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Journal Articles

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

Blood (2021) 138 (14): 1258–1268.

https://doi.org/10.1182/blood.2020010331

Published: 2021

Includes: Supplemental data

Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood (2021) 138 (3): 259–272.

https://doi.org/10.1182/blood.2020006198

Published: 2021

Includes: Supplemental data

Journal Articles

Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

Kaushik Das, Shiva Keshava, Shabbir A. Ansari, Vijay Kondreddy, Charles T. Esmon, John H. Griffin, Usha R. Pendurthi, L. Vijaya Mohan Rao

Blood (2021) 137 (24): 3428–3442.

https://doi.org/10.1182/blood.2020008417

Published: 2021

Includes: Supplemental data

Journal Articles

FV/FVa revealed

Josefin Ahnström

Blood (2021) 137 (22): 3011–3013.

https://doi.org/10.1182/blood.2021011573

Published: 2021

Journal Articles

Cryo-EM structures of human coagulation factors V and Va

Eliza A. Ruben, Michael J. Rau, James A. J. Fitzpatrick, Enrico Di Cera

Blood (2021) 137 (22): 3137–3144.

https://doi.org/10.1182/blood.2021010684

Published: 2021

Includes: Supplemental data

Journal Articles

Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy

James R. Fuller, Kevin E. Knockenhauer, Nina C. Leksa, Robert T. Peters, Joseph D. Batchelor

Blood (2021) 137 (21): 2970–2980.

https://doi.org/10.1182/blood.2020009197

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

Lauren G. Poole, Anna K. Kopec, Dafna J. Groeneveld, Asmita Pant, Kevin S. Baker, Holly M. Cline-Fedewa, Matthew J. Flick, James P. Luyendyk

Blood (2021) 137 (18): 2520–2531.

https://doi.org/10.1182/blood.2020007415

Published: 2021

Includes: Supplemental data

Journal Articles

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes

Fredy Delgado Lagos, Amro Elgheznawy, Anastasia Kyselova, Dagmar Meyer zu Heringdorf, Corina Ratiu, Voahanginirina Randriamboavonjy, Alexander W. Mann, Beate Fisslthaler, Mauro Siragusa, Ingrid Fleming

Blood (2021) 137 (12): 1641–1651.

https://doi.org/10.1182/blood.2020009405

Published: 2021

Includes: Supplemental data

Journal Articles

Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model

Manuel J. Feinauer, Stefan W. Schneider, Anna S. Berghoff, Jose Ramon Robador, Cedric Tehranian, Matthia A. Karreman, Varun Venkataramani, Gergely Solecki, Julia Katharina Grosch, Katharina Gunkel, Bogdana Kovalchuk, Frank Thomas Mayer, Manuel Fischer, Michael O. Breckwoldt, Maik Brune, Yannick Schwab, Wolfgang Wick, Alexander T. Bauer, Frank Winkler

Blood (2021) 137 (9): 1219–1232.

https://doi.org/10.1182/blood.2020005710

Published: 2021

Includes: Supplemental data

Journal Articles

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

Jing Wang, Yongxiang Gao, Lan Chen, Yugang Guo, Siyi Hu, Liansheng Cheng, Weihua Xiao, Jiyuan Ke, Zhongliang Zhu, Liwen Niu

Blood (2021) 137 (6): 844–847.

https://doi.org/10.1182/blood.2020008028

Published: 2021

Includes: Supplemental data

Journal Articles

Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus

Sara Calzavarini, Raja Prince-Eladnani, François Saller, Luca Bologna, Laurent Burnier, Anne C. Brisset, Claudia Quarroz, Maria Desiré Reina Caro, Vladimir Ermolayev, Yasuhiro Matsumura, José A. Fernández, Tilman M. Hackeng, John H. Griffin, Anne Angelillo-Scherrer

Blood (2020) 135 (22): 1969–1982.

