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Issue Archive

Volume 1, Issue 1
November 29 2016
Issue Cover

Table of Contents

EDITORIAL

Welcome to Blood Advances
Robert S. Negrin
View Articletitled, Welcome to <em>Blood Advances</em>

BLOOD ADVANCES TALKS

New developments in the management of sickle cell disease
Alexis A. Thompson
View Articletitled, New developments in the management of sickle cell disease
Supplemental data
Should we avoid heparin to eliminate HIT?
Gowthami Morey Arepally
View Articletitled, Should we avoid heparin to eliminate HIT?
Supplemental data

POINT-COUNTERPOINT

Platelets and hemostasis: a new perspective on an old subject
Lawrence F. Brass,Scott L. Diamond,Timothy J. Stalker
View Articletitled, Platelets and hemostasis: a new perspective on an old subject
Platelets as immune-sensing cells
Rick Kapur,John W. Semple
View Articletitled, Platelets as immune-sensing cells

STIMULUS REPORT

YY1 controls Eμ-3′RR DNA loop formation and immunoglobulin heavy chain class switch recombination
Parul Mehra,Tatiana Gerasimova,Arindam Basu,Vibha Jha,Anupam Banerjee,Vishal Sindhava,Falon Gray,Corbett T. Berry,Ranjan Sen,Michael L. Atchison
View Articletitled, YY1 controls Eμ-3′RR DNA loop formation and immunoglobulin heavy chain class switch recombination
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Targeted deep sequencing in polycythemia vera and essential thrombocythemia
Clinical Trials & Observations
Ayalew Tefferi,Terra L. Lasho,Paola Guglielmelli,Christy M. Finke,Giada Rotunno,Yoseph Elala,Annalisa Pacilli,Curtis A. Hanson,Alessandro Pancrazzi,Rhett P. Ketterling,Carmela Mannarelli,Daniela Barraco,Tiziana Fanelli,Animesh Pardanani,Naseema Gangat,Alessandro M. Vannucchi
View Articletitled, Targeted deep sequencing in polycythemia vera and essential thrombocythemia
Supplemental data
Bortezomib-based antibody depletion for refractory autoimmune hematological diseases
Clinical Trials & Observations
Sumita Ratnasingam,Patricia A. Walker,Huy Tran,Zane S. Kaplan,James D. McFadyen,Huyen Tran,Tse-Chieh Teh,Shaun Fleming,John V. Catalano,Sanjeev D. Chunilal,Anna Johnston,Stephen S. Opat,Jake Shortt
View Articletitled, Bortezomib-based antibody depletion for refractory autoimmune hematological diseases

HEMATOPOIESIS AND STEM CELLS

Extended clinical and genetic spectrum associated with biallelic RTEL1 mutations
Fabien Touzot,Laetitia Kermasson,Laurent Jullien,Despina Moshous,Christelle Ménard,Aydan Ikincioğullari,Figen Doğu,Sinan Sari,Vannina Giacobbi-Milet,Amos Etzioni,Jean Soulier,Arturo Londono-Vallejo,Alain Fischer,Isabelle Callebaut,Jean-Pierre de Villartay,Thierry Leblanc,Caroline Kannengiesser,Patrick Revy
View Articletitled, Extended clinical and genetic spectrum associated with biallelic <em>RTEL1</em> mutations
Supplemental data

LYMPHOID NEOPLASIA

Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment
Sara Serra,Tiziana Vaisitti,Valentina Audrito,Cinzia Bologna,Roberta Buonincontri,Shih-Shih Chen,Francesca Arruga,Davide Brusa,Marta Coscia,Ozren Jaksic,Giorgio Inghirami,Davide Rossi,Richard R. Furman,Simon C. Robson,Gianluca Gaidano,Nicholas Chiorazzi,Silvia Deaglio
View Articletitled, Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment
Supplemental data

PLATELETS AND THROMBOPOIESIS

Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia
Douglas B. Cines,Serge V. Yarovoi,Sergei V. Zaitsev,Tatiana Lebedeva,Lubica Rauova,Mortimer Poncz,Gowthami M. Arepally,Sanjay Khandelwal,Victoria Stepanova,Ann H. Rux,Adam Cuker,Cecilia Guo,Linnette Mae Ocariza,Richard J. Travers,Stephanie A. Smith,Hugh Kim,James H. Morrissey,Edward M. Conway
View Articletitled, Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia
Supplemental data

THROMBOSIS AND HEMOSTASIS

Therapeutic efficacy of the platelet glycoprotein Ib antagonist anfibatide in murine models of thrombotic thrombocytopenic purpura
Liang Zheng,Yingying Mao,Mohammad S. Abdelgawwad,Nicole K. Kocher,Mandy Li,Xiangrong Dai,Benjamin Li,X. Long Zheng
View Articletitled, Therapeutic efficacy of the platelet glycoprotein Ib antagonist anfibatide in murine models of thrombotic thrombocytopenic purpura
Supplemental data

GLOBAL ADVANCES

Targetable subsets of non-Hodgkin lymphoma in Malawi define therapeutic opportunities
Global Advances
Elizabeth A. Morgan,M. Patrick Sweeney,Tamiwe Tomoka,Nadja Kopp,Daniel Gusenleitner,Robert A. Redd,Christopher D. Carey,Leo Masamba,Steve Kamiza,Geraldine S. Pinkus,Donna S. Neuberg,Scott J. Rodig,Danny A. Milner, Jr,David M. Weinstock
View Articletitled, Targetable subsets of non-Hodgkin lymphoma in Malawi define therapeutic opportunities
Supplemental data
Hemoglobin variants identified in the Uganda Sickle Surveillance Study
Global Advances
Beverly A. Schaefer,Charles Kiyaga,Thad A. Howard,Grace Ndeezi,Arielle G. Hernandez,Isaac Ssewanyana,Mary C. Paniagua,Christopher M. Ndugwa,Jane R. Aceng,Russell E. Ware
View Articletitled, Hemoglobin variants identified in the Uganda Sickle Surveillance Study
Supplemental data

COMMENTARY

Obesity and neoplasms of lymphohematopoietic cells
Marshall A. Lichtman
View Articletitled, Obesity and neoplasms of lymphohematopoietic cells
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    Confocal microscopy analysis of nurse-like cells (NLCs) differentiated from peripheral blood mononuclear cells purified from a chronic lymphocytic leukemia patient. NLCs were stained with the lineage-specific marker CD68 (green) and counterstained with phalloidin (red) and 4′,6-diamidino-2-phenylindole (blue). Original magnification ×63. Adapted by Somersault18:24 from Figure 5A of the article by Serra et al beginning on page 47.

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