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Journal Articles

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate

Reiner K. Mailer, Mikel Allende, Marco Heestermans, Michaela Schweizer, Carsten Deppermann, Maike Frye, Giordano Pula, Jacob Odeberg, Mathias Gelderblom, Stefan Rose-John, Albert Sickmann, Stefan Blankenberg, Tobias B. Huber, Christian Kubisch, Coen Maas, Stepan Gambaryan, Dmitri Firsov, Evi X. Stavrou, Lynn M. Butler, Thomas Renné
Journal: Blood
Blood (2021) 137 (10): 1392–1405.
DOI: https://doi.org/10.1182/blood.2019004617
Published: 2021
Includes: Supplemental data
Journal Articles

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

Clinical Trials & Observations
Aileen G. Rowan, Richard Dillon, Aviva Witkover, Anat Melamed, Maria-Antonietta Demontis, Nicolas A. Gillet, Liew Jun Mun, Charles R. M. Bangham, Lucy B. Cook, Paul A. Fields, Graham P. Taylor
Journal: Blood
Blood (2020) 135 (23): 2023–2032.
DOI: https://doi.org/10.1182/blood.2019002665
Published: 2020
Includes: Supplemental data
Journal Articles

Improved Overall Survival Among Newly Diagnosed Aggressive Adult T-Cell Leukemia/Lymphoma Patients Treated with Mogamulizumab Plus EPOCH Compared to Mogamulizumab Plus Vcap-AMP-Vecp

Tatsuro Jo, MD PhD, Kaori Matsuzaka, Haruna Shioya, Hiroo Tominaga, Takahiro Sakai, Yohei Kaneko, Shizuka Hayashi, Masatoshi Matsuo, MD, PhD, Jun Taguchi, MD PhD, Kazuto Shigematsu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4048.
DOI: https://doi.org/10.1182/blood-2019-123984
Published: 2019
Journal Articles

F-Deletion Non-Integrating Measles Virus Vector: A Promising Tool for T-Cell Engineering and Naive iPSCs Generation

Jiyuan Liao, PhD, Yasushi Soda, MD PhD, Ai Sugawara, B.Sc., Yoshie Miura, PhD, Takafumi Hiramoto, PhD, Maino Tahara, PhD, Yuto Takishima, M.S., Shohei Miyamoto, PhD, Makoto Takeda, MD PhD, Kenzaburo Tani, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5750.
DOI: https://doi.org/10.1182/blood-2019-131593
Published: 2019
Journal Articles

Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage

Camélia Benlabiod, Maira da Costa Cacemiro, PhD, Thomas Balligand, MD, Barbara Panneau-Schmaltz, PhD, Delphine Muller, Laure Touchard, Patrick Gonin, DVM, Jean-Luc Villeval, PhD, Stefan N Constantinescu, MD PhD, Hana Raslova, PhD, William Vainchenker, MD PhD, Isabelle Plo, Caroline Marty, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 311.
DOI: https://doi.org/10.1182/blood-2019-127918
Published: 2019
Journal Articles

Evaluating Metabolic Regulation of Human Erythropoiesis By Profiling Nutrient Transporter Expression

David Justus, MD, Hongxia Yan, MS, John Hale, PhD, Lionel Blanc, PhD, Floriane Bitaudeau, MS, Vincent Petit, DVM, PhD, Sandrina Kinet, PhD, Marc Sitbon, PhD, Naomi Taylor, MD PhD, Mohandas Narla, DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 342.
DOI: https://doi.org/10.1182/blood-2019-124380
Published: 2019
Journal Articles

Inducible MyD88 Signaling Enhances the Anti-AML Activity of BiTE-Secreting ENG T-Cells

Abishek Vaidya, MS, Erin E Doherty, MD, Xiya Wu, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4441.
DOI: https://doi.org/10.1182/blood-2019-125395
Published: 2019
Journal Articles

Understanding the Mechanisms Driving Genomic Instability in Adult T-Cell Leukemia/Lymphoma

Advaitha Madireddy, PhD, Angelica Barreto-Galvez, B. Hilda Ye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5042.
DOI: https://doi.org/10.1182/blood-2019-121565
Published: 2019
Journal Articles

Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib

Azusa Mayumi, MD, Toshihiro Tomii, MD, Toshihiko Imamura, MD PhD, Machiko Kawamura, MD, Hajime Hosoi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5044.
DOI: https://doi.org/10.1182/blood-2019-126592
Published: 2019
Journal Articles

Development of a Genetically-Engineered Allogeneic Anti-CD38 T Cell Therapy Utilizing a Novel Antigen Receptor Structure

Bei Bei Ding, PhD, John Dixon Gray, PhD, Irina Krapf, MSc, Yanliang Zhang, PhD, Nan Zhang, Qingdong Mark Deng, Angel Wei, MD, Robert D. Knight, MD, Jerome B. Zeldis, MD PhD, Gunnar F. Kaufmann, PhD, Henry Ji, PhD, Wenzhong Guo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4444.
DOI: https://doi.org/10.1182/blood-2019-131586
Published: 2019
Journal Articles

Evolving Data on CAR T-Cell Therapy for Multiple Myeloma, Novel Targets, Conditioning Regimens and Novel Constructs: A Systematic Review

Yusra Shao, MD, Daniel S Carlson, DO, Faiz Anwer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5547.
DOI: https://doi.org/10.1182/blood-2019-122292
Published: 2019
Journal Articles

