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Search Results for sickle cell disease
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sickle cell disease
Elliott P. Vichinsky, Lori A. Styles, Linda H. Colangelo, Elizabeth C. Wright, Oswaldo Castro, Bruce Nickerson, the Cooperative Study of Sickle Cell Disease
Blood (1997) 89 (5): 1787–1792.
...Elliott P. Vichinsky; Lori A. Styles; Linda H. Colangelo; Elizabeth C. Wright; Oswaldo Castro; Bruce Nickerson; the Cooperative Study of Sickle Cell Disease Acute chest syndrome (ACS) is an important cause of morbidity and mortality in sickle cell disease (SCD). Previous studies reported...
Mark C. Walters, Rainer Storb, Melinda Patience, Wendy Leisenring, Terri Taylor, Jean E. Sanders, George E. Buchanan, Zora R. Rogers, Patricia Dinndorf, Sally C. Davies, Irene A. G. Roberts, Rosarita Dickerhoff, Andrew M. Yeager, Lewis Hsu, Joanne Kurtzberg, Kwaku Ohene-Frempong, Nancy Bunin, Francoise Bernaudin, Wing-Yen Wong, J. Paul Scott, David Margolis, Elliott Vichinsky, Donna A. Wall, Allen S. Wayne, Charles Pegelow, Rupa Redding-Lallinger, Joseph Wiley, Martin Klemperer, William C. Mentzer, Franklin O. Smith, Keith M. Sullivan
Blood (2000) 95 (6): 1918–1924.
...; Francoise Bernaudin; Wing-Yen Wong; J. Paul Scott; David Margolis; Elliott Vichinsky; Donna A. Wall; Allen S. Wayne; Charles Pegelow; Rupa Redding-Lallinger; Joseph Wiley; Martin Klemperer; William C. Mentzer; Franklin O. Smith; Keith M. Sullivan Fifty children who had symptomatic sickle cell disease...
Dipti Gupta, Sarah Sturtevant, BSc, Benjamin Vieira, BS, Yukio Nakamura, MD PhD, Sriram Krishnamoorthy, PhD, Melanie Demers, PhD
Blood (2019) 134 (Supplement_1): 3559.
...Dipti Gupta; Sarah Sturtevant, BSc; Benjamin Vieira, BS; Yukio Nakamura, MD PhD; Sriram Krishnamoorthy, PhD; Melanie Demers, PhD Sickle cell disease (SCD) is a genetic disorder caused by a missense mutation in the beta-globin gene [Glu6Val] resulting in the formation of HbS (sickle hemoglobin). HbS...
Lanetta Bronté-Hall, MPH, MSPH, MD, Matthew Parkin, Courtney Green, Elsa Tchouambou, DO, Lynn Huynh, MPH, MBA, DrPH, Charu Puri-Sharma, MS, Rose Chang, MSPH, MS, ScD, Anjulika Chawla, MD, James Signorovitch, PhD, Gershwin Theophilus Blyden, MD
Blood (2019) 134 (Supplement_1): 5856.
...Lanetta Bronté-Hall, MPH, MSPH, MD; Matthew Parkin; Courtney Green; Elsa Tchouambou, DO; Lynn Huynh, MPH, MBA, DrPH; Charu Puri-Sharma, MS; Rose Chang, MSPH, MS, ScD; Anjulika Chawla, MD; James Signorovitch, PhD; Gershwin Theophilus Blyden, MD Background Sickle cell disease (SCD) is a progressively...
Blood (2018) 132 (Supplement 1): 5805.
...Stacy Desine, BA; Brittany Hollister, PhD; Anitra Persaud, BA; Vence L. Bonham, J.D. Introduction: One of the first therapeutic targets of CRISPR genome editing will likely be sickle cell disease (SCD), the most commonly inherited blood disorder in the U.S.SCD affects 100,000 individuals in the U.S...
Patrick B. Walter, PhD, David W. Killilea, PhD, Ellen B. Fung, PhD, Annie Lui, BS, Jacqueline Madden, PNP, John Porter, MD, Patricia Evans, PhD, Bruce N. Ames, PhD, Elliott Vichinsky, MD, Paul Harmatz, MD
Blood (2006) 108 (11): 1233.
...Patrick B. Walter, PhD; David W. Killilea, PhD; Ellen B. Fung, PhD; Annie Lui, BS; Jacqueline Madden, PNP; John Porter, MD; Patricia Evans, PhD; Bruce N. Ames, PhD; Elliott Vichinsky, MD; Paul Harmatz, MD Sickle cell disease (SCD) is a hemoglobinopathy characterized by micro-vascular hypoxia...
Baba Inusa, MD MRCP, Jo Howard, MBBCh, Subarna Chakravorty, MBBS, PhD FRCPath, MRCP, Maria Pelidis, MD, Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP, Fenella J Kirkham, MD
Blood (2017) 130 (Supplement 1): 3537.
...Baba Inusa, MD MRCP; Jo Howard, MBBCh; Subarna Chakravorty, MBBS, PhD FRCPath, MRCP; Maria Pelidis, MD; Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP; Fenella J Kirkham, MD Abstract Background: In addition to pain, sickle cell anaemia (HbSS) complications include neurocognitive difficulties...
