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Journal Articles

Occupy BTK: the key to controlling CLL

Philip A. Thompson
Journal: Blood
Blood (2020) 136 (1): 4–6.
DOI: https://doi.org/10.1182/blood.2020005877
Published: 2020
Journal Articles

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

Clinical Trials & Observations
Aileen G. Rowan, Richard Dillon, Aviva Witkover, Anat Melamed, Maria-Antonietta Demontis, Nicolas A. Gillet, Liew Jun Mun, Charles R. M. Bangham, Lucy B. Cook, Paul A. Fields, Graham P. Taylor
Journal: Blood
Blood (2020) 135 (23): 2023–2032.
DOI: https://doi.org/10.1182/blood.2019002665
Published: 2020
Includes: Supplemental data
Journal Articles

STAT1 Transcriptional Response Predicts Molecular Responses of PB-Derived Clonogenic Cells from MPN Patients to Interferon Alpha

Milena Kalmer, MSc, Kristina Feldberg, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, MD, Nicolas Chatain, Steffen Koschmieder
Journal: Blood
Blood (2019) 134 (Supplement_1): 1679.
DOI: https://doi.org/10.1182/blood-2019-122676
Published: 2019
Journal Articles

Potent Anti-Tumor Activity of Bcma CAR-T Therapy Against Heavily Treated Multiple Myeloma and Dynamics of Immune Cell Subsets Using Single-Cell Mass Cytometry

Yongxian Hu, MD, Zhang Yanlei, Guoqing Wei, Chang alex Hong, He Huang
Journal: Blood
Blood (2019) 134 (Supplement_1): 1859.
DOI: https://doi.org/10.1182/blood-2019-130341
Published: 2019
Journal Articles

XPO1 Mutations May Identify Binet Α Chronic Lymphocytic Leukemia Patients with Shorter Time to First Treatment

Riccardo Moia, MD, Chiara Favini, MSc, Sruthi Sagiraju, Valeria Spina, PhD, Alessio Bruscaggin, PhD, Silvia Rasi, Lorenzo De Paoli, Clara Deambrogi, PhD, Mattia Schipani, Ahad Ahmed Kodipad, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1743.
DOI: https://doi.org/10.1182/blood-2019-126054
Published: 2019
Journal Articles

Expansion of T Helper Cell Subsets in Chronic Lymphocytic Leukemia Cell Co-Cultures with Nurselike Cells

Alicia Vaca, PhD, Mariela Sivina, Karen Clise-Dwyer, PhD, Ekaterina Kim, MS, Michael J Keating, MBBS, Alessandra Ferrajoli, MD, William G. Wierda, MD PhD, Dan Li, PhD, Qing Ma, PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1746.
DOI: https://doi.org/10.1182/blood-2019-125827
Published: 2019
Journal Articles

CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immunomodulatory Activity Against Sensitive and Resistant Multiple Myeloma Cells

Antonia Lopez-Girona, Courtney G. Havens, Gang Lu, Emily Rychak, Derek Mendy, Bonny Gaffney, Christine Surka, Chin-Chun Lu, Mary Matyskiela, Gody Khambatta, Lilly Wong, Joshua Hansen, Daniel W. Pierce, Brian E. Cathers, James Carmichael
Journal: Blood
Blood (2019) 134 (Supplement_1): 1812.
DOI: https://doi.org/10.1182/blood-2019-124338
Published: 2019
Journal Articles

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

Ada Dona', PhD, Domenico Viola, Enrico Caserta, PhD, Francesca Besi, PhD, James F Sanchez, PhD, Guido Marcucci, MD, Jonathan J Keats, PhD, Amrita Y. Krishnan, MD, Matt Coffey, PhD, Douglas W. Sborov, MDMSc, Gerard Nuovo, MD, Craig C Hofmeister, MDMPH, Flavia Pichiorri, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1816.
DOI: https://doi.org/10.1182/blood-2019-128740
Published: 2019
Journal Articles

In Human Visualization of Ibrutinib-Induced CLL Compartment Shift

Marius E Mayerhoefer, Alexander Haug, Ulrich Jaeger, MD, Lukas Kazianka, MD, Verena Pichler, Sarah Pfaff, Hans-Jürgen Wester, PhD, Marcus Hacker, Philipp Bernhard Staber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1750.
DOI: https://doi.org/10.1182/blood-2019-131469
Published: 2019
Journal Articles

The Interaction of Tumor Cells and Myeloid-Derived Suppressor Cells in Chronic Myelogenous Leukemia

Hui Xu, Zunmin Zhu, Xiaojian Zhu, Na Shen, Shu Zhou, Yicheng Zhang
Journal: Blood
Blood (2019) 134 (Supplement_1): 1636.
DOI: https://doi.org/10.1182/blood-2019-125563
Published: 2019
Journal Articles

Accumulation of Endogenous DNA Damage Sustain Malignant Progression and Increase Therapy Resistance in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Evangelos Terpos, MD PhD, Nikhil C. Munshi, MD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1788.
DOI: https://doi.org/10.1182/blood-2019-123502
Published: 2019
Journal Articles

Targeting PRMT5 to Circumvent Acquired Ibrutinib Resistance in Mantle Cell Lymphoma

Shelby Sloan, BS, Fiona Brown, BS, JI Hyun Chung, PhD, Alexander Prouty, BS, Esther Wheeler, BS, Bonnie K Harrington, DVM, PhD, Eric Brooks, BS, Ayse S Yilmaz, MS, Hatice G Ozer, PhD, John C. Byrd, MD, Selina Chen-Kiang, PhD, Maurizio Di Liberto, PhD, Rosa Lapalombella, PhD, Kris Vaddi, PhD, Peggy Scherle, PhD, Youssef Youssef, MD, Robert A Baiocchi, MD PhD, Lapo Alinari, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4065.
DOI: https://doi.org/10.1182/blood-2019-128998
Published: 2019
Journal Articles

