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Journal Articles

Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Jenny Klintman, Niamh Appleby, Basile Stamatopoulos, Katie Ridout, Toby A. Eyre, Pauline Robbe, Laura Lopez Pascua, Samantha J. L. Knight, Helene Dreau, Maite Cabes, Niko Popitsch, Mats Ehinger, Jose I. Martín-Subero, Elías Campo, Robert Månsson, Davide Rossi, Jenny C. Taylor, Dimitrios V. Vavoulis, Anna Schuh

Blood (2021) 137 (20): 2800–2816.

https://doi.org/10.1182/blood.2020005650

Published: 2021

Includes: Supplemental data

Journal Articles

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

Srideshikan Sargur Madabushi, PhD, Darren Zuro, Yu-Lin SU, PhD, Paresh Vishwasrao, MSc, Jamison Brooks, B.S, Liliana E Parra, James F Sanchez, PhD, Jeffrey Wong, MD, Marcin Kortylewski, PhD, Susanta Hui, PhD, DABR.

Blood (2019) 134 (Supplement_1): 3929.

https://doi.org/10.1182/blood-2019-127470

Published: 2019

Journal Articles

The Lymphoma Tumor Microenvironment Influences Toxicity after CD19 CAR T Cell Therapy

Michael D. Jain, MD PhD, Rawan Faramand, MD, Verena Staedtke, MD PhD, Renyuan Bai, MBBS, Sae Bom Lee, Hiroshi Kotani, MD PhD, Kayla Reid, Kristen Spitler, Julio Chavez, Bijal Shah, MD, Christina A Bachmeier, PharmD, Marian Dam, ARNP, Brigett Brandjes, PA, Ricardo J Gonzalez, MD, John E Mullinax, MD PhD, Xuefeng Wang, PhD, Mohammad Hussaini, MD, Frederick L. Locke, MD, Marco L. Davila, MD PhD

Blood (2019) 134 (Supplement_1): 4105.

https://doi.org/10.1182/blood-2019-127305

Published: 2019

Journal Articles

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Weiqing Jing, MD PhD, Juan Chen, PhD, Yuanhua Cai, MD, Yingyu Chen, PhD, Jocelyn A. Schroeder, Weiguo Cui, MD PhD, Qizhen Shi, MD PhD

Blood (2019) 134 (Supplement_1): 92.

https://doi.org/10.1182/blood-2019-123777

Published: 2019

Journal Articles

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Ruben A. Gößmann, Lei Wang, MD, Ming Ni, Mingya Yang, MD, Thomas Luft, Ute Hegenbart, MD, Stefan O. Schönland, MD, Patrick Wuchter, MD, Volker Eckstein, William Hermann Krüger, MD PhD, Ronit Yerushalmi, MD, Katia Beider, Arnon Nagler, MD MSc, Carsten Müller-Tidow, MD, Peter Dreger, Michael Schmitt, MD, Anita Schmitt, MD

Blood (2019) 134 (Supplement_1): 3287.

https://doi.org/10.1182/blood-2019-125049

Published: 2019

Journal Articles

Primary Human NK Cell Gene-Editing Reveals a Critical Role for NKG2A in Cytokine-Induced Memory-like NK Cell Responses

Melissa M Berrien-Elliott, PhD, Wong Pamela, B.S., Carly Neal, B.S., Julia A Wagner, PhD, Michelle Becker-Hapak, BS, Tim Schappe, BS, Matthew L. Cooper, PhD, Emily M Mace, PhD, Todd A Fehniger, MD PhD

Blood (2019) 134 (Supplement_1): 3237.

https://doi.org/10.1182/blood-2019-129162

Published: 2019

Journal Articles

Fli-1 Regulates Multiple T-Cell Subsets during Inflammatory Responses and Experimental Graft-Versus-Host Disease

Steven Douglas Schutt, BS, David Bastian, Hee-Jin Choi, PhD, Yongxia Wu, PhD MD, Mohammed Hanief Sofi, PhD MS, Hung Nguyen, PhD, Xian Zhang, PhD, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 3201.

https://doi.org/10.1182/blood-2019-127577

Published: 2019

Journal Articles

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Xiuli Wang, PhD, Miriam Walter, Ryan Urak, Laura Lim, Vibhuti Vyas, MS, Sally Mokhtari, PhD, Don J. Diamond, PhD, Angelo Cardoso, PhD, John Zaia, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD

Blood (2019) 134 (Supplement_1): 3247.

https://doi.org/10.1182/blood-2019-131843

Published: 2019

Journal Articles

Superior Efficacy of CAR-T Cells Using Marrow-Infiltrating Lymphocytes (MILs TM ) As Compared to Peripheral Blood Lymphocytes (PBLs)

Eric R. Lutz, PhD, Srikanta Jana, PhD, Lakshmi Rudraraju, MS, Elizabeth DeOliveira, Jing Zhou, Sean Mackay, Ivan M. Borrello, MD, Kimberly Noonan, PhD MPH

Blood (2019) 134 (Supplement_1): 4437.

https://doi.org/10.1182/blood-2019-130629

Published: 2019

Journal Articles

The Influence of FLT3-ITD Mutation on Baseline Levels of Selected Cytokines and Soluble Adhesion Molecules in Acute Myeloid Leukemia with Mutated NPM-1

Tomas Kupsa, MD PhD, Jan M Horacek, MD PhD, Ladislav Jebavy, MD PhD, Pavel Zak, MD PhD

Blood (2019) 134 (Supplement_1): 5111.

https://doi.org/10.1182/blood-2019-126433

Published: 2019

Journal Articles

Non-Hematopoietic Lymphoid Stromal Cells Prime Alloreactive CD4 + T Cells in Acute Graft-Versus-Host Disease

Muhammad Shaikh, MSc, Maria Ulbrich, MSc, Juan Gamboa Vargas, BSc, Katja J Ottmüller, PhD, Duc Dung Le, PhD, Zeinab Mokthari, PhD, Joern Pezoldt, PhD, Hermann Einsele, MD, Burkhard Ludewig, PhD, Jochen Huehn, PhD, Andreas Beilhack, MD

Blood (2019) 134 (Supplement_1): 4421.

https://doi.org/10.1182/blood-2019-125665

Published: 2019

Journal Articles

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Meixian Huang, Amit Verma, MBBS, Ke Zeng, MD PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD PhD, Hongbing Ma, MD PhD, Zheng Yin, PhD, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 4446.

https://doi.org/10.1182/blood-2019-131948

Published: 2019

Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD

Blood (2019) 134 (Supplement_1): 907.

https://doi.org/10.1182/blood-2019-132233

Published: 2019

Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 777.

https://doi.org/10.1182/blood-2019-130476

Published: 2019

Journal Articles

CD19-Directed Fast CART Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia: From Bench to Bedside

Cheng Zhang, Jiaping He, Li Liu, Jishi Wang, PhD, Sanbin Wang, Ligen Liu, Lei Gao, Li Gao, Yao Liu, Peiyan Kong, Jia Liu, Yu Han, Yongliang Zhang, Zhe Sun, Xun Ye, Yan He, Lianjun Shen, MD PhD, Wei Cao, Xi Zhang

Blood (2019) 134 (Supplement_1): 1340.

https://doi.org/10.1182/blood-2019-128006

Published: 2019

Journal Articles

Efficacy and Safety of Sevuparin, a Novel Non-Anti-Coagulant Heparinoid, in Patients with Acute Painful Vaso-Occlusive Crisis; A Global, Multicenter Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial (TVOC01)

Bart J. Biemond, MD PhD, Anil Tombak, MD, Yurdanur Kilinc, MD, Murtadha Al-Khabori, MD, Miguel R. Abboud, MD, Mohammed Nafea, MD, Adlette Inati, MD, Yasser Ahmed Mohamed Soliman Wali, MD, Jens Kristensen, MD PhD, Ellen Donnelly, PhD, John Ohd, MD PhD

Blood (2019) 134 (Supplement_1): 614.

https://doi.org/10.1182/blood-2019-124653

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Identifies a Pseudo-Immune Differentiation Axis As the Main Source of Functional Heterogeneity in Follicular Lymphoma B-Cells

Noudjoud Attaf, Inaki Cervera-Marzal, Laurine Gil, Chuang Dong, Jean-Marc Navarro, PhD, Lionel Spinelli, PhD, Bertrand Nadel, PhD, Pierre Milpied, PhD

