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Journal Articles

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Kira Young, PhD, Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 526.

https://doi.org/10.1182/blood-2019-124534

Published: 2019

Journal Articles

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Kathleen E. McGrath, PhD, Catherman C Seana, MS, Zachary T Hilt, MS, Katherine H Fegan, MS, Paul D. Kingsley, PhD, Leah A Vitt, BS, Massiel Chavez Stolla, PhD, Craig N. Morrell, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2470.

https://doi.org/10.1182/blood-2019-131039

Published: 2019

Journal Articles

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Alireza Paikari, MD, Yankai Zhang, PhD, Alicia Chang, MD, Ankush Goyal, MA, Evadnie Rampersaud, PhD, Jonathan M. Flanagan, PhD, Mitchell J. Weiss, MD, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 811.

https://doi.org/10.1182/blood-2019-131313

Published: 2019

Journal Articles

Functional Characterization of Genes Driving Enhanced Biological Aggressiveness of Myeloma Cells: Identification of Novel and Understudied "Drivers" of Myeloma

Huihui Tang, PhD, Ryosuke Shirasaki, MD PhD, Ricardo De Matos Simoes, PhD, Sara Gandolfi, MD, Olga Dashevsky, PhD, Sondra L. Downey-Kopyscinski, PhD, Brian Glassner, PhD, Michal Sheffer, PhD, Megan Bariteau, BSc, John G Doench, PhD, Constantine S. Mitsiades, MD PhD

Blood (2019) 134 (Supplement_1): 313.

https://doi.org/10.1182/blood-2019-128919

Published: 2019

Journal Articles

GSK1838705a, an IGF-1R/ALK Inhibitor, Overcomes Resistance to Crizotinib in ALK-Positive ALCL

Wenyu Shi, Jian-Yong Li, MD PhD

Blood (2019) 134 (Supplement_1): 4069.

https://doi.org/10.1182/blood-2019-130063

Published: 2019

Journal Articles

Transcriptomic Profile of Bone Marrow-Derived Mesenchymal Stromal Cells of Pediatric Pre-B Acute Lymphoblastic Leukemia Patients and Healthy Donors after Interaction with Leukemic Cells

Tuba Özdemi̇r Sanci, MSc, Hilal Özdağ, PhD, Yasin Köksal, MSc, Seda Tasır Yılmaz, MSc, Husniye Nese Yarali, MD, Namik Yasar Özbek, MD, Habibe Meltem Özgüner, MD

Blood (2019) 134 (Supplement_1): 3957.

https://doi.org/10.1182/blood-2019-128282

Published: 2019

Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2019) 134 (Supplement_1): 3972.

https://doi.org/10.1182/blood-2019-121847

Published: 2019

Journal Articles

Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma

Blood (2019) 134 (Supplement_1): 4407.

https://doi.org/10.1182/blood-2019-130901

Published: 2019

Journal Articles

Seven Cases of JAK2 Mutation Negative Chronic Polycythemia Patients with Elevated IGF-1R

Guanfang Shi, PhD, Rewais Morcus, MD, Maksim Liaukovich, MD, Ching Wong, MD, Vladimir Gotlieb, Jen-Chin Wang, MD

Blood (2019) 134 (Supplement_1): 5389.

https://doi.org/10.1182/blood-2019-123006

Published: 2019

Journal Articles

The Role of Hypoxia on ABL Tyrosine Kinase Inhibitor Resistant Chronic Myeloid Leukemia Cells

Seiichi Okabe, MD PhD, Yuko Tanaka, MD PhD, Mitsuru Moriyama, Akihiko Gotoh, MD PhD

Blood (2019) 134 (Supplement_1): 5369.

https://doi.org/10.1182/blood-2019-129768

Published: 2019

Journal Articles

K lotho Expression Predicts Poor Prognosis in Myelodysplastic Syndrome

Howard Lopes Ribeiro Junior, PhD, João Victor Alves Cordeiro, Student, Roberta Taiane Germano Oliveira, M.Sc., Silvia Maria Meira Magalhães, MD PhD, Ronald F Pinheiro, MD

Blood (2019) 134 (Supplement_1): 5404.

https://doi.org/10.1182/blood-2019-124232

Published: 2019

Journal Articles

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

Juan L Coelho-Silva, BSc, MSc, Diego A Pereira-Martins, MSc, Virginia Campos Silvestrini, BSc, MSc, Eduardo M Rego, MD PhD, Vitor Marcel Faca, PhD, João Agostinho Machado-Neto, PhD, Fabiola Traina, MD PhD

Blood (2019) 134 (Supplement_1): 2689.

https://doi.org/10.1182/blood-2019-132129

Published: 2019

Journal Articles

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

Blood (2019) 134 (6): 534–547.

https://doi.org/10.1182/blood.2018881029

Published: 2019

Includes: Supplemental data

Journal Articles

Targeting BCL-2, BCL-XL, BCL-W and MDM2 in B-Cell Acute Lymphoblastic Leukemia Is Highly Effective Ex Vivo

