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Journal Articles

Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment

Min Xiao, Wuju Zhang, Wen Liu, Linlin Mao, Jincheng Yang, Le Hu, Sheng Zhang, Yaling Zheng, Anling Liu, Qiancheng Song, Yuhua Li, Guozhi Xiao, Zhipeng Zou, Xiaochun Bai

Blood (2021) 137 (25): 3533–3547.

https://doi.org/10.1182/blood.2020007731

Published: 2021

Includes: Supplemental data

Journal Articles

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Shinichi Ishii, Tomohide Suzuki, Kanako Wakahashi, Noboru Asada, Yuko Kawano, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Yukio Nakamura, Seiya Mizuno, Satoru Takahashi, Toshimitsu Matsui, Yoshio Katayama

Blood (2021) 137 (11): 1457–1467.

https://doi.org/10.1182/blood.2020007172

Published: 2021

Includes: Supplemental data

Journal Articles

Changes in the Main Bone Marrow Cell Subpopulations May Potentially Contribute to the Initiation of Acute Myeloid Leukemia

Shlomit Yehudai-Reshef, PhD, Rawan Sabah, Tal Gabay, Tsila Zuckerman, MD

Blood (2019) 134 (Supplement_1): 2494.

https://doi.org/10.1182/blood-2019-128097

Published: 2019

Journal Articles

Expansion of Human Mesenchymal Stromal/Stem Cells Using Standardized Xeno-Free, Serum-Free Culture Condition

Van T. Hoang, PhD, Quynh-Mai Trinh, M.Sc., Phuong TM Dam, PhD, Yen-Nhi Phung, M.Sc., Ngan T.H. Nguyen, Hong-Hue Bui, Minh-Hang Le, M.Sc., Hong-Nhung Trinh, M.Sc., Tuyet-Anh T. Nguyen, M.Sc., Minh Duc Hoang, PhD, Nguyen Thanh Liem, MD, PhD

Blood (2019) 134 (Supplement_1): 3253.

https://doi.org/10.1182/blood-2019-132140

Published: 2019

Journal Articles

Myeloma bone disease: from biology findings to treatment approaches

Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Meletios A. Dimopoulos

Blood (2019) 133 (14): 1534–1539.

https://doi.org/10.1182/blood-2018-11-852459

Published: 2019

Journal Articles

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Rosemary Soucy, Ka Tat Siu, PhD, Kenta Mukaihara, MD PhD, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 4476.

https://doi.org/10.1182/blood-2018-99-118377

Published: 2018

Journal Articles

Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Bin Yuan, Stanley Ly, Khoa Nguyen, Vivien Tran, Kiersten Maldonado, Charles Kinglsey, Jared K Burks, PhD, Xin Zhou, PhD, Benoit deCrombrugghe, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD

Blood (2018) 132 (Supplement 1): 86.

https://doi.org/10.1182/blood-2018-99-117258

Published: 2018

Journal Articles

Protein Kinase CSNK1A Regulates the Multiple Myeloma Plasma Cell-Microenvironment Interplay

Sabrina Manni, PhD, Ketty Gianesin, PhD, Marilena Carrino, PhD, Federica Costa, PhD, Gregorio Barilà, MD, Renato Zambello, MD, Nicola Giuliani, MD PhD, Livio Trentin, MD, Gianpietro Semenzato, MD, Francesco Piazza, MD

Blood (2017) 130 (Supplement 1): 4398.

https://doi.org/10.1182/blood.V130.Suppl_1.4398.4398

Published: 2017

Journal Articles

The Effect of 5-Azacitidine Treatment on the Biologic Characteristics of Bone Marrow Mesenchymal Stem Cells in Patients with Myelodysplastic Syndromes

Ioannis Liapis, Aristea Batsali, Anastasios Mitrakos, Elisavet Kouvidi, Athanasios Galanopoulos, MD PhD, Charalampos Pontikoglou, MD PhD, Emmanouil Kanavakis, Helen A. Papadaki, MD PhD

