Skip to Main Content

Advertisement intended for health care professionals

Umbrella Alt Text
Cart
header search
Search
Skip Nav Destination

Issue Archive

Volume 4, Issue 13
July 14 2020
Issue Cover

Table of Contents

POINT-COUNTERPOINT

Allogeneic stem cell transplantation for high-risk acute leukemia and maintenance therapy: no time to waste
Bart L. Scott
View Articletitled, Allogeneic stem cell transplantation for high-risk acute leukemia and maintenance therapy: no time to waste
Maintenance therapy for high-risk acute leukemia after allogeneic hematopoietic cell transplantation: wait a minute
Robert J. Soiffer
View Articletitled, Maintenance therapy for high-risk acute leukemia after allogeneic hematopoietic cell transplantation: wait a minute

EXCEPTIONAL CASE REPORTS

First report of emicizumab use in a female patient with severe hemophilia A
Clinical Trials & Observations
Géraldine Verstraete,Catherine Lambert,Cedric Hermans
View Articletitled, First report of emicizumab use in a female patient with severe hemophilia A
Dasatinib induces a dramatic response in a child with refractory juvenile xanthogranuloma with a novel MRC1-PDGFRB fusion
Clinical Trials & Observations
Shaimaa S. Eissa,Michael R. Clay,Teresa Santiago,Gang Wu,Lu Wang,Barry L. Shulkin,Jennifer Picarsic,Kim E. Nichols,Patrick K. Campbell
View Articletitled, Dasatinib induces a dramatic response in a child with refractory juvenile xanthogranuloma with a novel <em>MRC1-PDGFRB</em> fusion
Targeted FGFR inhibition results in a durable remission in an FGFR1-driven myeloid neoplasm with eosinophilia
Clinical Trials & Observations
Monica Kasbekar,Valentina Nardi,Paola Dal Cin,Andrew M. Brunner,Meghan Burke,Yi-Bin Chen,Christine Connolly,Amir T. Fathi,Julia Foster,Molly Macrae,Steven L. McAfee,Kristin McGregor,Rupa Narayan,Aura Y. Ramos,Tina T. Som,Meghan Vartanian,Robb S. Friedman,Karim A. Benhadji,Gabriela S. Hobbs
View Articletitled, Targeted FGFR inhibition results in a durable remission in an FGFR1-driven myeloid neoplasm with eosinophilia

STIMULUS REPORTS

Venetoclax and hypomethylating agents (HMAs) induce high response rates in MDS, including patients after HMA therapy failure
Clinical Trials & Observations
Brian J. Ball,Christopher A. Famulare,Eytan M. Stein,Martin S. Tallman,Andriy Derkach,Mikhail Roshal,Saar I. Gill,Benjamin M. Manning,Jamie Koprivnikar,James McCloskey,Rebecca Testi,Thomas Prebet,Najla H. Al Ali,Eric Padron,David A. Sallman,Rami S. Komrokji,Aaron D. Goldberg
View Articletitled, Venetoclax and hypomethylating agents (HMAs) induce high response rates in MDS, including patients after HMA therapy failure
Supplemental data
Glasdegib as maintenance therapy for patients with AML and MDS patients at high risk for postallogeneic stem cell transplant relapse
Clinical Trials & Observations
Andrew Kent,Sumithira Vasu,Derek Schatz,Natalie Monson,Steven Devine,Clayton Smith,Jonathan A. Gutman,Daniel A. Pollyea
View Articletitled, Glasdegib as maintenance therapy for patients with AML and MDS patients at high risk for postallogeneic stem cell transplant relapse
Supplemental data

REVIEW ARTICLE

Low VWF: insights into pathogenesis, diagnosis, and clinical management
James S. O’Donnell
View Articletitled, Low VWF: insights into pathogenesis, diagnosis, and clinical management

