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Journal Articles

TLR8 gain of function: a tall surprise

Bertrand Boisson, Jean-Laurent Casanova

Blood (2021) 137 (18): 2420–2422.

DOI: https://doi.org/10.1182/blood.2020010463

Published: 2021

Journal Articles

Platelet Function in Paroxysmal Nocturnal Haemoglobinuria

Fathima Mohiyaddin Ayyalil, MBBS, FRACP,FRCPA, Samantha J Montague, BSc, PhD, Sarah Hicks, Amandeep Kaur, PhD, Anila Jahangiri, Nalini Pati, MBBS,FRACP,FRCPA, DCH, MD DNB, Philip Crispin, MBBS, FRACP, FRCPA, Yujie Zheng, Xu Tienan, Lucy Coupland, PhDBSc,RN, Woei Ming Lee, James D'Rozario, MBBS, FRACP, FRCPA, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 4884.

DOI: https://doi.org/10.1182/blood-2019-130291

Published: 2019

Journal Articles

Efficacy of Mesenchymal Stem Cells in Bronchiolitis Obliterans Syndrome after Allogeneic HSCT: A Multicenter Prospective Cohort Study

Shan Chen, MD, Ke Zhao, MD, Ren Lin, MD, Shunqing Wang, Zhiping Fan, MD, Fen Huang, MD, Xiaoyong Chen, PhD, Danian Nie, MD, Xin Du, MD, Ziwen Guo, MD, Dongjun Lin, MD, Li Xuan, MD, Na Xu, MD, Jing Sun, MD, Andy Peng Xiang, PhD, Qifa Liu, MD

Blood (2019) 134 (Supplement_1): 871.

DOI: https://doi.org/10.1182/blood-2019-124455

Published: 2019

Journal Articles

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

Brian Giacopelli, BS, Min Wang, Ada C Cleary, Yue-zhong Wu, MSc, Anna Reister Schultz, James S. Blachly, MD, Ann-Kathrin Eisfeld, MD, Kevin R Coombes, Clara D. Bloomfield, MD, Brian J. Druker, Jeffrey W. Tyner, John C. Byrd, MD, Christopher C. Oakes, PhD

Blood (2019) 134 (Supplement_1): 1413.

DOI: https://doi.org/10.1182/blood-2019-126212

Published: 2019

Journal Articles

ILF2 Antisense Oligonucleotide Therapy and a CRISPR/Cas9-Based Screening for DNA Repair Effectors Identify Synthetic Lethal Approaches Enhancing Myeloma Cells Sensitivity to DNA Damage

Natthakan Thongon, PhD, Christopher Jackson, BS, Pamela Lockyer, MS, Jintan Liu, Andrea Santoni, PhD, Ashley Rose, BS, Guillermo Garcia-Manero, MD, Simona Colla, PhD

Blood (2019) 134 (Supplement_1): 685.

DOI: https://doi.org/10.1182/blood-2019-129286

Published: 2019

Journal Articles

A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies

Simon Timothy Abrams, PhD BSc, Ben Morton, MBChB, MD, Yasir Alhamdi, MBChB, PhD, Mohmad Alsabani, Zhenxing Cheng, Steven Lane, PhD, Ingeborg Welters, PhD, Guozheng Wang, MD PhD, Cheng-Hock Toh, MD

Blood (2019) 134 (Supplement_1): 440.

DOI: https://doi.org/10.1182/blood-2019-128493

Published: 2019

Journal Articles

Global Rnaseq/Proteomic-Phoshoproteomic Analysis Unveil Mir-21 As a Central Player in Driving Th17 Mediated Bone Disease in MM

Marco Rossi, MD, Emanuela Altomare, PhD, Cirino Botta, MD, Maria Eugenia Gallo Cantafio, Marco Gaspari, Domenico Taverna, Sarvide Sarai, Daniele Caracciolo, MD, Paola Critelli, MD, Francesco Conforti, Maria Teresa Di Martino, PhD, Bruno Paiva, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD

Blood (2019) 134 (Supplement_1): 505.

DOI: https://doi.org/10.1182/blood-2019-122429

Published: 2019

Journal Articles

Characterization of Immune Cells Producing Regulatory Cytokines That Mediate Engraftment in Sickle Cell Disease Patients after Haploidentical Peripheral Blood Stem Cell Transplantation

Berline Francis, Arunakumar Gangaplara, PhD, Deepali K Bhat, PhD, J. Philip McCoy, PhD, Courtney D. Fitzhugh, MD

Blood (2019) 134 (Supplement_1): 803.

