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Journal Articles

CLL cells are moved by the MARCKS brothers

Jan A. Burger

Blood (2021) 138 (7): 503–504.

DOI: https://doi.org/10.1182/blood.2021011650

Published: 2021

Journal Articles

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel K. Griffin, Pei-Hsuan Chen, Ana Lako, Robert A. Redd, Claire M. Cote, Matthew D. Ducar, Aaron R. Thorner, Scott J. Rodig, Gad Getz, Margaret A. Shipp

Blood (2019) 134 (26): 2369–2382.

DOI: https://doi.org/10.1182/blood.2019002067

Published: 2019

Includes: Supplemental data

Journal Articles

Integrated Single Cell Transcriptomics Defines an Engineered Niche Supporting Hematopoietic Stem Cell Development Ex Vivo

Brandon Hadland, MD PhD, Barbara Varnum-Finney, PhD, Stacey Dozono, Tessa Dignum, Cynthia Nourigat-Mckay, Dana Jackson, Shahin Rafii, MD, Cole Trapnell, PhD, Irwin D. Bernstein, MD

Blood (2019) 134 (Supplement_1): 3699.

DOI: https://doi.org/10.1182/blood-2019-126109

Published: 2019

Journal Articles

Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors

Ai-Ning Xu, Dan Liu, Yu-Ting Dai, Fan Zhang, Jian Shen, MSc, Cheng-Long Hu, Chun-Hui Xu, Yuan-Liang Zhang, Yin-Yin Xie, Qiu-Hua Huang, Peng-Fei Xu, Lan Wang, Lin Cheng, Jinyan Huang, PhD, Zhu Chen, PhD, Sai-Juan Chen, PhD, Xiao-Jian Sun, PhD

Blood (2019) 134 (Supplement_1): 3700.

DOI: https://doi.org/10.1182/blood-2019-130429

Published: 2019

Journal Articles

Anti-Tumor Effect of the EZH1/2 Dual Inhibitor Valemetostat Against Diffuse Large B-Cell Lymphoma Via Modulation of B-Cell Receptor Signaling and c-Myc Signaling Pathways

Yasuhiro Hama, PhD, Toshihiro Banjo, PhD, Daisuke Honma, PhD, Yoshimi Takata, Emi Nosaka, Machiko Shiroishi, Kenji Watanabe, Yuka Yamamoto, Tsuyoshi Hirata, Rika Nakano, Koichiro Inaki, PhD, Hiroki Goto, PhD, Yusuke Totoki, PhD, Miki Kataoka, Kyungtaek Lim, PhD, Chisa Wada, Eiji Kumazawa, PhD, Shinji Tsutsumi, PhD

Blood (2019) 134 (Supplement_1): 4642.

DOI: https://doi.org/10.1182/blood-2019-125436

Published: 2019

Journal Articles

Analysis of a New Haematopoietic Stem/Progenitor Cells with Megakaryocyte Differentiation Potential

Mo Yang, MD, Shichao Chen, Liang Li, PhD, Hongwu Xin, Beng H Chong, MBBS, PhD, Liuming Yang

Blood (2019) 134 (Supplement_1): 4891.

DOI: https://doi.org/10.1182/blood-2019-127851

Published: 2019

Journal Articles

ME-401-003 (TIDAL): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Phase 2 Study of ME-401 Investigating Continuous and Intermittent Dosing Schedules in Patients with Relapsed/Refractory Follicular Lymphoma

Andrew D. Zelenetz, MD PhD, Pier Luigi Luigi Zinzani, MD, Henry Chan, MBChB, Christian Buske, MD PhD, Vincent Ribrag, David Cunningham, MD FRCP, FMedSci, Wojciech Jurczak, Pau Abrisqueta, MD PhD, Joanne Li, Igor Gorbatchevsky, MD, Jennifer R. Brown, MD PhD

Blood (2019) 134 (Supplement_1): 5244.