SYSTEMATIC REVIEW

Genetic mutations and features of mantle cell lymphoma: a systematic review and meta-analysis
Holly A. Hill,Xinyue Qi,Preetesh Jain,Krystle Nomie,Yucai Wang,Shouhao Zhou,Michael L. Wang
View Articletitled, Genetic mutations and features of mantle cell lymphoma: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma
Clinical Trials & Observations
Chelsea C. Pinnix,Jillian R. Gunther,Bouthaina S. Dabaja,Paolo Strati,Penny Fang,Misha C. Hawkins,Sherry Adkins,Jason Westin,Sairah Ahmed,Luis Fayad,Hun Ju Lee,Ranjit Nair,Raphael E. Steiner,Swaminathan P. Iyer,M. Alma Rodriguez,Michael Wang,Christopher Flowers,Sattva S. Neelapu,Loretta J. Nastoupil
View Articletitled, Bridging therapy prior to axicabtagene ciloleucel for relapsed/refractory large B-cell lymphoma
DLBCL patients treated with CD19 CAR T cells experience a high burden of organ toxicities but low nonrelapse mortality
Clinical Trials & Observations
Kitsada Wudhikarn,Martina Pennisi,Marta Garcia-Recio,Jessica R. Flynn,Aishat Afuye,Mari Lynne Silverberg,Molly A. Maloy,Sean M. Devlin,Connie Lee Batlevi,Gunjan L. Shah,Michael Scordo,Maria Lia Palomba,Parastoo B. Dahi,Craig S. Sauter,Bianca D. Santomasso,Elena Mead,Miguel-Angel Perales
View Articletitled, DLBCL patients treated with CD19 CAR T cells experience a high burden of organ toxicities but low nonrelapse mortality
Supplemental data
Late molecular recurrences in patients with chronic myeloid leukemia experiencing treatment-free remission
Clinical Trials & Observations
Philippe Rousselot,Clémence Loiseau,Marc Delord,Jean Michel Cayuela,Marc Spentchian
View Articletitled, Late molecular recurrences in patients with chronic myeloid leukemia experiencing treatment-free remission
Supplemental data
Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: a phase 1b/2 dose-finding study
Clinical Trials & Observations
Vikas Gupta,Denise Wolleschak,Hans Hasselbalch,Alessandro Maria Vannucchi,Steffen Koschmieder,Francisco Cervantes,Yang Li,Tuochuan Dong,Monika Wroclawska,Savita Bharathy,Claire Harrison
View Articletitled, Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: a phase 1b/2 dose-finding study
Supplemental data
ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP
Clinical Trials & Observations
Linus A. Völker,Jessica Kaufeld,Wolfgang Miesbach,Sebastian Brähler,Martin Reinhardt,Lucas Kühne,Anja Mühlfeld,Adrian Schreiber,Jens Gaedeke,Markus Tölle,Wolfram J. Jabs,Fedai Özcan,Silke Markau,Matthias Girndt,Frederic Bauer,Timm H. Westhoff,Helmut Felten,Martin Hausberg,Marcus Brand,Jens Gerth,Markus Bieringer,Martin Bommer,Stefan Zschiedrich,Johanna Schneider,Saban Elitok,Alexander Gawlik,Anja Gäckler,Andreas Kribben,Vedat Schwenger,Ulf Schoenermarck,Maximilian Roeder,Jörg Radermacher,Jörn Bramstedt,Anke Morgner,Regina Herbst,Ana Harth,Sebastian A. Potthoff,Charis von Auer,Ralph Wendt,Hildegard Christ,Paul T. Brinkkoetter,Jan Menne
View Articletitled, ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP
Supplemental data
First-line non–anthracycline-based chemotherapy for extranodal nasal-type NK/T-cell lymphoma: a retrospective analysis from the CLCG
Clinical Trials & Observations
Shu-Nan Qi,Yong Yang,Yu-Qin Song,Ying Wang,Xia He,Chen Hu,Li-Ling Zhang,Gang Wu,Bao-Lin Qu,Li-Ting Qian,Xiao-Rong Hou,Fu-Quan Zhang,Xue-Ying Qiao,Hua Wang,Gao-Feng Li,Hui-Qiang Huang,Yu-Jing Zhang,Yuan Zhu,Jian-Zhong Cao,Jun-Xin Wu,Tao Wu,Su-Yu Zhu,Mei Shi,Li-Ming Xu,Zhi-Yong Yuan,Hang Su,Jun Zhu,Ye-Xiong Li
View Articletitled, First-line non–anthracycline-based chemotherapy for extranodal nasal-type NK/T-cell lymphoma: a retrospective analysis from the CLCG
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma
Poornima Ramkumar,Anthony B. Abarientos,Ruilin Tian,Meghan Seyler,Jaime T. Leong,Merissa Chen,Priya Choudhry,Torsten Hechler,Nina Shah,Sandy W. Wong,Thomas G. Martin, III,Jeffrey L. Wolf,Kole T. Roybal,Andreas Pahl,Jack Taunton,Arun P. Wiita,Martin Kampmann
View Articletitled, CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma
Supplemental data
The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells
Kamira Maharaj,John J. Powers,Alex Achille,Melanie Mediavilla-Varela,Wael Gamal,Karen L. Burger,Renee Fonseca,Kun Jiang,Hari P. Miskin,Dave Maryanski,Andrii Monastyrskyi,Derek R. Duckett,William R. Roush,John L. Cleveland,Eva Sahakian,Javier Pinilla-Ibarz
View Articletitled, The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells
Supplemental data

