Negoro,Koji Izutsu,Yasuhito Terui,Hideaki Nakajima,Kiyoshi Ando,Youko Suehiro,Hye Jin Kang,Po-Shen Ko,Fumiko Nagahama,Yusuke Sonehara,Hirokazu Nagai,Hwei-Fang Tien,Yok-Lam Kwong,Kensei Tobinai
Anti-CD19 CAR T-cell consolidation therapy combined with CD19+ feeding T cells and TKI for Ph+ acute lymphoblastic leukemia
Clinical Trials & Observations
Li-Yun Chen,Wen-Jie Gong,Ming-Hao Li,Hai-Xia Zhou,Ming-Zhu Xu,Chong-Sheng Qian,Li-Qing Kang,Nan Xu,Zhou Yu,Man Qiao,Tong-Tong Zhang,Ling Zhang,Zheng-Long Tian,Ai-Ning Sun,Lei Yu,De-Pei Wu,Sheng-Li Xue
Mosunetuzumab monotherapy is active and tolerable in patients with relapsed/refractory diffuse large B-cell lymphoma
Clinical Trials & Observations
Nancy L. Bartlett,Sarit Assouline,Pratyush Giri,Stephen J. Schuster,Chan Y. Cheah,Matthew Matasar,Gareth P. Gregory,Dok Hyun Yoon,Mazyar Shadman,Keith Fay,Sung-Soo Yoon,Carlos Panizo,Ian Flinn,Anna Johnston,Francesc Bosch,Laurie H. Sehn,Michael C. Wei,Shen Yin,Iris To,Chi-Chung Li,Huang Huang,Antonia Kwan,Elicia Penuel,Lihua E. Budde
Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Clinical Trials & Observations
Anna B. Halpern,Eduardo Rodríguez-Arbolí,Megan Othus,Kelsey-Leigh A. Garcia,Mary-Elizabeth M. Percival,Ryan D. Cassaday,Vivian G. Oehler,Pamela S. Becker,Jacob S. Appelbaum,Janis L. Abkowitz,Johnnie J. Orozco,Siobán B. Keel,Paul C. Hendrie,Bart L. Scott,M. Cristina Ghiuzeli,Elihu H. Estey,Roland B. Walter
Guadecitabine vs treatment choice in newly diagnosed acute myeloid leukemia: a global phase 3 randomized study
Clinical Trials & Observations
Pierre Fenaux,Marco Gobbi,Patricia L. Kropf,Jean-Pierre J. Issa,Gail J. Roboz,Jiri Mayer,Jürgen Krauter,Tadeusz Robak,Hagop Kantarjian,Jan Novak,Wieslaw. W. Jedrzejczak,Xavier Thomas,Mario Ojeda-Uribe,Yasushi Miyazaki,Yoo Hong Min,Su-Peng Yeh,Joseph Brandwein,Liana Gercheva-Kyuchukova,Judit Demeter,Elizabeth Griffiths,Karen Yee,Konstanze Döhner,Yong Hao,Harold Keer,Mohammad Azab,Hartmut Döhner
Impact of detectable monoclonal protein at diagnosis on outcomes in marginal zone lymphoma: a multicenter cohort study
Clinical Trials & Observations
Narendranath Epperla,Qiuhong Zhao,Reem Karmali,Pallawi Torka,Lauren Shea,Timothy S. Oh,Andrea Anampa-Guzmán,Heather Reves,Montreh Tavakkoli,Irl Brian Greenwell,Emily Hansinger,Elvira Umyarova,Kaitlin Annunzio,Yazeed Sawalha,Beth Christian,Colin Thomas,Stefan K. Barta,Praveen Ramakrishnan Geethakumari,Nancy L. Bartlett,Natalie S. Grover,Adam J. Olszewski
Phase 2 study of natalizumab plus standard corticosteroid treatment for high-risk acute graft-versus-host disease
Clinical Trials & Observations
Monzr M. Al Malki,Kaitlyn London,Janna Baez,Yu Akahoshi,William J. Hogan,Aaron Etra,Hannah Choe,Elizabeth Hexner,Amelia Langston,Sunil Abhyankar,Doris M. Ponce,Zachariah DeFilipp,Carrie L. Kitko,Kehinde Adekola,Ran Reshef,Francis Ayuk,Alexandra Capellini,Chantiya Chanswangphuwana,Matthias Eder,Gilbert Eng,Isha Gandhi,Stephan Grupp,Sigrun Gleich,Ernst Holler,Nora Rebeka Javorniczky,Stelios Kasikis,Steven Kowalyk,George Morales,Umut Özbek,Wolf Rösler,Nikolaos Spyrou,Gregory Yanik,Rachel Young,Yi-Bin Chen,Ryotaro Nakamura,James L. M. Ferrara,John E. Levine