https://doi.org/10.1182/blood.2019003630

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Erica M. Sparkenbaugh, Chunsheng Chen, Tomasz Brzoska, Julia Nguyen, Shaobin Wang, Gregory M. Vercellotti, Nigel S. Key, Prithu Sundd, John D. Belcher, Rafal Pawlinski

Blood (2020) 135 (20): 1783–1787.

https://doi.org/10.1182/blood.2019003543

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg

Blood (2020) 135 (19): 1704–1717.

https://doi.org/10.1182/blood.2019004267

Published: 2020

Includes: Supplemental data

Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Blood (2020) 135 (17): 1484–1496.

https://doi.org/10.1182/blood.2019001292

Published: 2020

Includes: Supplemental data

Journal Articles

Acetylsalicylic acid inhibits intravascular coagulation during Staphylococcus aureus –induced sepsis in mice

Agostina Carestia, Rachelle P. Davis, Heidi Grosjean, Matthew W. Lau, Craig N. Jenne

Blood (2020) 135 (15): 1281–1286.

https://doi.org/10.1182/blood.2019002783

Published: 2020

Includes: Supplemental data

Journal Articles

Thromboinflammatory effects of RBC microvesicles

Evi X. Stavrou

Blood (2020) 135 (10): 708–709.

https://doi.org/10.1182/blood.2020004985

Published: 2020

Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key

Blood (2020) 135 (10): 755–765.

https://doi.org/10.1182/blood.2019001643

Published: 2020

Includes: Supplemental data

Journal Articles

The protein C activator AB002 rapidly interrupts thrombus development in baboons

Erik I. Tucker, Norah G. Verbout, Brandon D. Markway, Michael Wallisch, Christina U. Lorentz, Monica T. Hinds, Joseph J. Shatzel, Leslie A. Pelc, David C. Wood, Owen J. T. McCarty, Enrico Di Cera, András Gruber

Blood (2020) 135 (9): 689–699.

https://doi.org/10.1182/blood.2019002771

Published: 2020

Includes: Supplemental data

Journal Articles

Inhibition of Complement C1s with Sutimlimab in Patients with Cold Agglutinin Disease (CAD): Results from the Phase 3 Cardinal Study

Alexander Röth, Wilma Barcellini, Shirley D'Sa, Yoshitaka Miyakawa, Catherine M Broome, Marc Michel, David J. Kuter, Bernd Jilma, Tor Henrik Anderson Tvedt, Stella Lin, Xiaoyu Jiang, Caroline Reuter, William Hobbs, Sigbjørn Berentsen

Blood (2019) 134 (Supplement_2): LBA-2.

https://doi.org/10.1182/blood-2019-132490

Published: 2019

Journal Articles

Low factor V level ameliorates bleeding diathesis in patients with combined deficiency of factor V and factor VIII

Yanyan Shao, Wenman Wu, Guanqun Xu, Xuefeng Wang, Qiulan Ding

Blood (2019) 134 (20): 1745–1754.

https://doi.org/10.1182/blood.2018886069

Published: 2019

Includes: Supplemental data

NARROW

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

FV/FVa revealed

Cryo-EM structures of human coagulation factors V and Va

Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy

Factor XIII cross-links fibrin(ogen) independent of fibrin polymerization in experimental acute liver injury

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes

Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model

Structure of the platelet glycoprotein Ib receptor in complex with a novel antithrombotic agent

Platelet protein S limits venous but not arterial thrombosis propensity by controlling coagulation in the thrombus

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Acetylsalicylic acid inhibits intravascular coagulation during Staphylococcus aureus –induced sepsis in mice

Thromboinflammatory effects of RBC microvesicles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

The protein C activator AB002 rapidly interrupts thrombus development in baboons

Inhibition of Complement C1s with Sutimlimab in Patients with Cold Agglutinin Disease (CAD): Results from the Phase 3 Cardinal Study

Low factor V level ameliorates bleeding diathesis in patients with combined deficiency of factor V and factor VIII

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American Society of Hematology

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American Society of Hematology

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