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Journal Articles

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

Blood (2020) 136 (4): 468–479.

DOI: https://doi.org/10.1182/blood.2019004147

Published: 2020

Includes: Supplemental data

Journal Articles

GPS2 promotes erythroid differentiation by control of the stability of EKLF protein

Wen-Bing Ma, Xiao-Han Wang, Chang-Yan Li, Huan-Huan Tian, Jie Zhang, Jun-Jie Bi, Guang-Ming Ren, Shou-Song Tao, Xian Liu, Wen Zhang, Dong-Xu Li, Hui Chen, Yi-Qun Zhan, Miao Yu, Chang-Hui Ge, Xiao-Ming Yang, Rong-Hua Yin

Blood (2020) 135 (25): 2302–2315.

DOI: https://doi.org/10.1182/blood.2019003867

Published: 2020

Includes: Supplemental data

Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker

Blood (2020) 135 (25): 2209–2210.

DOI: https://doi.org/10.1182/blood.2020005882

Published: 2020

Journal Articles

Single-Cell Pathway Enrichment and Regulatory Profiling of Multiple Myeloma across Disease Stages

Tianjiao Wang, BA, Hua Sun, PhD, Daniel Cui Zhou, BA, Ruiyang Liu, BS, Lijun Yao, MS, Mark A. Fiala, MSW, Daniel R. Kohnen, MBA, Julie O'Neal, PhD, Michael P. Rettig, PhD, Jared S Fowles, PhD, Stephen T. Oh, MD, Reyka G Jayasinghe, PhD, Ravi Vij, MBBS, John F. DiPersio, MD PhD, Li Ding, PhD

Blood (2019) 134 (Supplement_1): 364.

DOI: https://doi.org/10.1182/blood-2019-131361

Published: 2019

Journal Articles

DT2216, a BCL-XL Proteolysis Targeting Chimera (PROTAC), Is a Potent Anti T-Cell Lymphoma Agent That Does Not Induce Significant Thrombocytopenia

Yonghan He, MD, Raphael Koch, Vivekananda Budamagunta, Dongwen Lv, Sajid Khan, Xuan Zhang, Janet S Wiegand, Guangrong Zheng, David M. Weinstock, MD, Daohong Zhou

Blood (2019) 134 (Supplement_1): 303.

DOI: https://doi.org/10.1182/blood-2019-125820

Published: 2019

Journal Articles

Chaperone-Mediated Autophagy Ensures Hematopoietic Stem Cell Maintenance

Shuxian Dong, PhD, Britta Will, PhD, Ana Maria Cuervo, MD PhD

Blood (2019) 134 (Supplement_1): 272.

DOI: https://doi.org/10.1182/blood-2019-132230

Published: 2019

Journal Articles

A Comprehensive Analysis of Single-Cell Chromatin Accessibility and Gene Expression Identifies Intra-Tumor Heterogeneity and Molecular Treatment Responses in Relapsed/Refractory Multiple Myeloma

Blood (2019) 134 (Supplement_1): 575.

DOI: https://doi.org/10.1182/blood-2019-130051

Published: 2019

Journal Articles

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Kiwamu Hatakeyama, MD, Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 631.

DOI: https://doi.org/10.1182/blood-2019-125670

Published: 2019

Journal Articles

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Catherine Rondelli, Aiden Danoff, Hector Bergonia, Samantha Gillis, Julia Free, John D. Phillips, PhD, Yvette Y Yien, PhD

Blood (2019) 134 (Supplement_1): 427.

DOI: https://doi.org/10.1182/blood-2019-132039

Published: 2019

Journal Articles

Selective Dependency of MLL-Rearranged Leukemia on Immunoproteasome Function

Nuria Tubío Santamaría, Jonas Tönsing, Tina M. Schnoeder, PhD, Ulrike Seifert, Clemens Cammann, Juliane Mohr, PhD, Aniruddha J. Deshpande, PhD, Joanna Kirkpatrick, Alessandro Ori, PhD, Florian Perner, MD, Florian H. Heidel, MD

Blood (2019) 134 (Supplement_1): 529.

DOI: https://doi.org/10.1182/blood-2019-122100

Published: 2019

Journal Articles

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Ting Du, PhD, Yan Song, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD

Blood (2019) 134 (Supplement_1): 3074.

DOI: https://doi.org/10.1182/blood-2019-130236

Published: 2019

Journal Articles

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

Blood (2019) 134 (Supplement_1): 4142.

DOI: https://doi.org/10.1182/blood-2019-126500

Published: 2019

Journal Articles

MCL1 Inhibitors in Multiple Myeloma

Karin Vanderkerken, PhD, Kim De Veirman, Ken Maes, Eline Menu, PhD, Elke De Bruyne, PhD

Blood (2019) 134 (Supplement_1): SCI-12.

