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Journal Articles

Trimethylated H3K27, and Di- and Trimethylated H3K4 Proteomic Profiling Distinguishes Acute Lymphoid Leukemia (ALL) from Acute Myeloid Leukemia (AML) and Associates with Overall Survival and Tyrosine Kinase Inhibitor Sensitivity in Adult ALL

Anneke D. van Dijk, BS, Fieke W Hoff, BSc, Yihua Qiu, Mary Figueroa, BS, Joya Chandra, PhD, Elias Jabbour, MD, Eveline S. de Bont, MD PhD, Steven M. Kornblau, MD

Blood (2019) 134 (Supplement_1): 1460.

https://doi.org/10.1182/blood-2019-124960

Published: 2019

Journal Articles

Selinexor in Combination with Induction and Consolidation Therapy in Older Adults with AML Is Highly Active

Timothy S. Pardee, MD PhD, Kris C Wood, PhD, Kevin H Lin, BS, Justine Rutter, PhD, Mariaelena Pierobon, MD, Emanuel Petricoin, PhD, Susan Lyerly, P.A.-C., Sarah Dralle, NP, Megan Manuel, NP, Leslie Renee Ellis, MD, Dianna S. Howard, MD, Rupali Bhave, MD, Bayard L Powell, MD

Blood (2019) 134 (Supplement_1): 1388.

https://doi.org/10.1182/blood-2019-129413

Published: 2019

Journal Articles

Determine White Blood Cell Count (WBCC) Limits and ABL Ct Cut-Off with ABL Copy Number (CN) Calibration for the Xpert® BCR-ABL Ultra Assay

Huilin Wei, MD PhD, Krupa Shridhar, Gwo-Jen Day, PhD

Blood (2019) 134 (Supplement_1): 5367.

https://doi.org/10.1182/blood-2019-130899

Published: 2019

Journal Articles

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Devi Gunasekera, MBBS, Pooja Vir, PhD, Ahmad Faisal Karim, PhD, Margaret V. Ragni, MD MPH, Elizabeth P. Merricks, PhD, Timothy C. Nichols, MD, Kathleen P. Pratt, PhD

Blood (2019) 134 (Supplement_1): 630.

https://doi.org/10.1182/blood-2019-124880

Published: 2019

Journal Articles

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Kiwamu Hatakeyama, MD, Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 631.

https://doi.org/10.1182/blood-2019-125670

Published: 2019

Journal Articles

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Olukemi Amodu, PhD, Binal N. Shah, Subulade Ademola, PhD, Bamidele Tayo, PhD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 942.

https://doi.org/10.1182/blood-2019-132190

Published: 2019

Journal Articles

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Samuel Lessard, PhD, Pauline Rimmele, PhD, Hui Ling, PhD, Kevin Moran, MSc, Benjamin Vieira, BS, Yi-Dong Lin, PhD, Vu Hong, PhD, Andreas Reik, PhD, Denny Dang, Naoya Uchida, MD, John F. Tisdale, MD, Pablo Rendo, MD, Ahmed Daak, PhD, Alexandra Hicks, PhD

Blood (2019) 134 (Supplement_1): 974.

https://doi.org/10.1182/blood-2019-126048

Published: 2019

Journal Articles

Oncogene-Independent Adaptation of Pre-B Cell Receptor Signaling Confers Drug Resistance and Signaling Plasticity in Ph-like ALL

Christian Hurtz, PhD, Gerald Wertheim, MD, PhD, Joseph Patrick Loftus, BS, Daniel Blumenthal, PhD, Anne Lehman, Yong Li, Bryan Manning, Katherine D Cummins, BMBS, Janis K Burkhardt, PhD, Alexander E. Perl, MD, Martin Carroll, MD, Sarah K. Tasian, MD

Blood (2019) 134 (Supplement_1): 747.

https://doi.org/10.1182/blood-2019-123514

Published: 2019

Journal Articles

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Marina Jerebtsova, PhD, Xiaomei Niu, MD, Sharmin Diaz, NP, Namita Kumari, PhD, Sergei Nekhai, PhD

Blood (2019) 134 (Supplement_1): 979.