HEALTH SERVICES AND OUTCOMES
Prevalence of frailty and its association with clinical outcomes in myeloproliferative neoplasms: a population-based study
Clinical Trials & Observations
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY AND IMMUNOTHERAPY
Immune profiling after allogeneic hematopoietic cell transplantation in pediatric acute myeloid leukemia
Sanam Shahid,Nicholas Ceglia,Jean-Benoît Le Luduec,Andrew McPherson,Barbara Spitzer,Theodota Kontopoulos,Viktoria Bojilova,M. Kazim Panjwani,Mikhail Roshal,Sohrab P. Shah,Omar Abdel-Wahab,Benjamin Greenbaum,Katharine C. Hsu
LYMPHOID NEOPLASIA
Minimal residual disease in patients with diffuse large B-cell lymphoma undergoing autologous stem cell transplantation
Reid W. Merryman,Robert A. Redd,Eleanor Taranto,Gulrayz Ahmed,Erin Jeter,Kristin M. McHugh,Jennifer R. Brown,Jennifer L. Crombie,Matthew S. Davids,David C. Fisher,Arnold S. Freedman,Eric Jacobsen,Caron A. Jacobson,Austin I. Kim,Ann S. LaCasce,Samuel Y. Ng,Oreofe O. Odejide,Erin M. Parry,Heather Jacene,Hyesun Park,Parastoo B. Dahi,Yago Nieto,Robin M. Joyce,Yi-Bin Chen,Margaret A. Shipp,Alex F. Herrera,Philippe Armand
Chimeric antigen receptor T-cell therapy yields similar outcomes in patients with and without cytokine release syndrome
Shakthi T. Bhaskar,Vivek G. Patel,David L. Porter,Stephen J. Schuster,Loretta J. Nastoupil,Miguel-Angel Perales,Ana Alarcon Tomas,Michael R. Bishop,Joseph P. McGuirk,Richard T. Maziarz,Andy I. Chen,Veronika Bachanova,Joseph E. Maakaron,Peter A. Riedell,Olalekan O. Oluwole
Retrospective characterization of nodal marginal zone lymphoma
Robert Stuver,Esther Drill,David Qualls,Michelle Okwali,Connie Lee Batlevi,Philip C. Caron,Ahmet Dogan,Zachary D. Epstein-Peterson,Lorenzo Falchi,Paul A. Hamlin,Steven M. Horwitz,Brandon S. Imber,Andrew M. Intlekofer,William T. Johnson,Niloufer Khan,Anita Kumar,Oscar B. Lahoud,Jennifer Kimberly Lue,Matthew J. Matasar,Alison J. Moskowitz,Ariela Noy,Colette N. Owens,M. Lia Palomba,Heiko Schöder,Santosha A. Vardhana,Joachim Yahalom,Andrew D. Zelenetz,Gilles Salles,David J. Straus
The SALENTO prognostic model for limited-stage peripheral T-cell lymphoma from the International T-Cell Project Network
Greg Hapgood,Monica Civallero,Yana Stepanishyna,Julie Vose,Monica Elena Cabrera,Ranjana H. Advani,Stefano A. Pileri,Martina Manni,Steven M. Horwitz,Francine M. Foss,Felicitas Hitz,John Radford,Ivan Dlouhy,Carlos Chiattone,Won Seog Kim,Tetiana Skrypets,Arnon Nagler,Judith Trotman,Stefano Luminari,Massimo Federico,on behalf of the International T-Cell Project
Subclonal TP53 mutations are frequent and predict resistance to radioimmunotherapy in follicular lymphoma
Clinical Trials & Observations
W. Richard Burack,Hongli Li,Diana Adlowitz,Janice M. Spence,Lisa M. Rimsza,Mazyar Shadman,Catherine M. Spier,Mark S. Kaminski,John P. Leonard,Michael L. Leblanc,Sonali M. Smith,Jonathan W. Friedberg
TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy
William T. Johnson,Nivetha Ganesan,Zachary D. Epstein-Peterson,Alison J. Moskowitz,Robert N. Stuver,Catherine R. Maccaro,Natasha Galasso,Tiffany Chang,Niloufer Khan,Umut Aypar,Natasha E. Lewis,Andrew D. Zelenetz,M. Lia Palomba,Matthew J. Matasar,Ariela Noy,Audrey M. Hamilton,Paul Hamlin,Philip C. Caron,David J. Straus,Andrew M. Intlekofer,Connie Lee Batlevi,Anita Kumar,Colette N. Owens,Craig S. Sauter,Lorenzo Falchi,Jennifer K. Lue,Santosha A. Vardhana,Gilles Salles,Ahmet Dogan,Nikolaus D. Schultz,Maria E. Arcila,Steven M. Horwitz
MYELOID NEOPLASIA
Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia
Clinical Trials & Observations
Joseph G. W. McCarter,David Nemirovsky,Christopher A. Famulare,Noushin Farnoud,Abhinita S. Mohanty,Zoe S. Stone-Molloy,Jordan Chervin,Brian J. Ball,Zachary D. Epstein-Peterson,Maria E. Arcila,Aaron J. Stonestrom,Andrew Dunbar,Sheng F. Cai,Jacob L. Glass,Mark B. Geyer,Raajit K. Rampal,Ellin Berman,Omar I. Abdel-Wahab,Eytan M. Stein,Martin S. Tallman,Ross L. Levine,Aaron D. Goldberg,Elli Papaemmanuil,Yanming Zhang,Mikhail Roshal,Andriy Derkach,Wenbin Xiao
Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting
Enrico Attardi,Arianna Savi,Beatrice Borsellino,Alfonso Piciocchi,Marta Cipriani,Tiziana Ottone,Emiliano Fabiani,Mariadomenica Divona,Serena Travaglini,Maria Rosaria Pascale,Hussein Awada,Arda Durmaz,Valeria Visconte,Matteo Giovanni Della Porta,Adriano Venditti,Jaroslaw P. Maciejewski,Carmelo Gurnari,Maria Teresa Voso
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
Eltrombopag in patients with chronic immune thrombocytopenia in Asia-Pacific, the Middle East, and Turkey: final analysis of CITE
Raymond Siu Ming Wong,İrfan Yavaşoğlu,Mohamed A. Yassin,Pınar Tarkun,Sung-Soo Yoon,Xie Wei,Ashraf Elghandour,Pantep Angchaisuksiri,Mehmet Ozcan,Renchi Yang,Mervat Mattar,Masiur Rahman,Sara Ingles,Michael Goldbrunner,Jennifer A. Frueh,Jun Ho Jang
Platelet functional abnormalities in pediatric patients with kaposiform hemangioendothelioma/Kasabach-Merritt phenomenon
Alexey A. Martyanov,Ivan P. Tesakov,Lili A. Khachatryan,Olga I. An,Anna E. Boldova,Anastasia A. Ignatova,Ekaterina M. Koltsova,Julia-Jessica D. Korobkin,Nadezhda A. Podoplelova,Galina S. Svidelskaya,Eugenia Yushkova,Galina A. Novichkova,Johannes A. Eble,Mikhail A. Panteleev,Dmitrii V. Kalinin,Anastasia N. Sveshnikova
RED CELLS, IRON, AND ERYTHROPOIESIS
Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects
Anne-Sophie Cloos,Hélène Pollet,Amaury Stommen,Mauriane Maja,Maxime Lingurski,Bénédicte Brichard,Catherine Lambert,Patrick Henriet,Christophe Pierreux,Sébastien Pyr dit Ruys,Patrick Van Der Smissen,Miikka Vikkula,Laurent Gatto,Manon Martin,Pascal Brouillard,Didier Vertommen,Donatienne Tyteca
THROMBOSIS AND HEMOSTASIS
A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura
Clinical Trials & Observations
Tanja Falter,Heidi Rossmann,Laure de Waele,Charlotte Dekimpe,Charis von Auer,Nadine Müller-Calleja,Friederike Häuser,Adriana Degreif,Dana Marandiuc,Xavier Messmer,Martin Sprinzl,Karl J. Lackner,Kerstin Jurk,Karen Vanhoorelbeke,Bernhard Lämmle