DOI: https://doi.org/10.1182/blood-2019-121104

Published: 2019

Journal Articles

Proteostasis and Myeloid Stem Cell Production

Robert Signer, PhD

Blood (2019) 134 (Supplement_1): SCI-42.

DOI: https://doi.org/10.1182/blood-2019-121085

Published: 2019

Journal Articles

Functional Interactions between Transcription Factors Involved in Myeloma Pathogenesis - Biological and Therapeutic Implications

Sondra L. Downey-Kopyscinski, PhD, Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD, Huihui Tang, PhD, Brian Glassner, PhD, Olga Dashevsky, PhD, Minasri Borah, Megan Bariteau, B.Sc., Richard Groen, John G Doench, PhD, Constantine S. Mitsiades, MD PhD

Blood (2019) 134 (Supplement_1): 315.

DOI: https://doi.org/10.1182/blood-2019-127502

Published: 2019

Journal Articles

Direct Phosphorylation and Stabilization of MYC By Aurora B Kinase Promotes T Cell Leukemogenesis

Hudan Liu, PhD, Jue Jiang, PhD, Jingchao Wang, PhD, Ming Yue, PhD, Hui Feng, MD PhD, Guoliang Qing, PhD

Blood (2019) 134 (Supplement_1): 732.

DOI: https://doi.org/10.1182/blood-2019-130112

Published: 2019

Journal Articles

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Ursula S.A. Stalmann, MD, Fabio Ticconi, MSc, Ronghui Li, MSc, Aaron B. Wong, PhD, Glenn Cowley, PhD, David E. Root, PhD, Dirk Heckl, PhD, Inge Snoeren, MSc, Sergio Martinez, PhDMSc, Tim H Brümmendorf, MD, Andreas Schuppert, PhD, Ivan Costa, PhD, Benjamin L. Ebert, MD PhD, Rebekka K. Schneider, MD PhD

Blood (2019) 134 (Supplement_1): 559.

DOI: https://doi.org/10.1182/blood-2019-122588

Published: 2019

Journal Articles

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

Taishi Yonezawa, MSc, Hirotaka Takahasi, PhD, Tatsuya Sawasaki, PhD, Toshio Kitamura, MD PhD, Susumu Goyama, MD PhD

Blood (2019) 134 (Supplement_1): 1252.

DOI: https://doi.org/10.1182/blood-2019-126264

Published: 2019

Journal Articles

Pharmacological Perturbation of the Immunoproteasome in Hematologic Neoplasias: Therapeutic Implications

Sondra L. Downey-Kopyscinski, PhD, Ricardo De Matos Simoes, PhD, Megan Bariteau, BSc, Minasri L. Borah, Sam Bender, Janaka Foneska, Jennifer Roth, Richard Groen, Gina Walter, Manja Friese-Hamim, Samantha M. Goodstal, Michael Sanderson, Constantine S. Mitsiades, MD PhD

Blood (2019) 134 (Supplement_1): 1291.

DOI: https://doi.org/10.1182/blood-2019-130356

Published: 2019

Journal Articles

Trial in Progress: Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma

Wilson I Gonsalves, MD, Srinivas Devarakonda, MD, Rachid Baz, MD, Natalia Neparidze, MD, Alex A Adjei, MD PhD, Charles Kunos, MD, Shaji K. Kumar, MD

Blood (2019) 134 (Supplement_1): 3160.

DOI: https://doi.org/10.1182/blood-2019-123399

Published: 2019

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NARROW

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

GPS2 promotes erythroid differentiation by control of the stability of EKLF protein

A master erythroid regulator gets its own GPS

Single-Cell Pathway Enrichment and Regulatory Profiling of Multiple Myeloma across Disease Stages

DT2216, a BCL-XL Proteolysis Targeting Chimera (PROTAC), Is a Potent Anti T-Cell Lymphoma Agent That Does Not Induce Significant Thrombocytopenia

Chaperone-Mediated Autophagy Ensures Hematopoietic Stem Cell Maintenance

A Comprehensive Analysis of Single-Cell Chromatin Accessibility and Gene Expression Identifies Intra-Tumor Heterogeneity and Molecular Treatment Responses in Relapsed/Refractory Multiple Myeloma

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Selective Dependency of MLL-Rearranged Leukemia on Immunoproteasome Function

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

MCL1 Inhibitors in Multiple Myeloma

Proteostasis and Myeloid Stem Cell Production

Functional Interactions between Transcription Factors Involved in Myeloma Pathogenesis - Biological and Therapeutic Implications

Direct Phosphorylation and Stabilization of MYC By Aurora B Kinase Promotes T Cell Leukemogenesis

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

Pharmacological Perturbation of the Immunoproteasome in Hematologic Neoplasias: Therapeutic Implications

Trial in Progress: Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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