April E Slee, Jamie M Kawadler, PhD, Melanie Koelbel, MSc, Hanne Stotesbury, MSc, David C Rees, MD, Maria Pelidis, MD, Jo Howard, MBBCh, Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP, Simon Skene, PhD, Sahota Sati, BSc, Carol Nwosu, BSc, Maureen Gwam, BSc, Dawn Saunders, MD, Johanna C Gavlak, PhD, Gupta Atul, MD, Simrat Sarkaria, Christina Liossi, PhD, Fenella J Kirkham, MD, Baba Inusa, MD MRCP
Blood (2017) 130 (Supplement 1): 3556.
..., PhD; Gupta Atul, MD; Simrat Sarkaria; Christina Liossi, PhD; Fenella J Kirkham, MD; Baba Inusa, MD MRCP Background: Complications in sickle cell anemia (SCA, HbSS) include neurocognitive difficulties in attention and processing speed associated with low daytime and night-time oxygen saturation...
Samuel A Oppong, MD, Edeghonghon Olayemi, MBBS, MSc, Yvonne Adomakoh, MBBS, Eugenia Vicky Asare, MBChB, BSc, Enoch Mensah, HND, Alim Swarray-Deen, MD, Yvonne Osei-Bonsu, Dip(PH), Selina Crabbe, Dip(PH), Latif Musah, BSc, Theodore Boafor, MBChB, Brittany Covert, MPH, CCRP, Adetola A. Kassim, MD MS, Andra H. James, MDMPH, Mark Rodeghier, PhD, Michael R. DeBaun, MD MPH
Blood (2017) 130 (Supplement 1): 616.
...; Andra H. James, MDMPH; Mark Rodeghier, PhD; Michael R. DeBaun, MD MPH Background: Sickle cell disease (SCD) is a major public health problem in Sub-Saharan Africa, which is home to about 70% of the affected individuals worldwide. Pregnancy is an emerging life-threatening complication of SCD with high...
Jean-Antoine Ribeil, MD, PhD, Patrícia Santos Ressende Cardoso, MD, Aurelie Stanislas, ARC, Vanessa Maria Fenelon Costa, MD, Benjamin Deloison, MD, Milza Cintra Januario, MD, Caroline Charlier, MD, PhD, Laia Batlle, MD, Yves Ville, MD, Yves Dumez, PhD, Frederic Galacteros, MD PhD, Olivier Lortholary, MD, PhD, Alexandra Benachi, MD, PhD, Jean-Marc Treluyer, PhD, Annalisa Ruggeri, MD, Marcos Borato Viana, MD, Eliane Gluckman, MD, PhD, Vanderson Rocha, MD, PhD, Marina Cavazzana-Calvo, MD, PhD, Regina Amélia Lopes Pessoa de Aguiar, PhD, MD
Blood (2012) 120 (21): 3215.
... Cell Disease Observatory (ISCDO) is an international group, established in 2011, including representatives from countries where sickle cell disease (SCD) is highly prevalent, in order to collect and share information of SCD patient's to improve patients care and quality of life, to define common...
Najibah Aliyu Galadanci, MBBS, Wayne Liang, MD, Muktar Aliyu, MD, DrPH, MPH, Binta Wudil Jibir, MBBS, MSc, Ibraheem Karaye, MBBS, Baba PD Inusa, MD, FRCPCH, Sten Vermund, MD, PhD, Michael R. DeBaun, MD, MPH
Blood (2012) 120 (21): 4760.
... with sickle cell disease (SCD) in the world. Approximately 150,000 children are born with SCD each year (incident cases) in Nigeria, compared to a total of approximately 100,000 children and adults living with SCD in the United States (prevalent cases). Pulmonary complications, including asthma and asthma...
Jo Howard, MB, BChir, MRCP, FRCPath, Moira Malfroy, RN, Llewelyn Charlotte, PhD, Louise Choo, PhD, David Rees, FRCPath, Isabeau Walker, FRCA, Tony Johnson, PhD, Louise Tillyer, FRCPath, Karin Fijnvandraat, MD, PhD, Melanie Kirby-Allen, MD, Renate Hodge, MSc, Shilpi Purohit, Sally C. Davies, FRCP, FMedSci, Lorna M Williamson, FRCPath
Blood (2011) 118 (21): 9.
..., FMedSci; Lorna M Williamson, FRCPath Abstract 9 Introduction: The rate of complications after surgery is increased in patients with Sickle Cell Disease (SCD) and pre-operative blood transfusion has historically been used to decrease this risk. Observational studies and one limited Randomised Controlled...
Blood (2011) 118 (21): 4848.
...Dalal H. Mulla-Ali, MD; Kevin H.M. Kuo, MD; Mathew Sermer, MD; Anne Mcleod, MD Abstract 4848 Introduction: Patients with sickle cell disease (SCD) have worse maternal and fetal outcomes compared to the general population, and experience antepartum complications unique to SCD patients, including...
Blood (2009) 114 (22): 4625.
