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Journal Articles

Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ

Jan A Rath, MS, Gagan Bajwa, PhD, Benoit Carreres, MS, Isabelle Gruber, MS, Elisabeth Hoyer, BS, Meng-Fen Wu, MS, Yi-Ru Yu, PhD, Ping-Chih Ho, PhD, Malcolm K. Brenner, MD PhD, David Gfeller, PhD, Caroline Arber, MD

Blood (2019) 134 (Supplement_1): 250.

https://doi.org/10.1182/blood-2019-124714

Published: 2019

Journal Articles

Maria-I: A Deep-Learning Approach for Accurate Prediction of MHC Class I Tumor Neoantigen Presentation

Karan R. Kathuria, Binbin Chen, PhD, Michael S. Khodadoust, MD PhD, Niclas Olsson, PhD, Mark M Davis, PhD, Joshua E Elias, PhD, Ronald Levy, MD, Russ B. Altman, MD PhD, Arash A. Alizadeh, MD PhD

Blood (2019) 134 (Supplement_1): 84.

https://doi.org/10.1182/blood-2019-129334

Published: 2019

Journal Articles

Targeting Intracellular WT1 in AML Utilizing a T Cell Bispecific Antibody Construct: Augmenting Efficacy through Combination with Lenalidomide

Blood (2019) 134 (Supplement_1): 4450.

https://doi.org/10.1182/blood-2019-130121

Published: 2019

Journal Articles

Treg Downregulation Was Associated with Augmentation of T Cell Responses Against Immunogenic Antigens and Clinical Responses in Patients with Hematological Malignancies after Donor Lymphocyte Infusion (DLI)

Jochen Greiner, Marlies Götz, Michael Schmitt, MD PhD, Hartmut Döhner, MD, Markus Wiesneth, MD, Donald Bunjes, MD, Susanne Hofmann, MD

Blood (2018) 132 (Supplement 1): 3423.

https://doi.org/10.1182/blood-2018-99-111783

Published: 2018

Journal Articles

Identification of Specificity Groups in Myeloma Patients T Cell Receptor (TCR) Repertoire through Single Cell TCR Sequencing

Paola Neri, MD, Ranjan Maity, PhD, Sylvia McCulloch, MD, Peter Duggan, MD, Victor Jimenez-Zepeda, MD, Jason Tay, MD, Nizar Bahlis, MD

Blood (2018) 132 (Supplement 1): 4459.

https://doi.org/10.1182/blood-2018-99-117482

Published: 2018

Journal Articles

Activation of T Cells Specific to Endogenous Retroviral Peptides: Possible Association with Clinical Response to Azacitidine in Myeloid Malignancies

Andreas Due Ørskov, Sunil Kumar Saini, Anne-Mette Bjerregaard, Hitoshi Otani, Staffan Holmberg, Jakob Werner Hansen, Marianne Bach Treppendahl, Anne Ortved Gang, Inge Høgh Dufva, Gangning Liang, Aron Charles Eklund, Peter A. Jones, Kirsten Grønbæk, Sine Reker Hadrup

Blood (2017) 130 (Supplement 1): 4243.

https://doi.org/10.1182/blood.V130.Suppl_1.4243.4243

Published: 2017

Journal Articles

FVIII Proteins with a Modified Immunodominant T-Cell Epitope Exhibit Reduced Immunogenicity and Normal Procoagulant Activity

Ruth A. Ettinger, PhD, Joseph A. Liberman, PhD, Devi Gunasekera, BSSM, Eddie A. James, PhD, Arthur R. Thompson, MD PhD, Kathleen P. Pratt, PhD

Blood (2017) 130 (Supplement 1): 179.

https://doi.org/10.1182/blood.V130.Suppl_1.179.179

Published: 2017

Journal Articles

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Dyantha I. Van Der Lee, BSc., Helena M. Bijen, MSc, Renate S. Hagedoorn, ing., Willy M. Honders, ing., Michel G.D. Kester, ing., Dirk M. van der Steen, ing., Arnoud H. de Ru, ing., Inge Jedema, PhD, Hendrik Veelken, MD PhD, Mirjam H.M. Heemskerk, PhD, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Marieke Griffioen, PhD

