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Journal Articles

Profiling the Cell Surface Landscape of Proteasome Inhibitor-Treated and -Resistant Multiple Myeloma to Guide Immunotherapy Targeting, Diagnosis, and Biology

Ian Ferguson, BA, Yu-Hsiu T. Lin, BA, Sami Tuomivaara, PhD, Jeffrey L. Wolf, MD, Thomas G. Martin, III, MD, Sandy W. Wong, MD, Nina D. Shah, MD, Christoph Driessen, MD, Brian G. Van Ness, PhD, Arun P. Wiita, MD PhD

Blood (2019) 134 (Supplement_1): 1803.

https://doi.org/10.1182/blood-2019-131681

Published: 2019

Journal Articles

20(S)-Protopanaxatriol Promotes Fatty Acid-Induced ER Stress and Apoptosis in Multiple Myeloma By Down-Regulating SCD1 Expression

Qiuguo Wang, Siqi Yan, Xiaoran Zhou, Huiling Mei, Yu Xiang, Bin Fang, Leilei Zhang, Yu Hu, MD PhD, Qiuguo Wang, PhD

Blood (2018) 132 (Supplement 1): 3219.

https://doi.org/10.1182/blood-2018-99-118181

Published: 2018

Journal Articles

Vactosertib, a TGF-ß Receptor I Kinase/ALK5 Inhibitor, Diminishes Tumor Progression and Bone Disease in a Mouse Model of Multiple Myeloma and Overcomes Resistance to Proteasome Inhibitors

Byung-Gyu Kim, PhD DVM, Sung Hee Choi, PhD, George Luo, Olga Sergeeva, PhD, Zhenghong Lee, PhD, James Driscoll, MD PhD, Marcos de Lima, MD, Rose Beck, MD PhD, Seong-Jin Kim, PhD, John Letterio, MD, Ehsan Malek, MD

Blood (2018) 132 (Supplement 1): 1918.

https://doi.org/10.1182/blood-2018-99-117852

Published: 2018

Journal Articles

HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo

Na Yang, Wei Deng, Qiaoling Sun, Junqing Liang, Linfang Wang, Shiming Fan, Renxiang Tang, Ying Yu, Junen Sun, Feng Zhou, Guangxiu Dai, Weiguo Qing, Weiguo Su, Yongxin Ren

Blood (2016) 128 (22): 3970.

https://doi.org/10.1182/blood.V128.22.3970.3970

Published: 2016

Journal Articles

Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of E x V ivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells

Xiao Ma, Xiaoyi Li, Danyue Peng, Huifang Wang, Lei Li, Hao Zhou, Daohong Zhou, Yi Luo, Lingbo Liu

Blood (2016) 128 (22): 2173.

https://doi.org/10.1182/blood.V128.22.2173.2173

Published: 2016

Journal Articles

SL-801, a Novel, Reversible Inhibitor of Exportin-1 (XPO1) / Chromosome Region Maintenance-1 (CRM1) with Broad and Potent Anti-Cancer Activity

Janice Chen, PhD, Christopher L. Brooks, PhD, Peter McDonald, Jonathan D. Schwartz, MD, Rebecca S. Schneider, Keiichi Sakakibara, PhD, Naoya Saito, PhD, Takuji Sato, MSc, Takumi Kawabe, MD PhD, Eric K. Rowinsky, MD

Blood (2015) 126 (23): 4433.

https://doi.org/10.1182/blood.V126.23.4433.4433

Published: 2015

Journal Articles

Leukemia Cell Xenograft in Ovo Enables Real-Time Testing of Response to Therapy

Varda Deutsch, PhD, Sigi Kay, PhD, Hila Jan, MSc, Ben Zion Katz, PhD, Michal Cipok, PhD

Blood (2015) 126 (23): 3781.

https://doi.org/10.1182/blood.V126.23.3781.3781

Published: 2015

Journal Articles

Evaluation of Anti-Neoplastic Effects of a New Hemostatic Agent Ankaferd Blood Stopper on Myeloma Cell Line and Plasmocytoma Development in Balb/c Mice: Results of the First in Vitro and in Vivo Study

Ferit Avcu, MD, Mustafa Guner, Int Dr, Muammer Misirci, Int Dr, Pinar Elci, DDS, Mukerrem Safali, MD, Hakan Goker, MD, Ibrahim Celalettin Haznedaroglu, MD

Blood (2014) 124 (21): 5728.

https://doi.org/10.1182/blood.V124.21.5728.5728

Published: 2014

Journal Articles

BCL6 Dose Not Negatively Regulate DNA Damage Response Genes in Multiple Myeloma Cells

