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Journal Articles

Hyperstable SGK1 steps out of AKT’s shadow

Franziska Gehringer, Alexey Ushmorov
Journal: Blood
Blood (2021) 138 (11): 917–918.
DOI: https://doi.org/10.1182/blood.2021012518
Published: 2021
Journal Articles

SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence

Brief Report
Jie Gao, Eirini Sidiropoulou, Ieuan Walker, Joanna A. Krupka, Karol Mizielinski, Zelvera Usheva, Shamith A. Samarajiwa, Daniel J. Hodson
Journal: Blood
Blood (2021) 138 (11): 959–964.
DOI: https://doi.org/10.1182/blood.2020010432
Published: 2021
Includes: Supplemental data
Journal Articles

Coding and noncoding drivers of mantle cell lymphoma identified through exome and genome sequencing

Prasath Pararajalingam, Krysta M. Coyle, Sarah E. Arthur, Nicole Thomas, Miguel Alcaide, Barbara Meissner, Merrill Boyle, Quratulain Qureshi, Bruno M. Grande, Christopher Rushton, Graham W. Slack, Andrew J. Mungall, Constantine S. Tam, Rishu Agarwal, Sarah-Jane Dawson, Georg Lenz, Sriram Balasubramanian, Randy D. Gascoyne, Christian Steidl, Joseph Connors, Diego Villa, Timothy E. Audas, Marco A. Marra, Nathalie A. Johnson, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2020) 136 (5): 572–584.
DOI: https://doi.org/10.1182/blood.2019002385
Published: 2020
Includes: Supplemental data
Journal Articles

Pipeline for Discovering Neoepitopes Generated By Alternative Splicing in B-ALL

Sisi Zheng, MD, Ammar S. Naqvi, PhD, Elisabeth Bolton-Gillespie, Mukta Asnani, Katharina Hayer, Yoseph Barash, PhD, Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1342.
DOI: https://doi.org/10.1182/blood-2019-131277
Published: 2019
Journal Articles

Long-Term Efficacy and Safety of Copanlisib in Multiply Relapsed or Refractory Patients with Marginal Zone Lymphoma

Martin Dreyling, MD, Panayiotis Panayiotidis, MD, George A Follows, MD PhD, Luigina Mollica, MD FRCPC, PhD, Arnon Nagler, MD MSc, Muhit Özcan, MD, Armando Santoro, Don Stevens, MD, David Trevarthen, MD, Florian Hiemeyer, MSc, Li Liu, PhD, Jose Garcia-Vargas, MD, Barrett H Childs, MD, Pier Luigi Zinzani, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1531.
DOI: https://doi.org/10.1182/blood-2019-121932
Published: 2019
Journal Articles

Identification of GPAT1 As a Novel Therapeutic Target for Acute Leukemia By Inhibiting Leukemia Specific Metabolism

Hidetoshi Irifune, MD, Yu Kochi, MD, Masayasu Hayashi, MD PhD, Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1384.
DOI: https://doi.org/10.1182/blood-2019-125661
Published: 2019
Journal Articles

Rive-CLL: Phase 1 Trial of Rituximab, Idelalisib, and Venetoclax in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia

John McKay, DO, Taha Al-Juhaishi, MD, Lai Guanhua, MD PhD, Maciej Kmieciak, PhD, Roy Sabo, PhD, Ariel Sindel, DO, Victor Yazbeck, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5482.
DOI: https://doi.org/10.1182/blood-2019-126335
Published: 2019
Journal Articles

Idelalisib for Relapsed/Refractory Follicular Lymphoma: Retrospective Study from Spanish Lymphoma Group Geltamo (GELT-IDE-2018-02)

