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BLOOD ADVANCES TALK

POINT-COUNTERPOINT

EXCEPTIONAL CASE REPORT

STIMULUS REPORT

IMMUNOBIOLOGY

LYMPHOID NEOPLASIA

  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    In silico PyMOL modeling showing a representation of the normal nonactivated αIIb (purple) and β3 (green) transmembrane and cytoplasmic tail segments, highlighting amino acids engaged in the inner membrane association clasp. A single-amino-acid β3 Leu718 deletion detected in a patient with inherited macrothrombocytopenia and defective platelet aggregation changes the synchronization of the αIIbβ3 cytoplasmic tails and weakens the clasp. See the article by Nurden et al.

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