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Journal Articles

Elotuzumab Enhances the Th2-Mediated Immune Response of Dendritic Cell Induced By Immunomodulatory Drugs (IMiDs)

Yoshiko Azuma, MD, Tomoki Ito, MD PhD, Muneo Inaba, PhD, Kai Imai, MD, Masaaki Hotta, MD, Atsushi Satake, MD PhD, Shosaku Nomura, MD PhD

Blood (2019) 134 (Supplement_1): 4342.

https://doi.org/10.1182/blood-2019-129680

Published: 2019

Journal Articles

Clinical Utility of Multiple-Gene Mutation Testing By Next-Generation Sequencing in Acute Myeloid Leukemia in Community Hospital Setting

Jingxin Sun, MD PhD, Luwei Tao, MD PhD, Rushang D. Patel, MD PhD, Shahram Mori, MD PhD, Jeff Chang, MD PhD

Blood (2018) 132 (Supplement 1): 4004.

https://doi.org/10.1182/blood-2018-99-119427

Published: 2018

Journal Articles

High-Dose TSLP Induces Co-Receptor Internalization and Signal Shutdown in Ph-like B-ALL with Overexpression of CRLF2

WayAnne B. Watson, Hossam Alkashgari, MD, Cornelia Stoian, PhD, Jacqueline S. Coats, Ineavely Baez, Hannah Choi, Benjamin Becerra, DrPH, Rishikesh Chavan, MD, Muhammad Omair Kamal, MD, Shadi Farzin Gohar, MD, Xianmei Meng, PhD, Sinisa Dovat, MD PhD, Kimberly J. Payne, PhD, Hoda Erjaee, DVM, PhD

Blood (2018) 132 (Supplement 1): 4024.

https://doi.org/10.1182/blood-2018-99-114336

Published: 2018

Journal Articles

Myeloma Cells Have the Ability to Suppress Th1-Inducing Capacity but Enhance Th2-Mediated Response of Dendritic Cells By Producing Factors Other Than Soluble SLAMF7

Yoshiko Azuma, MD, Tomoki Ito, MD PhD, Muneo Inaba, PhD, Kai Imai, MD, Hideaki Yoshimura, MD, Masaaki Hotta, MD, Takahisa Nakanishi, MD PhD, Shinya Fujita, MD PhD, Aya Nakaya, MD PhD, Atsushi Satake, MD PhD, Kazuyoshi Ishii, MDMPH,PhD, Shosaku Nomura, MD PhD

Blood (2018) 132 (Supplement 1): 1938.

https://doi.org/10.1182/blood-2018-99-113282

Published: 2018

Journal Articles

Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background

Mianmian Yin, PhD, Yang Jo Chung, PhD, R. Coleman Lindsley, MD, PhD, Yeulin Zhu, PhD, Robert L. Walker, PhD, Benjamin L. Ebert, MDPhD, Paul S. Meltzer, MD PhD, Peter D. Aplan, MD

Blood (2018) 132 (Supplement 1): 1331.

https://doi.org/10.1182/blood-2018-99-115388

Published: 2018

Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD

Blood (2018) 132 (Supplement 1): 566.

https://doi.org/10.1182/blood-2018-99-115913

Published: 2018

Journal Articles

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

Yan Xing, MDPhD, Heather Stefanski, MD PhD, Danny W. Bruce, PhD, Keli Lee Hippen, PhD, James M. Coghill, Jr., MD, Karen McKinnon, PhD, Shannon Reisdorf, BS, Bruce Blazar, MD, Jonathan S Serody, MD

Blood (2017) 130 (Supplement 1): 4432.

https://doi.org/10.1182/blood.V130.Suppl_1.4432.4432

Published: 2017

Journal Articles

Characterization of Causal Variants at the GATA3 Loci Associated with Susceptibility to Ph-like Acute Lymphoblastic Leukemia

Hui Zhang, PhD MD, Hongbo Yang, PhD, Tingting Liu, PhD, Maoxiang Qian, PhD, Wenjian Yang, PhD, Kathryn G. Roberts, PhD, Virginia Perez-Andreu, MD PhD, Heng Xu, PhD, Julie M. Gastier-Foster, PhD, Colton Smith, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MD, Mignon L. Loh, MD, Feng Yue, PhD, Jun J. Yang, PhD

Blood (2017) 130 (Supplement 1): 475.