Juan-Manuel Sancho, MD PhD, Olga García, Pablo Mozas, Santiago Mercadal, MD, Eva Donato, MD, Ana Muntañola Prat, MD, Javier Lopez Jimenez, MD, Pascual Fernandez Abellan, PhD, Jose-Angel Hernandez, MD, Maria J. Rodriguez-Salazar, MD, Samuel Romero, MD, Ana Marin Niebla, PhD, Angel Ramirez Payer, Raul Cordoba, MD PhD, Jose Luis Bello, MD, Beatriz Cuevas, MD, Itziar Oiartzabal, MD, Alejandro Martín, MD PhD, Jose Javier Sanchez Blanco, Nicholas Kelleher, MD, Ana Lafuente, MD, Marc Sorigué, MD, López Guillermo Armando, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5249.
DOI: https://doi.org/10.1182/blood-2019-125921
Published: 2019
Journal Articles

Risk of Serious Adverse Events, Infection and Sepsis in Patients with Relapsed and Refractory Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma Treated with Idelalisib

Jonathan Kopel, BS, Sriman Swarup, MDMBBS, Anita Sultan, MD, Lukman Tijani, MD, Ei Moe Phyu, MD, Myint Aung Win, MDMBBS, Thura Win Htut, MBBS, MRCP, Ye Aung, Akshar Dash, Myat Min Han, MD, Yin Mon Myat, MD, Donald P. Quick, MD, Nicholas D'Cunha, MD, Kyaw Zin Thein, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 5489.
DOI: https://doi.org/10.1182/blood-2019-123179
Published: 2019
Journal Articles

Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model

Kosinsky Yuri, PhD, Lulu Chu, PhD, Millie Shah, PhD, Karthick Vishwanathan, PhD, Connie Larsson, PhD, Andrew Bloecher, PhD, Brandon Willis, PhD, Hannah Dry, BSc, Kirill Peskov, PhD, Joseph Ware, PhD, Andrew Mortlock, PhD, Gabriel Helmlinger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5304.
DOI: https://doi.org/10.1182/blood-2019-130879
Published: 2019
Journal Articles

The Biological and Clinical Implications of the Alternative Splicing Landscape of 1,258 Myeloid Neoplasm Cases

Courtney E Hershberger, BS, Devlin C Moyer, BS, Wencke Walter, PhD, Stephan Hutter, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Richard A Padgett, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 769.
DOI: https://doi.org/10.1182/blood-2019-128278
Published: 2019
Journal Articles

Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias

Daichi Inoue, MD PhD, Stanley C Lee, PhD, Akihide Yoshimi, MD PhD, Justin Taylor, MD, Lillian E Bitner, BSc, Atsushi Tanaka, MD, Yasutaka Hayashi, MD PhD, Hana Cho, MSc, Chie Fukui, Ruth Saganty, Alexander V Penson, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 917.
DOI: https://doi.org/10.1182/blood-2019-124722
Published: 2019
Journal Articles

Prediction of Patients at Risk of CD19 Neg Relapse Following CD19-Directed CAR T Cell Therapy in B Cell Precursor Acute Lymphoblastic Leukemia

Pablo Domizi, PhD, Astraea Jager, BS, Jolanda Sarno, PhD, Charles G. Mullighan, MBBS, MD, Stephan Grupp, MD PhD, Elena Sotillo, PhD, David M. Barrett, Kara L. Davis, DO
Journal: Blood
Blood (2019) 134 (Supplement_1): 749.
DOI: https://doi.org/10.1182/blood-2019-128883
Published: 2019
Journal Articles

Genetic Analysis in the Tanzania Sickle Surveillance Study (TS3): Modifiers of Sickle Cell Disease and Identification of Hemoglobin Variants

Luke R. Smart, MD, Emmanuela E. Ambrose, MD, Mwesige Charles, BScHLS, Arielle G. Hernandez, MPH, Teresa S. Latham, MA, Adolfine Hokororo, MD MMed, MSc, Medard Beyanga, BLS, MSc, Erasmus Kamugisha, MD MSc, PhD, Erius Tebuka, MD MMed, Thad A. Howard, MS, Russell E. Ware, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 988.
DOI: https://doi.org/10.1182/blood-2019-128554
Published: 2019
Journal Articles

PF-114: A 4 th Generation Tyrosine Kinase-Inhibitor for Chronic Phase Chronic Myeloid Leukaemia Including BCRABL1 T315I

