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Journal Articles

The characterization of distinct populations of murine skeletal cells that have different roles in B lymphopoiesis

Alanna C. Green, Gavin Tjin, Samuel C. Lee, Alistair M. Chalk, Lenny Straszkowski, Diannita Kwang, Emma K. Baker, Julie M. Quach, Takaharu Kimura, Joy Y. Wu, Louise E. Purton
Journal: Blood
Blood (2021) 138 (4): 304–317.
https://doi.org/10.1182/blood.2020005865
Published: 2021
Includes: Supplemental data
Journal Articles

The Pathogenesis of Multiple Myeloma (MM) Is Preceded By Mutated Lymphopoiesis and B Cell Oligoclonality That Persist in Patients with Negative Minimal Residual Disease (MRD)

Sara Rodríguez, PhD, Noemi Puig, MD PhD, Katerina Gemenetzi, Ibai Goicoechea, PhD, Cirino Botta, MD, Andreas Agathangelidis, PhD, Rafael Valdés-Mas, Juan José Garcés, María Teresa Cedena, José J Pérez, Leire Burgos, Maria Jose Calasanz, PhD BSc, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Irene Aires, Idoia Rodriguez, Sarvide Sarai, Felipe Prosper, MD PhD, Jose Angel Martinez-Climent, MD PhD, Alberto Orfao, MD PhD, Ramón García-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Juan-José Lahuerta, MD PhD, Laura Rosinol Dachs, Joan Bladé, MD, Maria-Victoria Mateos, Anastasia Hadzidimitriou, PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 509.
https://doi.org/10.1182/blood-2019-128049
Published: 2019
Journal Articles

Thymus Regeneration Is Dependent on Distinct Mesenchymal Stromal Cell Populations

Karin Gustafsson, PhD, Nikolas Barkas, PhD, Ninib Baryawno, PhD, Elizabeth W Scadden, Nicolas Severe, PhD, Joel A Spencer, PhD, Hayalneh Gessessew, Kameron Kooshesh, Jimin Guo, PhD, Charles Lin, PhD, Peter Kharchenko, PhD, David T. Scadden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 586.
https://doi.org/10.1182/blood-2019-126708
Published: 2019
Journal Articles

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Sara Piccinelli, Antonella Mancusi, PhD, Eni Hoxha, Loredana Ruggeri, MD, Franca Falzetti, MD, Alessandra Carotti, MD, Adelmo Terenzi, MD, Samanta Bonato, MD, Matteo Paradiso, MD, Tiziana Zei, Roberta Iacucci Ostini, Barbara Bigerna, Brunangelo Falini, MD PhD, Mauro Di Ianni, MD PhD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1917.
https://doi.org/10.1182/blood-2019-125715
Published: 2019
Journal Articles

Waldenström's Macroglobulinemia (WM) Is Preceded By Clonal Lymphopoiesis Including MYD88 L265P in Progenitor B Cells

Sara Rodríguez, PhD, Cirino Botta, MD, Jon Celay, PhD, Ibai Goicoechea, PhD, Maria J Garcia-Barchino, PhD, Rafael Valdés-Mas, Yolanda Carrasco, Daniel Alameda, PhD, Juan José Garcés, Marta Larrayoz, PhD, Susana Santos, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Cristina Pérez Ruiz, Sonia Garate, Sarvide Sarai, Amaia Gascue, Christian Reinhardt, MD, Isidro Sanchez-Garcia, PhD, Maria Jose Larrayoz, PhD, Maria Jose Calasanz, PhD BSc, Felipe Prosper, MD PhD, Marina Motta, Antonella Anastasia, Antonio Sacco, RN, Massimo Gentile, Sara Duarte, Helena Vitoria, Catarina Geraldes, MD PhD, Artur Paiva, Aldo M. Roccaro, MD PhD, Jesús San-Miguel, Jose Angel Martinez-Climent, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1527.
https://doi.org/10.1182/blood-2019-126889
Published: 2019
Journal Articles

Telomere Shortening By Terc Knockout in the Eµ-TCL1 Transgenic Murine Model of CLL: Characterization of Disease Development and Survival

Billy Michael Chelliah Jebaraj, PhD, Annika Scheffold, PhD, André Lechel, Sarah-Fee Katz, PhD, Eugen Tausch, Johannes Bloehdorn, MD, Daniela Steinbrecher, PhD, Vanni Torresi, Christof Schneider, MD, Hartmut Döhner, MD, Daniel Mertens, PhD, Lenhard Rudolph, Stephan Stilgenbauer
Journal: Blood
Blood (2019) 134 (Supplement_1): 1732.
https://doi.org/10.1182/blood-2019-126878
Published: 2019
Journal Articles

Trisomy 21 Driven Pro-Inflammatory Signalling in Fetal Bone Marrow May Play a Role in Perturbed B-Lymphopoiesis and Acute Lymphoblastic Leukemia of Down Syndrome

Sorcha Isabella O'Byrne, BSc, Natalina Elliott, PhD, Gemma Buck, BSc, Siobhan Rice, David O'Connor, Jana Oswald, Hannah Fuchs, Ella-Mae Labbett, Nicholas James Fordham, MBBS, BSc, Anindita Roy, MD PhD, Irene Roberts
Journal: Blood
Blood (2019) 134 (Supplement_1): 1206.
https://doi.org/10.1182/blood-2019-130180
Published: 2019
Journal Articles

