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Journal Articles

Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Srinivas Aluri, Kimo Bachiashvili, MD, Anjali Budhathoki, MD, Tushar D Bhagat, PhD, Gaurav S Choudhary, PhD, Shanisha Gordon, Nandini Ramachandra, Kith Pradhan, PhD, Shahina Maqbool, Aditi Shastri, MD, Jung Im Huh, Sunjin Hwang, Kim Seong-Jin, PhD, Hui Zhang, Britta Will, PhD, Amittha Wickrema, PhD, Ulrich G. Steidl, MD PhD, Amit Verma, MBBS

Blood (2019) 134 (Supplement_1): 2990.

https://doi.org/10.1182/blood-2019-127561

Published: 2019

Journal Articles

Regulatory Reprogramming of Erythropoiesis By DNMT3A Mutation

Janghee Woo, MDPhD, Sandra Stehling-Sun, PhD, H. Joachim Deeg, MD, Thalia Papayannopoulou, MD DrSci, Fyodor D Urnov, PhD, John A Stamatoyannopoulos, MD

Blood (2018) 132 (Supplement 1): 4343.

https://doi.org/10.1182/blood-2018-99-120110

Published: 2018

Journal Articles

Identification of a Novel CEBPE Enhancer Essential for Granulocytic Differentiation

Pavithra Shyamsunder, PhD, Mahalakshmi Shanmugasundaram, Anand Mayakonda, Weoi Woon Teoh, Lin Han, MSc, Mei Chee Lim, Melissa Fullwood, Omer An, Henry Yang, PhD, Shi Jizhong, Md.Zakhir Hossain, Vikas Madan, PhD, H. Phillip Koeffler, MD

Blood (2018) 132 (Supplement 1): 3834.

https://doi.org/10.1182/blood-2018-99-116091

Published: 2018

Journal Articles

The Role of Notch in Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

Quy Le, PhD, Brandon Hadland, MD PhD, Soheil Meshinchi, MD PhD, Irwin D. Bernstein, MD

Blood (2018) 132 (Supplement 1): 3947.

https://doi.org/10.1182/blood-2018-99-119735

Published: 2018

Journal Articles

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Alberto Bueno-Costa, David Piñeyro, Marta Soler, Biola Maria Javierre, José Angel Martínez-Climent, Manel Esteller, MD PhD

Blood (2018) 132 (Supplement 1): 5115.

https://doi.org/10.1182/blood-2018-99-111580

Published: 2018

Journal Articles

Expression of the Human Alpha-Globin Cluster in the Absence of the Major Regulatory Element Mcs-R2

Mohsin Badat, MBBChir, James O.J. Davies, PhD, Eduard J. van Beers, MD PhD, Cornelis Harteveld, PhD, Damien Downes, PhD, Douglas R. Higgs, FRS

Blood (2018) 132 (Supplement 1): 3632.

https://doi.org/10.1182/blood-2018-99-116209

Published: 2018

Journal Articles

Potent and Timed Epigenetic Repression of PD-1 in Human T Cells

Jocelynn Pearl, PhD, Fyodor D Urnov, PhD, John A Stamatoyannopoulos, MD

Blood (2018) 132 (Supplement 1): 3493.

https://doi.org/10.1182/blood-2018-99-119011

Published: 2018

Journal Articles

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

Nicole Stokes, BA, David Dominguez-Sola, MD PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 1323.

https://doi.org/10.1182/blood-2018-99-110829

Published: 2018

Journal Articles

DNA Methylation Identifies Genetically and Prognostically Distinct Subtypes of MDS

Brian M Reilly, BS, Tiffany N Tanaka, MD, Dinh Diep, PhD, Huwate Yeerna, BS, Pablo Tamayo, PhD, Kun Zhang, PhD, Rafael Bejar, MD PhD

Blood (2018) 132 (Supplement 1): 106.

https://doi.org/10.1182/blood-2018-99-111535

Published: 2018

Journal Articles

NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling

Pablo R. Freire, Orla M. Conneely

Blood (2018) 131 (10): 1081–1093.

https://doi.org/10.1182/blood-2017-07-795757

Published: 2018

Includes: Supplemental data

Journal Articles

Epigenetic Control of Foxp3, CAMTA1 and FUT7 Genes in Human Regulatory T Cells

Ekaterina Minskaia, PhD, Barbara C Saraiva, Maria Soares, PhD, Ana I.S. Vieira, MSc, Joao F Lacerda, MD PhD

Blood (2017) 130 (Supplement 1): 1004.

https://doi.org/10.1182/blood.V130.Suppl_1.1004.1004

Published: 2017

Journal Articles

Genome-Wide Analysis of the Regulatory Landscape in Different Pre-B-ALL Subtypes

Mari Lahnalampi, MSc, Juha Mehtonen, MSc, Susanna Teppo, MSc, Saara Laukkanen, MSc, Laura Oksa, MSc, Markus Muschen, MD, Olli Lohi, MD PhD, Merja Heinäniemi, PhD

Blood (2017) 130 (Supplement 1): 3807.

https://doi.org/10.1182/blood.V130.Suppl_1.3807.3807

Published: 2017

Journal Articles

Comparison of Fetal and Adult Erythroid Chromosomal Architectures Identifies a Novel Fetal Hemoglobin Regulatory Region

