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Journal Articles

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Devi Gunasekera, MBBS, Pooja Vir, PhD, Ahmad Faisal Karim, PhD, Margaret V. Ragni, MD MPH, Elizabeth P. Merricks, PhD, Timothy C. Nichols, MD, Kathleen P. Pratt, PhD

Blood (2019) 134 (Supplement_1): 630.

DOI: https://doi.org/10.1182/blood-2019-124880

Published: 2019

Journal Articles

Low-Dose Immune Tolerance Induction for Hemophilia a Children with Poor-Risk High-Titer Inhibitors

Zekun Li, MBBS, Zhenping Chen, PhDMD, Xiaoling Cheng, Xinyi Wu, Li Gang, Zhen Yingzi, Cai Siyu, Man-Chiu Poon, Runhui Wu, MD PhD

Blood (2019) 134 (Supplement_1): 1122.

DOI: https://doi.org/10.1182/blood-2019-132021

Published: 2019

Journal Articles

Immune Tolerance Induction (ITI) with a Plasma-Derived Factor VIII for Patients with Hemophilia a and Inhibitors: A Retrospective Study

Miguel A. Escobar, MD, Linda Shaffer, Mark Holguin, MD, Timothy McCavit, MD, Sandeep K. Rajan, MD, Novinyo Amega, MD

Blood (2019) 134 (Supplement_1): 4923.

DOI: https://doi.org/10.1182/blood-2019-122949

Published: 2019

Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 5193.

DOI: https://doi.org/10.1182/blood-2019-128348

Published: 2019

Journal Articles

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

Bohan Li, Xinran Chu, Lijun Meng, PhD, Peifang Xiao, MD, Jie Li, MD, Jun Lu, MD, Yi Zhang, MD PhD, Shaoyan Hu, MD PhD

Blood (2019) 134 (Supplement_1): 3288.

DOI: https://doi.org/10.1182/blood-2019-128191

Published: 2019

Journal Articles

Immune Tolerance Induction (ITI) in Paediatric and Adult Patients with Haemophilia a (HA) and High-Titre (HT) Factor VIII (FVIII) Inhibitor - Real Life Data

Magdalena Katarzyna Letowska, Krystyna Zawilska, MD PhD, Anna Klukowska, MD PhD, Krzysztof Chojnowski, MD PhD, Joanna Zdziarska, MD PhD, Ewa Stefanska-Windyga, MD PhD, Jerzy Windyga

Blood (2019) 134 (Supplement_1): 4942.

DOI: https://doi.org/10.1182/blood-2019-122422

Published: 2019

Journal Articles

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Sandra Pinho, PhD, Qiaozhi Wei, PhD, Maria Maryanovich, PhD, Halley Pierce, PhD, Fumio Nakahara, MD PhD, Jianing Xu, PhD, Daniel K. Borger, MS, Dachuan Zhang, PhD, Amit Verma, MBBS, Paul S. Frenette, MD

Blood (2019) 134 (Supplement_1): 524.

DOI: https://doi.org/10.1182/blood-2019-123431

Published: 2019

Journal Articles

Human Leukocyte Antigen-G Restores Immune Tolerance in Immune Thrombocytopenia

Qi Feng, Ji Ma, Xin Li, Ming Hou, Jun Peng, MD PhD

Blood (2018) 132 (Supplement 1): 3751.

DOI: https://doi.org/10.1182/blood-2018-99-115713

Published: 2018

Journal Articles

Successful of Immune Tolerance Induction (R-ITI) with Simoctocog Alfa (rhFVIII) in Hemophilia a Patients and High-Titer Inhibitors

Ezio Zanon, Samantha Pasca, Renato Marino, Angelo Claudio Molinari, MD

Blood (2018) 132 (Supplement 1): 5036.