Anna G. Turkina, Prof., MD, Olga Vinogradova, MD PhD, Elza Lomaia, MD PhD, Evgeniya Shatokhina, MD PhD, Oleg A. Shukhov, MD PhD, Ekaterina Yu. Chelysheva, MD PhD, Dzhariyat Shikhbabaeva, Irina Nemchenko, MD PhD, Anna Petrova, MD, Anastasiya Bykova, MD, Andrey Zaritskey, MD PhD, Nadia Siordia, MD, Vasily Shuvaev, MD, Jorge E. Cortes, MD, Robert Peter Gale, Michele Baccarani, MD, Oliver Ottmann, Prof, MD, Ilya Mikhailov, Fedor Novikov, PhD, Veronika Shulgina, PhD MD, Ghermes Chilov, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1638.
DOI: https://doi.org/10.1182/blood-2019-127951
Published: 2019
Journal Articles

Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome

Nevin Yusufova, Matthew R Teater, PhD, Alexey Soshnev, Andreas Kloetgen, Adewola Osunsade, Joseph Conway, Ashley Doane, Arthur Skoultchi, Aristotelis Tsirigos, PhD, Yael David, C. David Allis, PhD, Ethel Cesarman, MD PhD, Ari Melnick, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 23.
DOI: https://doi.org/10.1182/blood-2019-127774
Published: 2019
Journal Articles

A Novel Recurrent Gain-of-Function Mutation of Rltpr Q575E in Adult T Cell Leukemia/Lymphoma

Yuichiro Uchida, Makoto Yoshimitsu, MD PhD, Yuhei Kamada, MD PhD, Naosuke Arima, MD, Kenji Ishitsuka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1489.
DOI: https://doi.org/10.1182/blood-2019-124641
Published: 2019
Journal Articles

A Proteomic Atlas of Cardiac Amyloidosis

Taxiarchis Kourelis, MD, Surendra Dasari, PhD, Ahmed U Fayyaz, MD, Martha Grogan, Marina Ramirez-Alvarado, Margaret Redfield, Omar F. abou Ezzeddine, MD, C.M., M.S., Angela Dispenzieri, MD, Ellen D. McPhail, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1790.
DOI: https://doi.org/10.1182/blood-2019-124802
Published: 2019
Journal Articles

Overcoming the Supportive Stroma-Induced Proliferation in Waldenstrom's Macroglobulinemia By Selective Inhibition of the FGF/FGF-Receptor Axis

Cinzia Federico, PhD, Antonio Sacco, RN, Katia Todoerti, PhD, Arianna Giacomini, PhD, Gaia C Ghedini, PhD, Gaetana Lanzi, PhD, Marina Motta, MD, Antonella Anastasia, MD, Vanessa Favasuli, Roberto Ronca, PhD, Silvia Giliani, PhD, Nicole Bozza, PhD, Riccardo Castelli, PhD, Giuseppe Rossi, Antonino Neri, MD, Marco Mor, PhD, Marco Presta, PhD, Aldo M. Roccaro, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1822.
DOI: https://doi.org/10.1182/blood-2019-126554
Published: 2019
Journal Articles

A Multicentre, Retrospective Observational Study to Evaluate the Clinical Outcomes of Patients with Chronic Lymphocytic Leukaemia (CLL) Treated with Idelalisib and Rituximab in the UK (RETRO-idel) - a Cohort of 110 Patients

Toby A. Eyre, Gavin Preston, MD, Huseini Hatimbhai Kagdi, MD PhD MBBS, FRCPath, MRCP, Amin Islam, MD, Toby Nicholson, FRCPath, MBBS, MRCP, BA, Christopher Fegan, MB, MD FRCP, FRCPath, Harry W Smith, BSc, MSc, Adam P Cursley, MSc, Heribert Ramroth, PhD, Nishan Rajakumaraswamy, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1762.
DOI: https://doi.org/10.1182/blood-2019-126845
Published: 2019