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Journal Articles

CLL-IPI: valid in the era of oral inhibitors?

Nadine Kutsch
Journal: Blood
Blood (2021) 138 (2): 106–107.
https://doi.org/10.1182/blood.2021011937
Published: 2021
Journal Articles

Acalabrutinib in treatment-naive chronic lymphocytic leukemia

Clinical Trials & Observations
John C. Byrd, Jennifer A. Woyach, Richard R. Furman, Peter Martin, Susan O’Brien, Jennifer R. Brown, Deborah M. Stephens, Jacqueline C. Barrientos, Stephen Devereux, Peter Hillmen, John M. Pagel, Ahmed Hamdy, Raquel Izumi, Priti Patel, Min Hui Wang, Nitin Jain, William G. Wierda
Journal: Blood
Blood (2021) 137 (24): 3327–3338.
https://doi.org/10.1182/blood.2020009617
Published: 2021
Includes: Supplemental data
Journal Articles

Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia

CME Clinical Trials & Observations
Yair Herishanu, Irit Avivi, Anat Aharon, Gabi Shefer, Shai Levi, Yotam Bronstein, Miguel Morales, Tomer Ziv, Yamit Shorer Arbel, Lydia Scarfò, Erel Joffe, Chava Perry, Paolo Ghia
Journal: Blood
Blood (2021) 137 (23): 3165–3173.
https://doi.org/10.1182/blood.2021011568
Published: 2021
Includes: Supplemental data
Journal Articles

The miR-185/PAK6 axis predicts therapy response and regulates survival of drug-resistant leukemic stem cells in CML

Hanyang Lin, Katharina Rothe, Min Chen, Andrew Wu, Artem Babaian, Ryan Yen, Jonathan Zeng, Jens Ruschmann, Oleh I. Petriv, Kieran O'Neill, Tobias Maetzig, David J. H. F. Knapp, Naoto Nakamichi, Ryan Brinkman, Inanc Birol, Donna L. Forrest, Carl Hansen, R. Keith Humphries, Connie J. Eaves, Xiaoyan Jiang
Journal: Blood
Blood (2020) 136 (5): 596–609.
https://doi.org/10.1182/blood.2019003636
Published: 2020
Includes: Supplemental data
Journal Articles

Occupy BTK: the key to controlling CLL

Philip A. Thompson
Journal: Blood
Blood (2020) 136 (1): 4–6.
https://doi.org/10.1182/blood.2020005877
Published: 2020
Journal Articles

A complementary new drug for PNH

Clinical Trials & Observations
Robert A. Brodsky
Journal: Blood
Blood (2020) 135 (12): 884–885.
https://doi.org/10.1182/blood.2020004959
Published: 2020
Journal Articles

The complement C5 inhibitor crovalimab in paroxysmal nocturnal hemoglobinuria

Clinical Trials & Observations
Alexander Röth, Jun-ichi Nishimura, Zsolt Nagy, Julia Gaàl-Weisinger, Jens Panse, Sung-Soo Yoon, Miklos Egyed, Satoshi Ichikawa, Yoshikazu Ito, Jin Seok Kim, Haruhiko Ninomiya, Hubert Schrezenmeier, Simona Sica, Kensuke Usuki, Flore Sicre de Fontbrune, Juliette Soret, Alexandre Sostelly, James Higginson, Andreas Dieckmann, Brittany Gentile, Judith Anzures-Cabrera, Kenji Shinomiya, Gregor Jordan, Marta Biedzka-Sarek, Barbara Klughammer, Angelika Jahreis, Christoph Bucher, Régis Peffault de Latour
Journal: Blood
Blood (2020) 135 (12): 912–920.
https://doi.org/10.1182/blood.2019003399
Published: 2020
Includes: Supplemental data
Journal Articles

Treatment-naive CLL: lessons from phase 2 and phase 3 clinical trials

Clinical Trials & Observations
Jennifer A. Woyach
Journal: Blood
Blood (2019) 134 (21): 1796–1801.
https://doi.org/10.1182/blood.2019001321
Published: 2019
Journal Articles

Integrative Immunogenomic Characterization of Diffuse Large B-Cell Lymphoma (DLBCL) Identifies Four Molecular Subtypes with Distinct Immune Landscapes

