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STIMULUS REPORT

Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia
Clinical Trials & Observations

Sabrin Tahri,Tarek H. Mouhieddine,Robert Redd,Luisa Lampe,Katarina I. Nilsson,Habib El-Khoury,Nang Kham Su,Amin H. Nassar,Elio Adib,Govind Bindra,Sarah Abou Alaiwi,Lorenzo Trippa,David P. Steensma,Jorge J. Castillo,Steven P. Treon,Irene M. Ghobrial,Adam S. Sperling

View Articletitled, Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia

Supplemental data

Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand

Michelle L. Stoller,Indranil Basak,Frederik Denorme,Jesse W. Rowley,James Alsobrooks,Krishna Parsawar,Marvin T. Nieman,Christian Con Yost,Justin R. Hamilton,Paul F. Bray,Robert A. Campbell

View Articletitled, Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand

Supplemental data

Modulating endothelial cells with EGFL7 to diminish aGVHD after allogeneic bone marrow transplantation in mice

Adrienne M. Dorrance,Moutuaata M. Moutuou,Chinmayee Goda,Natalie E. Sell,Sonu Kalyan,Malith Karunasiri,Rohan Kulkarni,Marie Goulard,Sofia Kolovich,Alexander Rudich,Eric Naumann,Antoine Ackaoui,Charles-Etienne Bigras,Francis Daudelin,Ramiro Garzon,Parvathi Ranganathan,Martin Guimond

View Articletitled, Modulating endothelial cells with EGFL7 to diminish aGVHD after allogeneic bone marrow transplantation in mice

Supplemental data

COVID-19 and CAR T cells: a report on current challenges and future directions from the EPICOVIDEHA survey by EHA-IDWP
Clinical Trials & Observations

View Articletitled, COVID-19 and CAR T cells: a report on current challenges and future directions from the EPICOVIDEHA survey by EHA-IDWP

Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation
Clinical Trials & Observations

View Articletitled, Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation

Supplemental data

SYSTEMATIC REVIEW

Immunogenicity of COVID-19 vaccines in patients with hematologic malignancies: a systematic review and meta-analysis
Clinical Trials & Observations

Joanne S. K. Teh,Julien Coussement,Zoe C. F. Neoh,Tim Spelman,Smaro Lazarakis,Monica A. Slavin,Benjamin W. Teh

View Articletitled, Immunogenicity of COVID-19 vaccines in patients with hematologic malignancies: a systematic review and meta-analysis

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy
Clinical Trials & Observations

View Articletitled, Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy

Supplemental data

Hematologic malignancies magnify the effect of body mass index on insulin resistance in cancer survivors
Clinical Trials & Observations

Melis Sahinoz,James M. Luther,Mona Mashayekhi,Dae Kwang Jung,T. Alp Ikizler,Brian G. Engelhardt

View Articletitled, Hematologic malignancies magnify the effect of body mass index on insulin resistance in cancer survivors

Supplemental data

An international analysis evaluating frontline bendamustine with rituximab in extranodal marginal zone lymphoma
Clinical Trials & Observations

View Articletitled, An international analysis evaluating frontline bendamustine with rituximab in extranodal marginal zone lymphoma

Impact of comorbidity in older patients with peripheral T-cell lymphoma: an international retrospective analysis of 891 patients
Clinical Trials & Observations

Monica Mead,Henrik Cederleuf,Maja Björklund,Xiaoyan Wang,Thomas Relander,Mats Jerkeman,Daria Gaut,Sarah Larson,Fredrik Ellin

View Articletitled, Impact of comorbidity in older patients with peripheral T-cell lymphoma: an international retrospective analysis of 891 patients

Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib
Clinical Trials & Observations

Catherine C. Smith,Mark J. Levis,Alexander E. Perl,Jason E. Hill,Matt Rosales,Erkut Bahceci

