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Journal Articles

Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin

Eric R. Henry, Belhu Metaferia, Quan Li, Julia Harper, Robert B. Best, Kristen E. Glass, Troy Cellmer, Emily B. Dunkelberger, Anna Conrey, Swee Lay Thein, H. Franklin Bunn, William A. Eaton

Blood (2021) 138 (13): 1172–1181.

DOI: https://doi.org/10.1182/blood.2021012070

Published: 2021

Includes: Supplemental data

Journal Articles

Sickle marrow: double, double toil and trouble

Mark C. Walters

Blood (2020) 135 (23): 2017–2018.

DOI: https://doi.org/10.1182/blood.2020005114

Published: 2020

Journal Articles

2'-O-Methoxyethyl Splice-Switching Oligos to Reverse Splicing from IVS2-745 β-Thalassemia Patient Cells: A Foundation for Potential Therapies

Blood (2019) 134 (Supplement_1): 2244.

DOI: https://doi.org/10.1182/blood-2019-127017

Published: 2019

Journal Articles

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

Minke A.E. Rab, MD, Richard van Wijk, PhD, Celeste K. Kanne, BA, Brigitte A. van Oirschot, Jennifer Bos, Camille Boisson, Maite E. Houwing, MD, Jorn J. Gerritsma, MD, Karin Fijnvandraat, MD PhD, Celine Renoux, PhD, Marije Bartels, MD PhD, Erfan Nur, MD PhD, Marjon H. Cnossen, MD PhD, Philippe Joly, PhD, Romain Fort, MD, Philippe Connes, PhD, Eduard J. van Beers, MD PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 2275.

DOI: https://doi.org/10.1182/blood-2019-128870

Published: 2019

Journal Articles

Unusually High Prevalence of Silent Stroke and Cerebral Vasculopathy in Hemoglobin SC Disease

Bindu K Sathi, MD, Yoshida Yilin, PhD, Michael Raymond Weaver, BA, Lila Wahidi Nolan, MD, Barbara Gruner, MD, Cara Hirner, RN, BSN, Vinod V. Balasa, MBBS, Talissa Altes, MD, Carlos Leiva Salinas, MD

Blood (2019) 134 (Supplement_1): 2276.

DOI: https://doi.org/10.1182/blood-2019-122975

Published: 2019

Journal Articles

Analysis of the Eligibility of Patients with Sickle Cell Disease for Palliative Care

Pedro de Oliveira Toro da Silva, Cristina Bueno Terzi, MD PhD, Antonio Luis Eiras Falcão, MD PhD, Sara T Olalla Saad, PhD, Fernando Ferreira Costa, MD PhD, Paula De Melo Campos, MD

Blood (2019) 134 (Supplement_1): 4681.

DOI: https://doi.org/10.1182/blood-2019-128884

Published: 2019

Journal Articles

Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

Nicolas Hebert, Rakotoson Marie Georgine, PhD, Gwellaouen Bodivit, Etienne Audureau, MD PhD, Nadia Oubaya, Sadaf Pakdaman, Mehdi Sakka, Gaetana Di Liberto, PhD, Philippe Chadebech, PhD, Benoît Vingert, PhD, France Pirenne, MD PhD, Frédéric Galactéros, MD PhD, Marie Cambot, PhD, Pablo Bartolucci, MD PhD

Blood (2019) 134 (Supplement_1): 1008.

DOI: https://doi.org/10.1182/blood-2019-126727

Published: 2019

Journal Articles

360 o View of a Day Hospital Program Performing Exchange Transfusion and Outpatient Pain Management on Adults with Sickle Cell Disease

Natasha Wright, CRNP, Susan M. Sylvester, RN, Gregory J Kato, MD, Enrico Novelli, MD, Maria Nepa, PA-C, Jude C Jonassaint, RN, Laura De Castro, MD MHSc

Blood (2019) 134 (Supplement_1): 5873.

DOI: https://doi.org/10.1182/blood-2019-122397

Published: 2019

Journal Articles

Integrated Anemia Detection and Hemoglobin Variant Identification Using Point-of-Care Microchip Electrophoresis

Ran An, PhD, Muhammad Noman Hasan, MS, Yuncheng Man, Umut A. Gurkan, PhD

Blood (2019) 134 (Supplement_1): 378.