Kenichi Tahara, MD, Makiko Takizawa, MD, PhD, Hiroshi Handa, MD, PhD, Yuta Masuda, Ayaka Kaneko, Itsumi Suda, Kei Kimura, Yuko Kuroda, Isoda Atsushi, MD, PhD, Morio Matsumoto, Hiromi Koiso, MD, PhD, Ishizaki Takuma, MD, PhD, Takeki Mitsui, MD, PhD, Akihiko Yokohama, MD, PhD, Takayuki Saitoh, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hirokazu Murakami, MD, PhD

Blood (2014) 124 (21): 2035.

https://doi.org/10.1182/blood.V124.21.2035.2035

Published: 2014

Journal Articles

Combined Carfilzomib and Selective PI3Kδ Inhibition (TGR1202) Results In Enhanced Myeloma Cell Apoptosis

Claire Torre, Yanyan Gu, MD, PhD, Lawrence H. Boise, PhD, Sagar Lonial, M.D.

Blood (2013) 122 (21): 3224.

https://doi.org/10.1182/blood.V122.21.3224.3224

Published: 2013

Journal Articles

New Xenograft Method For Studying Leukemia and Drug Response In Turkey Embryos

Varda R Deutsch, PhD, Sigi Kay, PhD, Yona Farnoushi, MSc, Erez Matalon, MSc, Tal Ohayon, MSc, Shoshana Baron, Hila Jan, MSc, Elizabeth Naparstek, MD, Michal Cipok, PhD

Blood (2013) 122 (21): 3973.

https://doi.org/10.1182/blood.V122.21.3973.3973

Published: 2013

Journal Articles

Blocking Protein Secretion and Degradation Is a Novel Treatment Strategy For Malignant Cells With High Protein Load

Eric Lowe, Rebecca Maglathlin, Alana Lerner, Ph.D, Jack Taunton, PhD, Christopher J. Kirk, Ph.D, Shirin Arastu-Kapur, Ph.D

Blood (2013) 122 (21): 4439.

https://doi.org/10.1182/blood.V122.21.4439.4439

Published: 2013

Journal Articles

Brain-Derived Neurotrophic Factor Enhances Osteoclastogenesis in Multiple Myeloma via Upregulation of RANKL/OPG Ratio Both in Vitro and in a Murine Model of Myeloma Bone Disease

Li-Sha Ai, Chun-Yan Sun, Tao Guo, Ya-Dan Wang, Lu Zhang, You Qin, Lei Chen, Han Yan, Wei Zeng, Jun Fang, Yu Hu

Blood (2012) 120 (21): 568.

https://doi.org/10.1182/blood.V120.21.568.568

Published: 2012

Journal Articles

The Antimalarial Agent Artesunate Overcomes Bortezomib Resistance in Myeloma Cell Lines Through Non-Caspase Mediated Apoptosis

Xenofon Papanikolaou, MD, Ruslana Tytarenko, Tarun K. Garg, PhD, Sarah K. Johnson, PhD, Erming Tian, Senu Apewokin, MD, Bart Barlogie, MD, Joshua Epstein, DSc, Christoph Heuck, MD

Blood (2012) 120 (21): 4015.

https://doi.org/10.1182/blood.V120.21.4015.4015

Published: 2012

Journal Articles

MiR-15a and Mir-16-1 Affects the Angiogenesis of Multiple Myeloma by Targeting VEGF-A

Chunyan Sun, Yu Hu, Xiaomei She, Zhangbo Chu, Jun Fang, Lei Chen

Blood (2010) 116 (21): 4039.

https://doi.org/10.1182/blood.V116.21.4039.4039

Published: 2010

Journal Articles

Cardamonin, a Novel Blocker of STAT3 and Nuclear Factor-κB Activation, Suppresses Proliferation, Arrests Cell Cycle, and Potentiates Apoptosis In Human Multiple Myeloma Cells

You Qin, Chunyan Sun, Tao Guo, Yadan Wang, Lu Zhang, Lei Chen, Xiaomei She, Lisha Ai, Han Yan, Nicholas Miller Gregg, Jun Fang, Yu Hu

Blood (2010) 116 (21): 1820.

https://doi.org/10.1182/blood.V116.21.1820.1820

Published: 2010

Journal Articles

Novel Histone Deacetilase (HDAC) Inhibitors: In Vitro Effects on Leukemic Cells

Maria Rosaria Ricciardi, PhD, Roberto Licchetta, Paola Bergamo, Stefano Iacovelli, Andrea Miele, Maria Teresa Petrucci, MD, Michele Milella, MD, Claudio Pisano, PhD, Agostino Tafuri, MD