View Articletitled, Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib

Supplemental data

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for higher-risk myelodysplastic syndromes
Clinical Trials & Observations

Amer M. Zeidan,Isaac Boss,C. L. Beach,Wilbert B. Copeland,Ethan Thompson,Brian A. Fox,Vanessa E. Hasle,Ken Ogasawara,James Cavenagh,Lewis R. Silverman,Maria Teresa Voso,Andrzej Hellmann,Mar Tormo,Tim O’Connor,Alessandro Previtali,Shelonitda Rose,Guillermo Garcia-Manero

View Articletitled, A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for higher-risk myelodysplastic syndromes

Supplemental data

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for older patients with AML
Clinical Trials & Observations

Amer M. Zeidan,Isaac Boss,C. L. Beach,Wilbert B. Copeland,Ethan Thompson,Brian A. Fox,Vanessa E. Hasle,Andrzej Hellmann,David C. Taussig,Mar Tormo,Maria Teresa Voso,James Cavenagh,Tim O’Connor,Alessandro Previtali,Shelonitda Rose,Lewis R. Silverman

View Articletitled, A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for older patients with AML

Supplemental data

HEMATOPOIESIS AND STEM CELLS

Machine learning–based scoring models to predict hematopoietic stem cell mobilization in allogeneic donors

Jingyu Xiang,Min Shi,Mark A. Fiala,Feng Gao,Michael P. Rettig,Geoffrey L. Uy,Mark A. Schroeder,Katherine N. Weilbaecher,Keith E. Stockerl-Goldstein,Shamim Mollah,John F. DiPersio

View Articletitled, Machine learning–based scoring models to predict hematopoietic stem cell mobilization in allogeneic donors

Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia

View Articletitled, Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia

Supplemental data

Infectious complications in patients with relapsed refractory multiple myeloma after BCMA CAR T-cell therapy

Swetha Kambhampati,Ying Sheng,Chiung-Yu Huang,Sophia Bylsma,Mimi Lo,Vanessa Kennedy,Kelsey Natsuhara,Thomas Martin,Jeffrey Wolf,Nina Shah,Sandy W. Wong

View Articletitled, Infectious complications in patients with relapsed refractory multiple myeloma after BCMA CAR T-cell therapy

Supplemental data

Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy
Clinical Trials & Observations

Krishna R. Juluri,Qian Vicky Wu,Jenna Voutsinas,Jue Hou,Alexandre V. Hirayama,Erin Mullane,Nancy Miles,David G. Maloney,Cameron J. Turtle,Merav Bar,Jordan Gauthier

View Articletitled, Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy

Supplemental data

Antigen-specific immunotherapy with apitopes suppresses generation of FVIII inhibitor antibodies in HLA-transgenic mice

Katrien Pletinckx,Kirsty S. Nicolson,Heather B. Streeter,William J. Sanderson,Evelien Schurgers,Lotta Jansson,David C. Wraith

View Articletitled, Antigen-specific immunotherapy with apitopes suppresses generation of FVIII inhibitor antibodies in HLA-transgenic mice

Supplemental data

Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis

Frank Y. Huang,Pierre Cunin,Felix A. Radtke,Roxane Darbousset,Ricardo Grieshaber-Bouyer,Peter A. Nigrovic

View Articletitled, Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis

Supplemental data

Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing

Dieke J. van Rees,Maximilian Brinkhaus,Bart Klein,Paul Verkuijlen,Anton T.J. Tool,Karin Schornagel,Louise W. Treffers,Michel van Houdt,Arnon P. Kater,Gestur Vidarsson,Andrew R. Gennery,Taco W. Kuijpers,Robin van Bruggen,Hanke L. Matlung,Timo K. van den Berg

View Articletitled, Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing

Supplemental data

Characterization of extramedullary disease in B-ALL and response to CAR T-cell therapy
Clinical Trials & Observations

