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Journal Articles

Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation

Ayako Nakamura-Ishizu, Desmond Wai Loon Chin, Takayoshi Matsumura, Darren Qiancheng Tan, Makiko Mochizuki-Kashio, Deng Jianwen, Toshio Suda
Journal: Blood
Blood (2021) 137 (19): 2609–2620.
https://doi.org/10.1182/blood.2020005517
Published: 2021
Includes: Supplemental data
Journal Articles

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Brief Report
Christian A. Di Buduo, Silvia Giannini, Vittorio Abbonante, Vittorio Rosti, Karin M. Hoffmeister, Alessandra Balduini
Journal: Blood
Blood (2021) 137 (15): 2085–2089.
https://doi.org/10.1182/blood.2020007265
Published: 2021
Includes: Supplemental data
Journal Articles

The role of AGK in thrombocytopoiesis and possible therapeutic strategies

Haojie Jiang, Zhuo Yu, Nan Ding, Mina Yang, Lin Zhang, Xuemei Fan, Yuan Zhou, Qiang Zou, Jian Hou, Junke Zheng, Lei Zhang, Yanyan Xu, Junling Liu
Journal: Blood
Blood (2020) 136 (1): 119–129.
https://doi.org/10.1182/blood.2019003851
Published: 2020
Includes: Supplemental data
Journal Articles

Mechanisms of anti-GPIbα antibody–induced thrombocytopenia in mice

Yosuke Morodomi, Sachiko Kanaji, Eric Won, Zaverio M. Ruggeri, Taisuke Kanaji
Journal: Blood
Blood (2020) 135 (25): 2292–2301.
https://doi.org/10.1182/blood.2019003770
Published: 2020
Includes: Supplemental data
Journal Articles

Romiplostim in patients undergoing hematopoietic stem cell transplantation: results of a phase 1/2 multicenter trial

Clinical Trials & Observations
Régis Peffault de Latour, Sylvie Chevret, Anna Lisa Ruggeri, Felipe Suarez, Laetitia Souchet, David Michonneau, Flore Sicre de Fontbrune, Tereza Coman, Nathalie Dhedin, Marie Thérèse Rubio, Stéphanie Nguyen, Mohamad Mohty, Gérard Socié
Journal: Blood
Blood (2020) 135 (3): 227–229.
https://doi.org/10.1182/blood.2019000358
Published: 2020
Includes: Supplemental data
Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 472.
https://doi.org/10.1182/blood-2019-131432
Published: 2019
Journal Articles

Enhanced Transduction Lentivector Gene Therapy for Treatment of Older Patients with X-Linked Severe Combined Immunodeficiency

Suk See De Ravin, MD, PhD, Sandra Anaya O'Brien, Nana Kwatemaa, RN, MSN, CCRP, Narda Theobald, BS, Siyuan Liu, Janet Lee, BS, Lela Kardava, Taylor Liu, Frederick Goldman, MDMS, Susan Moir, Jack Bleesing, MD PhD, Benedicte Neven, MD PhD, Jennifer Puck, MD, Morton J Cowan, MD, Ewelina Mamcarz, MD, Stephen Gottschalk, MD, Michael M Meagher, PhD, Luigi Notarangelo, MD, Elizabeth Kang, MD, Xiaolin Wu, PhD, Harry L. Malech, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 608.
https://doi.org/10.1182/blood-2019-127439
Published: 2019
Journal Articles

Megakaryocyte Reprogramming in Breast Cancer

Harvey G. Roweth, BSc, PhD, Michael Malloy, BS, Gregory Goreczny, BS, PhD, Kelly E. Johnson, BS, PhD, Sandra S. McAllister, PhD, Joseph E. Italiano, Jr., BS, PhD, Elisabeth Battinelli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 12.
https://doi.org/10.1182/blood-2019-124894
Published: 2019
Journal Articles

Development of CD38 CAR Engineered Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells (PNK-CAR38) As Allogeneic Cancer Immunotherapy

Srinivas Somanchi, PhD, Xuan Guo, PhD, Shuyang He, PhD, Rohit Mathur, PhD, Andrea Difiglia, BS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Gunnar F. Kaufmann, PhD, Jerome B. Zeldis, MD PhD, Henry Ji, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2070.
https://doi.org/10.1182/blood-2019-129539
Published: 2019
Journal Articles

A Meta-Analysis on the Efficacy of Thrombopoietin (TPO) Agonists in Reducing the Need of Platelet Transfusion before Procedures in Chronic Liver Disease Patients

Michael Jaglal, MD, Damian A. Laber, MD, Ankita K. Patel, MD, Mintallah Haider, MD, Jennifer Eatrides, MD, Nathan Visweshwar, MD, Hesham Abowali, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2108.
https://doi.org/10.1182/blood-2019-129521
Published: 2019
Journal Articles