Blood (2019) 134 (Supplement_1): 548.

https://doi.org/10.1182/blood-2019-125718

Published: 2019

Journal Articles

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Athanasios Papadas, MD, Evan Flietner, BS, Zachary Morrow, BS, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, BS, Chelsea L. Hope, PhD, Adhithi Rajagopalan, BS, Zhi Wen, PhD, Philip Emmerich, Dustin Deming, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Natalie Scott Callander, MD, Alexander Rakhmilevich, Mario Otto, MD PhD, Christian M. Capitini, MD, Jing Zhang, PhD, Fotis Asimakopoulos, PhDMBBChir,

Blood (2019) 134 (Supplement_1): 1210.

https://doi.org/10.1182/blood-2019-131582

Published: 2019

Journal Articles

Tissue-Resident PSGL1 lo CD4 + T Cells Interact with B Cells Via PD-1 and PD-L2 in Gvhd Target Tissues to Augment Autoimmune-like Chronic Gvhd

Xiaohui Kong, PhD, Deye Zeng, MD, Xiwei Wu, PhD, Shijie Yang, PhD, Bixin Wang, Qingxiao Song, MD PhD, Yongping Zhu, Martha Salas, Hanjun Qin, Ubaydah Nasri, Ryotaro Nakamura, MD, Paul J Martin, MD, Aimin Huang, Defu Zeng, MD PhD

Blood (2019) 134 (Supplement_1): 5607.

https://doi.org/10.1182/blood-2019-126315

Published: 2019

Journal Articles

Expansion of T Helper Cell Subsets in Chronic Lymphocytic Leukemia Cell Co-Cultures with Nurselike Cells

Alicia Vaca, PhD, Mariela Sivina, Karen Clise-Dwyer, PhD, Ekaterina Kim, MS, Michael J Keating, MBBS, Alessandra Ferrajoli, MD, William G. Wierda, MD PhD, Dan Li, PhD, Qing Ma, PhD, Jan A. Burger, MD PhD

Blood (2019) 134 (Supplement_1): 1746.

https://doi.org/10.1182/blood-2019-125827

Published: 2019

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Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Targeted Marrow Radiation (TMI) Improves Therapeutic Efficacy of STAT3 Decoy Molecules By Augmenting Its Delivery and Immune Modulation in an AML Mouse Model

The Lymphoma Tumor Microenvironment Influences Toxicity after CD19 CAR T Cell Therapy

Induction of Activated T Follicular Helper Cells Is Critical for Anti-FVIII Inhibitor Development in Hemophilia a Mice

Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Primary Human NK Cell Gene-Editing Reveals a Critical Role for NKG2A in Cytokine-Induced Memory-like NK Cell Responses

Fli-1 Regulates Multiple T-Cell Subsets during Inflammatory Responses and Experimental Graft-Versus-Host Disease

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Superior Efficacy of CAR-T Cells Using Marrow-Infiltrating Lymphocytes (MILs TM ) As Compared to Peripheral Blood Lymphocytes (PBLs)

The Influence of FLT3-ITD Mutation on Baseline Levels of Selected Cytokines and Soluble Adhesion Molecules in Acute Myeloid Leukemia with Mutated NPM-1

Non-Hematopoietic Lymphoid Stromal Cells Prime Alloreactive CD4 + T Cells in Acute Graft-Versus-Host Disease

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

CD19-Directed Fast CART Therapy for Relapsed/Refractory Acute Lymphoblastic Leukemia: From Bench to Bedside

Efficacy and Safety of Sevuparin, a Novel Non-Anti-Coagulant Heparinoid, in Patients with Acute Painful Vaso-Occlusive Crisis; A Global, Multicenter Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial (TVOC01)

Single-Cell RNA Sequencing Identifies a Pseudo-Immune Differentiation Axis As the Main Source of Functional Heterogeneity in Follicular Lymphoma B-Cells

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Tissue-Resident PSGL1 lo CD4 + T Cells Interact with B Cells Via PD-1 and PD-L2 in Gvhd Target Tissues to Augment Autoimmune-like Chronic Gvhd

Expansion of T Helper Cell Subsets in Chronic Lymphocytic Leukemia Cell Co-Cultures with Nurselike Cells

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