Elizabeth M. Holland,Bonnie Yates,Alex Ling,Constance M. Yuan,Hao-Wei Wang,Maryalice Stetler-Stevenson,Michael LaLoggia,John C. Molina,Daniel A. Lichtenstein,Daniel W. Lee,John A. Ligon,Haneen Shalabi,Mark A. Ahlman,Nirali N. Shah

View Articletitled, Characterization of extramedullary disease in B-ALL and response to CAR T-cell therapy

Supplemental data

GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial
Clinical Trials & Observations

View Articletitled, GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial

Supplemental data

LYMPHOID NEOPLASIA

Junctional adhesion molecule C expression specifies a CD138^low/neg multiple myeloma cell population in mice and humans

Andreas Brandl,Antonio G. Solimando,Zeinab Mokhtari,Paula Tabares,Juliane Medler,Hannah Manz,Matteo Claudio Da Vià,Giorgio A. Croci,Miriam Kurzwart,Sina Thusek,Theresa Schneider,Regina Ebert,Franz Jakob,Hermann Einsele,Andreas Beilhack

View Articletitled, Junctional adhesion molecule C expression specifies a CD138low/neg multiple myeloma cell population in mice and humans

Supplemental data

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma
Clinical Trials & Observations

View Articletitled, IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Supplemental data

Autologous stem cell transplantation for large B-cell lymphoma with secondary central nervous system involvement

View Articletitled, Autologous stem cell transplantation for large B-cell lymphoma with secondary central nervous system involvement

Supplemental data

A somatic UBA2 variant preceded ETV6-RUNX1 in the concordant BCP-ALL of monozygotic twins

Benedicte Bang,Jesper Eisfeldt,Gisela Barbany,Arja Harila-Saari,Mats Heyman,Vasilios Zachariadis,Fulya Taylan,Ann Nordgren

View Articletitled, A somatic UBA2 variant preceded ETV6-RUNX1 in the concordant BCP-ALL of monozygotic twins

Supplemental data

Targeting CD70 in cutaneous T-cell lymphoma using an antibody-drug conjugate in patient-derived xenograft models

Chi-Heng Wu,Linlin Wang,Chen-Yen Yang,Kwun Wah Wen,Brian Hinds,Ryan Gill,Frank McCormick,Mark Moasser,Laura Pincus,Weiyun Z. Ai

View Articletitled, Targeting CD70 in cutaneous T-cell lymphoma using an antibody-drug conjugate in patient-derived xenograft models

Supplemental data

Clonotype pattern in T-cell lymphomas map the cell of origin to immature lymphoid precursors

Aishwarya Iyer,Dylan Hennessey,Robert Gniadecki

View Articletitled, Clonotype pattern in T-cell lymphomas map the cell of origin to immature lymphoid precursors

Supplemental data

Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma

Anusara Daenthanasanmak,Richard N. Bamford,Makoto Yoshioka,Shyh-Ming Yang,Philip Homan,Baktiar Karim,Bonita R. Bryant,Michael N. Petrus,Craig J. Thomas,Patrick L. Green,Milos D. Miljkovic,Kevin C. Conlon,Thomas A. Waldmann

View Articletitled, Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma

Supplemental data

Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements

Leonie Frauenfeld,Natalia Castrejon-de-Anta,Joan Enric Ramis-Zaldivar,Sebastian Streich,Julia Salmerón-Villalobos,Franziska Otto,Annika Katharina Mayer,Julia Steinhilber,Magda Pinyol,Barbara Mankel,Colleen Ramsower,Irina Bonzheim,Falko Fend,Lisa M. Rimsza,Itziar Salaverria,Elias Campo,Olga Balagué,Leticia Quintanilla-Martinez

View Articletitled, Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements

Supplemental data

SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia

Lauren M. Brown,Soroor Hediyeh-zadeh,Teresa Sadras,Hannah Huckstep,Jarrod J. Sandow,Ray C. Bartolo,Hansen J. Kosasih,Nadia M. Davidson,Breon Schmidt,Stefan Bjelosevic,Ricky Johnstone,Andrew I. Webb,Seong L. Khaw,Alicia Oshlack,Melissa J. Davis,Paul G. Ekert