Engineering High Affinity and Cleavage Resistant CD16 to Augment ADCC of Placental Hematopoietic Stem Cells-Derived Natural Killer Cells

Xuan Guo, PhD, Srinivas Somanchi, PhD, Rohit Mathur, PhD, Shuyang He, PhD, Qian Ye, PhD, Andrea Difiglia, BS, Salvatore Rotondo, MS, Hemlata Rana, MS, Weifang Ling, PhD, James Edinger, PhD, Robert Hariri, MD PhD, Xiaokui Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1576.
https://doi.org/10.1182/blood-2019-127009
Published: 2019
Journal Articles

Transcriptional Landscape of the Microenvironment in Bone Marrow Fibrosis at Single Cell Level

Nils B. Leimkühler, Ronghui Li, MSc, Helene Gleitz, PhD, Inge Snoeren, MSc, Stijn Fuchs, Martina Crysandt, MD, Steffen Koschmieder, Christoph Kuppe, MD, Guntram Buesche, MD, Hans H Kreipe, MD PhD, Ivan Costa, PhD, Rafael Kramann, MD PhD, Rebekka K. Schneider, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1675.
https://doi.org/10.1182/blood-2019-126897
Published: 2019
Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

Germline Mutations Predispose to Familial Myeloproliferative Neoplasms

Stephanie Berg, DO, Manuel O. Diaz, MD, Sucha Nand, MD, Jiwang Zhang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2969.
https://doi.org/10.1182/blood-2019-124805
Published: 2019
Journal Articles

Biomarkers of Response to Romiplostim in Patients with Lower-Risk Myelodysplastic Syndrome (MDS) and Thrombocytopenia - Results of the Europe Trial By the Emsco Network

Uwe Platzbecker, MD, Anne Sophie Kubasch, MD, Aristoteles Giagounidis, MD, Georgia Metzgeroth, Anna Jonasova, MD PhD, Regina Herbst, MD, Jose Miguel Torregrosa Diaz, Benoit De Renzis, MD, Katharina Götze, Marie-Luise Huetter-Kroenke, MD, Marie-Pierre Gourin, Borhane Slama, MD, Sophie Dimicoli-Salazar, MD, Pascale Cony-Makhoul, MD, Kamel Laribi, MD, Sophie Park, MD PhD, Katja Jersemann, Oliver Tiebel, MD, Katja Sockel, MD, Silke Gloaguen, MSc, Anna Mies, Fatiha Chermat, Christian Thiede, MD, Rosa Sapena, Richard F. Schlenk, MD, Pierre Fenaux, MD PhD, Lionel Ades, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2998.
https://doi.org/10.1182/blood-2019-129047
Published: 2019
Journal Articles

Understanding the Mechanisms Underlying Thrombocytopenia in Visceral Leishmaniasis

Gulab Fatima Rani, MBBS, Olivier Preham, PhD, Ian Hitchcock, PhD, Paul Kaye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2378.
https://doi.org/10.1182/blood-2019-128133
Published: 2019
Journal Articles

CD244 Marks Non-Functional Hematopoietic Stem Cells with a Mast Cell Signature after Induction of Endoplasmic Reticulum Stress

Valgardur Sigurdsson, PhD, Shuhei Koide, PhD, Visnja Radulovic, PhD, Els Mansell, PhD, Mark Van Der Garde, MSc, PhD, Tiit Örd, PhD, Tonis Örd, PhD, Kenichi Miharada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2474.
https://doi.org/10.1182/blood-2019-128239
Published: 2019
Journal Articles

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

Zhi-Jian Liu, PhD, Emoke Deschmann, MD, Haley E. Ramsey, PhDMSc, Henry Feldman, Bethan Psaila, MD PhD, Nichola Cooper, MD MRCP, Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, John B. Porter, MA MDFRCP FRCPath, James B. Bussel, MD, Michael Georgieff, MD, Martha Sola-Visner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2475.
https://doi.org/10.1182/blood-2019-131895
Published: 2019
Journal Articles

Endocytosis of the Thrombopoietin Receptor Mpl Regulates Both Megakaryocyte and Erythroid Maturation in Mice

Nathan Eaton, BS, Melissa M. Lee-Sundlov, PhD, Theresa A. Dlugi, PhD, Jon Wieser, BS, Haley E. Ramsey, PhDMSc, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD, Hervé Falet, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2477.
https://doi.org/10.1182/blood-2019-126820
Published: 2019
Journal Articles

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Amandeep Kaur, PhD, Katherine M Hannan, PhD, Samina Nazir, MSc, Kylee H Maclachlan, FRACP,FRCPA, Gretchen Poortinga, PhD, Si Ming Man, PhD, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Ross D Hannan, PhD, Elizabeth E. Gardiner, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2360.
https://doi.org/10.1182/blood-2019-121713
Published: 2019