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Journal Articles

A Novel Protease-Mediated Chimeric Antigen Receptor (CAR): "Double-Arm" CAR-T Cell System Improves Target Specificity of CAR-T Cell Therapy

Satoru Aoyama, MD, Shunichiro Yasuda, MD, Daisuke Watanabe, MD, Hiroki Akiyama, MD, PhD, Yoshihiro Umezawa, MD, PhD, Ayako Nogami, MD PhD BPharm, Osamu Miura, MD, PhD, Norihiko Kawamata, MD, PhD

Blood (2019) 134 (Supplement_1): 1941.

https://doi.org/10.1182/blood-2019-121973

Published: 2019

Journal Articles

A Novel Recurrent Gain-of-Function Mutation of Rltpr Q575E in Adult T Cell Leukemia/Lymphoma

Yuichiro Uchida, Makoto Yoshimitsu, MD PhD, Yuhei Kamada, MD PhD, Naosuke Arima, MD, Kenji Ishitsuka, MD PhD

Blood (2019) 134 (Supplement_1): 1489.

https://doi.org/10.1182/blood-2019-124641

Published: 2019

Journal Articles

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Anna Kaci, PhD, Emilie Adiceam, Melanie Dupont, Marine Garrido, Jeannig Berrou, Hanane Djamai, Andre Baruchel, Mike Burbridge, Claude Gardin, Herve Dombret, MD PhD, Thorsten Braun, MD

Blood (2019) 134 (Supplement_1): 2631.

https://doi.org/10.1182/blood-2019-125641

Published: 2019

Journal Articles

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 2516.

https://doi.org/10.1182/blood-2019-129372

Published: 2019

Journal Articles

CARMA1 Is Required for Notch1-Induced NF-κb Activation in T-Cell Acute Lymphoblastic Leukemia

Rong Wang, Ninghan Zhang, Yuan Feng, Tingting Shao, Huihui Zhang, Ting Pan, Jianlin Qiao, PhD, Kailin Xu, MD, Mingshan Niu, PhD

Blood (2019) 134 (Supplement_1): 1260.

https://doi.org/10.1182/blood-2019-125796

Published: 2019

Journal Articles

A Novel Source of Endogenous DNA Damage That Requires Repair By the Fanconi Anemia Pathway

Moonjung Jung, MD, Sunandini Sridhar, PhD, Audrey Goldfarb, BA, Ryan White, PhD, Danielle Keahi, BA, Raymond Noonan, BA, Tom Wiley, BS, Francis P. Lach, BS, Agata Smogorzewska, MD PhD

Blood (2019) 134 (Supplement_1): 106.

https://doi.org/10.1182/blood-2019-127686

Published: 2019

Journal Articles

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Taylor J Chen, BS, Ye Shen, PhD, Cory Seth Bridges, BS, Chun Shik Park, PhD, Jacob J. Junco, PhD, Karen R. Rabin, MD PhD, H. Daniel Lacorazza, PhD

Blood (2019) 134 (Supplement_1): 3889.

https://doi.org/10.1182/blood-2019-129127

Published: 2019

Journal Articles

The First Functional HLA-a*01:01-Restricted EBV-LMP2-Specific T-Cell Receptors for TCR Gene Therapy of Patients with EBV-Associated Type II/III Malignancies

Wesley Huisman, MSc, Ilse Gille, Lieve E. van der Maarel, Lois Hageman, Rob C.M. de Jong, PhD, Derk Amsen, PhD, Fred Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2019) 134 (Supplement_1): 4448.

https://doi.org/10.1182/blood-2019-123736

Published: 2019

Journal Articles

Targeting Intracellular WT1 in AML Utilizing a T Cell Bispecific Antibody Construct: Augmenting Efficacy through Combination with Lenalidomide

Blood (2019) 134 (Supplement_1): 4450.

https://doi.org/10.1182/blood-2019-130121

Published: 2019

Journal Articles

Lw-218, a New Flavonoid Compound, Exerts Anti-T-Cell Malignancies Effects Via Autophagy-Mediated Apoptosis