DOI: https://doi.org/10.1182/blood-2019-124326

Published: 2019

Journal Articles

Oncogene-Independent Adaptation of Pre-B Cell Receptor Signaling Confers Drug Resistance and Signaling Plasticity in Ph-like ALL

Christian Hurtz, PhD, Gerald Wertheim, MD, PhD, Joseph Patrick Loftus, BS, Daniel Blumenthal, PhD, Anne Lehman, Yong Li, Bryan Manning, Katherine D Cummins, BMBS, Janis K Burkhardt, PhD, Alexander E. Perl, MD, Martin Carroll, MD, Sarah K. Tasian, MD

Blood (2019) 134 (Supplement_1): 747.

DOI: https://doi.org/10.1182/blood-2019-123514

Published: 2019

Journal Articles

GATA2 -Dependent Developmental and Regenerative Networks

Alexandra Soukup, PhD, Kirby D Johnson, PhD, Daniel J Conn, PhD, Evgenia Shishkova, PhD, Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Erik A. Ranheim, MD PhD, Katherine R. Calvo, MD PhD, Amy P. Hsu, Steven M. Holland, MD, Joshua J Coon, PhD, Sunduz Keles, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 1182.

DOI: https://doi.org/10.1182/blood-2019-126875

Published: 2019

Journal Articles

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Gregory Lazarian, PharmD, Shanye Yin, PhD, Elisa Ten Hacken, PhD, Tomasz Sewastianik, MSc,PhD, Alba Font-tello, PhD, Heather Joyal, Elizabeth Witten, Mei Zheng, Christopher J. Ott, PhD, Donna S Neuberg, ScD, Lili Wang, MD PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 848.

DOI: https://doi.org/10.1182/blood-2019-123963

Published: 2019

Journal Articles

Regulation of eIF4E Guides a Unique Translational Program to Steer Erythroid Maturation

Craig M Forester, MD PhD, Gun Woo-Byeon, Juan Oses-Prieto, PhD, Al Burlingame, PhD, Maria Barna, PhD, Davide M Ruggero, PhD

Blood (2019) 134 (Supplement_1): 156.

DOI: https://doi.org/10.1182/blood-2019-129608

Published: 2019

Journal Articles

BCR-ABL1 p190 in CML: A Minor Breakpoint with a Major Impact

Shady Adnan Awad, MD, Helena Hohtari, MD, Komal Kumar Javarappa, PhD, Tania Brandstoetter, Daehong Kim, Swapnil Potdar, MSc, Caroline A Heckman, PhD, Soili Kytölä, PhD, Kimmo Porkka, Eszter Doma, PhD, Veronika Sexl, MD PhD, Matti Kankainen, PhD, Satu Mustjoki, MD PhD

Blood (2019) 134 (Supplement_1): 190.

DOI: https://doi.org/10.1182/blood-2019-126584

Published: 2019

Journal Articles

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

Scott R Best, BS, Vi Lam, Nur Bruss, BS, Taylor Hashiguchi Rowland, BS, Adam S. Kittai, MD, Tingting Liu, Allison J Berger, PhD, Alexey Danilov, MD PhD

Blood (2019) 134 (Supplement_1): 4313.

DOI: https://doi.org/10.1182/blood-2019-123600

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

DOI: https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

Ingrid G Winkler, PhD, Valerie Barbier, Masters, Joshua Tay, PhD, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Corrine E Fiveash, BSc(Hons), Johanna D Erbani

Blood (2019) 134 (Supplement_1): 2657.

DOI: https://doi.org/10.1182/blood-2019-132212

Published: 2019

Journal Articles

Elevated ANXA1 Expression Causes Glucocorticoid Resistance in Acute Lymphoblastic Leukemia Via Activating the Wnt/β-Catenin Signaling Pathway

Ping Liu, Dan Ma, MD, Jishi Wang, PhD

Blood (2019) 134 (Supplement_1): 5198.

DOI: https://doi.org/10.1182/blood-2019-130322

Published: 2019

Journal Articles

Decitabine, Etoposide-Based Regimen Greatly Improved T53 Mutation Elderly AML/MDS Survival By Activating Notch1 Signaling Pathway

Jiexian Ma, MD, Xie Yanhui, Wu Min, Sun Shunrong

Blood (2019) 134 (Supplement_1): 5409.