LYMPHOID NEOPLASIA

Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma
Christopher K. Rushton,Sarah E. Arthur,Miguel Alcaide,Matthew Cheung,Aixiang Jiang,Krysta M. Coyle,Kirstie L. S. Cleary,Nicole Thomas,Laura K. Hilton,Neil Michaud,Scott Daigle,Jordan Davidson,Kevin Bushell,Stephen Yu,Ryan N. Rys,Michael Jain,Lois Shepherd,Marco A. Marra,John Kuruvilla,Michael Crump,Koren Mann,Sarit Assouline,Joseph M. Connors,Christian Steidl,Mark S. Cragg,David W. Scott,Nathalie A. Johnson,Ryan D. Morin
View Articletitled, Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma
Supplemental data
Nationwide survey of systemic chronic active EBV infection in Japan in accordance with the new WHO classification
Clinical Trials & Observations
Ichiro Yonese,Chizuko Sakashita,Ken-Ichi Imadome,Tohru Kobayashi,Masahide Yamamoto,Akihisa Sawada,Yoshinori Ito,Noriko Fukuhara,Asao Hirose,Yusuke Takeda,Masanori Makita,Tomoyuki Endo,Shun-ichi Kimura,Masataka Ishimura,Osamu Miura,Shouichi Ohga,Hiroshi Kimura,Shigeyoshi Fujiwara,Ayako Arai
View Articletitled, Nationwide survey of systemic chronic active EBV infection in Japan in accordance with the new WHO classification
Supplemental data
ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia
Kayleigh M. Gallagher,Justine E. Roderick,Shi Hao Tan,Tze King Tan,Leonard Murphy,Jun Yu,Rui Li,Kevin W. O’Connor,Julie Zhu,Michael R. Green,Takaomi Sanda,Michelle A. Kelliher
View Articletitled, ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia
Supplemental data

MYELOID NEOPLASIA

Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro
Jan Habbel,Lucas Arnold,Yiyang Chen,Michael Möllmann,Kirsten Bruderek,Sven Brandau,Ulrich Dührsen,Maher Hanoun
View Articletitled, Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro
Supplemental data
Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML
Molly C. Kingsley,Hongbo M. Xie,Bo-Rui Chen,Simone S. Riedel,Taylor Pastuer,Madelyn K. Bollig,Tyler Shank,Clara Libbrecht,Sally P. Stabler,Aniruddha J. Deshpande,Andrew M. Intlekofer,Kathrin M. Bernt
View Articletitled, Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML
Supplemental data

