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Journal Articles

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability

Zhaowei Tu, Chen Wang, Ashley K. Davis, Mengwen Hu, Chuntao Zhao, Mei Xin, Q. Richard Lu, Yi Zheng
Journal: Blood
Blood (2021) 138 (3): 221–233.
https://doi.org/10.1182/blood.2020009997
Published: 2021
Includes: Supplemental data
Journal Articles

Microenvironmental Signatures Reveal Biological Subtypes of Diffuse Large B-Cell Lymphoma (DLBCL) Distinct from Tumor Cell Molecular Profiling

Leandro Cerchietti, MD, Giorgio Inghirami, MD, Nikita Kotlov, PhD, Viktor Svekolkin, PhD, Alexander Bagaev, PhD, Felix Frenkel, PhD, Maria Victoria Revuelta, PhD, Jude M Phillip, PhD, Maria Teresa Cacciapuoti, MS, Sarah C. Rutherford, MD, Peter Martin, FRCPC, MD MS, John P. Leonard, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 656.
https://doi.org/10.1182/blood-2019-128889
Published: 2019
Journal Articles

Cells Deficient in the Shwachman-Diamond Syndrome Protein SBDS or the Diamond-Blackfan Anemia Protein RPS19 Have Impaired Homologous Recombination

Elif Asik, PhD, Nimrat Chatterjee, PhD, Alison A. Bertuch, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 104.
https://doi.org/10.1182/blood-2019-128953
Published: 2019
Journal Articles

Integrated Genomics and Functional Validation Identifies a Global Kinase Gene Signature Impacting Genome Stability in Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Chengcheng Liao, MD PhD, Jialan Shi, MD PhD, Mychell Neptune, Chandraditya Chakraborty, PhD, Mehmet Kemal Samur, PhD, Rao Prabhala, Masood A. Shammas, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 363.
https://doi.org/10.1182/blood-2019-129069
Published: 2019
Journal Articles

Genetic Variants of ATM & Non-Homologous End Joining Pathway Genes in Acute Myeloid Leukemia: A South India Case-Control Study

Sugunakar Vuree, M.Sc., PhD, Anuradha Cingeetham, M.Sc.,PhD, Dunna Nageswara Rao, M.Sc.,PhD, Manjula Gorre, M.Sc.,PhD, Sudha Sinha, MBBS.MD, Raghunadharao Digumarthi, Sr., MBBS.MDDM,FAPAS, Vishnupriya Satti, M.Sc.,PhD, Sadashivudu Gundeti, DM, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5076.
https://doi.org/10.1182/blood-2019-127860
Published: 2019
Journal Articles

Aneuploidy Is Associated with Inferior Survival in Relapsed Refractory Multiple Myeloma Patients

J Christine Ye, MDMSc, Liying Chen, Jason Chen, MD, Brian Parkin, Avery Polk, Malathi Kandarpa, PhD, Craig E. Cole, MD, Erica L. Campagnaro, MD, Dan Robinson, PhD, Yi-Mi Wu, Moshe Talpaz, MD, Jennifer Yesil, Daniel Auclair, P. Leif Bergsagel, MD, Arul Chinnaiyan, MD, Veerabhadran Baladandayuthapani
Journal: Blood
Blood (2019) 134 (Supplement_1): 4360.
https://doi.org/10.1182/blood-2019-124135
Published: 2019
Journal Articles

Understanding the Mechanisms Driving Genomic Instability in Adult T-Cell Leukemia/Lymphoma

Advaitha Madireddy, PhD, Angelica Barreto-Galvez, B. Hilda Ye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5042.
https://doi.org/10.1182/blood-2019-121565
Published: 2019
Journal Articles

Germinal Predisposition in Myelodysplastic Syndromes in Young Adults without a Preexisting Disorder or Organ Dysfunction: Identification of Deleterious Variants in Microsatellite Instability Genes