DOI: https://doi.org/10.1182/blood-2018-99-114615

Published: 2018

Journal Articles

Immune Tolerance Induction with Simoctocog Alfa (Nuwiq ® ) in Six Patients with Severe Haemophilia a and FVIII Inhibitors

Neha Bhatnagar, ND, Kate Khair, Ri Liesner, Alice Wilkinson, Larisa Belyanskaya, PhD

Blood (2018) 132 (Supplement 1): 5037.

DOI: https://doi.org/10.1182/blood-2018-99-118041

Published: 2018

Journal Articles

A Novel Approach to Immune Tolerance Induction in Hemophilia Α with Factor VIII Inhibitor

Courtney D. Thornburg, MD, Jonathan M. Ducore, MD

Blood (2018) 132 (Supplement 1): 5042.

DOI: https://doi.org/10.1182/blood-2018-99-119800

Published: 2018

Journal Articles

The Atlanta Protocol: Immune Tolerance Induction in Pediatric Patients with Hemophilia a and Inhibitors on Emicizumab

Glaivy M. Batsuli, MD, Karen L. Zimowski, MD, Kelly Tickle, MSN, APN, PPCNP-BC, Shannon L. Meeks, MD, Robert F. Sidonio, Jr., MD

Blood (2018) 132 (Supplement 1): 634.

DOI: https://doi.org/10.1182/blood-2018-99-114249

Published: 2018

Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Blood (2018) 132 (Supplement 1): 4344.

DOI: https://doi.org/10.1182/blood-2018-99-113881

Published: 2018

Journal Articles

PD-1-Mediated T Cell Exhaustion Is Prevalent Among Patients with MPN-Associated Myelofibrosis Independent of JAK1/2 Inhibition

Ivo Veletic, MD, Taghi Manshouri, PhD, Graciela M. Nogueras González, MPH, Sanja Prijic, PhD, Joseph E. Bove, IV, Ying Zhang, MD MS, Srdan Verstovsek, MD PhD, Zeev E. Estrov, MD

Blood (2018) 132 (Supplement 1): 5487.

DOI: https://doi.org/10.1182/blood-2018-99-119428

Published: 2018

Journal Articles

Immune Tolerance Induction for FIX Inhibitors Using Combined B and T Cell Immune Modulation Therapy in Severe Hemophilia B

Yasmina L. Abajas, MD, Paul Edward Monahan, MD, Brenda Nielsen, RN, Pia Petrini, MD, Susanna Ranta, MD PhD, Geoffrey A. Allen, MD, Silvia Horneff, MD, Annika Martensson, MD PhD, Johannes Oldenburg, MD PhD, Rolf Ljung, MD PhD Professor

Blood (2018) 132 (Supplement 1): 1193.

DOI: https://doi.org/10.1182/blood-2018-99-120141

Published: 2018

Journal Articles

Intravenous Administration of Recombinant Factor VIII Induces Immune Tolerance to Subcutaneous Turoctocog Alfa Pegol (SC N8-GP) in Humanized Hemophilia A Mice

Stine Louise Reedtz-Runge, Karin Weldingh, Heidi Schiøler Schultz, Anders Holm Millner, Frederik Rode, Bo Wiinberg, Mads Kjelgaard-Hansen

Blood (2018) 132 (Supplement 1): 1194.

DOI: https://doi.org/10.1182/blood-2018-99-111798

Published: 2018

Journal Articles

The Un-BLyS-Ful State: Blocking Factor VIII Inhibitor Development with BLyS Depletion

Bhavya S Doshi, MD, Robert J. Davidson, BS, Valder R Arruda, MD PhD

Blood (2018) 132 (Supplement 1): 138.

DOI: https://doi.org/10.1182/blood-2018-99-114795

Published: 2018

Journal Articles

Induction of Donor-Specific Immune Tolerance with Clinical MIC Cell Infusion — a Phase I Study (TOL-1)

Christian Morath, MD, Anita Schmitt, MD, Christian Kleist, PhD, Volker Daniel, MD, Gerhard Opelz, MD, Caner Süsal, MD, Florian Kälble, MD, Claudia Sommerer, MD, Lei Wang, MD, Angela Hückelhoven, PhD, Arianeb Mehrabi, MD, Uta Merle, MD, Luiza Pego da Silva, Carsten Müller-Tidow, MD, Martin Zeier, MD, Matthias Schaier, MD, Michael Schmitt, MD PhD, Peter Terness, MD

Blood (2018) 132 (Supplement 1): 4539.