TRANSFUSION MEDICINE
TRANSPLANTATION
Novel risk assessment for the intensity of conditioning regimen in older patients
Yu Akahoshi,Yuma Tada,Emiko Sakaida,Machiko Kusuda,Noriko Doki,Naoyuki Uchida,Takahiro Fukuda,Masatsugu Tanaka,Masashi Sawa,Yuta Katayama,Ken-ichi Matsuoka,Yukiyasu Ozawa,Makoto Onizuka,Junya Kanda,Yoshinobu Kanda,Yoshiko Atsuta,Hideki Nakasone
Intestinal permeability in patients undergoing stem cell transplantation correlates with systemic acute phase responses and dysbiosis
YunZu Michele Wang,Sheyar Abdullah,Nathan Luebbering,Lucille Langenberg,Alexandra Duell,Kelly Lake,Adam Lane,Brian Hils,Ormarie Vazquez Silva,Monica Trapp,Kodandaramireddy Nalapareddy,Jane Koo,Lee A. Denson,Sonata Jodele,David B. Haslam,William A. Faubion,Stella M. Davies,Pooja Khandelwal
RESEARCH LETTERS
Flow cytometry as a fast, cost-effective tool to assess IGHV mutational status in CLL
Guillaume Couillez,Pierre Morel,Valentin Clichet,Ludivine Fourdrain,Caroline Delette,Véronique Harrivel,Brigitte Gubler,Camille Rottier,Sophie Derreumaux,Emilie Margat,Loic Garcon,Jean-Pierre Marolleau,Thomas Boyer
Real-world prognostic testing and treatment patterns in CLL/SLL: results from 1462 patients in the informCLL registry
Clinical Trials & Observations
Anthony R. Mato,Nilanjan Ghosh,Jeff P. Sharman,Danielle Brander,Meghan Gutierrez,Qing Huang,Linda H. Wu,Alex Young,Sandhya Upasani,Maoko Naganuma,Jacqueline C. Barrientos
No sex differential in relative survival among older patients with DLBCL treated with R-CHOP21: a population-based study
Emma E. Geerdes,Müjde Durmaz,Pieternella J. Lugtenburg,Martine E. D. Chamuleau,Otto Visser,Djamila E. Issa,Rolf E. Brouwer,Eduardus F. M. Posthuma,Josée M. Zijlstra,Marie José Kersten,Avinash G. Dinmohamed
Treatment delays in children and young adults with lymphoma: a report from an East Africa lymphoma cohort study
Global Advances
William Frank Mawalla,Liz Morrell,Lulu Chirande,Caroline Achola,Hadija Mwamtemi,Godlove Sandi,Salama Mahawi,Atukuzwe Kahakwa,Paul Ntemi,Nabalende Hadija,Elifuraha Mkwizu,Clara Chamba,Dimitris Vavoulis,Anna Schuh
The utility of biomarkers in acute GVHD prognostication
Clinical Trials & Observations
Nikolaos Spyrou,Yu Akahoshi,Francis Ayuk,Ernst Holler,Hannah Choe,Aaron Etra,William J. Hogan,Wolf Rösler,Elizabeth Hexner,Zachariah DeFilipp,Ran Reshef,Chantiya Chanswangphuwana,Muna Qayed,Sabrina Kraus,Matthias Eder,Nora Rebeka Javorniczky,Stephan A. Grupp,Carrie L. Kitko,Pietro Merli,Paibel Aguayo-Hiraldo,Matthias Wölfl,Janna Baez,Rahnuma Beheshti,Gilbert Eng,Sigrun Gleich,Nikolaos Katsivelos,Alina Khan,Steven Kowalyk,George Morales,Rachel Young,Ryotaro Nakamura,Yi-Bin Chen,John E. Levine,James L. M. Ferrara
ERRATUM
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Cover Image
Cover Image
Bone marrow biopsy specimen from a male pediatric patient with acute myeloid leukemia (unknown driver) at diagnosis, stained with hematoxylin and eosin. See the article by Dean et al.
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Clinical Trials & Observations