https://doi.org/10.1182/blood.V130.Suppl_1.475.475

Published: 2017

Journal Articles

Biologic for the Treatment of Ph-like B-Cell Acute Lymphoblastic Leukemia with Overexpression of CRLF2

Cornelia Stoian, Jacqueline S. Coats, Veriah Vidales, Ineavely Baez, Juliette Personius, Hannah Choi, Lawrence Liu, Evgeny Chirshev, Hossam Alkashgari, Brandon Ng, Garcia Esmeralda, Benjamin Becerra, Rishikesh Chavan, Muhammad Omair Kamal, Shadi Farzin Gohar, Sinisa Dovat, Kimberly Payne

Blood (2017) 130 (Supplement 1): 2600.

https://doi.org/10.1182/blood.V130.Suppl_1.2600.2600

Published: 2017

Journal Articles

Finding active LCH cells in the blood

Oussama Abla

Blood (2017) 130 (17): 1874–1875.

https://doi.org/10.1182/blood-2017-09-805424

Published: 2017

Journal Articles

CD207 + CD1a + cells circulate in pediatric patients with active Langerhans cell histiocytosis

Eugenio Antonio Carrera Silva, Wanda Nowak, Licina Tessone, Cinthia Mariel Olexen, Juan Manuel Ortiz Wilczyñski, Ivana Gisele Estecho, Graciela Elena, Andrea Emilse Errasti, Diego Alfredo Rosso

Blood (2017) 130 (17): 1898–1902.

https://doi.org/10.1182/blood-2017-05-782730

Published: 2017

Includes: Supplemental data

Journal Articles

Immunomodulatory Drugs (IMiDs), Lenalidomide and Pomalidomide, Suppress Th1-Inducing Capacity of Dendritic Cells but Enhance Th2-Mediated Allergic Response

Tomoki Ito, M. D. and Ph. D., Phan Thi Xuan Vien, Muneo Inaba, Ph. D, Hideaki Yoshimura, MD, Masaaki Hotta, MD, Takahisa Nakanishi, MD PhD, Shinya Fujita, MD PhD, Aya Nakaya, MD PhD, Atsushi Satake, MD PhD, Kazuyoshi Ishii, MD MPH, PhD, Shosaku Nomura, MD PhD

Blood (2016) 128 (22): 2520.

https://doi.org/10.1182/blood.V128.22.2520.2520

Published: 2016

Journal Articles

CRLF2 Rearrangement Status in Ph-like ALL Predicts Intrinsic Glucocorticoid Resistance In Vitro that is Reversible with Targeted MAPK and PI3K Pathway Inhibition

Lauren K Meyer, Cristina Delgado-Martin, PhD, Shannon L Maude, MD PhD, David T Teachey, MD, Michelle L. Hermiston, MD PhD

Blood (2016) 128 (22): 910.

https://doi.org/10.1182/blood.V128.22.910.910

Published: 2016

Journal Articles

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Elisabeth M.P. Steeghs, MSc, Isabel S. Jerchel, MSc, Willemieke de Goffau-Nobel, MSc, Alex Q. Hoogkamer, BSc, Judith M. Boer, PhD, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Marco J. Koudijs, PhD, Nicolle J.M. Besselink, BSc, Hester A. de Groot-Kruseman, PhD, C. Michel Zwaan, MD PhD, Martin A. Horstmann, MD, Rob Pieters, MD PhD, Monique L. Den Boer, PhD

Blood (2016) 128 (22): 583.

https://doi.org/10.1182/blood.V128.22.583.583

Published: 2016

Journal Articles

A Patient-Derived Xenograft Model for Identifying Therapies and Defining Mechanisms of TSLP-Induced CRLF2 Signals in Ph-like B-ALL

Olivia L Francis, BS,PhD, Terry-Ann MIlford, BS, Ineavely Baez, BS, Jacqueline Coats, BS, Christopher L. Morris, MD PhD, Ross Fisher, MD, Benjamin Joseph Van Handel, BS, PhD, Ruijun Su, MD PhD, Batul T. Suterwala, MD, Shadi Farzingohar, MD, Sinisa Dovat, MD,PhD, Kimberly Payne, PhD

Blood (2015) 126 (23): 2633.

