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Journal Articles

MLL1 Modulates IgM and Inflammatory Cytokines in Waldenstrom's Macroglobulinemia

Mona Karbalivand, MSc, BSc, Weiguo Han, PhD, Luciana L Almada, PhD, Stephen M Ansell, MD PhD, Martin Fernandez-Zapico, MD, Sherine F Elsawa, PhD

Blood (2019) 134 (Supplement_1): 3966.

https://doi.org/10.1182/blood-2019-125833

Published: 2019

Journal Articles

The Contribution of Proteasome Subunits to Myeloma Cell Viability and Proteasome Inhibitor Sensitivity

Chang-Xin Shi, PhD, Yuan Xiao Zhu, PhD, Laura Ann Bruins, BS, Cecilia Bonolo De Campos, PhD, William Stewart, Esteban Braggio, PhD, A Keith Stewart, M.B. Ch.B.

Blood (2019) 134 (Supplement_1): 4337.

https://doi.org/10.1182/blood-2019-127149

Published: 2019

Journal Articles

Effective Targeting of PRAME-Positive Tumors with Bispecific T Cell-Engaging Receptor (TCER ® ) Molecules

Sebastian Bunk, PhD, Martin Hofmann, PhD, Felix Unverdorben, PhD, Meike Hutt, PhD, Gabriele Pszolla, PhD, Frank Schwöbel, PhD, Claudia Wagner, PhD, Sara Yousef, PhD, Heiko Schuster, PhD, Sarah Missel, PhD, Oliver Schoor, PhD, Toni Weinschenk, PhD, Harpreet Singh-Jasuja, PhD, Dominik Maurer, PhD, Carsten Reinhardt, MD

Blood (2019) 134 (Supplement_1): 3368.

https://doi.org/10.1182/blood-2019-129958

Published: 2019

Journal Articles

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Catherine Rondelli, Aiden Danoff, Hector Bergonia, Samantha Gillis, Julia Free, John D. Phillips, PhD, Yvette Y Yien, PhD

Blood (2019) 134 (Supplement_1): 427.

https://doi.org/10.1182/blood-2019-132039

Published: 2019

Journal Articles

A Novel Approach to Assess Capacities of Red Cells in Dissolving Oxygen and Carrying Oxygen Based on a Portable Near-Infrared Spectroscopy Device

Ting Li, PhD, Yue Zhao, Master, Yunlong Sun, Master, Kai Li, Master, Wenjie Li, Meixue Duan, PhD, Chenyang Gao, PhD

Blood (2019) 134 (Supplement_1): 4792.

https://doi.org/10.1182/blood-2019-124003

Published: 2019

Journal Articles

Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia

Julia T Warren, MD PhD, Peeradol Wattanasirakul, David H Spencer, MD, Adam Locke, PhD, Vahagn Makaryan, MD, Audrey Anna Bolyard, RN, BS, Karl Welte, Julia Skokowa, MD PhD, David C. Dale, MD, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 433.

https://doi.org/10.1182/blood-2019-129635

Published: 2019

Journal Articles

In Vitro -Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies

Matthew Nix, PhD, Yu-Hsiu T. Lin, BA, Huimin Geng, PhD, Makeba Marcoulis, BA, Paul Phojanakong, BA, Donghui Wang, BA, Veronica Steri, PhD, Jeffrey Whitman, MD, Sagar Bapat, MD PhD, Elliot Stieglitz, MD, Anne Deucher, MD PhD, Kristie L White, MD MD, Byron C Hann, MD PhD, Arun P. Wiita, MD PhD

Blood (2019) 134 (Supplement_1): 1337.

https://doi.org/10.1182/blood-2019-130938

Published: 2019

Journal Articles

A Novel Cycs Missense Mutation in the α-Helix of the Cycs C-Terminal Domain Causes Non-Syndromic Thrombocytopenia

Yuri Uchiyama, MD PhD, Kunio Yanagisawa, MD PhD, Shinji Kunishima, PhD, Masaaki Shiina, MD PhD, Yoshiyuki Ogawa, MD PhD, Mitsuko Nakashima, MD PhD, Satoko Miyatake, MD PhD, Satomi Mitsuhashi, MD PhD, Atsushi Takata, MD PhD, Noriko Miyake, MD PhD, Kazuhiro Ogata, MD PhD, Hiroshi Handa, MD PhD, Naomichi Matsumoto, MD PhD, Takeshi Mizuguchi, MD PhD

Blood (2018) 132 (Supplement 1): 3758.

https://doi.org/10.1182/blood-2018-99-114729

Published: 2018

Journal Articles

"Switch" Transmembrane Immunomodulatory Proteins (TIPs) Consisting of High-Affinity PD-1 Extracellular Domains (PD-1 vIgDs) and Costimulatory Intracellular Domains Potently Enhance the Activity of TCR-Engineered T Cells