https://doi.org/10.1182/blood-2019-130741

Published: 2019

Journal Articles

Pharmacokinetics-Guided Dosing of Hydroxyurea Can Achieve Near-Pancellular Fetal Hemoglobin Expression in Sickle Cell Anemia: F-Cell Analysis As a Benchmark for Disease-Modifying Therapy

Charles T. Quinn, MD, Omar Niss, MD, Amanda Pfeiffer, Jennifer Korpik, Holly Bonar, Mary Reynaud, Russell E. Ware, MD PhD, Patrick T. McGann, MD

Blood (2019) 134 (Supplement_1): 892.

https://doi.org/10.1182/blood-2019-130414

Published: 2019

Journal Articles

SIX1 Transcription Factor Enhances Human Erythropoiesis Via GATA1

Michael Creed, MSc, Christian Eberly, Jevon Cutler, PhD, MinJung Kim, PhD, Akhilesh Pandey, MD PhD, Curt I Civin, MD, Tami J Kingsbury, PhD

Blood (2019) 134 (Supplement_1): 3503.

https://doi.org/10.1182/blood-2019-131203

Published: 2019

Journal Articles

Inflammageing of Hematopoietic Stem Cells Is Driven By IL-1

Larisa V. Kovtonyuk, PhD, Francisco Caiado, PhD, Emma Marie Caroline Slack, Prof. Dr., Hitoshi Takizawa, PhD, Markus G. Manz, Prof.Dr.MD

Blood (2019) 134 (Supplement_1): 819.

https://doi.org/10.1182/blood-2019-130361

Published: 2019

Journal Articles

Constitutively Activated STAT3 Induces the Expression of Gli1 in Chronic Lymphocytic Leukemia Cells

Uri Rozovski, MD, David M. Harris, PhD, Ping Li, PhD, Zhiming Liu, BS, Taghi Manshouri, PhD, Ivo Veletic, MD, Preetesh Jain, MBBS,MDDM,PhD, Alessandra Ferrajoli, MD, Jan A. Burger, MD PhD, Prithviraj Bose, MD, Philip A. Thompson, MBBS, Nitin Jain, MD, Srdan Verstovsek, MD PhD, William G. Wierda, MD PhD, Michael J Keating, MBBS, Zeev E. Estrov, MD

Blood (2019) 134 (Supplement_1): 3018.

https://doi.org/10.1182/blood-2019-124014

Published: 2019

Journal Articles

Virological and Immunological Monitoring of Human Cytomegalovirus (HCMV) Infection in Hematopoietic Stem Cell Transplantation Recipients (HSCTR)

Elisa Gabanti, Roberta Sciarra, MD, Oscar Borsani, MD, Giuseppe Gerna, Daniela Caldera, MD, Anna Amelia Colombo, MD, Emilio Paolo Alessandrino, MD, Paolo Bernasconi, MD, Daniele Lilleri

Blood (2019) 134 (Supplement_1): 4544.

https://doi.org/10.1182/blood-2019-129939

Published: 2019

Journal Articles

The Role of Antiviral Treatment in Hepatitis C Virus (HCV)-Driven Monoclonal Gammopathies

Alba Rodríguez García, María Linares, PhD, Nicolas Mennesson, Alfredo Pérez-Revilla, Ricardo Sanchez, PhD MD, Alejandra Leivas, PhD BS, MSc, Rafael Alonso Fernández, MD, Edith Bigot-Corbel, PhD, Sylvie Hermouet, Joaquin Martinez-Lopez, MD PhD

Blood (2019) 134 (Supplement_1): 5560.

https://doi.org/10.1182/blood-2019-126549

Published: 2019

Journal Articles

Expansion of Human Mesenchymal Stromal/Stem Cells Using Standardized Xeno-Free, Serum-Free Culture Condition

Van T. Hoang, PhD, Quynh-Mai Trinh, M.Sc., Phuong TM Dam, PhD, Yen-Nhi Phung, M.Sc., Ngan T.H. Nguyen, Hong-Hue Bui, Minh-Hang Le, M.Sc., Hong-Nhung Trinh, M.Sc., Tuyet-Anh T. Nguyen, M.Sc., Minh Duc Hoang, PhD, Nguyen Thanh Liem, MD, PhD