DOI: https://doi.org/10.1182/blood-2019-125735

Published: 2019

Journal Articles

The Inspire Study in Higher-Risk Myelodysplastic Syndrome (HR-MDS): A Novel Phase 3 Study Adaptive Design for Hematological Malignancies in Adults

Anna Jonasova, MD PhD, Selina M. Luger, MD FRCPC, Aref Al-Kali, MD, David Valcarcel, Richard C. Woodman, MD, Afoluso Ronnee Adesanya, MD, Nozar Azarnia, PhD, Matthew Parris, Erica D. Warlick, MD, Wieslaw W. Jedrzejczak, MD PhD, María Díez-Campelo, MD PhD, Guillermo Garcia-Manero, MD

Blood (2019) 134 (Supplement_1): 4249.

DOI: https://doi.org/10.1182/blood-2019-132127

Published: 2019

Journal Articles

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Yan Xu, PhD, Xiang-ming Zha, PhD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 3719.

DOI: https://doi.org/10.1182/blood-2019-125168

Published: 2019

Journal Articles

PTPN11 Mutated Acute Myeloid Leukemia (AML) Features an Abundant Epichaperome Network and Is Sensitive to the Epichaperome Inhibitor PU-H71

Justin D. Kaner, MD, Montreh Tavakkoli, MA,MD, Lisa Toudic, Brett M. Stevens, PhD, Craig T Jordan, PhD, Tony Taldone, PhD, Gabriela Chiosis, PhD, Ellen K. Ritchie, MD, Pinkal Desai, MDMPH, Michael B. Samuel, MD, Sangmin Lee, MD, Gail J. Roboz, MD, Monica L. Guzman, PhD

Blood (2019) 134 (Supplement_1): 3935.

DOI: https://doi.org/10.1182/blood-2019-128276

Published: 2019

NARROW

CLL cells are moved by the MARCKS brothers

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Integrated Single Cell Transcriptomics Defines an Engineered Niche Supporting Hematopoietic Stem Cell Development Ex Vivo

Differential Expression of CD49f Discriminates the Independently Emerged Hematopoietic Stem Cells and Erythroid-Biased Progenitors

Anti-Tumor Effect of the EZH1/2 Dual Inhibitor Valemetostat Against Diffuse Large B-Cell Lymphoma Via Modulation of B-Cell Receptor Signaling and c-Myc Signaling Pathways

Analysis of a New Haematopoietic Stem/Progenitor Cells with Megakaryocyte Differentiation Potential

ME-401-003 (TIDAL): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Phase 2 Study of ME-401 Investigating Continuous and Intermittent Dosing Schedules in Patients with Relapsed/Refractory Follicular Lymphoma

Oncogene-Independent Adaptation of Pre-B Cell Receptor Signaling Confers Drug Resistance and Signaling Plasticity in Ph-like ALL

GATA2 -Dependent Developmental and Regenerative Networks

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Regulation of eIF4E Guides a Unique Translational Program to Steer Erythroid Maturation

BCR-ABL1 p190 in CML: A Minor Breakpoint with a Major Impact

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

Elevated ANXA1 Expression Causes Glucocorticoid Resistance in Acute Lymphoblastic Leukemia Via Activating the Wnt/β-Catenin Signaling Pathway

Decitabine, Etoposide-Based Regimen Greatly Improved T53 Mutation Elderly AML/MDS Survival By Activating Notch1 Signaling Pathway

The Inspire Study in Higher-Risk Myelodysplastic Syndrome (HR-MDS): A Novel Phase 3 Study Adaptive Design for Hematological Malignancies in Adults

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

PTPN11 Mutated Acute Myeloid Leukemia (AML) Features an Abundant Epichaperome Network and Is Sensitive to the Epichaperome Inhibitor PU-H71

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American Society of Hematology

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ASH Publications

American Society of Hematology

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