Steven D Levin, PhD, Hieu Nguyen, B.S., Joseph Kuijper, Rebecca P Wu, Ryan Swanson, B.S., Stanford L. Peng, MD, PhD

Blood (2018) 132 (Supplement 1): 2052.

https://doi.org/10.1182/blood-2018-99-117454

Published: 2018

Journal Articles

LUC7L2 Is a Novel RNA-Splicing Regulatory Factor Mutated in Myelodysplastic Syndromes

Courtney Hershberger, BS, James Hiznay, Rosemary Dietrich, Xiaorong Gu, PhD, Cassandra M. Hirsch, Amy Graham, BS, MS, Bartlomiej P. Przychodzen, Valeria Visconte, PhD, Vera Adema, PhD, Yvonne Parker, Hetty E. Carraway, MD MBA, Tomas Radivoyevitch, PhD, Mikkael A. Sekeres, MD MS, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, Richard A Padgett

Blood (2018) 132 (Supplement 1): 3073.

https://doi.org/10.1182/blood-2018-99-112838

Published: 2018

Journal Articles

Complications and Toxicities Associated with Autologous Stem Cell Transplantation for Severe Autoimmune Diseases: Single Center Experience

Shona Philip, BSc, MSc, MD, Christopher Bredeson, MD FRCPC, MSc, David S. Allan, MD FRCPC, MSc, Sultan Altouri, MD FRCPC, Lothar B. Huebsch, MD, Harold Atkins, MD, Natasha Kekre, MD FRCPC

Blood (2018) 132 (Supplement 1): 4624.

https://doi.org/10.1182/blood-2018-99-119797

Published: 2018

Journal Articles

Differential Effects of Pathogenic and Non-Pathogenic Early-Life Exposures on Acute Lymphoblastic Leukemia Progression in Eμ-RET Mice

Matthew Gynn, Mario Fidanza, Sumin Jo, Soren Gantt, Tobias R. Kollmann, Gregor S. D. Reid, PhD

Blood (2018) 132 (Supplement 1): 1422.

https://doi.org/10.1182/blood-2018-99-119718

Published: 2018

Journal Articles

Computational Identification of Tractable Drug-like Inhibitors of eIF4A1

Derek Essegian, BS, MS, Tyler A. Cunningham, BS, Jonathan H. Schatz, MD, Stephan Schurer, PhD

Blood (2018) 132 (Supplement 1): 5802.

https://doi.org/10.1182/blood-2018-99-116829

Published: 2018

Journal Articles

Deptor As a Target with Chemical Inhibitors; Alternative Therapy in Multiple Myeloma

Mario Vega, PhD, Patrick Frost, PhD, Carolyne Bardeleben, PhD, Yijiang Shi, MD PhD, Sara Huerta-Yepez, PhD, Alan Lichtenstein, MD

Blood (2017) 130 (Supplement 1): 3833.

https://doi.org/10.1182/blood.V130.Suppl_1.3833.3833

Published: 2017

Journal Articles

Inhibiting the Mitochondrial Sulfhydryl Oxidase Alr Reduces Cox17 and Alters Mitochondrial Cristae Structure Leading to the Differentiation of AML and Stem Cells

Danny V. Jeyaraju, PhD, Veronique Voisin, Changjiang Xu, Samir H. Barghout, BSPharm, MSc, Dilshad H. Khan, Rose Hurren, BSc, Marcela Gronda, MSc, Xiaoming Wang, Yulia Jitkova, PhD, David Sharon, PhD, Sanduni U. Liyanage, Hon. B. Sc, PhD, Joelle Soriano, Eric R. Lechman, PhD, Neil MacLean, Mark D. Minden, MD PhD, Steven M. Chan, MDPhD, John E. Dick, PhD, Gary D Bader, Aaron D. Schimmer, MDPhD

Blood (2017) 130 (Supplement 1): 881.

https://doi.org/10.1182/blood.V130.Suppl_1.881.881

Published: 2017

Journal Articles

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Rami Khoriaty, MD, Angela Weyand, MD, Geoffrey Hesketh, PhD, Amélie Bernard, PhD, Lesley Everett, MD PhD, Guojing Zhu, MD, Beth McGee, Bin Zhang, PhD, Daniel Klionsky, PhD, Anne-Claude Gingras, Jordan A. Shavit, MD PhD, David Ginsburg, MD

Blood (2017) 130 (Supplement 1): 80.

https://doi.org/10.1182/blood.V130.Suppl_1.80.80

Published: 2017

Journal Articles

Development of Novel Proteasome-HDAC6 Hybrid Inhibitors for Resistant ALL Phenotype

Sanil Bhatia, PhD, Nina Ressing, Alexandra Herrlich, Arndt Borkhardt, Prof MD, Finn Hansen, JProf. Dr., Julia Hauer, Prof. Dr.