Michael Leukam, MDMS, James Godfrey, MD, Sravya Tumuluru, Girish Venkataraman, MD MBBS, Sonali M. Smith, MD, Riyue Bao, PhD, Justin Kline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 924.
https://doi.org/10.1182/blood-2019-131562
Published: 2019
Journal Articles

High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade during Ibrutinib Therapy in CLL Patients

Giorgia Chiodin, David Dutton, MD, Enrica Antonia Martino, MD, Samantha Drennan, PhD, Ian Tracy, PhD, Laura Ondrisova, Isla Henderson, Annalisa D'Avola, PhD, Christina Pitsillidou, Marek Mraz, MD, Peter Johnson, MDFRCP, Andrew Duncombe, MD, Graham Packham, PhD, Andrew J Steele, PhD, Helen Parker, PhD, Silvia Bonfiglio, Lydia Scarfo, MD, Lesley-Ann Sutton, Paolo Ghia, MD PhD, Matthew John Jerome Rose-Zerilli, PhD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 1752.
https://doi.org/10.1182/blood-2019-128899
Published: 2019
Journal Articles

A Phase 1 First-in-Human Study of the Anti-CD38 Dimeric Fusion Protein TAK-169 for the Treatment of Patients (pts) with Relapsed or Refractory Multiple Myeloma (RRMM) Who Are Proteasome Inhibitor (PI)- and Immunomodulatory Drug (IMiD)-Refractory, Including Pts Relapsed/Refractory (R/R) or Naïve to Daratumumab (dara)

Shaji K. Kumar, MD, Robert F. Cornell, MD MS, Ola Landgren, MD PhD, Sikander Ailawadhi, MD, Jack P Higgins, PhD, Erin K Willert, Roger Waltzman, MD MBA, Jianchang Lin, PhD, Yuhong Zhang, Anya R Lublinsky, Ajeeta B Dash, PhD, Michael Hanley, Divya Manoharan, Morgan Leichter, Sean Ottinger, Richard J Labotka, John Newcomb, Alexander Vorog, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1867.
https://doi.org/10.1182/blood-2019-125629
Published: 2019
Journal Articles

Ibrutinib and Rituximab Provides Superior Clinical Outcome Compared to FCR in Younger Patients with Chronic Lymphocytic Leukemia (CLL): Extended Follow-up from the E1912 Trial

Tait D. Shanafelt, MD, Victoria Wang, Neil E. Kay, MD, Curtis A. Hanson, MD, Susan M. O'Brien, MD, Jacqueline C. Barrientos, MD MS, Diane F Jelinek, PhD, Esteban Braggio, PhD, Jose F. Leis, MD PhD, Cong Christina Zhang, Steven Coutre, MD, Paul M. Barr, MD, Amanda F Cashen, MD, Anthony R. Mato, MD MSCE, Avina Singh, MD, Michael P. Mullane, MD, Richard F. Little, MD MPH, Harry P. Erba, MD PhD, Richard M. Stone, MD, Mark Litzow, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 33.
https://doi.org/10.1182/blood-2019-126824
Published: 2019
Journal Articles

ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Jeff P. Sharman, MD, Versha Banerji, MD, Laura Maria Fogliatto, MD PhD, Yair Herishanu, MD, Talha Munir, MD, Renata Walewska, George Follows, Karin Karlsson, MD, Paolo Ghia, MD PhD, Gillian Corbett, Patricia Walker, MBBS, Miklos Egyed, Wojciech Jurczak, MD PhD, Gilles Salles, MD PhD, Ann Janssens, Florence Cymbalista, MD PhD, William G. Wierda, MD PhD, Steven Coutre, MD, John M. Pagel, MD PhD DSc, Alan Skarbnik, MD, Manali Kamdar, MD, Jennifer Woyach, MD, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Priti Patel, MD, Min Hui Wang, PhD, Sofia Wong, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 31.
https://doi.org/10.1182/blood-2019-128404
Published: 2019
Journal Articles

Health-Related Quality-of-Life Outcomes in Patients with Classical Hodgkin Lymphoma: A Prospective, Observational Study in US Oncology Practices