Peng Huang, PhD, Cheryl A. Keller, PhD, Belinda Giardine, James O.J. Davies, Jim R. Hughes, Ross C Hardison, PhD, Gerd Blobel, MD PhD

Blood (2017) 130 (Supplement 1): 774.

https://doi.org/10.1182/blood.V130.Suppl_1.774.774

Published: 2017

Journal Articles

GWAS of Complete Blood Count (CBC) Measures in 13,403 Blood Donors in the Multi-Racial RBC-Omics Study Reveal Novel Genetic Loci in Minority Populations Which Provide Insights into the Pathways That May Connect Them to Disease

Yuelong Guo, PhD, Grier Page, PhD BS, MS, Alan E. Mast, MDPhD, Richard G. Cable, MD, Bryan R Spencer, MPH, Joseph Kiss, MD, Stacey Endres, MPH, Steven Kleinman, MD, Michael Paul Busch, MD PhD

Blood (2017) 130 (Supplement 1): 921.

https://doi.org/10.1182/blood.V130.Suppl_1.921.921

Published: 2017

Journal Articles

Systematic Assessment of GATA2 Genetic Variation Reveals the Presence of Novel Disease-Causing Synonymous Exonic Mutations

Blood (2017) 130 (Supplement 1): 2449.

https://doi.org/10.1182/blood.V130.Suppl_1.2449.2449

Published: 2017

Journal Articles

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Andrew Volk, PhD, Kaiwei Liang, PhD, Jianyun Zhao, Xinyu Li, Marinka Bulic, Stacy Marshall, Jeffrey W. Taub, MD, Yubin Ge, PhD, Sebastien Malinge, PhD, Elizabeth Bartom, PhD, Ali Shilatifard, PhD, John D. Crispino, PhD

Blood (2017) 130 (Supplement 1): 245.

https://doi.org/10.1182/blood.V130.Suppl_1.245.245

Published: 2017

Journal Articles

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Elena Masselli, MD, Cecilia Carubbi, PhD, Benedetta Cambò, MD, Giulia Pozzi, MS, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Elena Follini, MD, Luca Pagliaro, MD, Francesco Bonatti, PhD, Antonio Percesepe, MD PhD, Franco Aversa, MD, Marco Vitale, MD

Blood (2017) 130 (Supplement 1): 5286.

https://doi.org/10.1182/blood.V130.Suppl_1.5286.5286

Published: 2017

Journal Articles

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

Mira Jeong, PhD, Yong Lei, PhD, Ivan Bochkov, Muhammad S Shamim, B.S., Anna G Guzman, Su-Chen Huang, M.S., Olga Dudchenko, PhD, Ido Machol, Michael C Gundry, BS, Huthayfa Mujahed, MS.c, Soren Lehmann, Erez S Lieberman, PhD, Margaret A Goodell, PhD

Blood (2016) 128 (22): 1466.

https://doi.org/10.1182/blood.V128.22.1466.1466

Published: 2016

Journal Articles

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 708.

https://doi.org/10.1182/blood.V128.22.708.708

Published: 2016

Journal Articles

A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function

Vikram R Paralkar, MD, Cristian Taborda, Yu Yao, MD, Rishi Prasad, Jing Luan, Ross C. Hardison, PhD, Gerd A. Blobel, MD PhD, Mitchell J Weiss, MD PhD

Blood (2015) 126 (23): 1175.

https://doi.org/10.1182/blood.V126.23.1175.1175

Published: 2015

NARROW

Clinical ALK5 Inhibitor, Vactosertib, Reverses TGFβ-1 Stimulated Smad-2 Driven Ineffective Hematopoiesis in MDS

Regulatory Reprogramming of Erythropoiesis By DNMT3A Mutation

Identification of a Novel CEBPE Enhancer Essential for Granulocytic Differentiation

The Role of Notch in Endothelial Cell-Mediated Protection of AML Precursors from Targeted Therapy

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Expression of the Human Alpha-Globin Cluster in the Absence of the Major Regulatory Element Mcs-R2

Potent and Timed Epigenetic Repression of PD-1 in Human T Cells

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

DNA Methylation Identifies Genetically and Prognostically Distinct Subtypes of MDS

NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling

Epigenetic Control of Foxp3, CAMTA1 and FUT7 Genes in Human Regulatory T Cells

Genome-Wide Analysis of the Regulatory Landscape in Different Pre-B-ALL Subtypes

Comparison of Fetal and Adult Erythroid Chromosomal Architectures Identifies a Novel Fetal Hemoglobin Regulatory Region

GWAS of Complete Blood Count (CBC) Measures in 13,403 Blood Donors in the Multi-Racial RBC-Omics Study Reveal Novel Genetic Loci in Minority Populations Which Provide Insights into the Pathways That May Connect Them to Disease

Systematic Assessment of GATA2 Genetic Variation Reveals the Presence of Novel Disease-Causing Synonymous Exonic Mutations

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

The -2518A/G (rs1026411) Regulatory Region Polymorphism of the Monocyte Chemoattractant Protein-1 (MCP-1) Is Associated with Secondary Myelofibrosis

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function

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American Society of Hematology

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ASH Publications

American Society of Hematology

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