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Journal Articles

VEXAS syndrome

Peter C. Grayson, Bhavisha A. Patel, Neal S. Young
Journal: Blood
Blood (2021) 137 (26): 3591–3594.
https://doi.org/10.1182/blood.2021011455
Published: 2021
Journal Articles

Plasmablasts derive from CD23 – activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction

Amandine Pignarre, Fabrice Chatonnet, Gersende Caron, Marion Haas, Fabienne Desmots, Thierry Fest
Journal: Blood
Blood (2021) 137 (9): 1166–1180.
https://doi.org/10.1182/blood.2020005083
Published: 2021
Includes: Supplemental data
Journal Articles

LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells

Tomoyasu Jo, Momoko Nishikori, Yasunori Kogure, Hiroshi Arima, Katsuhiro Sasaki, Yoshiteru Sasaki, Tomoko Nakagawa, Fumie Iwai, Shuji Momose, Aki Shiraishi, Hiroshi Kiyonari, Noritaka Kagaya, Tetsuo Onuki, Kazuo Shin-ya, Minoru Yoshida, Keisuke Kataoka, Seishi Ogawa, Kazuhiro Iwai, Akifumi Takaori-Kondo
Journal: Blood
Blood (2020) 136 (6): 684–697.
https://doi.org/10.1182/blood.2019002654
Published: 2020
Includes: Supplemental data
Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker
Journal: Blood
Blood (2020) 135 (25): 2209–2210.
https://doi.org/10.1182/blood.2020005882
Published: 2020
Journal Articles

Wdr26 regulates nuclear condensation in developing erythroblasts

Ru Zhen, Chingyee Moo, Zhenzhen Zhao, Mengying Chen, He Feng, Xiaojun Zheng, Liang Zhang, Jiahai Shi, Caiyong Chen
Journal: Blood
Blood (2020) 135 (3): 208–219.
https://doi.org/10.1182/blood.2019002165
Published: 2020
Includes: Supplemental data
Journal Articles

Direct Phosphorylation and Stabilization of MYC By Aurora B Kinase Promotes T Cell Leukemogenesis

Hudan Liu, PhD, Jue Jiang, PhD, Jingchao Wang, PhD, Ming Yue, PhD, Hui Feng, MD PhD, Guoliang Qing, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 732.
https://doi.org/10.1182/blood-2019-130112
Published: 2019
Journal Articles

TRIP13 Modulates Protein Deubiquitination to Promote Myeloma Progression

Can Li, MD, Reinaldo Franqui-Machin, Jiliang Xia, PhD, Gregory S. Thomas, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Fangping Chen, MD PhD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 854.
https://doi.org/10.1182/blood-2019-123818
Published: 2019
Journal Articles

Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors

Max Jan, MD PhD, Ana Castano, MD, Amanda Walker, BA, Andrew A Guirguis, MD PhD, Jessica A Gasser, PhD, Amanda A Bouffard, Mikolaj Slabicki, PhD, Alexander Tepper, Daniel E Grinshpun, Taeyoon Kyung, PhD, Quinlan Sievers, MD PhD, Michael E Birnbaum, PhD, Marcela V Maus, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 866.
https://doi.org/10.1182/blood-2019-124210
Published: 2019
Journal Articles

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Tomoya Muto, MD PhD, Maria Guillamot, PhD, Jing Fang, MD PhD, Luna Zea Redondo, MS, Kwangmin Choi, PhD, Yixiao Gong, MSc, Callum S Walker, MSc, Kathleen Hueneman, Lyndsey C Bolanos, BSc, Laura Barreyro, PhD, Lynn Lee, MD, Kenneth D Greis, PhD, Alireza Khodadadi-Jamayran, M.Sc., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Iannis Aifantis, PhD, Daniel T. Starczynowski, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 727.
https://doi.org/10.1182/blood-2019-121423
Published: 2019
Journal Articles

A Phase 1b/2 Study of TAK-981, a First-in-Class Sumoylation Inhibitor, in Combination with Rituximab in Patients with Relapsed/Refractory (r/r) CD20-Positive Non-Hodgkin Lymphoma (NHL)