Jakub Svoboda, MD, Philippe Armand, MD PhD, Fiona Taylor, Xiaowu Sun, Alejandro Moreno-Koehler, Srikanth Gajavelli, MD, Derek Peterson, Clara Chen, PhD BS, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2192.
https://doi.org/10.1182/blood-2019-123980
Published: 2019
Journal Articles

Evolution in Practice Patterns and Differences Among Experts and Community Healthcare Providers in the Treatment of Patients with Chronic Lymphocytic Leukemia

Bing-E Xu, PhD, Kristen M Rosenthal, PhD, Krista Marcello, BA, Farrukh T. Awan, MD, Steven Coutre, MD, Nicole Lamanna, MD, Jeff P. Sharman, MD, Timothy A Quill, PhD, Kevin L Obholz, PhD, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4724.
https://doi.org/10.1182/blood-2019-129266
Published: 2019
Journal Articles

Response to the Shingrix Varicella Zoster Virus (VZV) Vaccine in Patients with Chronic Lymphocytic Leukemia (CLL) That Are Treatment Naive or Treated with a Bruton's Tyrosine Kinase Inhibitor (BTK-I)

Christopher Pleyer, MD, Jeffrey Cohen, MD, Susan Soto, Mir Ali, PhD, Inhye E Ahn, MD, Pia Nierman, BSN, MA, RN, Janet Valdez, Jennifer Lotter, PA-C, Jeanine Superata, RN, Xin Tian, Adrian Wiestner, MD PhD, Clare Sun, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3053.
https://doi.org/10.1182/blood-2019-121675
Published: 2019
Journal Articles

Brentuximab Vedotin in Front-Line Therapy of Hodgkin Lymphoma (HL) and CD30-Expressing Peripheral T-Cell Lymphoma (PTCL) in Adults Age 60 and Above

Christopher A. Yasenchak, MD, Rodolfo Bordoni, MD, Victor Yazbeck, MD, Dipti Patel-Donnelly, MD, Timothy Larson, MD, Trevor Newhook, MS, Linda Ho, Matthew Mei, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2852.
https://doi.org/10.1182/blood-2019-122968
Published: 2019
Journal Articles

Platelet Dysfunction Detected Using Rotational Thromboelastometry (ROTEM) in Severely Thrombocytopenic Patients with a Bleeding Phenotype

Philip Young-Ill Choi, BSc, MBBS, PhD, Sarah Hicks, Elizabeth E. Gardiner, PhD, Philip Crispin, MBBS, FRACP, FRCPA, James Slade, BN, GCCaN, MNNP, James D'Rozario, MBBS, FRACP, FRCPA, Christopher Parish, PhD, Lucy Coupland, PhDBSc,RN
Journal: Blood
Blood (2019) 134 (Supplement_1): 2357.
https://doi.org/10.1182/blood-2019-132232
Published: 2019
Journal Articles

High Surface Expression of CD49d (VLA-4) and CD79b Correlates with Acalabrutinib Resistance in Patients with Chronic Lymphocytic Leukemia (CLL)

Elena Bibikova, Brian Law, Tracy Clevenger, PhD, Jean Cheung, MS, Gary De Jesus, Michael Gulrajani, Kyoko Yamaguchi, Phuong Do, Kathleen Burke, PhD, Graham Brock, PhD, Veerendra Munugalavadla, PhD, Melanie M. Frigault, PhD, John C. Byrd, MD, Richard R. Furman, MD, Jennifer R. Brown, MD PhD, Todd Covey
Journal: Blood
Blood (2019) 134 (Supplement_1): 2571.
https://doi.org/10.1182/blood-2019-128872
Published: 2019
Journal Articles

Individualized Mitochondrial Functional Approach to Combination of BCL-2 and MCL-1 Antagonism in Acute Myeloid Leukemia

Shruti Bhatt, PhD, Marissa Pioso, Elyse Ann Olesinski, Binyam Yilma, Leutz Buon, Sophia Adamia, PhD, Holly Zhu, Jeremy Ryan, Youzhen Wang, Morris Erick, Ensar Halilovic, David M. Weinstock, MD, Jacqueline S Garcia, MD, Anthony Letai
Journal: Blood
Blood (2019) 134 (Supplement_1): 2551.
https://doi.org/10.1182/blood-2019-131101
Published: 2019