Blood (2017) 130 (Supplement 1): 168.

https://doi.org/10.1182/blood.V130.Suppl_1.168.168

Published: 2017

Journal Articles

Identification of Cross-Reactive Targets of TCR-Based Therapeutic Agents within the Human Proteome

Ron S Gejman, BA, Tao Dao, MDPhD, David A. Scheinberg, MDPhD

Blood (2017) 130 (Supplement 1): 3188.

https://doi.org/10.1182/blood.V130.Suppl_1.3188.3188

Published: 2017

Journal Articles

TCR-Ligand Dissociation-Rate, a Reliable and Determining Parameter, Identifying Tumor-Reactive CD8 T Cells of High Avidity and Functional Potency

Nathalie Rufer, PhD MD, Mathilde Allard, PhD, Barbara Couturaud, Laura Carretero, PhD, Julien Schmidt, PhD, Minh Ngoc Duong, PhD, Petra Baumgaertner, PhD, Philippe Gannon, PhD, Daniel Speiser, MD, Michael Hebeisen, PhD

Blood (2016) 128 (22): 5894.

https://doi.org/10.1182/blood.V128.22.5894.5894

Published: 2016

Journal Articles

Anti-FcRH5/CD3 T Cell Dependent Bispecific Antibody (TDB) for the Treatment of Multiple Myeloma

Blood (2016) 128 (22): 4475.

https://doi.org/10.1182/blood.V128.22.4475.4475

Published: 2016

Journal Articles

Targeting Epstein-Barr virus–transformed B lymphoblastoid cells using antibodies with T-cell receptor–like specificities

Junyun Lai, Wei Jian Tan, Chien Tei Too, Joanna Ai Ling Choo, Lan Hiong Wong, Fatimah Bte Mustafa, Nalini Srinivasan, Angeline Pei Chiew Lim, Youjia Zhong, Nicholas R. J. Gascoigne, Brendon J. Hanson, Soh Ha Chan, Jianzhu Chen, Paul A. MacAry

Blood (2016) 128 (10): 1396–1407.

https://doi.org/10.1182/blood-2016-03-707836

Published: 2016

Includes: Supplemental data

Journal Articles

Modification of Predicted Inhibitor Risk in Non-Severe Hemophilia-a By in silico Analysis of Human Proteome Homology with Wild-Type, FVIII-Derived Peptides

Adrian Shepherd, PhD, Stuart Skelton, MSc, David Moss, PhD, Dan Hart, MBChB, PhD

Blood (2015) 126 (23): 290.

https://doi.org/10.1182/blood.V126.23.290.290

Published: 2015

Journal Articles

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Lorenz Jahn, Renate S. Hagedoorn, Pleun Hombrink, PhD, Michel G.D. Kester, Dirk M. van der Steen, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD

Blood (2015) 126 (23): 3002.

https://doi.org/10.1182/blood.V126.23.3002.3002

Published: 2015

Journal Articles

Immunotherapy with Chimeric Antigen Receptor Targeting Intracellular WT1 Gene Product Complexed with HLA-a*24:02 Molecule

Hiroaki Ikeda, MD PhD, Yasushi Akahori, PhD, Motohiro Yoneyama, Yuki Orito, Yoshihiro Miyahara, Yasunori Amaishi, Sachiko Okamoto, Junichi Mineno, PhD, Kazutoh Takesako, PhD, Hiroshi Fujiwara, MD PhD, Masaki Yasukawa, MD PhD, Hiroshi Shiku, MD PhD

Blood (2015) 126 (23): 4292.

https://doi.org/10.1182/blood.V126.23.4292.4292

Published: 2015

Journal Articles

Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma

Deepak Perumal, PhD, Alessandro Lagana', PhD, Alex Rubinsteyn, PhD, John P Finnigan, Jr., BS, Pei-Yu Kuo, MS, Violetta V Leshchenko, PhD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Jeff Hammerbacher, BA, Eric Schadt, PhD, Nina Bhardwaj, MD PhD, Samir Parekh, MD

Blood (2015) 126 (23): 1851.

https://doi.org/10.1182/blood.V126.23.1851.1851

Published: 2015

Journal Articles

PBMCs from Hemophilia a Subjects with and without an Inhibitor Show Robust Cytokine Secretion in Response to Factor VIII C2 Domain Epitopes