Blood (2019) 134 (Supplement_1): 3253.

https://doi.org/10.1182/blood-2019-132140

Published: 2019

Journal Articles

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia (AML)

Marius Bill, MD PhD, Aparna Pathmanathan, Malith Karunasiri, Changxian Shen, Matthew Burke, Parvathi Ranganathan, PhD, Dimitrios Papaioannou, MD, Nina C. Zitzer, DVM, Katiri Snyder, Allison LaRocco, Allison Walker, Zachary Brannan, Ansel P. Nalin, Aharon G. Freud, MD PhD, Mikhail Dikov, Xiaoli Zhang, PhD, Clara D. Bloomfield, MD, Ramiro Garzon, MD, Adrienne M. Dorrance, PhD

Blood (2019) 134 (Supplement_1): 2546.

https://doi.org/10.1182/blood-2019-131856

Published: 2019

Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, Boaz Nachmias, MD PhD, Jordan M Chin, Fieke W Hoff, BSc, Kerstin Kaufmann, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Neil MacLean, Xiaoming Wang, Veronique Voisin, PhD, Aaron Botham, Andrea Arruda, Mark D. Minden, MD PhD, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD, Aaron D Schimmer, MD PhD

Blood (2019) 134 (Supplement_1): 2532.

https://doi.org/10.1182/blood-2019-123121

Published: 2019

Journal Articles

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Moua Yang, PhD, Calvin Harberg, Wenjing Chen, Sarah L. Wynia-Smith, PhD, Kate S. Carroll, PhD, Jacek Zielonka, PhD, Roy L. Silverstein, MD, Brian C. Smith, PhD

Blood (2019) 134 (Supplement_1): 2338.

https://doi.org/10.1182/blood-2019-122465

Published: 2019

Journal Articles

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

Caroline Busch, BSc, MSc, Chloe Gulliver, BSc, MSc, Theresa Mulholland, BSc, Michele Zagnoni, BSc, MSc, PhD, Catherine C. Berry, BSc,PhD, Helen Wheadon, BSc, PhD

Blood (2019) 134 (Supplement_1): 3732.

https://doi.org/10.1182/blood-2019-123967

Published: 2019

NARROW

Trimethylated H3K27, and Di- and Trimethylated H3K4 Proteomic Profiling Distinguishes Acute Lymphoid Leukemia (ALL) from Acute Myeloid Leukemia (AML) and Associates with Overall Survival and Tyrosine Kinase Inhibitor Sensitivity in Adult ALL

Selinexor in Combination with Induction and Consolidation Therapy in Older Adults with AML Is Highly Active

Determine White Blood Cell Count (WBCC) Limits and ABL Ct Cut-Off with ABL Copy Number (CN) Calibration for the Xpert® BCR-ABL Ultra Assay

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Oncogene-Independent Adaptation of Pre-B Cell Receptor Signaling Confers Drug Resistance and Signaling Plasticity in Ph-like ALL

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Pharmacokinetics-Guided Dosing of Hydroxyurea Can Achieve Near-Pancellular Fetal Hemoglobin Expression in Sickle Cell Anemia: F-Cell Analysis As a Benchmark for Disease-Modifying Therapy

SIX1 Transcription Factor Enhances Human Erythropoiesis Via GATA1

Inflammageing of Hematopoietic Stem Cells Is Driven By IL-1

Constitutively Activated STAT3 Induces the Expression of Gli1 in Chronic Lymphocytic Leukemia Cells

Virological and Immunological Monitoring of Human Cytomegalovirus (HCMV) Infection in Hematopoietic Stem Cell Transplantation Recipients (HSCTR)

The Role of Antiviral Treatment in Hepatitis C Virus (HCV)-Driven Monoclonal Gammopathies

Expansion of Human Mesenchymal Stromal/Stem Cells Using Standardized Xeno-Free, Serum-Free Culture Condition

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia (AML)

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

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American Society of Hematology

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American Society of Hematology

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