Blood (2017) 130 (Supplement 1): 4242.

https://doi.org/10.1182/blood.V130.Suppl_1.4242.4242

Published: 2017

Journal Articles

Bone-Targeted Pharmacological Inhibition of Notch Signaling As a Novel Approach to Inhibit Myeloma Growth and Bone Destruction

Jesus Delgado-Calle, PhD, Gerald Wu, Jessica Nelson, Emily G Atkinson, Kevin McAndrews, Lifeng Xiao, Frank H Ebetino, Robert K Boeckman, Jr., David David Roodman, MD PhD, Teresita Bellido

Blood (2017) 130 (Supplement 1): 4419.

https://doi.org/10.1182/blood.V130.Suppl_1.4419.4419

Published: 2017

Journal Articles

Aplidin (Plitidepsin) Regulates Viability and Function of Myeloma Cells and Bone Cells in Combination with Other Anti-MM Drugs

Jesus Delgado-Calle, PhD, Emily G Atkinson, Jessica Nelson, Noriyoshi Kurihara, DDS, PhD, Carlos Galmarini, David David Roodman, MD PhD, Teresita Bellido

Blood (2017) 130 (Supplement 1): 3065.

https://doi.org/10.1182/blood.V130.Suppl_1.3065.3065

Published: 2017

Journal Articles

Role of Sclerostin in Multiple Myeloma Progression

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Ka Tat Siu, PhD, Peter Wang, BS, Noopur Raje, MD

Blood (2017) 130 (Supplement 1): 4341.

https://doi.org/10.1182/blood.V130.Suppl_1.4341.4341

Published: 2017

Journal Articles

Targeted Remodeling of the Tumor Microenvironment Via Mechanical Stimulation Defines a Novel Therapeutic Strategy in Myeloma Bone Disease

Fani Ziouti, Maximilian Rummler, Anne Seliger, Andreas Brandl, PhD, Andreas Beilhack, MD, Bjarne Bogen, MD PhD, Maureen Lynch, PhD, Franz Jakob, MD, Regina Ebert, PhD, Bettina Willie, PhD, Franziska Jundt, MD

Blood (2017) 130 (Supplement 1): 1778.

https://doi.org/10.1182/blood.V130.Suppl_1.1778.1778

Published: 2017

Journal Articles

The Tmprss6 -/- Mouse Model of Iron Refractory Iron Deficiency Anemia (IRIDA) Exhibits Disrupted Phosphate Homeostasis, Elevated Circulating FGF23 Levels, and Increased Fgf23 Expression in Bone Marrow

Xiuqi Li, BS, Larisa Lozovatsky, MS, Abitha Sukumaran, PhD, Steven Tommasini, PhD, Jackie A. Fretz, PhD, Karin E. Finberg, MD PhD

Blood (2017) 130 (Supplement 1): 228.

https://doi.org/10.1182/blood.V130.Suppl_1.228.228

Published: 2017

Journal Articles

Bone Marrow Stromal Cells Induce ALDH+ Stem Cell Phenotype and Chemotherapy Resistance in AML Cells through TGF-β1 Mediated Signaling: Reversal By TGFβ Inhibitor Galunisertib

Ximin Zhou, Bin Yuan, Yuanqing Yan, Khoa Nguyen, Vivian Ruvolo, PhD, Hong Mu, MD PhD, Teresa McQueen, MS, Elizabeth J Shpall, MD, Kim-Ann Do, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD

Blood (2017) 130 (Supplement 1): 1163.

https://doi.org/10.1182/blood.V130.Suppl_1.1163.1163

Published: 2017

Journal Articles

Apoptotic Osteocytes Promote Myeloma Dissemination to New Bone Sites Via Suppression of Immune Surveillance in Bone Marrow

Xiaoxiao Hao, Ru Feng, MD, Timothy Trotter, Pramod Gowda, Mary Fok, Xiaoxuan Xu, Denise Peker, MD, Amjad Javed, Yang Yang, MD

Blood (2017) 130 (Supplement 1): 125.