Devi Gunasekera, MBBS, Debargh Kumar Dutta, PhD, Eddie A. James, PhD, Margaret V Ragni, Kathleen P. Pratt, PhD

Blood (2015) 126 (23): 2291.

https://doi.org/10.1182/blood.V126.23.2291.2291

Published: 2015

Journal Articles

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients

Devi Gunasekera, Ruth A. Ettinger, Shelley Nakaya Fletcher, Eddie A. James, Maochang Liu, John C. Barrett, Janice Withycombe, Dana C. Matthews, Melinda S. Epstein, Richard J. Hughes, Kathleen P. Pratt

Blood (2015) 126 (7): 895–904.

https://doi.org/10.1182/blood-2014-09-599365

Published: 2015

Includes: Supplemental data

Journal Articles

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

Lorenz Jahn, Pleun Hombrink, Chopie Hassan, Michel G. D. Kester, Dirk M. van der Steen, Renate S. Hagedoorn, J. H. Frederik Falkenburg, Peter A. van Veelen, Mirjam H. M. Heemskerk

Blood (2015) 125 (6): 949–958.

https://doi.org/10.1182/blood-2014-07-587840

Published: 2015

Includes: Supplemental data

Journal Articles

Molecular Dynamics As a Computational Tool to Study the Immune Reactivity: Identification of Conformational Changes in the Major Histocompatibility Complex

Estefania Garcia Guerrero, Jose Antonio Pérez Simon, Luis Ignacio Sánchez Abarca, Irene Diaz Moreno, Miguel Angel De la rosa, Antonio Diaz Quintana

Blood (2014) 124 (21): 2735.

https://doi.org/10.1182/blood.V124.21.2735.2735

Published: 2014

NARROW

Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ

Maria-I: A Deep-Learning Approach for Accurate Prediction of MHC Class I Tumor Neoantigen Presentation

Targeting Intracellular WT1 in AML Utilizing a T Cell Bispecific Antibody Construct: Augmenting Efficacy through Combination with Lenalidomide

Treg Downregulation Was Associated with Augmentation of T Cell Responses Against Immunogenic Antigens and Clinical Responses in Patients with Hematological Malignancies after Donor Lymphocyte Infusion (DLI)

Identification of Specificity Groups in Myeloma Patients T Cell Receptor (TCR) Repertoire through Single Cell TCR Sequencing

Activation of T Cells Specific to Endogenous Retroviral Peptides: Possible Association with Clinical Response to Azacitidine in Myeloid Malignancies

FVIII Proteins with a Modified Immunodominant T-Cell Epitope Exhibit Reduced Immunogenicity and Normal Procoagulant Activity

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Identification of Cross-Reactive Targets of TCR-Based Therapeutic Agents within the Human Proteome

TCR-Ligand Dissociation-Rate, a Reliable and Determining Parameter, Identifying Tumor-Reactive CD8 T Cells of High Avidity and Functional Potency

Anti-FcRH5/CD3 T Cell Dependent Bispecific Antibody (TDB) for the Treatment of Multiple Myeloma

Targeting Epstein-Barr virus–transformed B lymphoblastoid cells using antibodies with T-cell receptor–like specificities

Modification of Predicted Inhibitor Risk in Non-Severe Hemophilia-a By in silico Analysis of Human Proteome Homology with Wild-Type, FVIII-Derived Peptides

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Immunotherapy with Chimeric Antigen Receptor Targeting Intracellular WT1 Gene Product Complexed with HLA-a*24:02 Molecule

Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma

PBMCs from Hemophilia a Subjects with and without an Inhibitor Show Robust Cytokine Secretion in Response to Factor VIII C2 Domain Epitopes

Factor VIII gene variants and inhibitor risk in African American hemophilia A patients

Therapeutic targeting of the BCR-associated protein CD79b in a TCR-based approach is hampered by aberrant expression of CD79b

Molecular Dynamics As a Computational Tool to Study the Immune Reactivity: Identification of Conformational Changes in the Major Histocompatibility Complex

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American Society of Hematology

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American Society of Hematology

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