Hematopoietic Stem Cells Increase Quiescence during Aging

Larisa V. Kovtonyuk, PhD, Peter Ashcroft, PhD, Gianluca Spaltro, MD, Nageswara Rao Tata, Radek C. Skoda, Sebastian Bonhoeffer, Markus G. Manz, Prof.Dr.MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2484.
https://doi.org/10.1182/blood-2019-130668
Published: 2019
Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 748.
https://doi.org/10.1182/blood-2019-127263
Published: 2019
Journal Articles

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Sorcha O’Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Catherine Garnett, Laura Godfrey, Nicholas T. Crump, Gary Wright, Sarah Inglott, Peng Hua, Bethan Psaila, Benjamin Povinelli, David J. H. F. Knapp, Antonio Agraz-Doblas, Clara Bueno, Ignacio Varela, Phillip Bennett, Hashem Koohy, Suzanne M. Watt, Anastasios Karadimitris, Adam J. Mead, Phillip Ancliff, Paresh Vyas, Pablo Menendez, Thomas A. Milne, Irene Roberts, Anindita Roy
Journal: Blood
Blood (2019) 134 (13): 1059–1071.
https://doi.org/10.1182/blood.2019001289
Published: 2019
Includes: Supplemental data
Journal Articles

TGF-β Signaling in Fetal Mesenchymal Progenitor Cells Plays an Essential Role in the Emergence of Bone Marrow Hematopoietic Niches

Grazia Abou Ezzi, PhD, Teerawit Supakorndej, BS, Jingzhu Zhang, BS, Joseph R. Krambs, BS, Hamza Celik, PhD, Daniel C. Link, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3847.
https://doi.org/10.1182/blood-2018-99-117396
Published: 2018
Journal Articles

Leukemia Risk Gene ARID5B is a Crucial Regulator of B-Cell Development

Charnise Goodings-Harris, PhD, Hui Zhang, PhD, Xuijie Zhao, Heng Xu, PhD, Omar I Abdel-Wahab, MD, Shannon McKinney-Freeman, PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 385.
https://doi.org/10.1182/blood-2018-99-113686
Published: 2018
Journal Articles

Normal and Aberrant NKL-Code in B-Cell Development and Lymphoma

Stefan Nagel, PhD, MacLeod A.F. Roderick, PhD, Corinna Meyer, Maren Kaufmann, Hans G. Drexler, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3901.
https://doi.org/10.1182/blood-2018-99-110286
Published: 2018
Journal Articles

Engineering Regenerative Thymic Tissues to Restore Long-Term T Cell Lymphopoiesis

Hui Gai, MD, Rafa Gras~Pena, PhD, Yogendra Verma, MS, Vincent Fateh, BS, Kazuya Ikeda, MD, Beruh Dejene, MS, Dullei Min, Jing Wang, MD, Tomek Swigut, PhD, Ken I. Weinberg, MD, Georg A. Hollander, MD, Sarah Heilshorn, PhD, Maria-Grazia Roncarolo, MD, Vittorio Sebastiano, PhD, Katja G. Weinacht, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5092.
https://doi.org/10.1182/blood-2018-99-117499
Published: 2018
Journal Articles

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Simon Haas, PhD, Chiara Baccin, Jude Al-Sabah, Lars Velten, PhD, Steinmetz Lars, PhD, Andreas Trumpp, Prof, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 876.
https://doi.org/10.1182/blood-2018-99-118479
Published: 2018
Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 566.
https://doi.org/10.1182/blood-2018-99-115913
Published: 2018
Journal Articles

Smoothened signaling in the mouse osteoblastoid lineage is required for efficient B lymphopoiesis

Brief Report
Wenyan Lu, Dominic Dordai, David Huso, Stephen Desiderio
Journal: Blood
Blood (2018) 131 (3): 323–327.
https://doi.org/10.1182/blood-2017-06-793539
Published: 2018
Includes: Supplemental data
Journal Articles

Junctional Adhesion Molecule 2 Intensifies T Lymphopoiesis of Hematopoietic Stem Cells By Facilitating Notch/Delta Signaling

Visnja Radulovic, PhD, Mark Van Der Garde, PhD, Valgardur Sigurdsson, PhD, Alya Zriwil, PhD, Svetlana Soboleva, Ewa Sitnicka Quinn, PhD, Shin Kaneko, MD PhD, Kenichi Miharada, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 635.
https://doi.org/10.1182/blood.V130.Suppl_1.635.635
Published: 2017
Journal Articles

EBF1 As a Novel Regulator of Bone Marrow Mesenchymal Stromal Progenitors

Marta Derecka, PhD, Senthilkumar Ramamoorthy, PhD, Pierre Cauchy, PhD, Josip Herman, Dominic Grun, PhD, Rudolf Grosschedl, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 96.
https://doi.org/10.1182/blood.V130.Suppl_1.96.96
Published: 2017
Journal Articles

Oncogenic Mutations in XPO1 Promote Lymphoid Transformation By Altering Nuclear/Cytoplasmic Localization of NFκB Signaling Intermediates

Justin Taylor, MD, Xiao Jing Zhang, Stella V Paffenholz, Alexander V Penson, PhD, Matthew Chang, Christina Marcelus, Lillian E Bitner, Young Rock Chung, MS, Akihide Yoshimi, MD, Stanley Chun-Wei Lee, PhD, Myriam Boukhali, MS, Rajesh K Soni, PhD, Ronald C Hendrickson, PhD, Barry S Taylor, PhD, Jose A Rodríguez, PhD, Wilhelm Haas, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 879.
https://doi.org/10.1182/blood.V130.Suppl_1.879.879
Published: 2017