PLATELETS AND THROMBOPOIESIS

Dominant role of αIIbβ3 in platelet interactions with cross-linked fibrin fragment D-dimer
Lorena Buitrago,Hina Zafar,Yixiao Zhang,Jihong Li,Thomas Walz,Barry S. Coller
View Articletitled, Dominant role of αIIbβ3 in platelet interactions with cross-linked fibrin fragment D-dimer
Platelet autoantibodies in the bone marrow of patients with immune thrombocytopenia
Sabrina Shrestha,Ishac Nazy,James W. Smith,John G. Kelton,Donald M. Arnold
View Articletitled, Platelet autoantibodies in the bone marrow of patients with immune thrombocytopenia
Supplemental data
Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity
A. J. Gerard Jansen,Thom Spaan,Hui Zhi Low,Daniele Di Iorio,Judith van den Brand,Malte Tieke,Arjan Barendrecht,Kerstin Rohn,Geert van Amerongen,Koert Stittelaar,Wolfgang Baumgärtner,Albert Osterhaus,Thijs Kuiken,Geert-Jan Boons,Jurriaan Huskens,Marianne Boes,Coen Maas,Erhard van der Vries
View Articletitled, Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity
Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation
Shauna L. French,Kirill R. Butov,Isabelle Allaeys,Jorge Canas,Golnaz Morad,Patricia Davenport,Audrée Laroche,Natalia M. Trubina,Joseph E. Italiano, Jr.,Marsha A. Moses,Martha Sola-Visner,Eric Boilard,Mikhail A. Panteleev,Kellie R. Machlus
View Articletitled, Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia
John Z. Cao,Hui Liu,Amittha Wickrema,Lucy A. Godley
View Articletitled, HIF-1 directly induces <em>TET3</em> expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia
Supplemental data

THROMBOSIS AND HEMOSTASIS

Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions
Magdolna Nagy,Gina Perrella,Amanda Dalby,M. Francisca Becerra,Lourdes Garcia Quintanilla,Jeremy A. Pike,Neil V. Morgan,Elizabeth E. Gardiner,Johan W. M. Heemskerk,Lorena Azócar,Juan Francisco Miquel,Diego Mezzano,Steve P. Watson
View Articletitled, Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions
Supplemental data
Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms
Ashley Cartwright,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Simon J. Webster,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Annika de Jong,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Richard J. Dirven,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Lisa D. S. Bloomer,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Ahlam M. AL-Buhairan,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Ulrich Budde,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Christer Halldén,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,David Habart,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Jenny Goudemand,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Ian R. Peake,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Jeroen C. J. Eikenboom,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Anne C. Goodeve,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups,Daniel J. Hampshire,on behalf of the European Group on von Willebrand Disease and Zimmerman Program for the Molecular and Clinical Biology of von Willebrand Disease Study Groups
View Articletitled, Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms
Supplemental data
Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura
Clinical Trials & Observations
Linus A. Völker,Jessica Kaufeld,Wolfgang Miesbach,Sebastian Brähler,Martin Reinhardt,Lucas Kühne,Anja Mühlfeld,Adrian Schreiber,Jens Gaedeke,Markus Tölle,Wolfram J. Jabs,Fedai Özcan,Silke Markau,Matthias Girndt,Frederic Bauer,Timm H. Westhoff,Helmut Felten,Martin Hausberg,Marcus Brand,Jens Gerth,Markus Bieringer,Martin Bommer,Stefan Zschiedrich,Johanna Schneider,Saban Elitok,Alexander Gawlik,Anja Gäckler,Andreas Kribben,Vedat Schwenger,Ulf Schoenermarck,Maximilian Roeder,Jörg Radermacher,Jörn Bramstedt,Anke Morgner,Regina Herbst,Ana Harth,Sebastian A. Potthoff,Charis von Auer,Ralph Wendt,Hildegard Christ,Paul T. Brinkkoetter,Jan Menne
View Articletitled, Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura
Supplemental data
Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets
Jiaojiao Sun,Desheng Xiao,Yuan Ni,Tianlong Zhang,Zhongyuan Cao,Zhou Xu,Huong Nguyen,Jun Zhang,Gilbert C. White,Jianping Ding,Yan-Qing Ma,Zhen Xu
View Articletitled, Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets
Supplemental data
The spectrum and severity of bleeding in adolescents with low von Willebrand factor–associated heavy menstrual bleeding
Clinical Trials & Observations
Lakshmi Srivaths,Charles G. Minard,Sarah H. O’Brien,Allison P. Wheeler,Eric Mullins,Mukta Sharma,Robert Sidonio,Shilpa Jain,Ayesha Zia,Margaret V. Ragni,Roshni Kulkarni,Jennifer E. Dietrich,Peter A. Kouides
View Articletitled, The spectrum and severity of bleeding in adolescents with low von Willebrand factor–associated heavy menstrual bleeding