Blood (2017) 130 (Supplement 1): 2070.

https://doi.org/10.1182/blood.V130.Suppl_1.2070.2070

Published: 2017

Journal Articles

Splitting the Functions of a Mitochondrial Iron/Pyrimidine Carrier

Simon A.B. Knight, PhD, Heeyong Yoon, PhD, Emmanuel Lesuisse, PhD, Debkumar Pain, PhD, Andrew Dancis, MD

Blood (2017) 130 (Supplement 1): 2213.

https://doi.org/10.1182/blood.V130.Suppl_1.2213.2213

Published: 2017

Journal Articles

Mitochondria-Targeted Effects of Water-Soluble Polyol-Methanofullerenes on Human Whole Blood Platelets, Lymphocytes and Granulocytes Ex Vivo

Gulzada Tarasova, PhDstudent, Natalia Kalacheva, PhD, Guzel Fazleeva, PhD, Valentina Gubskaya, PhD, Albert Rizvanov, DSc, PhD, Georgi Cherepnev, MD PhD

Blood (2017) 130 (Supplement 1): 4836.

https://doi.org/10.1182/blood.V130.Suppl_1.4836.4836

Published: 2017

Journal Articles

TAK-243 Is a Selective UBA1 Inhibitor That Displays Preclinical Activity in Acute Myeloid Leukemia (AML)

Samir H. Barghout, BSPharm, MSc, Parasvi Patel, BSc (Hons), Xiaoming Wang, G. Wei Xu, Simon Kavanagh, Marcela Gronda, MSc, Rose Hurren, BSc, Danny V. Jeyaraju, PhD, Neil MacLean, Marc Hyer, PhD, Allison Berger, PhD, Tary Traore, Michael Sintchak, Michael Milhollen, Mark D. Minden, MD PhD, Razq Hakem, PhD, Aaron D. Schimmer, MDPhD

Blood (2017) 130 (Supplement 1): 814.

https://doi.org/10.1182/blood.V130.Suppl_1.814.814

Published: 2017

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MLL1 Modulates IgM and Inflammatory Cytokines in Waldenstrom's Macroglobulinemia

The Contribution of Proteasome Subunits to Myeloma Cell Viability and Proteasome Inhibitor Sensitivity

Effective Targeting of PRAME-Positive Tumors with Bispecific T Cell-Engaging Receptor (TCER ® ) Molecules

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

A Novel Approach to Assess Capacities of Red Cells in Dissolving Oxygen and Carrying Oxygen Based on a Portable Near-Infrared Spectroscopy Device

Heterozygous Mutations of Clpb As a Newly Identified and Frequent Cause of Severe Congenital Neutropenia

In Vitro -Selected Nanobody-Based Cellular Therapy Targeting CD72 for Treatment of Refractory B-Cell Malignancies

A Novel Cycs Missense Mutation in the α-Helix of the Cycs C-Terminal Domain Causes Non-Syndromic Thrombocytopenia

"Switch" Transmembrane Immunomodulatory Proteins (TIPs) Consisting of High-Affinity PD-1 Extracellular Domains (PD-1 vIgDs) and Costimulatory Intracellular Domains Potently Enhance the Activity of TCR-Engineered T Cells

LUC7L2 Is a Novel RNA-Splicing Regulatory Factor Mutated in Myelodysplastic Syndromes

Complications and Toxicities Associated with Autologous Stem Cell Transplantation for Severe Autoimmune Diseases: Single Center Experience

Differential Effects of Pathogenic and Non-Pathogenic Early-Life Exposures on Acute Lymphoblastic Leukemia Progression in Eμ-RET Mice

Computational Identification of Tractable Drug-like Inhibitors of eIF4A1

Deptor As a Target with Chemical Inhibitors; Alternative Therapy in Multiple Myeloma

Inhibiting the Mitochondrial Sulfhydryl Oxidase Alr Reduces Cox17 and Alters Mitochondrial Cristae Structure Leading to the Differentiation of AML and Stem Cells

Overlap of SEC23A and SEC23B Function Suggests a Novel Therapeutic Approach for Congenital Dyserythropoietic Anemia Type II

Development of Novel Proteasome-HDAC6 Hybrid Inhibitors for Resistant ALL Phenotype

Splitting the Functions of a Mitochondrial Iron/Pyrimidine Carrier

Mitochondria-Targeted Effects of Water-Soluble Polyol-Methanofullerenes on Human Whole Blood Platelets, Lymphocytes and Granulocytes Ex Vivo

TAK-243 Is a Selective UBA1 Inhibitor That Displays Preclinical Activity in Acute Myeloid Leukemia (AML)

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