Phase I/II Study of Lenalidomide Combined with DA-EPOCH and Rituximab (DA-EPOCH-R 2 ) in Primary Effusion Lymphoma in Patients with or without HIV

Kathryn Lurain, MDMPH, Ramya Ramaswami, MBBS,MPH, Anaida Widell, RN, Irene Ekwede, RN, Jomy George, PharmD, Maryalice Stetler-Stevenson, MD PhD, Mark Raffeld, MD, Constance M. Yuan, MD PhD, Joseph Ziegelbauer, PhD, Frank Maldarelli, MD PhD, William D. Figg, PharmD, Cody Peer, PhD, Seth M. Steinberg, PhD, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4096.
DOI: https://doi.org/10.1182/blood-2019-122070
Published: 2019
Journal Articles

Duobody-CD3xCD20 Induces Potent Anti-Tumor Activity in Malignant Lymph Node B Cells from Patients with DLBCL, FL and MCL Ex Vivo , Irrespective of Prior Treatment with CD20 Monoclonal Antibodies

Hilma J Van Der Horst, MSc, A. Vera de Jonge, Ida H Hiemstra, PhD, Anne T Gelderloos, MSc, Daniella RAI Berry, Nathalie J Hijmering, Daphne de Jong, Prof Dr, Martine E.D. Chamuleau, Sonja Zweegman, MD PhD, Esther CW Breij, DPhil, Margaretha GM Roemer, PhD, Tuna Mutis
Journal: Blood
Blood (2019) 134 (Supplement_1): 4066.
DOI: https://doi.org/10.1182/blood-2019-125765
Published: 2019
Journal Articles

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Ipsita Pal, PhD, Yu Ri Kim, MD, Sohani Das Sharma, PhD, Prabhjot S. Mundi, MD, Andre M. Grilo, PhD, Luke E Berchowitz, PhD, Mingzhao Zhu, PhD, Hull G. Kenneth, PhD, Daniel Romo, PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4067.
DOI: https://doi.org/10.1182/blood-2019-131816
Published: 2019
Journal Articles

TNB-486, a Novel Fully Human Bispecific CD19 x CD3 Antibody That Kills CD19-Positive Tumor Cells with Minimal Cytokine Secretion

Harbani Malik, PhD, Ben Buelow, MD PhD, Udaya Rangaswamy, PhD, Aarti Balasubramani, Andrew Boudreau, Kevin Dang, Laura Davison, PhD, Shelley Force Aldred, Katherine Marie Harris, MD, Suhasini Iyer, PhD, Brett Jorgensen, PhD, Duy Pham, MBA, Kirthana Prabhakar, Ute Schellenberger, PhD, Harshad Ugamraj, Nathan Trinklein, PhD, Wim Van Schooten, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4070.
DOI: https://doi.org/10.1182/blood-2019-123226
Published: 2019
Journal Articles

A Multi-Center Dose-Finding Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Fimepinostat (CUDC-907) in Combination with Venetoclax in Patients with Relapsed/Refractory (R/R) Lymphoma

Anas Younes, MD, Connie Lee Batlevi, MD PhD, Jonathon B. Cohen, MDMS, Sven de Vos, MD PhD, Daniel J. Landsburg, MD, Zaw Win Myint, MD, Krish Patel, MD, Tycel J. Phillips, MD, Sonali M. Smith, MD, Jason R. Westin, MD, Anna W Ma, MS, Dena Grayson, MD PhD, Reinhard von Roemeling, MD, Stefan K. Barta, MD MRCP, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4104.
DOI: https://doi.org/10.1182/blood-2019-128857
Published: 2019
Journal Articles

Initial Findings of the Phase 1 Trial of PBCAR0191, a CD19 Targeted Allogeneic CAR-T Cell Therapy

Caron A. Jacobson, MD, Alex F. Herrera, MD, Lihua E Budde, MD PhD, Daniel J. DeAngelo, MD, Christopher Heery, MD, Anthony Stein, MD, Michael D. Jain, MD PhD, Bijal Shah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4107.
DOI: https://doi.org/10.1182/blood-2019-128203
Published: 2019
Journal Articles

Utilizing Multiparametric Flow Cytometry to Identify Patients with Primary Plasma Cell Leukemia at Diagnosis

Laura A Evans, Dragan Jevremovic, MD PhD, Bharat Nandakumar, Francis K. Buadi, MB, CHB, Angela Dispenzieri, MD, David Dingli, MD PhD, Martha Q. Lacy, MD, Suzanne R. Hayman, MD, Prashant Kapoor, MD, Ronald S. Go, MD, Nelson Leung, MD, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi L. Hwa, APRN, CNP, DNP, Eli Muchtar, MD, Rahma M Warsame, MD, Taxiarchis Kourelis, MD, Stephen J Russell, MD PhD, John A. Lust, MD PhD, Yi Lin, MD PhD, Mustaqeem Siddiqui, MD, Robert A. Kyle, MD, Morie A Gertz, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD, Wilson I Gonsalves, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4334.
DOI: https://doi.org/10.1182/blood-2019-126777
Published: 2019
Journal Articles

Simultaneous Inhibition of Mcl-1 and Induction of DNA Damage Accumulation By Chidamide, a Novel Selective HDACi, Potentiates the Cytotoxicity of ABT-199 in Acute Myeloid Leukemia

Bing Xu, Kai Chen, Qianying Yang, Jie Zha, Haijun Zhao, Liying Feng, Xiaolei Chen, Guo Fu, Ken H. Young, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5767.
DOI: https://doi.org/10.1182/blood-2019-121721
Published: 2019