DOI: https://doi.org/10.1182/blood-2019-130711

Published: 2019

Journal Articles

Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis

Yan Zhang, Guoying Zhang, Cui Jian, Congqing Wu, PhD, Nigel Mackman, PhD, Susan Smyth, MD PhD, Yinan Wei, Zhenyu Li, PhD

Blood (2019) 134 (Supplement_1): 3644.

DOI: https://doi.org/10.1182/blood-2019-130439

Published: 2019

Journal Articles

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Martina Barone, PhD, Francesca Ricci, BS, Marco Romano, PhD, Dorian Forte, PhD, Giuseppe Auteri, MD, Francesco Fabbri, PhD, Emanuela Ottaviani, Pierluigi Tazzari, MD, Nicola Vianelli, MD, Giovanni Martinelli, MD, Michele Cavo, Francesca Palandri, PhD MD, Lucia Catani

Blood (2019) 134 (Supplement_1): 1686.

DOI: https://doi.org/10.1182/blood-2019-127322

Published: 2019

Journal Articles

Local Irradiation Induces Systemic Inflammatory Response and Alteration of the Hematopoietic Stem Cell Niche

Yuko Kawano, MD PhD, Daniel K Byun, BS, Benjamin J. Frisch, PhD, Hiroki Kawano, MD PhD, Mark W LaMere, BA, Carl J. Johnston, PhD, Jaqueline P. Williams, PhD, Laura M. Calvi, MD

Blood (2019) 134 (Supplement_1): 1213.

DOI: https://doi.org/10.1182/blood-2019-131809

Published: 2019

Journal Articles

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

James Chavez, BS, Jennifer L Rabe, BS, BA, Kelly Higa, MS, Dirk Loeffler, Ahmed Nouraiz, PhD, Taylor Mills, BA, Beau M Idler, Brett M. Stevens, PhD, Courtney Fleenor, PhD, Claus Nerlov, PhD, Hideaki Nakajima, MD, James Hagman, Timm Schroeder, PhD, Hyun Min Kim, PhD, Craig T Jordan, PhD, James DeGregori, Eric Pietras, PhD

Blood (2019) 134 (Supplement_1): 822.

DOI: https://doi.org/10.1182/blood-2019-129300

Published: 2019

Journal Articles

IL-1β Secreted from Mutant Cells Carrying JAK2- V617Ffavors Early Clonal Expansion and Promotes MPN Disease Initiation and Progression

Shivam Rai, Nils Hansen, Hui Hao-Shen, Stefan Dirnhofer, Nageswara Rao Tata, Radek C. Skoda

Blood (2019) 134 (Supplement_1): 307.

DOI: https://doi.org/10.1182/blood-2019-129800

Published: 2019

Journal Articles

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Amandeep Kaur, PhD, Katherine M Hannan, PhD, Samina Nazir, MSc, Kylee H Maclachlan, FRACP,FRCPA, Gretchen Poortinga, PhD, Si Ming Man, PhD, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Ross D Hannan, PhD, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 2360.

DOI: https://doi.org/10.1182/blood-2019-121713

Published: 2019

Journal Articles

Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

Deokki Eom, BS, Jae Hun Jung, Eun Kyung KIM, PhD, Wolyoung Kim, Qingri Li, Jaehyun Jung, Sohee Im, Yong Dae Shin, Hyaejung Hyun, Joon Seok Park

Blood (2019) 134 (Supplement_1): 4426.

DOI: https://doi.org/10.1182/blood-2019-126839

Published: 2019

Journal Articles

shRNA-Interleukin-6 Modified CD19-Specific Chimeric Antigen Receptor T Cell Significantly Improves the Safety in Acute Lymphoblastic Leukemia

Liqing Kang, Xiaowen Tang, Nan Xu, Minghao Li, Jingwen Tan, Wei Qi, Zhou Yu, Xiaoyan Lou, Shengli Xue, Xin Li, MD, Jian Zhang, MD, Jia Chen, MD, Zhenkun Wang, PhD, Caixia Li, Fu Cheng Cheng, MD PhD, Depei Wu, MD PhD, Lei Yu, MD PhD

Blood (2019) 134 (Supplement_1): 2621.

DOI: https://doi.org/10.1182/blood-2019-132067

Published: 2019

Journal Articles

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

Martin Boettcher, PhD, Konstantinos Panagiotidis, Kristin Mentz, Simon Voelkl, PhD, Heiko Bruns, PhD, Robert Slany, PhD, Andreas Mackensen, MD, Dimitrios Mougiakakos, MD

Blood (2019) 134 (Supplement_1): 2714.