View Articletitled, SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia

Supplemental data

A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL

Kohta Miyawaki,Koji Kato,Takeshi Sugio,Kensuke Sasaki,Hiroaki Miyoshi,Yuichiro Semba,Yoshikane Kikushige,Yasuo Mori,Yuya Kunisaki,Hiromi Iwasaki,Toshihiro Miyamoto,Frank C. Kuo,Jon C. Aster,Koichi Ohshima,Takahiro Maeda,Koichi Akashi

View Articletitled, A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL

Supplemental data

MYELOID NEOPLASIA

Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2^P95H mutation

Jane Jialu Xu,Alistair M. Chalk,Iva Nikolic,Kaylene J. Simpson,Monique F. Smeets,Carl R. Walkley

View Articletitled, Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2P95H mutation

Supplemental data

Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses
Clinical Trials & Observations

View Articletitled, Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses

Supplemental data

CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones

Roos Houtsma,Nisha K. van der Meer,Kees Meijer,Linde M. Morsink,Shanna M. Hogeling,Carolien M. Woolthuis,Emanuele Ammatuna,Marije T. Nijk,Bauke de Boer,Gerwin Huls,André B. Mulder,Jan Jacob Schuringa

View Articletitled, CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones

Supplemental data

Coping strategies in patients with acute myeloid leukemia

Hermioni L. Amonoo,Monica H. Bodd,Matthew J. Reynolds,Ashley M. Nelson,Richard Newcomb,Patrick Connor Johnson,Tejaswini M. Dhawale,Rachel Plotke,Lauren Heuer,Sabah Gillani,Daniel Yang,Emma C. Deary,Elizabeth Daskalakis,Lauren Goldschen,Andrew Brunner,Amir T. Fathi,Thomas W. LeBlanc,Areej El-Jawahri

View Articletitled, Coping strategies in patients with acute myeloid leukemia

Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Inflammasome activation in neutrophils of patients with severe COVID-19

Karen Aymonnier,Julie Ng,Laura E. Fredenburgh,Katherin Zambrano-Vera,Patrick Münzer,Sarah Gutch,Shoichi Fukui,Michael Desjardins,Meera Subramaniam,Rebecca M Baron,Benjamin A. Raby,Mark A. Perrella,James A. Lederer,Denisa D. Wagner

View Articletitled, Inflammasome activation in neutrophils of patients with severe COVID-19

Supplemental data

PLATELETS AND THROMBOPOIESIS

A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD

Loredana Bury,Emanuela Falcinelli,Haripriya Kuchi Bhotla,Anna Maria Mezzasoma,Giuseppe Guglielmini,Alexander Tischer,Laurie Moon-Tasson,Matthew Auton,Paolo Gresele

View Articletitled, A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD

Supplemental data

G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1

View Articletitled, G protein–coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1

Supplemental data

TRANSPLANTATION

The day 100 score predicts moderate to severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation
Clinical Trials & Observations

Elisabetta Metafuni,Irene Maria Cavattoni,Teresa Lamparelli,Anna Maria Raiola,Anna Ghiso,Federica Galaverna,Francesca Gualandi,Carmen Di Grazia,Alida Dominietto,Riccardo Varaldo,Alessio Signori,Patrizia Chiusolo,Federica Sora’,Sabrina Giammarco,Luca Laurenti,Simona Sica,Emanuele Angelucci,Andrea Bacigalupo

View Articletitled, The day 100 score predicts moderate to severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation

Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation
Clinical Trials & Observations