Tzu Hua Chen-Liang, Ana M Hurtado López, María Zurdo, Esperanza Such, Raul Teruel-Montoya, PhD, Laura Palomo, María-José Jimenez, MD, Rafael Andres del Orbe Barreto, Blanca Navarro, MD PhD, Félix López Cadenas, MD, Eduardo José Salido, MD, Carmen Benet, MD, Begoña Muiña, Raquel de Oña, Nuria de Haro, Fernando Ramos, Montserrat Arnan Sangerman, Francisca Maria Hernandez, MD, Francisco José Ortuño, Leonor Senent, Ana Vicente, María Díez-Campelo, MD PhD, Maria Lourdes Hermosin, MD, Teresa Bernal Del Castillo, MD PhD, Mar Tormo, MD PhD, Beatriz Arrizabalaga, Blanca Xicoy, MD MSc, José Cervera, MD PhD, Francesc Sole, PhD, Guillermo F. Sanz, MD PhD, Andres Jerez
Journal: Blood
Blood (2019) 134 (Supplement_1): 4226.
https://doi.org/10.1182/blood-2019-127204
Published: 2019
Journal Articles

MCL1 Inhibitors in Multiple Myeloma

Karin Vanderkerken, PhD, Kim De Veirman, Ken Maes, Eline Menu, PhD, Elke De Bruyne, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-12.
https://doi.org/10.1182/blood-2019-121104
Published: 2019
Journal Articles

PARP Inhibition Sensitize BCR-ABL1 Positive Cel

Haruka Hiroki, MD, Masatoshi Takagi, MD PhD, Yuko Ishi, MD, Jinhua Piao, Tomohiro Morio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3367.
https://doi.org/10.1182/blood-2019-127853
Published: 2019
Journal Articles

TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins

Ashwin Kishtagari, MBBS, Yihong Guan, PhD, Cassandra M Kerr, MS, Hassan Awada, MD, Jibran Durrani, Edward F Greenberg, MD, Xiaorong Gu, PhD, Feng Pan, PhD, Valeria Visconte, PhD, Dewen You, PhD, Guangbo Qu, PhD, Amy C Graham, BS, MS, Bartlomiej P. Przychodzen, Thomas Laframboise, PhD, Hideki Makishima, MD PhD, Daniel Gackowski, PhD, Ryszard Ólinski, Professor, Yu-Wei Cheng, PhD, Mikkael A. Sekeres, MD MS, Mingjiang Xu, MD PhD, Babal K. Jha, PhD, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1200.
https://doi.org/10.1182/blood-2019-132005
Published: 2019
Journal Articles

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

Manuela Mancini, PhD, Sara De Santis, Dr, Cecilia Monaldi, Dr, Luana Bavaro, Dr, Margherita Martelli, Dr, Gabriele Gugliotta, MD PhD, Fausto Castagnetti, MD PhD, Gianantonio Rosti, MD, Maria Chiara Fontana, PhD, Samantha Bruno, Dr, Elisa Dan, PhD, Barbara Sinigaglia, Dr, Alessandra Iurlo, MD PhD, Nicola Orofino, MD, Elisabetta Abruzzese, MD, Marzia Salvucci, MD, Patrizia Pregno, Antonella Gozzini, MD, Monica Crugnola, MD, Francesco Albano, MD, Massimiliano Bonifacio, MD, Elisabetta Calistri, MD, Mario Tiribelli, Gianni Binotto, MD, Annalisa Imovilli, Elena Trabacchi, MD, Sara Galimberti, MD PhD, Claudia Baratè, Elena Tenti, Michele Baccarani, MD, Giovanni Martinelli, MD, Michele Cavo, Simona Soverini, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4142.
https://doi.org/10.1182/blood-2019-126500
Published: 2019
Journal Articles

DNA Polymerases Pol θ/Pol η Involved in Error-Prone DNA Repair Are Highly Expressed in Multiple Myeloma and Upregulated By DNA Damage

Masanobu Sunaga, Master, Graduate Student, Tsukasa Oda, PhD, Eiko Yamane, Master, Graduate Student, Rei Ishihara, Master, Graduate Student, Yuki Murakami, Master, Graduate Student, Saki Watanabe, Master, Yuta Asao, Graduate Student, Yuta Masuda, Master, Hisashi Takei, MD, Nobuhiko Kobayashi, MD PhD, Yohei Osaki, MD PhD, Gotoh Nanami, Tetsuhiro Kasamatsu, PhD, Hiromi Koiso, MD PhD, Makiko Takizawa, MD PhD, Hiroaki Shimizu, MD PhD, Takuma Ishizaki, MD PhD, Yoshiyuki Ogawa, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MD PhD, Takayuki Saitoh, MD PhD, Hirokazu Murakami, MD PhD, Hiroshi Handa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4364.
https://doi.org/10.1182/blood-2019-125163
Published: 2019
Journal Articles