TRANSPLANTATION

Patterns of salivary microbiota injury and oral mucositis in recipients of allogeneic hematopoietic stem cell transplantation
Clinical Trials & Observations
Roni Shouval,Adi Eshel,Bar Dubovski,Amir A. Kuperman,Ivetta Danylesko,Joshua A. Fein,Shalev Fried,Mika Geva,Elizaveta Kouniavski,Hadar Neuman,Ayelet Armon-Omer,Radi Shahien,Efrat Muller,Cecilia Noecker,Elhanan Borenstein,Yoram Louzoun,Arnon Nagler,Omry Koren
View Articletitled, Patterns of salivary microbiota injury and oral mucositis in recipients of allogeneic hematopoietic stem cell transplantation
Supplemental data
Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders
Clinical Trials & Observations
Mark T. Vander Lugt,Xiaohua Chen,Maria L. Escolar,Beth A. Carella,Jessie L. Barnum,Randy M. Windreich,Memphis J. Hill,Michelle Poe,Rebecca A. Marsh,Heather Stanczak,Elizabeth O. Stenger,Paul Szabolcs
View Articletitled, Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders
Supplemental data
Risk factors and appropriate therapeutic strategies for thrombotic microangiopathy after allogeneic HSCT
Hiroyuki Matsui,Yasuyuki Arai,Hiroharu Imoto,Takaya Mitsuyoshi,Naoki Tamura,Tadakazu Kondo,Junya Kanda,Takayuki Ishikawa,Kazunori Imada,Yasunori Ueda,Yusuke Toda,Naoyuki Anzai,Kazuhiro Yago,Masaharu Nohgawa,Akihito Yonezawa,Hiroko Tsunemine,Mitsuru Itoh,Kazuyo Yamamoto,Masaaki Tsuji,Toshinori Moriguchi,Akifumi Takaori-Kondo,Kyoto Stem Cell Transplantation Group (KSCTG)
View Articletitled, Risk factors and appropriate therapeutic strategies for thrombotic microangiopathy after allogeneic HSCT
Supplemental data
Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a CIBMTR report
Clinical Trials & Observations
Zheng Zhou,Rajneesh Nath,Jan Cerny,Hai-Lin Wang,Mei-Jie Zhang,Hisham Abdel-Azim,Vaibhav Agrawal,Gulrayz Ahmed,A. Samer Al-Homsi,Mahmoud Aljurf,Hassan B. Alkhateeb,Amer Assal,Ulrike Bacher,Ashish Bajel,Qaiser Bashir,Minocher Battiwalla,Vijaya Raj Bhatt,Michael Byrne,Jean-Yves Cahn,Mitchell Cairo,Hannah Choe,Edward Copelan,Corey Cutler,Moussab B. Damlaj,Zachariah DeFilipp,Marcos De Lima,Miguel Angel Diaz,Nosha Farhadfar,James Foran,César O. Freytes,Aaron T. Gerds,Usama Gergis,Michael R. Grunwald,Zartash Gul,Mehdi Hamadani,Shahrukh Hashmi,Mark Hertzberg,Gerhard C. Hildebrandt,Nasheed Hossain,Yoshihiro Inamoto,Luis Isola,Tania Jain,Rammurti T. Kamble,Muhammad Waqas Khan,Mohamed A. Kharfan-Dabaja,Partow Kebriaei,Natasha Kekre,Nandita Khera,Hillard M. Lazarus,Jane L. Liesveld,Mark Litzow,Hongtao Liu,David I. Marks,Rodrigo Martino,Vikram Mathews,Asmita Mishra,Hemant S. Murthy,Arnon Nagler,Ryotaro Nakamura,Sunita Nathan,Taiga Nishihori,Rebecca Olin,Richard F. Olsson,Neil Palmisiano,Sagar S. Patel,Mrinal M. Patnaik,Attaphol Pawarode,Miguel-Angel Perales,Ioannis Politikos,Uday Popat,David Rizzieri,Brenda M. Sandmaier,Bipin N. Savani,Sachiko Seo,Nirav N. Shah,Geoffrey L. Uy,David Valcárcel,Leo F. Verdonck,Edmund K. Waller,Youjin Wang,Daniel Weisdorf,Baldeep Wirk,Eric Wong,Jean A. Yared,Wael Saber
View Articletitled, Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a CIBMTR report
Supplemental data