Rachael Hough,Andre Lopes,Pip Patrick,Nigel Russell,Kavita Raj,Eleni Tholouli,John A. Snowden,Matthew Collin,Nadjet El-Mehidi,Anthony Lawrie,Laura Clifton-Hadley,Paul Veys,Charles Craddock,Stephen Mackinnon,Gordon Cook,Bronwen Shaw,David Marks

View Articletitled, Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation

Supplemental data

RESEARCH LETTER

SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia

Jacob Appelbaum,Donald M. Arnold,John G. Kelton,Terry Gernsheimer,Stefan D. Jevtic,Nikola Ivetic,James W. Smith,Ishac Nazy

View Articletitled, SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia

NPM1 gene mutations can be confidently identified in blood DNA months before de novo AML onset
Clinical Trials & Observations

Pedro M. Quiros,Muxin Gu,Clea Barcena,Vivek Iyer,George S. Vassiliou

View Articletitled, NPM1 gene mutations can be confidently identified in blood DNA months before de novo AML onset

Supplemental data

COMMENTARY

Sustainability of low maternal mortality in pregnant women with SCD in a low-resource setting
Global Advances

Alim Swarray-Deen,Eugenia V. Asare,Ruth Ayettey Brew,John Benaiah Ayete-Nyampong,Yvonne Dei-Adomakoh,Edeghonghon Olayemi,Enoch Mensah,Yvonne Osei-Bonsu,Selina Crabbe,William K. Ghunney,Charles Hayfron-Benjamin,Titus Beyuo,Theodore Boafor,Adetola A. Kassim,Mark Rodeghier,Michael R. DeBaun,Samuel A. Oppong

View Articletitled, Sustainability of low maternal mortality in pregnant women with SCD in a low-resource setting

A third dose of mRNA-1273 vaccine improves SARS-CoV-2 immunity in HCT recipients with low antibody response after 2 doses

Elena Pettini,Annalisa Ciabattini,Gabiria Pastore,Jacopo Polvere,Simone Lucchesi,Fabio Fiorino,Francesca Montagnani,Alessandro Bucalossi,Monica Tozzi,Giuseppe Marotta,Donata Medaglini

View Articletitled, A third dose of mRNA-1273 vaccine improves SARS-CoV-2 immunity in HCT recipients with low antibody response after 2 doses

Does ruxolitinib really prolong survival in individuals with myelofibrosis? The never-ending story
Clinical Trials & Observations

Giovanni Barosi,Robert Peter Gale

View Articletitled, Does ruxolitinib really prolong survival in individuals with myelofibrosis? The never-ending story

ERRATA

Völker LA, Kaufeld J, Miesbach W, et al. Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood Adv. 2020;4(13):3085-3092.

View Articletitled, Völker LA, Kaufeld J, Miesbach W, et al. Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura. Blood Adv. 2020;4(13):3085-3092.

Xu S, Wang S, Xing S, et al. KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2. Blood Adv. 2021;5(17):3241-3253.

View Articletitled, Xu S, Wang S, Xing S, et al. KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2. Blood Adv. 2021;5(17):3241-3253.

Samra B, Khoury JD, Morita K, et al. Long-term outcome of hyper-CVAD-R for Burkitt leukemia/lymphoma and high-grade B-cell lymphoma: focus on CNS relapse. Blood Adv. 2021;5(20):3913-3918.

View Articletitled, Samra B, Khoury JD, Morita K, et al. Long-term outcome of hyper-CVAD-R for Burkitt leukemia/lymphoma and high-grade B-cell lymphoma: focus on CNS relapse. Blood Adv. 2021;5(20):3913-3918.