https://doi.org/10.1182/blood.V126.23.2633.2633

Published: 2015

Journal Articles

Three Steps to the Diagnosis of Adult Ph-like ALL

Annette Fasan, PhD, Wolfgang Kern, MD, Niroshan Nadarajah, M.Sc., Simone Weber, Sonja Schindela, Nicole Schlenther, Susanne Schnittger, PhD, Torsten Haferlach, Claudia Haferlach, MD

Blood (2015) 126 (23): 2610.

https://doi.org/10.1182/blood.V126.23.2610.2610

Published: 2015

Journal Articles

Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia

Blood (2015) 126 (23): 2529.

https://doi.org/10.1182/blood.V126.23.2529.2529

Published: 2015

Journal Articles

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Angela Maria Savino, Jolanda Sarno, Luca Trentin, Margherita Vieri, Grazia Fazio, PhD, Michela Bardini, Cristina Bugarin, Gianluca Fossati, Kara L. Davis, DO, Giuseppe Gaipa, PhD, Lueder Hinrich Meyer, MD, Garry P. Nolan, Prof, PhD, Andrea Biondi, Prof, MD, Geertruy Te Kronnie, PhD, Chiara Palmi, PhD, Giovanni Cazzaniga

Blood (2015) 126 (23): 2534.

https://doi.org/10.1182/blood.V126.23.2534.2534

Published: 2015

Journal Articles

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Roland P. Kuiper, PhD, Simon V. van Reijmersdal, Marieke Simonis, PhD, Jiangyan Yu, MSc, Edwin Sonneveld, PhD, Blanca Scheijen, PhD, Judith M. Boer, PhD, Aurélie Boeree, BSc, Petra Klous, MSc, Peter M Hoogerbrugge, MD PhD, Mehmet Yilmaz, MSc, Frank N. van Leeuwen, PhD, Monique L. Den Boer, PhD, Erik Splinter, PhD

Blood (2015) 126 (23): 696.

https://doi.org/10.1182/blood.V126.23.696.696

Published: 2015

Journal Articles

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Jolanda Sarno, Kara L. Davis, DO, Angela Maria Savino, PhD, Cristina Bugarin, Stefania Pinto, Chiara Buracchi, PhD, Astraea Jager, BS, Chiara Palmi, PhD, Ruth C Barber, PhD, Daniela Silvestri, Gianni Cazzaniga, PhD, Martin J.S. Dyer, Prof., Andrea Biondi, Prof, MD, Garry P. Nolan, Prof, PhD, Giuseppe Gaipa, PhD

Blood (2015) 126 (23): 906.

https://doi.org/10.1182/blood.V126.23.906.906

Published: 2015

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Elotuzumab Enhances the Th2-Mediated Immune Response of Dendritic Cell Induced By Immunomodulatory Drugs (IMiDs)

Clinical Utility of Multiple-Gene Mutation Testing By Next-Generation Sequencing in Acute Myeloid Leukemia in Community Hospital Setting

High-Dose TSLP Induces Co-Receptor Internalization and Signal Shutdown in Ph-like B-ALL with Overexpression of CRLF2

Myeloma Cells Have the Ability to Suppress Th1-Inducing Capacity but Enhance Th2-Mediated Response of Dendritic Cells By Producing Factors Other Than Soluble SLAMF7

Engineered Bcor Mutations Lead to Acute Lymphoblastic Leukemia of Progenitor B-1 Lymphocyte Origin in a Sensitized Background

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

Characterization of Causal Variants at the GATA3 Loci Associated with Susceptibility to Ph-like Acute Lymphoblastic Leukemia

Biologic for the Treatment of Ph-like B-Cell Acute Lymphoblastic Leukemia with Overexpression of CRLF2

Finding active LCH cells in the blood

CD207 + CD1a + cells circulate in pediatric patients with active Langerhans cell histiocytosis

Immunomodulatory Drugs (IMiDs), Lenalidomide and Pomalidomide, Suppress Th1-Inducing Capacity of Dendritic Cells but Enhance Th2-Mediated Allergic Response

CRLF2 Rearrangement Status in Ph-like ALL Predicts Intrinsic Glucocorticoid Resistance In Vitro that is Reversible with Targeted MAPK and PI3K Pathway Inhibition

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

A Patient-Derived Xenograft Model for Identifying Therapies and Defining Mechanisms of TSLP-Induced CRLF2 Signals in Ph-like B-ALL

Three Steps to the Diagnosis of Adult Ph-like ALL

Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

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