Po Hu, Hui Li, Bao-An Chen, Hua Tang, Zheng Ge, MD PhD, Jing Zhang, Hui Hui, Qing-long Guo

Blood (2019) 134 (Supplement_1): 5756.

https://doi.org/10.1182/blood-2019-122409

Published: 2019

Journal Articles

Detection of Low Frequency T-Cell Clones Via a Next Generation Sequencing (NGS) Based Immune-Oncology Research Assay

John Williamson, MS, CLS, Timothy Looney, PhD, Geoffrey Lowman, PhD, Harwinder Sidhu, BS, Luis Solano, BS, Suzanne Salazar, MBA, CLS, Huan Tian, PhD, Rajendra Ramsamooj, MD

Blood (2019) 134 (Supplement_1): 5774.

https://doi.org/10.1182/blood-2019-127459

Published: 2019

Journal Articles

Genome-Wide microRNA Expression Profiling in Molecular Subgroups of Peripheral T-Cell Lymphoma Identified Role of Mir-126 in T-Cell Lymphomagenesis

Waseem Lone, PhD, Alyssa Bouska, PhD, Tyler Herek, BS,MS, Catalina Amador, MD, Mallick Saumyaranajn, MD, Yu Jiayu, Tayla Heavican, Stefano A. Pileri, MD PhD, Timothy McKeithan, MD PhD, Wing C. Chan, MD, Javeed Iqbal, PhD

Blood (2019) 134 (Supplement_1): 2767.

https://doi.org/10.1182/blood-2019-129327

Published: 2019

Journal Articles

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Hiroo Katsuya, MD, Paola Miyazato, PhD, Saiful Islam, Benjy Jek Yang Tan, MD, Yuki Inada, Misaki Matsuo, Takaharu Ueno, Masahito Tokunaga, MD PhD, Hiroyuki Hata, MD PhD, Makoto Yamagishi, PhD, Jun-Ichi Fujisawa, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD, Atae Utsunomiya, MD, Shinya Kimura, MD PhD, Yorifumi Satou, MD PhD

Blood (2019) 134 (Supplement_1): 2779.

https://doi.org/10.1182/blood-2019-124361

Published: 2019

Journal Articles

Eltrombopag: More Than Just a Thrombopoietin Receptor Agonist (TPO-RA) in Immune Thrombocytopenia (ITP)

Anwar A. Sayed, MBBS, MSc, PhD, Amna Malik, PhD, Grace Ayoola, BSc., Elisa Lucchini, MD, Sasfia Candrianita, MD, Michelle H Tan, BSc, Camelia Vladescu, MSc, Deena Paul, Alice C J Hart, MBBS, BSc, MRCP, FRCPath(Haem), Ahmad Khoder, MD PhD MRCP, ASCP, Nesrina Imami, PhD, Nichola Cooper, MD MRCP

Blood (2019) 134 (Supplement_1): 2364.

https://doi.org/10.1182/blood-2019-122848

Published: 2019

Journal Articles

A Multi-Drug Tolerant Phenotype Is Induced By Diverse Microenvironmental Agonists in Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

Kallesh D. Jayappa, DVM, PhD, Konrad J. Cios, BSc (2019), Vicki L. Gordon, BSc, Puja C. Arora, MD, Timothy P. Bender, PhD, Michael E. Williams, MD, Craig A. Portell, MD, Michael J. Weber, PhD

Blood (2018) 132 (Supplement 1): 4120.

https://doi.org/10.1182/blood-2018-99-119521

Published: 2018

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas

Salvia Jain, MD, Alexandria Van Scoyk, Elizabeth A Morgan, MD, Andrew Matthews, MD, Kristen E. Stevenson, MS, Gail Newton, PhD, Anu K Autio, PhD, Marisa O. Peluso, MS, Rachel W O'Connor, BS, Alison M. Paterson, PhD, Pamela M. Holland, PhD, Francis W Luscinskas, PhD, David M Weinstock, MD

Blood (2018) 132 (Supplement 1): 339.

https://doi.org/10.1182/blood-2018-99-112986

Published: 2018

Journal Articles

Growth Arrest-Specific 2 Promotes the Growth of T-Cell Acute Lymphoblastic Leukemia Cells Via Its Regulation of CXCR4