DOI: https://doi.org/10.1182/blood-2019-129689

Published: 2019

Journal Articles

Phase I/II Study of Lenalidomide Combined with DA-EPOCH and Rituximab (DA-EPOCH-R 2 ) in Primary Effusion Lymphoma in Patients with or without HIV

Kathryn Lurain, MDMPH, Ramya Ramaswami, MBBS,MPH, Anaida Widell, RN, Irene Ekwede, RN, Jomy George, PharmD, Maryalice Stetler-Stevenson, MD PhD, Mark Raffeld, MD, Constance M. Yuan, MD PhD, Joseph Ziegelbauer, PhD, Frank Maldarelli, MD PhD, William D. Figg, PharmD, Cody Peer, PhD, Seth M. Steinberg, PhD, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD

Blood (2019) 134 (Supplement_1): 4096.

DOI: https://doi.org/10.1182/blood-2019-122070

Published: 2019

Journal Articles

Clinical Relevance of MYD88 L265P Mutation and Interleukin-10 Level in Cerebrospinal Fluid of Patients with Both Newly Diagnosed and Relapsed Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Blood (2019) 134 (Supplement_1): 4114.

DOI: https://doi.org/10.1182/blood-2019-128298

Published: 2019

Journal Articles

A Phase 1/1b Dose-Escalation Trial Evaluating Cpi-818, an Oral Interleukin-2-Inducible T-Cell Kinase Inhibitor, in Subjects with Relapsed/Refractory T-Cell Lymphoma

Mehrdad Mobasher, MD MPH, Richard A. Miller, MD, James W. Janc, PhD, Long Kwei, PhD, Joseph J. Buggy, PhD, Gabriel Luciano, Anahita Mohammady, PharmD, Won Seog Kim, MD PhD, Youn H. Kim, MD, Michael S. Khodadoust, MD PhD, Steven M. Horwitz, MD, Dejan Radeski, MBBS, FRACP, FRCPA

Blood (2019) 134 (Supplement_1): 4030.

DOI: https://doi.org/10.1182/blood-2019-124958

Published: 2019

2 3 4 5

NARROW

TLR8 gain of function: a tall surprise

Platelet Function in Paroxysmal Nocturnal Haemoglobinuria

Efficacy of Mesenchymal Stem Cells in Bronchiolitis Obliterans Syndrome after Allogeneic HSCT: A Multicenter Prospective Cohort Study

DNA Methylation-Based Classification Highlights the Role of the JAK-STAT Pathway in Acute Myeloid Leukemia

ILF2 Antisense Oligonucleotide Therapy and a CRISPR/Cas9-Based Screening for DNA Repair Effectors Identify Synthetic Lethal Approaches Enhancing Myeloma Cells Sensitivity to DNA Damage

A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies

Global Rnaseq/Proteomic-Phoshoproteomic Analysis Unveil Mir-21 As a Central Player in Driving Th17 Mediated Bone Disease in MM

Characterization of Immune Cells Producing Regulatory Cytokines That Mediate Engraftment in Sickle Cell Disease Patients after Haploidentical Peripheral Blood Stem Cell Transplantation

Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis

The Infection-Driven Production/Secretion of Inflammatory Cytokines By Circulating Monocytes of Myelofibrosis Is Defective and Is Reactivated after In Vivo JAK1/2 Inhibition

Local Irradiation Induces Systemic Inflammatory Response and Alteration of the Hematopoietic Stem Cell Niche

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

IL-1β Secreted from Mutant Cells Carrying JAK2- V617Ffavors Early Clonal Expansion and Promotes MPN Disease Initiation and Progression

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

shRNA-Interleukin-6 Modified CD19-Specific Chimeric Antigen Receptor T Cell Significantly Improves the Safety in Acute Lymphoblastic Leukemia

Microenvironmental Triggers Induce a Chemoresistant, Differentiated Subset of S100A8/A9 high AML Cells Via the Jak/STAT3 Signaling Axis

Phase I/II Study of Lenalidomide Combined with DA-EPOCH and Rituximab (DA-EPOCH-R 2 ) in Primary Effusion Lymphoma in Patients with or without HIV

Clinical Relevance of MYD88 L265P Mutation and Interleukin-10 Level in Cerebrospinal Fluid of Patients with Both Newly Diagnosed and Relapsed Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

A Phase 1/1b Dose-Escalation Trial Evaluating Cpi-818, an Oral Interleukin-2-Inducible T-Cell Kinase Inhibitor, in Subjects with Relapsed/Refractory T-Cell Lymphoma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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