DOI: https://doi.org/10.1182/blood-2019-126096

Published: 2019

Journal Articles

Unswitched Memory B Cell Deficiency Is Associated with Acute Chest Syndrome and Stroke in Sickle Cell Disease

Sameera Bhamidipati, MA, Venee N. Tubman, MD, Norma Estrada, Charles Minard, PhD

Blood (2019) 134 (Supplement_1): 1010.

DOI: https://doi.org/10.1182/blood-2019-128575

Published: 2019

Journal Articles

The Effect of Crizanlizumab Plus Standard of Care (SoC) Versus Soc Alone on Renal Function in Patients with Sickle Cell Disease and Chronic Kidney Disease: A Randomized, Multicenter, Open-Label, Phase II Study (STEADFAST)

Kenneth I. Ataga, MD, Santosh L. Saraf, MD, Vimal K. Derebail, MD, Claire C. Sharpe, Adlette Inati, MD, Jeffrey D. Lebensburger, DO, MSPH, Laurie DeBonnett, MD, Shirong Zhang, Pablo Bartolucci, MD PhD

Blood (2019) 134 (Supplement_1): 1018.

DOI: https://doi.org/10.1182/blood-2019-124823

Published: 2019

Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

Blood (2019) 134 (Supplement_1): 615.

DOI: https://doi.org/10.1182/blood-2019-123355

Published: 2019

Journal Articles

Phase 1 Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of FT-4202, an Allosteric Activator of Pyruvate Kinase-R, in Healthy and Sickle Cell Disease Subjects

Theodosia A. Kalfa, MD PhD, Frans A Kuypers, PhD, Marilyn J. Telen, MD, Punam Malik, MD, Diamantis G. Konstantinidis, PhD BSc, Jeremy H. Estepp, MD, Hyon J. Kim, MD PhD, Santosh L. Saraf, MD, Lindsey Wilson, Maria D Ribadeneira, PhD, Sanjeev Forsyth, Patricia Schroeder, Adam Drake, Olga Polyanskaya, Patrick Kelly, MD, Lukasz Biernat, MD

Blood (2019) 134 (Supplement_1): 616.

DOI: https://doi.org/10.1182/blood-2019-121889

Published: 2019

Journal Articles

Complications of Extra Fluid Therapy (Hyperhydration) in Sickle Cell Patients during Vaso-Occlusive Painful Crisis

Aafke E. Gaartman, MD, Ajab K. Sayedi, BSc, Charlotte F.J. Van Tuijn, MPH, PhD, Harriet Heijboer, MD PhD, Tanja Netelenbos, MD PhD, Bart J. Biemond, MD PhD, Erfan Nur, MD PhD

Blood (2019) 134 (Supplement_1): 1024.

DOI: https://doi.org/10.1182/blood-2019-130248

Published: 2019

Journal Articles

The Relationships between Target Gene Transduction, Engraftment of HSCs and RBC Physiology in Sickle Cell Disease Gene Therapy

Melissa Bonner, PhD, Julie Kanter, MD, Elizabeth Macari, PhD, Ricky Lane, Gretchen Lewis, BMBS, Paige Coles, Sarah Kassenaar, Sai Mynampati, MS, Robert Schulze, Madison Hebert, Mark C. Walters, MD, Alexis A. Thompson, MD MPH, Mohammed Asmal, MD PhD, John F. Tisdale, MD, Francis J. Pierciey, Jr.

Blood (2019) 134 (Supplement_1): 206.

DOI: https://doi.org/10.1182/blood-2019-129124

Published: 2019

Journal Articles

LIC-R2 Values Predict Severity of SCD: Baseline Data from Licnet-S

Rosario Di Maggio, MD, Angela Vitrano, PhD, Carmelo Fidone, MD, Alessandra Quota, MD, Daniela Fiorino, MD, Calogera Gerardi, MD, Saveria Campisi, MD, Lorenzo Tesé, MD, Vincenzo Santoro, MD, Barone Rita, MD, Giangreco Antonino, MD, Paolo Rigano, Lorella Pitrolo, MD, Aurelio Maggio, MD

Blood (2019) 134 (Supplement_1): 4810.

