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Journal Articles

17( R )-Resolvin D1 protects against sickle cell–related inflammatory cardiomyopathy in humanized mice

Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Matte, Maria Monti, Flora Cozzolino, Manuela Iezzi, Martina Ceci, Alessandra Ghigo, Emanuela Tolosano, Angela Siciliano, Jacopo Ceolan, Veronica Riccardi, Elisa Gremese, Carlo Brugnara, Lucia De Franceschi

Blood (2025) 145 (17): 1915–1928.

https://doi.org/10.1182/blood.2024024768

Published: 2025

Includes: Supplemental data

Journal Articles

Sickle cell trait does not cause “sickle cell crisis” leading to exertion-related death: a systematic review

Lachelle D. Weeks, Allecia M. Wilson, Rakhi P. Naik, Yvonne Efebera, M. Hassan Murad, Anjlee Mahajan, Patrick T. McGann, Madeleine Verhovsek, Angela C. Weyand, Ahmar U. Zaidi, Michael R. DeBaun, Chancellor Donald, Roger A. Mitchell

Blood (2025) 145 (13): 1345–1352.

https://doi.org/10.1182/blood.2024026899

Published: 2025

Includes: Supplemental data

Journal Articles

How I treat sickle cell disease with gene therapy

Akshay Sharma

Blood (2024) 144 (26): 2693–2705.

https://doi.org/10.1182/blood.2024024519

Published: 2024

Journal Articles

TR4 and BCL11A repress γ-globin transcription via independent mechanisms

Yu Wang, Greggory Myers, Lei Yu, Kaiwen Deng, Ginette Balbin-Cuesta, Sharon A. Singh, Yuanfang Guan, Rami Khoriaty, James Douglas Engel

Blood (2024) 144 (26): 2762–2772.

https://doi.org/10.1182/blood.2024024599

Published: 2024

Includes: Supplemental data

Journal Articles

Genotyped RhD + red cells for D-positive patients with sickle cell disease with conventional RHD and unexpected anti-D

Stella T. Chou, Julia Mewha, David F. Friedman, Victoria Lazariu, Shaimaa Makrm, Gorka Ochoa, Sunitha Vege, Connie M. Westhoff

Blood (2024) 144 (19): 2045–2049.

https://doi.org/10.1182/blood.2024025602

Published: 2024

Includes: Supplemental data

Journal Articles

Less-deformable erythrocyte subpopulations biomechanically induce endothelial inflammation in sickle cell disease

Christina Caruso, Xiaopo Cheng, Marina E. Michaud, Hannah M. Szafraniec, Beena E. Thomas, Meredith E. Fay, Robert G. Mannino, Xiao Zhang, Yumiko Sakurai, Wei Li, David R. Myers, Clinton H. Joiner, David K. Wood, Manoj Bhasin, Michael D. Graham, Wilbur A. Lam

Blood (2024) 144 (19): 2050–2062.

https://doi.org/10.1182/blood.2024024608

Published: 2024

Includes: Supplemental data

Journal Articles

Significant pituitary siderosis is common in transfusion-dependent sickle cell disease

Akhila Vadivelan, Eamon K. Doyle, Susan Carson, Christopher Denton, Saranya Veluswamy, Thomas Hofstra, Thomas D. Coates, John Wood

Blood (2024) 144 (13): 1457–1459.

https://doi.org/10.1182/blood.2024025462

Published: 2024

Journal Articles

Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease

Akshay Sharma, Subodh Selukar, Yu Bi, Anthony Merlocco, Cara E. Morin, Chris Goode, Parul Rai, Jeffrey A. Towbin, Jane S. Hankins, Stephen Gottschalk, Brandon Triplett, Jason N. Johnson

Blood (2024) 144 (6): 672–675.

https://doi.org/10.1182/blood.2023023028

Published: 2024

Includes: Supplemental data

Journal Articles

Heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice

Qiyang Chen, Rimi Hazra, Danielle Crosby, Diane Lenhart, Shane C. Lenhart, Paritosh Mondal, Yingze Zhang, Seyed M. Nouraie, Roderick J. Tan, Charles T. Esmon, L. Vijay Mohan Rao, Kang Kim, Samit Ghosh

Blood (2024) 144 (5): 552–564.

https://doi.org/10.1182/blood.2023023528

Published: 2024

Includes: Supplemental data

Journal Articles

An international learning collaborative phase 2 trial for haploidentical bone marrow transplant in sickle cell disease

Blood (2024) 143 (25): 2654–2665.

https://doi.org/10.1182/blood.2023023301

Published: 2024

Includes: Supplemental data

Journal Articles

An oral carbon monoxide–releasing molecule protects against acute hyperhemolysis in sickle cell disease

Kim Anh Nguyen, Alessandro Matte, Roberta Foresti, Enrica Federti, Laurent Kiger, Cécile Lefebvre, Hakim Hocini, Yanis Pelinski, Hiroaki Kitagishi, Laura Bencheikh, France Pirenne, Lucia de Franceschi, Roberto Motterlini, Pablo Bartolucci

Blood (2024) 143 (24): 2544–2558.