Helena Hohtari, MD, Shady Awad, MD, Olli Dufva, Swapnil Potdar, MSc, Caroline A Heckman, PhD, Krister Wennerberg, PhD, Satu Mustjoki, MD PhD, Kimmo Porkka, MD PhD

Blood (2018) 132 (Supplement 1): 3975.

https://doi.org/10.1182/blood-2018-99-110610

Published: 2018

Journal Articles

Insulin-like Growth Factor Binding Protein 7 Activates the Retinoid Acid Differentiation Pathway in Acute Myeloid Leukemia Cells

Noortje Van Gils, MSc, Han J.M.P. Verhagen, MSc, Arjo Rutten, Renee X. Menezes, Mei-Ling Tsui, Esmee Dekens, Fedor Denkers, E Vermue, Jeroen J. W. M. Janssen, MD PhD, Gert J. Ossenkoppele, MD PhD, Linda Smit, PhD

Blood (2018) 132 (Supplement 1): 3937.

https://doi.org/10.1182/blood-2018-99-115858

Published: 2018

Journal Articles

The Middle-Aged Bone Marrow Microenvironment Drives Hematopoietic Stem Cell Aging through Altered Production of Insulin-like Growth Factor-1 (IGF1)

Kira Young, PhD, Matthew Loberg, BA, Elizabeth Eudy, BS, Rebecca Bell, BA, Jennifer J. Trowbridge, PhD

Blood (2018) 132 (Supplement 1): 5091.

https://doi.org/10.1182/blood-2018-99-111055

Published: 2018

Journal Articles

Targeting Insulin-like Growth Factor in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant Cells

Yuko Tanaka, Seiichi Okabe, MD PhD, Tetsuzo Tauchi, MD PhD, Yoshikazu Ito, MD PhD, Kazuma Ohyashiki, MD PhD

Blood (2018) 132 (Supplement 1): 5155.

https://doi.org/10.1182/blood-2018-99-114750

Published: 2018

Journal Articles

Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Sharmin Khan, Wen Ling, PhD, Randal Shelton, Joshua Epstein, DSc, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Brian A Walker, PhD, Cody Ashby, PhD, Faith E. Davies, MD, Gareth Morgan, MD, Shmuel Yaccoby, PhD

Blood (2018) 132 (Supplement 1): 1929.

https://doi.org/10.1182/blood-2018-99-116455

Published: 2018

Journal Articles

CRISPR Activation Screen for Drivers of MM Cell Proliferation

Huihui Tang, PhD, Ricardo De Matos Simoes, PhD, Ryosuke Shirasaki, MD PhD, Olga Dashevsky, PhD, Brian Glassner, PhD, Sondra L. Downey-Kopyscinski, PhD, Sara Gandolfi, MD, Michal Sheffer, PhD, Megan Bariteau, BSc, John G Doench, PhD, Constantine S. Mitsiades, MD PhD

Blood (2018) 132 (Supplement 1): 3197.

https://doi.org/10.1182/blood-2018-99-118712

Published: 2018

Journal Articles

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

Malik Bisserier, Narendra Wajapeyee

Blood (2018) 131 (19): 2125–2137.

https://doi.org/10.1182/blood-2017-08-804344

Published: 2018

Includes: Supplemental data

NARROW

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Functional Characterization of Genes Driving Enhanced Biological Aggressiveness of Myeloma Cells: Identification of Novel and Understudied "Drivers" of Myeloma

GSK1838705a, an IGF-1R/ALK Inhibitor, Overcomes Resistance to Crizotinib in ALK-Positive ALCL

Transcriptomic Profile of Bone Marrow-Derived Mesenchymal Stromal Cells of Pediatric Pre-B Acute Lymphoblastic Leukemia Patients and Healthy Donors after Interaction with Leukemic Cells

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma

Seven Cases of JAK2 Mutation Negative Chronic Polycythemia Patients with Elevated IGF-1R

The Role of Hypoxia on ABL Tyrosine Kinase Inhibitor Resistant Chronic Myeloid Leukemia Cells

K lotho Expression Predicts Poor Prognosis in Myelodysplastic Syndrome

IGF1R-IRS1/2 Signaling Pathway Is a Potential Target for FLT3-Mutated Acute Myeloid Leukemia

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

Targeting BCL-2, BCL-XL, BCL-W and MDM2 in B-Cell Acute Lymphoblastic Leukemia Is Highly Effective Ex Vivo

Insulin-like Growth Factor Binding Protein 7 Activates the Retinoid Acid Differentiation Pathway in Acute Myeloid Leukemia Cells

The Middle-Aged Bone Marrow Microenvironment Drives Hematopoietic Stem Cell Aging through Altered Production of Insulin-like Growth Factor-1 (IGF1)

Targeting Insulin-like Growth Factor in Multiple Myeloma: Novel Strategies in the Treatment of Proteasome Inhibitor Resistant Cells

Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors

CRISPR Activation Screen for Drivers of MM Cell Proliferation

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

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American Society of Hematology

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ASH Publications

American Society of Hematology

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