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Journal Articles

Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis

Yan Zhang, Guoying Zhang, Cui Jian, Congqing Wu, PhD, Nigel Mackman, PhD, Susan Smyth, MD PhD, Yinan Wei, Zhenyu Li, PhD

Blood (2019) 134 (Supplement_1): 3644.

https://doi.org/10.1182/blood-2019-130439

Published: 2019

Journal Articles

Integrated Transcriptomic and Proteomic Analyses of Inflammasome in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

María Zurdo, Ana M Hurtado López, Tzu Hua Chen-Liang, Helios Martínez-Banaclocha, Laura Palomo, Félix López Cadenas, MD, Eva Lumbreras, Blanca Xicoy, MD MSc, Lurdes Zamora, PhD, María Díez-Campelo, MD PhD, Francesc Sole, PhD, Pablo Pelegrín, Andres Jerez

Blood (2019) 134 (Supplement_1): 2991.

https://doi.org/10.1182/blood-2019-128094

Published: 2019

Journal Articles

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Daniel Hofbauer, Dimitrios Mougiakakos, MD, Maike Büttner-Herold, Frank Neumann, PhD, Jens Nolting, Savita Bisht, Robert Zeiser, MD, Shaima'A Hamarsheh, MSc,BSc, Stefano Ricagno, PhD, Mario Zaiss, Martin Eberhardt, Martin Boettcher, PhD, Katrin Bitterer, Andreas Mackensen, MD, Heiko Bruns, PhD

Blood (2019) 134 (Supplement_1): 2314.

https://doi.org/10.1182/blood-2019-123958

Published: 2019

Journal Articles

Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes

Grace A Ward, BS, Kathy McGraw, PhD, Amy F McLemore, M.S., Nghi B Lam, M.S., Hsin-An Hou, Benjamin S. Meyer, Alan F. List, MD

Blood (2019) 134 (Supplement_1): 774.

https://doi.org/10.1182/blood-2019-122358

Published: 2019

Journal Articles

Novel Evidence That the Nlrp3 Inflammasome Plays a Role in Bone Marrow As a "Cogwheel" Connecting Purinergic Signaling with Activation of the Complement Cascade to Induce "Sterile Inflammation", Which Is Required for Optimal Mobilization of Hematopoietic Stem/Progenitor Cells

Mateusz Adamiak, PhD, Anna Lenkiewicz, PhD, Kamila Bujko, MS, Arjun Thapa, PhD, Magdalena Kucia, PhD DSci, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc

Blood (2019) 134 (Supplement_1): 4468.

https://doi.org/10.1182/blood-2019-125838

Published: 2019

Journal Articles

Human and Pathogen Derived Ndpks Act As Novel Damps and PAMPs to Drive Leukemia Cell Survival and Progression through Signaling Via the TLR4-Mediated Alternative NLRP3 Inflammasome Pathway

Sandro Trova, PhD, Matthew Fenton, MBChB, Bhavini Chauhan, BSc, Avani Puri, Santosh Lomada, BSc, PhD, Alexandra Adams, Thomas Wieland, BSc, PhD, Mark T Drayson, MB ChB, PhD FRCPath, Farhat Latif Khanim, PhD, Chistopher M Bunce, BSc, Fei Lin, MBChB

Blood (2019) 134 (Supplement_1): 2684.

https://doi.org/10.1182/blood-2019-131236

Published: 2019

Journal Articles

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Aleksandra S. Dain, MD, Michelle L. Hermiston, MD PhD, Kristin A. Shimano, MD, Sandhya Kharbanda, MD, Alexis Melton, MD PhD, Jasmeen Dara, MD, James N Huang, MD, Christopher C. Dvorak, MD

Blood (2019) 134 (Supplement_1): 3343.

https://doi.org/10.1182/blood-2019-127397

Published: 2019

Journal Articles

Nlrp3 Inflammasome Activation in Bone Marrow-Residing Innate Immunity Cells Governs Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells in Peripheral Blood

Mateusz Adamiak, PhD, Andrzej Ciechanowicz, PhD, Monika Cymer, MS, Marta Skoda, PhD, Mariusz Z Ratajczak, MD PhD DSc

Blood (2019) 134 (Supplement_1): 1033.

https://doi.org/10.1182/blood-2019-125853

Published: 2019

Journal Articles

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Marina Jerebtsova, PhD, Xiaomei Niu, MD, Sharmin Diaz, NP, Namita Kumari, PhD, Sergei Nekhai, PhD

Blood (2019) 134 (Supplement_1): 979.

https://doi.org/10.1182/blood-2019-130741

Published: 2019

Journal Articles

We didn’t start the fire, MDSC inflammasome signaling in GVHD

Nataliya Prokopenko Buxbaum

Blood (2019) 134 (19): 1570–1572.

https://doi.org/10.1182/blood.2019003247

Published: 2019

Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Blood (2019) 134 (19): 1670–1682.

https://doi.org/10.1182/blood.2019001950

Published: 2019

Journal Articles

The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes

David A. Sallman, Alan List

Blood (2019) 133 (10): 1039–1048.