Sarit Assouline, MD, Amitkumar Mehta, MD, Paolo F Caimi, MD, Bingxia Wang, PhD, Chirag Patel, Mi-Sook Kim, Dennis Huszar, Allison J Berger, PhD, Sharon Friedlander, Alejandro Gomez-Pinillos, Igor Proscurshim
Journal: Blood
Blood (2019) 134 (Supplement_1): 1593.
https://doi.org/10.1182/blood-2019-128773
Published: 2019
Journal Articles

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

Taishi Yonezawa, MSc, Hirotaka Takahasi, PhD, Tatsuya Sawasaki, PhD, Toshio Kitamura, MD PhD, Susumu Goyama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1252.
https://doi.org/10.1182/blood-2019-126264
Published: 2019
Journal Articles

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Jibran Durrani, Hassan Awada, MD, Stephan Hutter, PhD, Kevin Fung, Francesca Gould, Christina A. Snider, BA, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Yogenthiran Saunthararajah, MD, Jennifer S. Carew, PhD, Manja Meggendorfer, PhD, James G Phillips, PhD, Mikkael A. Sekeres, MD MS, Michael R. Savona, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1281.
https://doi.org/10.1182/blood-2019-129196
Published: 2019
Journal Articles

PP2A Activators Enhance Efficacy of FLT3 Inhibitors in FLT3-ITD Acute Myeloid Leukemia Cells through AKT Inactivation-Dependent Pim-1 and c-Myc Proteasomal Degradation

Mario Scarpa, PhD, Prerna Singh, MS, Shivani Kapoor, MS, Jonelle K. Lee, MS, Sandrine Niyongere, MD, Goutham Narla, MD PhD, Danilo Perrotti, MD PhD, Maria R. Baer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1276.
https://doi.org/10.1182/blood-2019-129011
Published: 2019
Journal Articles

Single-Cell RNA-Seq to Assess Differential Responses to Tnfα in Human Hematopoietic Stem and Progenitor Cells in Myeloproliferative Neoplasm

Brianna Craver, MS, Quy Nguyen, Gajalakshmi Ramanathan, PhD, Angela G. Fleischman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2518.
https://doi.org/10.1182/blood-2019-123480
Published: 2019
Journal Articles

Role of Ubiquitin E3 Ligase UBR5 in B-Cell Development and Lymphoma

Tyler Gilbreath, B.S., Samantha Swenson, PhD, Shannon M. Buckley, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2794.
https://doi.org/10.1182/blood-2019-128747
Published: 2019
Journal Articles

FLT3 Is Sumoylated and Localizes to the Nucleus in Acute Myeloid Leukemia

Marisse Asong, MD MSc, Julhash Uddin Kazi, PhD, Lars Ronnstrand, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2733.
https://doi.org/10.1182/blood-2019-127914
Published: 2019
Journal Articles

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Ting Du, PhD, Yan Song, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3074.
https://doi.org/10.1182/blood-2019-130236
Published: 2019
Journal Articles

Identification of Deubiquitinase OTUD1 As a Novel Player in Resistance of Multiple Myeloma to Bortezomib

Alexander Vdovin, Tomas Jelinek, MD, Matous Hrdinka, PhD, Juli R. Bago, PhD, Tereza Sevcikova, Roman Hajek, Prof, MD PhD, Michal Simicek, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5526.
https://doi.org/10.1182/blood-2019-127930
Published: 2019
Journal Articles

FBXO11 Is a Candidate Tumor Suppressor in the Transformation of MDS to Secondary AML

Michael Schieber, MD, John D. Crispino, PhD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 4217.
https://doi.org/10.1182/blood-2019-124007
Published: 2019
Journal Articles

Pharmacologic Inhibition of SUMO-Activating Enzyme (SAE) with TAK-981 Augments Interferon Signaling and Regulates T Cell Differentiation in Ex Vivo studies of Chronic Lymphocytic Leukemia (CLL)

Vi Lam, Scott R Best, BS, Nur Bruss, BS, Tingting Liu, Taylor Hashiguchi Rowland, BS, Dennis Huszar, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1760.
https://doi.org/10.1182/blood-2019-127539
Published: 2019