VASCULAR BIOLOGY

Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria
Christopher A. Moxon,Yasir Alhamdi,Janet Storm,Julien M. H. Toh,Dagmara McGuinness,Joo Yeon Ko,George Murphy,Steven Lane,Terrie E. Taylor,Karl B. Seydel,Sam Kampondeni,Michael Potchen,James S. O’Donnell,Niamh O’Regan,Guozheng Wang,Guillermo García-Cardeña,Malcolm Molyneux,Alister G. Craig,Simon T. Abrams,Cheng-Hock Toh
View Articletitled, Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria
Supplemental data

COMMENTARIES

Navigating the narrow bridge to CAR T-cell therapy
Clinical Trials & Observations
Joanna C. Yang,John P. Plastaras
View Articletitled, Navigating the narrow bridge to CAR T-cell therapy
Ensuring continuity of care of hematologic patients during COVID-19 pandemic in a tertiary hospital in Lombardy (Italy)
Bruno Fattizzo,Juri Alessandro Giannotta,Wilma Barcellini,Maria Chiara Barbanti,Cristina Bucelli,Ramona Cassin,Daniele Cattaneo,Francesca Cavallaro,Valeria Ferla,Nicola Stefano Fracchiolla,Alessandra Freyrie,Giulia Galassi,Maria Cecilia Goldaniga,Federica Irene Grifoni,Alessandra Iurlo,Giancarlo Mangiameli,Veronica Mattiello,Mario Meli,Antonino Neri,Alessandro Noto,Francesco Onida,Laura Ottani,Raffaella Pasquale,Loredana Pettine,Alessandra Pompa,Gianluigi Reda,Francesca Gaia Rossi,Giorgia Natascia Saporiti,Mariarita Sciumè,Elena Tagliaferri,Luca Baldini
View Articletitled, Ensuring continuity of care of hematologic patients during COVID-19 pandemic in a tertiary hospital in Lombardy (Italy)
Clinical efficacy of anakinra to mitigate CAR T-cell therapy–associated toxicity in large B-cell lymphoma
Paolo Strati,Sairah Ahmed,Partow Kebriaei,Loretta J. Nastoupil,Catherine M. Claussen,Grace Watson,Sandra B. Horowitz,Anne Rain T. Brown,Bryan Do,Maria A. Rodriguez,Ranjit Nair,Elizabeth J. Shpall,Michael R. Green,Sattva S. Neelapu,Jason R. Westin
View Articletitled, Clinical efficacy of anakinra to mitigate CAR T-cell therapy–associated toxicity in large B-cell lymphoma

ERRATUM

Ritz C, Meng W, Stanley NL, et al. Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes. Blood Adv. 2020;4(7):1378-1382.
View Articletitled, Ritz C, Meng W, Stanley NL, et al. Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8<sup>+</sup> lymphocytes. <em>Blood Adv.</em> 2020;4(7):1378-1382.
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Confocal fluorescence microscopic image of a representative megakaryocyte after 1 hour of coculture with platelet-derived extracellular vesicles (PEVs) labeled with MitoTracker Red. The image shows accumulation of PEV-derived mitochondria (red) within the megakaryocyte (nucleus stained with Hoechst 33342, blue). See the article by French et al.

  • PDF Icon PDF LinkFront Matter
  • PDF Icon PDF LinkEditorial Board
All Issues

Advertisement intended for health care professionals

Predicting CAR T-cell toxicity: insurance for CAR crashes
Optical genome mapping identified deletions, inversions, and insertions in hemophilia
Relapse-free survival is progressively shortened in a subset of Black patients with immune-mediated TTP treated in the rituximab era
Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response
Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs

Advertisement intended for health care professionals

Advertisement intended for health care professionals

  • American Society of Hematology
  • 2021 L Street NW, Suite 900
  • Washington, DC 20036
  • TEL +1 202-776-0544
  • FAX +1 202-776-0545

ASH Publications

American Society of Hematology

Copyright 2024 by American Society of Hematology
 
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal

Advertisement intended for health care professionals