https://doi.org/10.1182/blood-2018-10-844654

Published: 2019

Journal Articles

Oncogenic KRAS G12D in the Hematopoietic System Causes NLRP3 Inflammasome Activation Leading to Myeloproliferative Syndrome

Shaima'A Hamarsheh, MSc, BSc, Miriam Erlacher, MD PhD, Lena Osswald, Oliver Gorka, PhD, Justus Duyster, Prof., Olaf Groß, PhD, Claudia Lengerke, MD, Melanie Börries, PhD, Tilman Brummer, PhD, Robert Zeiser, MD

Blood (2018) 132 (Supplement 1): 2618.

https://doi.org/10.1182/blood-2018-99-114161

Published: 2018

Journal Articles

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Jenna M Frame, PhD, Timothy Long, Caroline Schuster-Kubaczka, PhD, Virginie Esain, PhD, Sung Eun Lim, PhD, George Q. Daley, MD PhD, Trista North, PhD

Blood (2018) 132 (Supplement 1): 330.

https://doi.org/10.1182/blood-2018-99-117076

Published: 2018

Journal Articles

Comparative Inflammasome Analysis of Bone Marrow Stroma in Aging and Myelofibrosis

Larissa Balaian, PhD, Leslie A Crews, PhD, Cayla Mayson, BS, Frida Holm, PhD, Raymond H Diep, Heather Leu, BS, Anna Kulidjian, MD, Edward D. Ball, MD, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 4331.

https://doi.org/10.1182/blood-2018-99-118993

Published: 2018

Journal Articles

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

Leslie A Crews, PhD, Phoebe Mondala, BS, Elisa Lazzari, PhD, Gabriel Pineda, PhD, Christina Wu, PhD, Caitlin L. Costello, MD, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 1324.

https://doi.org/10.1182/blood-2018-99-120326

Published: 2018

Journal Articles

Genomic-DNA Exposed By Somatic Gene Mutations Engages the cGAS/STING Axis to License the NLRP3 Inflammasome in Myelodysplastic Syndromes

Amy F McLemore, M.S., Kathy L McGraw, PhD, Hsin-An Hou, MD PhD, Grace A Ward, BS, Alexis H Onimus, BS, Nicole D. Vincelette, PhD, Matthew A. Rodrigues, PhD, Neelkamal Chaudhary, PhD, Ling Zhang, MD, Benjamin S. Meyer, Erika A Eksioglu, PhD MS, Sheng Wei, MD, Alan F. List, MD

Blood (2018) 132 (Supplement 1): 3075.

https://doi.org/10.1182/blood-2018-99-116929

Published: 2018

Journal Articles

Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

Sumra Nazir, Ihsan Gadi, Moh’d Mohanad Al-Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C. Braun-Dullaeus, Charles T. Esmon, Tobias B. Huber, Eric Camerer, Chris Dockendorff, John H. Griffin, Berend Isermann, Khurrum Shahzad

Blood (2017) 130 (24): 2664–2677.

https://doi.org/10.1182/blood-2017-05-782102

Published: 2017

Includes: Supplemental data

Journal Articles

On PAR with aPC to target inflammasomes

Steven R. Lentz

Blood (2017) 130 (24): 2579–2581.

https://doi.org/10.1182/blood-2017-09-806307

Published: 2017

Journal Articles

Association of Inflammatory and Hemostatic Biomarkers with Inflammasomes in Septic Patients at Risk of Developing Coagulopathy

Debra Hoppensteadt, PhD, Richard Green, Grace Wegryzn, Susan Walborn, Michael Mosier, Jawed Fareed, PhD

Blood (2017) 130 (Supplement 1): 4902.

https://doi.org/10.1182/blood.V130.Suppl_1.4902.4902

Published: 2017

NARROW

Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis

Integrated Transcriptomic and Proteomic Analyses of Inflammasome in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes

Novel Evidence That the Nlrp3 Inflammasome Plays a Role in Bone Marrow As a "Cogwheel" Connecting Purinergic Signaling with Activation of the Complement Cascade to Induce "Sterile Inflammation", Which Is Required for Optimal Mobilization of Hematopoietic Stem/Progenitor Cells

Human and Pathogen Derived Ndpks Act As Novel Damps and PAMPs to Drive Leukemia Cell Survival and Progression through Signaling Via the TLR4-Mediated Alternative NLRP3 Inflammasome Pathway

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Nlrp3 Inflammasome Activation in Bone Marrow-Residing Innate Immunity Cells Governs Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells in Peripheral Blood

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

We didn’t start the fire, MDSC inflammasome signaling in GVHD

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes

Oncogenic KRAS G12D in the Hematopoietic System Causes NLRP3 Inflammasome Activation Leading to Myeloproliferative Syndrome

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Comparative Inflammasome Analysis of Bone Marrow Stroma in Aging and Myelofibrosis

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

Genomic-DNA Exposed By Somatic Gene Mutations Engages the cGAS/STING Axis to License the NLRP3 Inflammasome in Myelodysplastic Syndromes

Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

On PAR with aPC to target inflammasomes

Association of Inflammatory and Hemostatic Biomarkers with Inflammasomes in Septic Patients at Risk of Developing Coagulopathy

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American Society of Hematology

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ASH Publications

American Society of Hematology

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