DOI: https://doi.org/10.1182/blood-2019-124728

Published: 2019

Journal Articles

EDIT-301: An Experimental Autologous Cell Therapy Comprising Cas12a-RNP Modified mPB-CD34+ Cells for the Potential Treatment of SCD

Edouard De Dreuzy, PhD, Jack Heath, John A Zuris, PhD, Patricia Sousa, Ramya Viswanathan, Sean Scott, Jen Da Silva, Terence Ta, PhD, Stacy Capehart, PhD, Tongyao Wang, Cecilia Fernandez, PhD, Vic E Myer, PhD, Charles F Albright, PhD, Christopher J Wilson, PhD, Sandra Teixeira, PhD, Kai-Hsin Chang, PhD

Blood (2019) 134 (Supplement_1): 4636.

DOI: https://doi.org/10.1182/blood-2019-130256

Published: 2019

Journal Articles

Characterization of Bulk Rigidity of Rigid Red Blood Cell Populations in Sickle Cell Patients Using a Parameterization Model of Ektacytometry

Mario Gutierrez, Mark Shamoun, MD, Tyler Tanski, Lola Eniola-Adefeso, PhD MS

Blood (2019) 134 (Supplement_1): 3572.

DOI: https://doi.org/10.1182/blood-2019-131638

Published: 2019

Journal Articles

Development of a Low-Cost Electrical Impedance-Based Microflow Cytometer

Darryl Dieujuste, BS,MS, Jia Liu, E. Du, PhD, Ofelia A. Alvarez, MD

Blood (2019) 134 (Supplement_1): 4665.

DOI: https://doi.org/10.1182/blood-2019-129068

Published: 2019

Journal Articles

Potential Impact of Sickle Hemoglobin Concentration on Survival Among Patients with Renal Medullary Carcinoma and Sickle Cell Trait

Marcus A. Carden, MD, Jonathan Metts, MD, John M. McCarty, MD, Sarah Mitchell, MD, Bradley Carthon, MD PhD, David A. Siegel, MD, Louis Rapkin, MD, Morgan L. McLemore, MD

Blood (2019) 134 (Supplement_1): 4843.

DOI: https://doi.org/10.1182/blood-2019-125088

Published: 2019

NARROW

Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin

Sickle marrow: double, double toil and trouble

2'-O-Methoxyethyl Splice-Switching Oligos to Reverse Splicing from IVS2-745 β-Thalassemia Patient Cells: A Foundation for Potential Therapies

The Oxygenscan Provides Clinically Relevant Biomarkers for Treatment Efficacy That Are Associated with Frequency of Vaso-Occlusive Crisis in Sickle Cell Disease

Unusually High Prevalence of Silent Stroke and Cerebral Vasculopathy in Hemoglobin SC Disease

Analysis of the Eligibility of Patients with Sickle Cell Disease for Palliative Care

Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

360 o View of a Day Hospital Program Performing Exchange Transfusion and Outpatient Pain Management on Adults with Sickle Cell Disease

Integrated Anemia Detection and Hemoglobin Variant Identification Using Point-of-Care Microchip Electrophoresis

Unswitched Memory B Cell Deficiency Is Associated with Acute Chest Syndrome and Stroke in Sickle Cell Disease

The Effect of Crizanlizumab Plus Standard of Care (SoC) Versus Soc Alone on Renal Function in Patients with Sickle Cell Disease and Chronic Kidney Disease: A Randomized, Multicenter, Open-Label, Phase II Study (STEADFAST)

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

Phase 1 Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of FT-4202, an Allosteric Activator of Pyruvate Kinase-R, in Healthy and Sickle Cell Disease Subjects

Complications of Extra Fluid Therapy (Hyperhydration) in Sickle Cell Patients during Vaso-Occlusive Painful Crisis

The Relationships between Target Gene Transduction, Engraftment of HSCs and RBC Physiology in Sickle Cell Disease Gene Therapy

LIC-R2 Values Predict Severity of SCD: Baseline Data from Licnet-S

EDIT-301: An Experimental Autologous Cell Therapy Comprising Cas12a-RNP Modified mPB-CD34+ Cells for the Potential Treatment of SCD

Characterization of Bulk Rigidity of Rigid Red Blood Cell Populations in Sickle Cell Patients Using a Parameterization Model of Ektacytometry

Development of a Low-Cost Electrical Impedance-Based Microflow Cytometer

Potential Impact of Sickle Hemoglobin Concentration on Survival Among Patients with Renal Medullary Carcinoma and Sickle Cell Trait

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American Society of Hematology

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American Society of Hematology

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