Wenjuan Ma, Yan Wan, Haixia Zhou, MD PhD, Li Zhu, MD PhD, Yun Zhao, PhD

Blood (2018) 132 (Supplement 1): 4081.

https://doi.org/10.1182/blood-2018-99-114354

Published: 2018

Journal Articles

Mechanisms Underlying Augmented Lymphomagenesis by LUBAC; Possible Accumulation of AID-Mediated Somatic Mutations

Tomoyasu Jo, MD, Momoko Nishikori, MD PhD, Yoshiteru Sasaki, MD PhD, Yasunori Kogure, MD PhD, Keisuke Kataoka, MD PhD, Seishi Ogawa, MD PhD, Kazuhiro Iwai, MD PhD, Akifumi Takaori-Kondo, MD PhD

Blood (2018) 132 (Supplement 1): 775.

https://doi.org/10.1182/blood-2018-99-111097

Published: 2018

Journal Articles

The Fully Human Anti-CD47 Antibody SRF231 Has Dual-Mechanism Antitumor Activity Against Chronic Lymphocytic Leukemia (CLL) Cells and Increases the Activity of Both Rituximab and Venetoclax

Rebecca Valentin, MD, Marisa O. Peluso, MS, Timothy Z. Lehmberg, BA, Ammar Adam, DVM, Li Zhang, MA, Caroline M. Armet, BS, Jennifer L. Guerriero, PhD, Benjamin H. Lee, MD PhD, Vito J. Palombella, PhD, Pamela M. Holland, PhD, Alison M. Paterson, PhD, Matthew S. Davids, MD

Blood (2018) 132 (Supplement 1): 4393.

https://doi.org/10.1182/blood-2018-99-110181

Published: 2018

NARROW

A Novel Protease-Mediated Chimeric Antigen Receptor (CAR): "Double-Arm" CAR-T Cell System Improves Target Specificity of CAR-T Cell Therapy

A Novel Recurrent Gain-of-Function Mutation of Rltpr Q575E in Adult T Cell Leukemia/Lymphoma

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Human Acute Leukemia Is Addicted to Branched-Chain Amino Acid Metabolism to Maintain Leukemia Stemness

CARMA1 Is Required for Notch1-Induced NF-κb Activation in T-Cell Acute Lymphoblastic Leukemia

A Novel Source of Endogenous DNA Damage That Requires Repair By the Fanconi Anemia Pathway

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

The First Functional HLA-a*01:01-Restricted EBV-LMP2-Specific T-Cell Receptors for TCR Gene Therapy of Patients with EBV-Associated Type II/III Malignancies

Targeting Intracellular WT1 in AML Utilizing a T Cell Bispecific Antibody Construct: Augmenting Efficacy through Combination with Lenalidomide

Lw-218, a New Flavonoid Compound, Exerts Anti-T-Cell Malignancies Effects Via Autophagy-Mediated Apoptosis

Detection of Low Frequency T-Cell Clones Via a Next Generation Sequencing (NGS) Based Immune-Oncology Research Assay

Genome-Wide microRNA Expression Profiling in Molecular Subgroups of Peripheral T-Cell Lymphoma Identified Role of Mir-126 in T-Cell Lymphomagenesis

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Eltrombopag: More Than Just a Thrombopoietin Receptor Agonist (TPO-RA) in Immune Thrombocytopenia (ITP)

A Multi-Drug Tolerant Phenotype Is Induced By Diverse Microenvironmental Agonists in Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas

Growth Arrest-Specific 2 Promotes the Growth of T-Cell Acute Lymphoblastic Leukemia Cells Via Its Regulation of CXCR4

Mechanisms Underlying Augmented Lymphomagenesis by LUBAC; Possible Accumulation of AID-Mediated Somatic Mutations

The Fully Human Anti-CD47 Antibody SRF231 Has Dual-Mechanism Antitumor Activity Against Chronic Lymphocytic Leukemia (CLL) Cells and Increases the Activity of Both Rituximab and Venetoclax

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American Society of Hematology

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ASH Publications

American Society of Hematology

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