DOI: https://doi.org/10.1182/blood-2018-99-113386

Published: 2018

Journal Articles

Economic Impact of Immune Tolerance Induction (ITI) with Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Compared to Conventional Recombinant Factor VIII (rFVIII)

Nanxin Li, Koo Wilson, Marc Botteman, MS, MA, Daniel Nicoloso, Sangeeta Krishnan, PharmD, Jun Su, MD

Blood (2018) 132 (Supplement 1): 3520.

DOI: https://doi.org/10.1182/blood-2018-99-114993

Published: 2018

Journal Articles

Treatment of Haemophilia a (HA) Patients with Inhibitors: Immune Tolerance Induction with a Single Factor VIII/Von Willebrand Factor Concentrate in an Observational Immune Tolerance Induction Study (ObsITI)

C. Escuriola Ettingshausen, Erik Berntorp, MD PhD, Yesim Dargaud, MD PhD, Zeynep Gutowski, PhD, Claude Negrier, Anna Pavlova, MD PhD, Johannes Oldenburg

Blood (2018) 132 (Supplement 1): 2482.

DOI: https://doi.org/10.1182/blood-2018-99-114408

Published: 2018

NARROW

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Low-Dose Immune Tolerance Induction for Hemophilia a Children with Poor-Risk High-Titer Inhibitors

Immune Tolerance Induction (ITI) with a Plasma-Derived Factor VIII for Patients with Hemophilia a and Inhibitors: A Retrospective Study

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Low Levels of Plasmacytoid Dendritic Cells at the Time of Engraftment Are a Valuable Severe aGVHD Indicator in Children Undergoing Allogeneic Stem Cell Transplantation

Immune Tolerance Induction (ITI) in Paediatric and Adult Patients with Haemophilia a (HA) and High-Titre (HT) Factor VIII (FVIII) Inhibitor - Real Life Data

VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells

Human Leukocyte Antigen-G Restores Immune Tolerance in Immune Thrombocytopenia

Successful of Immune Tolerance Induction (R-ITI) with Simoctocog Alfa (rhFVIII) in Hemophilia a Patients and High-Titer Inhibitors

Immune Tolerance Induction with Simoctocog Alfa (Nuwiq ® ) in Six Patients with Severe Haemophilia a and FVIII Inhibitors

A Novel Approach to Immune Tolerance Induction in Hemophilia Α with Factor VIII Inhibitor

The Atlanta Protocol: Immune Tolerance Induction in Pediatric Patients with Hemophilia a and Inhibitors on Emicizumab

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

PD-1-Mediated T Cell Exhaustion Is Prevalent Among Patients with MPN-Associated Myelofibrosis Independent of JAK1/2 Inhibition

Immune Tolerance Induction for FIX Inhibitors Using Combined B and T Cell Immune Modulation Therapy in Severe Hemophilia B

Intravenous Administration of Recombinant Factor VIII Induces Immune Tolerance to Subcutaneous Turoctocog Alfa Pegol (SC N8-GP) in Humanized Hemophilia A Mice

The Un-BLyS-Ful State: Blocking Factor VIII Inhibitor Development with BLyS Depletion

Induction of Donor-Specific Immune Tolerance with Clinical MIC Cell Infusion — a Phase I Study (TOL-1)

Economic Impact of Immune Tolerance Induction (ITI) with Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) Compared to Conventional Recombinant Factor VIII (rFVIII)

Treatment of Haemophilia a (HA) Patients with Inhibitors: Immune Tolerance Induction with a Single Factor VIII/Von Willebrand Factor Concentrate in an Observational Immune Tolerance Induction Study (ObsITI)

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American Society of Hematology

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American Society of Hematology

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