Blood (2010) 116 (21): 4946.

https://doi.org/10.1182/blood.V116.21.4946.4946

Published: 2010

Journal Articles

A New Xenograft Model for Studying Multiple Myeloma and Drug Response

Varda Deutsch, PhD, Yona Farnoushi, MSc, Michal Cipok, PhD, Sigi Kay, PhD, Elizabeth Naparstek, MD, Ronald Goldstein, PhD

Blood (2010) 116 (21): 4073.

https://doi.org/10.1182/blood.V116.21.4073.4073

Published: 2010

Journal Articles

Preclinical Approach to Sensitize Multiple Myeloma Cells: Combination of the MEK Inhibitor PD0325901 with ABT-737 or Mevinolin.

Maria Rosaria Ricciardi, Elisabetta Calabrese, Michele Milella, Paola Bergamo, Samantha Decandia, Cinzia De Benedictis, Robin Foà, Agostino Tafuri, Maria Teresa Petrucci

Blood (2009) 114 (22): 1842.

https://doi.org/10.1182/blood.V114.22.1842.1842

Published: 2009

Journal Articles

Lenalidomide IS Able to Restore Immune SYSTEM IN MULTIPLE MYELOMA PATIENTS.

Annalisa Chiarenza, Nunziatina Parrinello, Piera La Cava, Eleonora Spina, Daniele Tibullo, Cesarina Giallongo, Maide Cavalli, Alessandra Romano, Paolo Fiumara, Giuseppe A Palumbo, Francesco Di Raimondo

Blood (2009) 114 (22): 4909.

https://doi.org/10.1182/blood.V114.22.4909.4909

Published: 2009

NARROW

Profiling the Cell Surface Landscape of Proteasome Inhibitor-Treated and -Resistant Multiple Myeloma to Guide Immunotherapy Targeting, Diagnosis, and Biology

20(S)-Protopanaxatriol Promotes Fatty Acid-Induced ER Stress and Apoptosis in Multiple Myeloma By Down-Regulating SCD1 Expression

Vactosertib, a TGF-ß Receptor I Kinase/ALK5 Inhibitor, Diminishes Tumor Progression and Bone Disease in a Mouse Model of Multiple Myeloma and Overcomes Resistance to Proteasome Inhibitors

HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo

Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of E x V ivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells

SL-801, a Novel, Reversible Inhibitor of Exportin-1 (XPO1) / Chromosome Region Maintenance-1 (CRM1) with Broad and Potent Anti-Cancer Activity

Leukemia Cell Xenograft in Ovo Enables Real-Time Testing of Response to Therapy

Evaluation of Anti-Neoplastic Effects of a New Hemostatic Agent Ankaferd Blood Stopper on Myeloma Cell Line and Plasmocytoma Development in Balb/c Mice: Results of the First in Vitro and in Vivo Study

BCL6 Dose Not Negatively Regulate DNA Damage Response Genes in Multiple Myeloma Cells

Combined Carfilzomib and Selective PI3Kδ Inhibition (TGR1202) Results In Enhanced Myeloma Cell Apoptosis

New Xenograft Method For Studying Leukemia and Drug Response In Turkey Embryos

Blocking Protein Secretion and Degradation Is a Novel Treatment Strategy For Malignant Cells With High Protein Load

Brain-Derived Neurotrophic Factor Enhances Osteoclastogenesis in Multiple Myeloma via Upregulation of RANKL/OPG Ratio Both in Vitro and in a Murine Model of Myeloma Bone Disease

The Antimalarial Agent Artesunate Overcomes Bortezomib Resistance in Myeloma Cell Lines Through Non-Caspase Mediated Apoptosis

MiR-15a and Mir-16-1 Affects the Angiogenesis of Multiple Myeloma by Targeting VEGF-A

Cardamonin, a Novel Blocker of STAT3 and Nuclear Factor-κB Activation, Suppresses Proliferation, Arrests Cell Cycle, and Potentiates Apoptosis In Human Multiple Myeloma Cells

Novel Histone Deacetilase (HDAC) Inhibitors: In Vitro Effects on Leukemic Cells

A New Xenograft Model for Studying Multiple Myeloma and Drug Response

Preclinical Approach to Sensitize Multiple Myeloma Cells: Combination of the MEK Inhibitor PD0325901 with ABT-737 or Mevinolin.

Lenalidomide IS Able to Restore Immune SYSTEM IN MULTIPLE MYELOMA PATIENTS.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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