...Ariel Koren, MD; Daniel Fink; Osnat Admoni; Yardena Tennenbaum-Rakover; Carina Levin Abstract 4625 BACKGROUND Blood transfusions are the standard of care in β thalassemia and transfusions are also indicated in Sickle Cell Disease (SCD) patients with hypersplenism, recurrent vaso-occlusive crises...
Blood (2009) 114 (22): 4607.
...Raymond U. Osarogiagbon, MBBS; Syed N Haider, MD; Jun Tang, MS, Phd Abstract 4607 Introduction The high mortality risk that sickle cell disease (SCD) patients experience from infancy is cumulative through adulthood, largely because of the effect of cumulative end organ damage, which is a more...
A Randomized Trial of the Safety and Benefit of Transfusion Vs. Standard Care In the Prevention of Sickle Cell-Related Complications In Adults: a Preliminary Report From the Phase II NHLBI Comprehensive Sickle Cell Centers (CSCC) Study of Neuropsychological Dysfunction and Neuroimaging Abnormalities In Neurologically Intact Adult Patients with Sickle Cell Disease
Elliott Vichinsky, MD, Lynne Neumayr, MD, Jeffrey I Gold, PhD, Michael W Weiner, MD, Jeffrey Kasten, Diana Truran, Cathie Snyder, Karen Kesler, PhD, Atif Mahmoud Hussein, MD, FACP, Thomas J. Harrington, MD, Lillian McMahon, MD, Victor R. Gordeuk, MD, Abdullah Kutlar, MD, Eugene P. Orringer, MD, Laura M. De Castro, MD, Joshua Field, MD, Paul S. Swerdlow, MD, Joel David Bessman, MD, Richard Snyder, MD, John J. Strouse, MD, PhD, F. Daniel Armstrong, PhD
Blood (2010) 116 (21): 3221.
...-related adverse events, and decrease in hospitalizations. Increase in ferritin is an expected outcome in transfused patients since chelation was not a part of this transfusion protocol. On completion of the study, the potential benefits of transfusion therapy on sickle cell disease morbidity including...
Emily Riehm Meier, MD MSHS, Allistair Abraham, MD, Alexander I. Ngwube, MD, Isaac Janson, PhD, Gregory M.T. Guilcher, MD, John T. Horan, MDMPH, Kimberly A. Kasow, DO
Blood (2019) 134 (Supplement_1): 2164.
...Emily Riehm Meier, MD MSHS; Allistair Abraham, MD; Alexander I. Ngwube, MD; Isaac Janson, PhD; Gregory M.T. Guilcher, MD; John T. Horan, MDMPH; Kimberly A. Kasow, DO Background Hematopoietic stem cell transplantation (HSCT) provides a curative therapy for children severely affected by sickle cell...
Amer Assal, MD, Diane George, MD, Monica Bhatia, MD, Christian Gordillo, BS, Nicole Howard, BS, Ran Reshef, MD MSc, Markus Y Mapara, MD PhD
Blood (2018) 132 (Supplement 1): 5713.
...Amer Assal, MD; Diane George, MD; Monica Bhatia, MD; Christian Gordillo, BS; Nicole Howard, BS; Ran Reshef, MD MSc; Markus Y Mapara, MD PhD Introduction: Sickle cell disease (SCD) affects 300,000 annual births globally, and about 100,000 individuals in the United States. Allogeneic hematopoietic...
Allistair Abraham, MD, Elizabeth Stenger, MD, Curtis D Travers, MPH, Robert Nickel, MDMSc, Hemalatha G. Rangarajan, MD, Jennifer Krajewski, MD, Sonali Chaudhury, MBBS,MD, Kimberly A. Kasow, DO, Troy C. Quigg, DO, Alexander I. Ngwube, MD, Jennifer Jaroscak, MD, Gregory M Guilcher, MDBSc,FRCPC, Shalini Shenoy, MD, John T Horan, MD
Blood (2017) 130 (Supplement 1): 3535.
...; Shalini Shenoy, MD; John T Horan, MD Background: Myeloablative HLA-matched sibling donor hematopoietic cell transplantation (HCT) is highly curative for children and young adults with sickle cell disease (SCD). The most common regimen used worldwide has been Busulfan, Cyclophosphamide and anti-thymocyte...
John Chinawaeze Aneke, MBBS, Aliraza Rajabali, Nafanta Fadiga, Stéphanie Forté, MD MSc, FRCPC, George A. Tomlinson, PhD BSc, MSc, Christine M. Cserti-Gazdewich, BSc, MD FRCPC, Christopher J. Patriquin, MDFRCPC,MSc, Richard Ward, MSc, MRCP, FRCPath, Jacob Pendergrast, MDFRCPC, David Barth, MD FRCPC, Kevin H. M. Kuo, MDMSc,FRCPC
Blood (2019) 134 (Supplement_1): 2170.
...; Kevin H. M. Kuo, MDMSc,FRCPC Rate of Sickle Hemoglobin Recovery in Sickle Cell Disease Patients Undergoing Red Blood Cell (RBC) Exchange Transfusion is Associated with Age of Patients and Number of RBC Units Transfused Introduction : Automated and manual red blood cell exchange (RBCX) transfusions...