https://doi.org/10.1182/blood.V130.Suppl_1.125.125

Published: 2017

Journal Articles

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

Blood (2017) 129 (26): 3452–3464.

https://doi.org/10.1182/blood-2017-03-773341

Published: 2017

Includes: Supplemental data

Journal Articles

Genetic Sost Deletion and Pharmacological Inhibition of Sclerostin Prevent Multiple Myeloma-Induced Bone Loss without Affecting Tumor Growth

Jesus Delgado-Calle, PhD, Judith Anderson, Meloney D. Cregor, Dan Zhou, Lilian I. Plotkin, PhD, Teresita M. Bellido, PhD, G. David Roodman, MD PhD

Blood (2016) 128 (22): 1136.

https://doi.org/10.1182/blood.V128.22.1136.1136

Published: 2016

Journal Articles

Osteocyte Apoptosis Attracts Myeloma Cells to Bone and Supports Progression through Regulation of the Bone Marrow Microenvironment

Timothy N. Trotter, Mary Fok, Justin T. Gibson, Deniz Peker, MD, Amjad Javed, MSc, PhD, Yang Yang, MD PhD

Blood (2016) 128 (22): 484.

https://doi.org/10.1182/blood.V128.22.484.484

Published: 2016

Journal Articles

Regulation of Osteoblast Function in Myeloma Bone Disease By Semaphorin 4D

Attaya Suvannasankha, MD, Colin D Crean, Douglas R Tompkins, Jesus Delgado-Calle, PhD, Teresita M Bellido, PhD, G. David Roodman, MD PhD, John M Chirgwin, PhD

Blood (2016) 128 (22): 4439.

https://doi.org/10.1182/blood.V128.22.4439.4439

Published: 2016

NARROW

Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Changes in the Main Bone Marrow Cell Subpopulations May Potentially Contribute to the Initiation of Acute Myeloid Leukemia

Expansion of Human Mesenchymal Stromal/Stem Cells Using Standardized Xeno-Free, Serum-Free Culture Condition

Myeloma bone disease: from biology findings to treatment approaches

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Protein Kinase CSNK1A Regulates the Multiple Myeloma Plasma Cell-Microenvironment Interplay

The Effect of 5-Azacitidine Treatment on the Biologic Characteristics of Bone Marrow Mesenchymal Stem Cells in Patients with Myelodysplastic Syndromes

Bone-Targeted Pharmacological Inhibition of Notch Signaling As a Novel Approach to Inhibit Myeloma Growth and Bone Destruction

Aplidin (Plitidepsin) Regulates Viability and Function of Myeloma Cells and Bone Cells in Combination with Other Anti-MM Drugs

Role of Sclerostin in Multiple Myeloma Progression

Targeted Remodeling of the Tumor Microenvironment Via Mechanical Stimulation Defines a Novel Therapeutic Strategy in Myeloma Bone Disease

The Tmprss6 -/- Mouse Model of Iron Refractory Iron Deficiency Anemia (IRIDA) Exhibits Disrupted Phosphate Homeostasis, Elevated Circulating FGF23 Levels, and Increased Fgf23 Expression in Bone Marrow

Bone Marrow Stromal Cells Induce ALDH+ Stem Cell Phenotype and Chemotherapy Resistance in AML Cells through TGF-β1 Mediated Signaling: Reversal By TGFβ Inhibitor Galunisertib

Apoptotic Osteocytes Promote Myeloma Dissemination to New Bone Sites Via Suppression of Immune Surveillance in Bone Marrow

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

Genetic Sost Deletion and Pharmacological Inhibition of Sclerostin Prevent Multiple Myeloma-Induced Bone Loss without Affecting Tumor Growth

Osteocyte Apoptosis Attracts Myeloma Cells to Bone and Supports Progression through Regulation of the Bone Marrow Microenvironment

Regulation of Osteoblast Function in Myeloma Bone Disease By Semaphorin 4D

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American Society of Hematology

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ASH Publications

American Society of Hematology

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