Cover Image

Cover Image

A confocal microscopy image showing a neutrophil (red, anti-Ly6G AF594) engulfed by a megakaryocyte (green, anti-CD41 AF488) in a cell-in-cell interaction called emperipolesis. Hoechst 33342 (blue) was used for nuclear staining. See the article by Huang et al.
Front Matter
Editorial Board

Issue Archive

Table of Contents

STIMULUS REPORT

Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia Clinical Trials & Observations

COVID-19 and CAR T cells: a report on current challenges and future directions from the EPICOVIDEHA survey by EHA-IDWP Clinical Trials & Observations

Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation Clinical Trials & Observations

SYSTEMATIC REVIEW

Immunogenicity of COVID-19 vaccines in patients with hematologic malignancies: a systematic review and meta-analysis Clinical Trials & Observations

CLINICAL TRIALS AND OBSERVATIONS

Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy Clinical Trials & Observations

Hematologic malignancies magnify the effect of body mass index on insulin resistance in cancer survivors Clinical Trials & Observations

An international analysis evaluating frontline bendamustine with rituximab in extranodal marginal zone lymphoma Clinical Trials & Observations

Impact of comorbidity in older patients with peripheral T-cell lymphoma: an international retrospective analysis of 891 patients Clinical Trials & Observations

Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib Clinical Trials & Observations

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for higher-risk myelodysplastic syndromes Clinical Trials & Observations

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for older patients with AML Clinical Trials & Observations

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy Clinical Trials & Observations

Characterization of extramedullary disease in B-ALL and response to CAR T-cell therapy Clinical Trials & Observations

GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial Clinical Trials & Observations

LYMPHOID NEOPLASIA

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma Clinical Trials & Observations

MYELOID NEOPLASIA

Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses Clinical Trials & Observations

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

TRANSPLANTATION

The day 100 score predicts moderate to severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation Clinical Trials & Observations

Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation Clinical Trials & Observations

RESEARCH LETTER

NPM1 gene mutations can be confidently identified in blood DNA months before de novo AML onset Clinical Trials & Observations

COMMENTARY

Sustainability of low maternal mortality in pregnant women with SCD in a low-resource setting Global Advances

Does ruxolitinib really prolong survival in individuals with myelofibrosis? The never-ending story Clinical Trials & Observations

ERRATA

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ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia
Clinical Trials & Observations

COVID-19 and CAR T cells: a report on current challenges and future directions from the EPICOVIDEHA survey by EHA-IDWP
Clinical Trials & Observations

Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation
Clinical Trials & Observations

Immunogenicity of COVID-19 vaccines in patients with hematologic malignancies: a systematic review and meta-analysis
Clinical Trials & Observations

Optimal fludarabine lymphodepletion is associated with improved outcomes after CAR T-cell therapy
Clinical Trials & Observations

Hematologic malignancies magnify the effect of body mass index on insulin resistance in cancer survivors
Clinical Trials & Observations

An international analysis evaluating frontline bendamustine with rituximab in extranodal marginal zone lymphoma
Clinical Trials & Observations

Impact of comorbidity in older patients with peripheral T-cell lymphoma: an international retrospective analysis of 891 patients
Clinical Trials & Observations

Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib
Clinical Trials & Observations

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for higher-risk myelodysplastic syndromes
Clinical Trials & Observations

A randomized phase 2 trial of azacitidine with or without durvalumab as first-line therapy for older patients with AML
Clinical Trials & Observations

Severe cytokine release syndrome is associated with hematologic toxicity following CD19 CAR T-cell therapy
Clinical Trials & Observations

Characterization of extramedullary disease in B-ALL and response to CAR T-cell therapy
Clinical Trials & Observations

GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial
Clinical Trials & Observations

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma
Clinical Trials & Observations

Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses
Clinical Trials & Observations

The day 100 score predicts moderate to severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation
Clinical Trials & Observations

Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation
Clinical Trials & Observations

NPM1 gene mutations can be confidently identified in blood DNA months before de novo AML onset
Clinical Trials & Observations

Sustainability of low maternal mortality in pregnant women with SCD in a low-resource setting
Global Advances

Does ruxolitinib really prolong survival in individuals with myelofibrosis? The never-ending story
Clinical Trials & Observations