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

Catriona Jamieson, MD PhD, Qingfei Jiang, PhD, Frida Holm, PhD, Jane Isquith, MS, Adam Mark, Cayla Mason, BS, Wenxue Ma, MD PhD, Raymond H Diep, Jessica Pham, B.S., Eduardo Reynoso Moreno, PhD, Chanond A Nasamran, Xu Guorong, Amanda Birmingham, Leslie A Crews, PhD, Ludmil Alexandrov, Gabriel Pineda, PhD, Thomas Whisenant, Kathleen M Fisch
Journal: Blood
Blood (2019) 134 (Supplement_1): 3780.
DOI: https://doi.org/10.1182/blood-2019-131510
Published: 2019
Journal Articles

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Takashi Ishio, Joji Shimono, Sarvesh Kumar, Yuquan Lin, Emmanuel Bachy, Michael N. Petrus, Yandan Yang, Michiyuki Maeda, Hideki Goto, Satoshi Hashino, Takanori Teshima, MD, Thomas A. Waldmann, MD, Louis Staudt, MD, Masao Nakagawa
Journal: Blood
Blood (2019) 134 (Supplement_1): 3781.
DOI: https://doi.org/10.1182/blood-2019-124670
Published: 2019
Journal Articles

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Hiroo Katsuya, MD, Paola Miyazato, PhD, Saiful Islam, Benjy Jek Yang Tan, MD, Yuki Inada, Misaki Matsuo, Takaharu Ueno, Masahito Tokunaga, MD PhD, Hiroyuki Hata, MD PhD, Makoto Yamagishi, PhD, Jun-Ichi Fujisawa, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD, Atae Utsunomiya, MD, Shinya Kimura, MD PhD, Yorifumi Satou, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2779.
DOI: https://doi.org/10.1182/blood-2019-124361
Published: 2019
Journal Articles

The Role of the Lipid Raft-Associated Protein Flotillin-2 during Development and Progression of Myeloid Leukaemia

Rahul Kumar, PhD, Raquel Pereira, M.Sc, Julian Niemann, Costanza Zanetti, MSc, Alex Azimpour, Melanie Meister, PhD, Parimala Sonika Godavarthy, MSc, Daniela S. Krause, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2921.
DOI: https://doi.org/10.1182/blood-2019-122670
Published: 2019
Journal Articles

Potent Synergy between Combination of Chimeric Antigen Receptor (CAR) Therapy Targeting CD19 in Conjunction with Dendritic Cell (DC)/Tumor Fusion Vaccine in Hematological Malignancies

Marzia Capelletti, PhD MMSc, Jessica Liegel, MD, Maria Themeli, MD PhD, Tuna Mutis, Dina Stroopinsky, PhD, Shira Orr, PhD, Daniela Torres, Adam Morin, Gertrude Gunset, BA, Haider Ghiasuddin, Maryam Rahimian, MD, Myrna Nahas, MD, Lina Bisharat, Shufen Meng, MD, Nikhil C. Munshi, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, Michel Sadelain, MD PhD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3227.
DOI: https://doi.org/10.1182/blood-2019-124944
Published: 2019
Journal Articles

T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain Induce Remissions in Patients with Relapsed Multiple Myeloma

Lekha Mikkilineni, MD, Elisabet E. Manasanch, MD, Norris Lam, BS, Danielle Vanasse, BS, Jennifer N. Brudno, MD, Irina Maric, MD MSci, Jeremy J. Rose, MS, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, David F. Stroncek, MD, Jennifer Mann, CRNP, Micaela Ganadan, BSN, RN, Rashmika Patel, Nathan Trinklein, PhD, Ben Buelow, MD PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3230.
DOI: https://doi.org/10.1182/blood-2019-129088
Published: 2019
Journal Articles

FF-10101 Retains Potent Inhibitory Activities Against Resistant Mutations to FLT3 Inhibitors, Newly Identified in Random Mutagenesis Screens

Yuichi Ishikawa, MD PhD, Koichi Saito, PhD, Naomi Kawashima, MD PhD, Michie Morimoto, Hidetoshi Murao, PhD, Daisuke Terada, Takeshi Yamaura, Shinji Hagiwara, PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2672.
DOI: https://doi.org/10.1182/blood-2019-124632
Published: 2019
Journal Articles

Homeobox Transcription Factor Hhex Promotes Myeloid Leukemia in Cooperation with Mutant ASXL1

Reina Takeda, MD, Shuhei Asada, MD PhD, Sung-Joon Park, PhD, Akihiko Yokoyama, PhD, Akinori Kanai, PhD, Valeria Visconte, PhD, Courtney Hershberger, BS, Yasutaka Hayashi, MD PhD, Taishi Yonezawa, MSc, Moe Tamura, Tomofusa Fukuyama, MD PhD, Akiko Matsumoto, Satoshi Yamasaki, PhD, Kenta Nakai, PhD, Toshiya Inaba, MD PhD, Tatsuhiro Shibata, MD PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Susumu Goyama, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Toshio Kitamura, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2525.
DOI: https://doi.org/10.1182/blood-2019-126663
Published: 2019
Journal Articles

Overexpression or Deficiency of RUNX3 Results in Defective Normal Human Hematopoietic Development Similar to RUNX1-ETO Expression in AML

Ana Catarina Menezes, MSc, BSc, Steven Knapper, DM, Richard L Darley, PhD, Alex Tonks, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2527.
DOI: https://doi.org/10.1182/blood-2019-130798
Published: 2019