https://doi.org/10.1182/blood.2023023165

Published: 2024

Includes: Supplemental data

Journal Articles

The influence of voxelotor on cerebral blood flow and oxygen extraction in pediatric sickle cell disease

Rowan O. Brothers, Katherine B. Turrentine, Mariam Akbar, Sydney Triplett, Hongting Zhao, Tara M. Urner, Adam Goldman-Yassen, Richard A. Jones, Jack Knight-Scott, Sarah S. Milla, Shasha Bai, Amy Tang, R. Clark Brown, Erin M. Buckley

Blood (2024) 143 (21): 2145–2151.

https://doi.org/10.1182/blood.2023022011

Published: 2024

Includes: Supplemental data

Journal Articles

Sickle cell disease iPSC-derived sensory neurons exhibit increased excitability and sensitization to patient plasma

Reilly L. Allison, Emily Welby, Vanessa Ehlers, Anthony Burand, Olena Isaeva, Damaris Nieves Torres, Janelle Highland, Amanda M. Brandow, Cheryl L. Stucky, Allison D. Ebert

Blood (2024) 143 (20): 2037–2052.

https://doi.org/10.1182/blood.2023022591

Published: 2024

Includes: Supplemental data

Journal Articles

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Ruth Namazzi, Caitlin Bond, Andrea L. Conroy, Dibyadyuti Datta, Abner Tagoola, Michael J. Goings, Jeong Hoon Jang, Russell E. Ware, Robert Opoka, Chandy C. John

Blood (2024) 143 (14): 1425–1428.

https://doi.org/10.1182/blood.2023021575

Published: 2024

Includes: Supplemental data

Journal Articles

Clearance of VWF by hepatic macrophages is critical for the protective effect of ADAMTS13 in sickle cell anemia mice

Huiping Shi, Liang Gao, Nicole Kirby, Bojing Shao, Xindi Shan, Mariko Kudo, Robert Silasi, John Michael McDaniel, Meixiang Zhou, Samuel McGee, Wei Jing, Florea Lupu, Audrey Cleuren, James N. George, Lijun Xia

Blood (2024) 143 (13): 1293–1309.

https://doi.org/10.1182/blood.2023021583

Published: 2024

Includes: Supplemental data

Journal Articles

Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease

Yongshuai Han, Chengjie Gao, Yunfeng Liu, Huan Zhang, Shihui Wang, Huizhi Zhao, Weili Bao, Xinhua Guo, Francesca Vinchi, Cheryl Lobo, Patricia Shi, Avital Mendelson, Larry Luchsinger, Hui Zhong, Karina Yazdanbakhsh, Xiuli An

Blood (2024) 143 (11): 1018–1031.

https://doi.org/10.1182/blood.2023021658

Published: 2024

Includes: Supplemental data

Journal Articles

Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease

Dina S. Parekh, William A. Eaton, Swee Lay Thein

Blood (2024) 143 (10): 866–871.

https://doi.org/10.1182/blood.2023021167

Published: 2024

Journal Articles

How I treat sickle cell disease in pregnancy

Andra H. James, John Joseph Strouse

Blood (2024) 143 (9): 769–776.

https://doi.org/10.1182/blood.2023020728

Published: 2024

Journal Articles

The challenge of clinical end points in sickle cell disease

Kenneth I. Ataga

Blood (2023) 142 (24): 2047–2054.

https://doi.org/10.1182/blood.2023021220

Published: 2023

Journal Articles

Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation

Zalaya K. Ivy, John D. Belcher, Iryna A. Khasabova, Chunsheng Chen, Joseph P. Juliette, Fuad Abdulla, Conglin Ruan, Kaje Allen, Julia Nguyen, Victoria M. Rogness, Joan D. Beckman, Sergey G. Khasabov, Kalpna Gupta, Ronald P. Taylor, Donald A. Simone, Gregory M. Vercellotti

Blood (2023) 142 (22): 1918–1927.

https://doi.org/10.1182/blood.2022019282

Published: 2023

Includes: Supplemental data

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17( R )-Resolvin D1 protects against sickle cell–related inflammatory cardiomyopathy in humanized mice

Sickle cell trait does not cause “sickle cell crisis” leading to exertion-related death: a systematic review

How I treat sickle cell disease with gene therapy

TR4 and BCL11A repress γ-globin transcription via independent mechanisms

Genotyped RhD + red cells for D-positive patients with sickle cell disease with conventional RHD and unexpected anti-D

Less-deformable erythrocyte subpopulations biomechanically induce endothelial inflammation in sickle cell disease

Significant pituitary siderosis is common in transfusion-dependent sickle cell disease

Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease

Heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice

An international learning collaborative phase 2 trial for haploidentical bone marrow transplant in sickle cell disease

An oral carbon monoxide–releasing molecule protects against acute hyperhemolysis in sickle cell disease

The influence of voxelotor on cerebral blood flow and oxygen extraction in pediatric sickle cell disease

Sickle cell disease iPSC-derived sensory neurons exhibit increased excitability and sensitization to patient plasma

Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

Clearance of VWF by hepatic macrophages is critical for the protective effect of ADAMTS13 in sickle cell anemia mice

Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease

Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease

How I treat sickle cell disease in pregnancy

The challenge of clinical end points in sickle cell disease

Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation

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