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Journal Articles

The AHR: adaptive evolution or one-off?

Michael H. Kroll
Journal: Blood
Blood (2019) 134 (26): 2337–2338.
https://doi.org/10.1182/blood.2019003943
Published: 2019
Journal Articles

Effects of Interferon-γ on Proliferation and Ability of Secretion of Human Amniotic Mesenchymal Stem Cells

Ya Gao, MD, Ying Xu, Weiru Li, Yintian Zhang, Baohong Ping, Qifa Liu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5012.
https://doi.org/10.1182/blood-2019-125500
Published: 2019
Journal Articles

Integrated Multi-Level Omics to Characterize Bortezomib Resistance in Multiple Myeloma

David C. Koomen, BS, Mark B. Meads, PhD, Dario M. Magaletti, Joy D. Guingab, PhD, Paula S. Oliveira, Bin Fang, PhD, Victoria Izumi, MS, Rafael Renatino-Canevarolo, PhD, Praneeth Reddy Sudalagunta, PhD, Maria Silva, Raghunandanreddy Alugubelli, MS, Gabe De Avilla, Alex Tungeskiv, Eric A. Welsh, PhD, Laurel E. Meke, Wei Zhang, PhD, Steven A. Eschrich, PhD, Timothy J. Garrett, PhD, Ariosto Siqueira Silva, PhD, John M. Koomen, PhD, Kenneth H. Shain, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5534.
https://doi.org/10.1182/blood-2019-132001
Published: 2019
Journal Articles

Quantitative Assessment of Indoleamine 2,3-Dioxygenase (IDO) Expression at Diagnosis Predicts Clinical Outcome in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation

Sarah Parisi, Simone Ragaini, Darina Ocadlikova, Mariangela Lecciso, Giovanni Marconi, Stefania Paolini, MD PhD, Cristina Papayannidis, Maria Chiara Abbenante, Chiara Sartor, Giovanni Martinelli, MD, Emanuela Ottaviani, Francesca Bonifazi, Michele Cavo, MD, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 5261.
https://doi.org/10.1182/blood-2018-99-115908
Published: 2018
Journal Articles

Targeting Tryptophan Catabolic Kynurenine Pathway Enhances Anti-Tumor Immunity and Cytotoxicity in Multiple Myeloma

Arghya Ray, PhD, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1930.
https://doi.org/10.1182/blood-2018-99-117827
Published: 2018
Journal Articles

Metabolomics Profiling after Allogeneic Hematopoietic Stem Cell Transplantation Unravels a Specific Signature in Human Acute GVHD

David Michonneau, MD, Eleonora Latis, Laetitia Dubouchet, Regis Peffault De Latour, Marie Robin, MD PhD, Flore Sicre De Fontbrune, MD PhD, Lars Rogge, PhD, Gerard Socie, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 69.
https://doi.org/10.1182/blood-2018-99-110441
Published: 2018
Journal Articles

Newly Identified Metabolites Connect Colon Cancer to Thrombosis

Mostafa Belghasem, MD PhD, Daniel Michael Roth, MSc, BSc, Joshua Aaron Walker, PhD, Sean Richards, Cheryl Spencer, Joseph Yeghishe Tashijan, BSc, Nkriuka Arinze, MD, Chris Andry, MPhil, PhD, Katya Ravid, PhD DSc, Vipul Chitalia, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 78.
https://doi.org/10.1182/blood-2018-99-113680
Published: 2018
Journal Articles

IDO Pathway Analysis for Identifying Novel Biomarkers in Multiple Myeloma

Vladimir Petrovic, PhD, Jamie Wong, Cedric E. Dos Santos, PhD, Richard Smith, Dan Fitzpatrick, Robert Loberg, Ariel Avilion, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5572.
https://doi.org/10.1182/blood-2018-99-111392
Published: 2018
Journal Articles

Immunoregulatory Properties of Apoptotic Human Amniontic Mesenchymal Stromal Cells

Ying Xu, Ya Gao, MD, Yan chun Yang, Dongmao Zhu, Yintian Zhang, Ke Zhao, Yu Zhang, Qifa Liu, MD, Haitao Sun, Baohong Ping
Journal: Blood
Blood (2018) 132 (Supplement 1): 5678.
https://doi.org/10.1182/blood-2018-99-112585
Published: 2018
Journal Articles

Indoximod Combined with Standard Induction Chemotherapy Is Well Tolerated and Induces a High Rate of Complete Remission with MRD-Negativity in Patients with Newly Diagnosed AML: Results from a Phase 1 Trial

Ashkan Emadi, MD PhD, Vu H. Duong, MD, Jeremy Pantin, MD, Mohammad Imran, MD, Rima Koka, MD PhD, Zeba Singh, MBBS, Edward A. Sausville, MD PhD, Jennie Y. Law, MD, Seung Tae Lee, MD PhD, Huidong Shi, PhD, Ravindra Kolhe, MD PhD, Maria R. Baer, MD, Michael R. Loken, PhD, Eugene P. Kennedy, MD, Charles Link, MD, David H. Munn, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 332.
https://doi.org/10.1182/blood-2018-99-117433
Published: 2018
Journal Articles

Effects of a Folic Acid 5 Mg Daily Intervention on Markers of Vitamin B Status and Kynurenine Pathway

Guilherme Wataru Gomes, MSc, Maylla Rodrigues Lucena, MSc, Per Magne Ueland, MD PhD, Oivind Midttun, PhD, Clovis Paniz, PhD, Juliano Felix Bertinato, MSc, Cecilia Zanin Palchetti, PhD, Elvira Maria Guerra-Shinohara, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4739.
https://doi.org/10.1182/blood.V130.Suppl_1.4739.4739
Published: 2017
Journal Articles

Identification of Metabolic Enzymes ENO1 and KMO As Novel Immunotherapeutic Targets in Myeloma

Arghya Ray, PhD, Deepika S DAS, PhD, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1792.
https://doi.org/10.1182/blood.V130.Suppl_1.1792.1792
Published: 2017
Journal Articles

Utilization of Metabolomics to Identify Biomarkers in Hematological Malignancies: Role of IDO and the Tryptophan Pathway

Elizabeth Finger, Jamie Wong, Julia Gray, Dan Rock, Robert Loberg, Dan Fitzpatrick, Richard Smith, Xiaozhen Wang, Cedric E. Dos Santos
Journal: Blood
Blood (2017) 130 (Supplement 1): 5100.
https://doi.org/10.1182/blood.V130.Suppl_1.5100.5100
Published: 2017
Journal Articles

Global and Targeted Metabolic Profiling Identifies Metabolic Markers for FLT3-ITD in Pediatric AML Patients

Bradley Stockard, PharmD, Joy Guingab, PhD, Timothy Garrett, PhD, Stanley Pounds, PhD, Jeffrey E Rubnitz, MD PhD, Jatinder Lamba, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5105.
https://doi.org/10.1182/blood.V130.Suppl_1.5105.5105
Published: 2017
Journal Articles

Gls Inhibitor CB-839 Modulates Cellular Metabolism in AML and Potently Suppresses AML Cell Growth When Combined with 5-Azacitidine

Tianyu Cai, PhD, Philip L Lorenzi, PhD, Dinesh Rakheja, MD, Michael A Pontikos, Alessia Lodi, Lina Han, MD PhD, Qi Zhang, MD PhD, Helen Ma, MS, Mohamed Rahmani, PhD, Tushar Damodar Bhagat, PhD, Thomas D Horvath, PhD, Courtney D. DiNardo, MD MSCE, Steven Grant, MD, Stefano Tiziani, PhD, Amit Verma, MD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4064.
https://doi.org/10.1182/blood.V128.22.4064.4064
Published: 2016
Journal Articles

The Roles of Aryl Hydrocarbon Receptor in T Cells at IDO-Positive Tumor Microenvironment

Soranobu Ninomiya, MD PhD, Nobuhiko Nakamura, MD PhD, Junichi Kitagawa, MD PhD, Takeshi Hara, MD PhD, Masahito Shimizu, MD PhD, Hisashi Tsurumi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3693.
https://doi.org/10.1182/blood.V128.22.3693.3693
Published: 2016
Journal Articles

Indoleamine 2,3-Dioxygenase (IDO1) Levels and Activity Are Increased in Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) and Correlate with Molecular Response to Nilotinib Therapy

Sieghart Sopper, PhD, Satu Mustjoki, MD PhD, Gunther Gastl, Prof., Dr., Zlatko Trajanoski, Prof. Dr., Frank Giles, MD MB, Andreas Hochhaus, MD, Simon Geisler, Dietmar Fuchs, Prof. Dr., Dominik Wolf, MD, Jeroen J.W.M. Janssen, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1912.
https://doi.org/10.1182/blood.V128.22.1912.1912
Published: 2016
Journal Articles

The Value of Combination of Serum L-Kynurenine Level and Expression of Indoleamine 2,3-Dioxygenase mRNA As a Prognostic Factor in Acute Myeloid Leukemia

Hisashi Tsurumi, MD PhD, Takuro Matsumoto, MD, Yuhei Shibata, MD, Nobuhiko Nakamura, MD PhD, Hiroshi Nakamura, MD, Soranobu Ninomiya, MD PhD, Junichi Kitagawa, MD PhD, Yasuhito Nannya, MD PhD, Masahito Shimizu, MD PhD, Takeshi Hara, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4947.
https://doi.org/10.1182/blood.V126.23.4947.4947
Published: 2015
Journal Articles

ATG and Statins Reduce Incidence of Severe Chronic Gvhd By Distinct Mechanisms Involving CXCL9 and Kynurenine Catabolism

Thomas Luft, MD PhD, Katharina Schmidt, MD, Karl-Heinz Kellner, PhD, Aleksandar Radujkovic, MD, Nicola Lehners, MD, Mark-Alexander Schwarzbich, MD, Ute Hegenbart, MD, Anthony D. Ho, MD, Peter Dreger, MD
Journal: Blood
Blood (2015) 126 (23): 856.
https://doi.org/10.1182/blood.V126.23.856.856
Published: 2015
Journal Articles

A Phase II Study to Determine the Safety and Efficacy of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase (IDO) Enzyme INCB024360 in Patients with Myelodysplastic Syndromes

Rami S Komrokji, MD, Sheng Wei, MD, Adam W Mailloux, PhD, Ling Zhang, MD, Eric Padron, MD, Jeffrey E. Lancet, MD, Sara Tinsley, ARNP, Lisa A Nardelli, BS, CCRP, Cynthia Benoit, RN, Javier Pinilla-Ibarz, MD PhD, Pearlie K Epling-Burnette, PhD, Alan F List, MD
Journal: Blood
Blood (2014) 124 (21): 4653.
https://doi.org/10.1182/blood.V124.21.4653.4653
Published: 2014