1q21 Gain May Challenge the Role of t(4;14) As an Adverse Prognostic Marker of Multiple Myeloma

Chenxing Du, An Gang, MD, Yan Xu, Xuehan Mao, MD, Yuting Yan, Jiahui Liu, Huishou Fan, Weiwei Sui, Shuhui Deng, MD, Li Zengjun, Chengwen Li, Shuhua Yi, MD, Mu Hao, Dehui Zou, MD, Fenghuang Zhan, MD PhD, Yu-Tzu Tai, PhD, Kenneth C. Anderson, MD, Lugui Qiu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4343.
https://doi.org/10.1182/blood-2019-129739
Published: 2019
Journal Articles

The Spectrum of Exomic Mutation in Elderly Myeloma Differs Substantially from Patients at Younger Ages Consistent with a Different Evolutionary Trajectory to Full Blown Disease Based on Age of Onset

Louis Williams, MD MBA, Eileen M Boyle, MD MSc, Faith E. Davies, MD, Brian A Walker, PhD, Cody Ashby, PhD, Michael A Bauer, PhD, Christopher P. Wardell, PhD MSc, BSc, Erin Flynt, Anjan Thakurta, Gareth Morgan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4346.
https://doi.org/10.1182/blood-2019-130079
Published: 2019
Journal Articles

High-Throughput Immunofluorescence and Electron Tomography to Characterize Centrosomal Aberrations in Plasma Cell Neoplasia

Tobias Dittrich, MD, Martin Schorb, Isabella Haberbosch, MD, Elena Bausch, PhD, Mandy Börmel, Marco Cosenza, PhD, Hartmut Goldschmidt, MD, Carsten Müller-Tidow, MD, Marc S Raab, MD PhD, Ute Hegenbart, MD, Stefan O. Schönland, MD, Yannick Schwab, PhD, Alwin Krämer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3077.
https://doi.org/10.1182/blood-2019-130713
Published: 2019
Journal Articles

This Is a Title in Title Case: Prediction of CML Evolution By Telomere Length Analysis at the Single-Chromosome Level

Jingyuan Lu, Yingxing Zhou, Xiaomei Yan, Quanyi Lu
Journal: Blood
Blood (2019) 134 (Supplement_1): 2937.
https://doi.org/10.1182/blood-2019-126895
Published: 2019
Journal Articles

Macrophages Promote DNA Repair of Double Strand Break in Multiple Myeloma Cells By Non-Homologous End Joining(NHEJ), Nevertheless Decrease Its Accuracy

Mengmeng Dong, Enfan Zhang, Haimeng Yan, MD, Ruyi Xu, He Huang, Anyong Xie, Zhen Cai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3087.
https://doi.org/10.1182/blood-2019-126753
Published: 2019
Journal Articles

Significantly Upregulated Thrombo-Inflammatory Genes Are Normoregulated or Significantly Downregulated during Treatment with Interferon-Alpha2 in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2978.
https://doi.org/10.1182/blood-2019-131698
Published: 2019
Journal Articles

High Burden of Clonal Hematopoiesis in First Responders Exposed to the World Trade Center Disaster

Sakshi Jasra, MD, Orsi Giricz, PhD, Rachel Zeig-Owens, M.P.H, David Goldfarb, M.P.H, Angelica Barreto-Galvez, Kith Pradhan, PhD, Jiahao Chen, PhD, Gaurav S Choudhary, PhD, Srinivas Aluri, Tushar D Bhagat, PhD, Aditi Shastri, MD, Victor Thiruthuvanathan, M.S, Hiroki Goto, MD PhD, Jeannine Gerhardt, PhD, Shanisha Gordon, Arul Veerappan, PhD, Syed Hissam Haider, MD, Matthias Bartenstein, MD, George Nwankwo, Ola Landgren, MD PhD, Michael Weiden, MD, Frederick Fletcher, Lee Greenberger, PhD, Benjamin L. Ebert, MD PhD, Ulrich G. Steidl, MD PhD, Britta Will, PhD, Anna Nolan, MD MS, David Prezant, MD, Advaitha Madireddy, PhD, Amit Verma, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3720.
https://doi.org/10.1182/blood-2019-129276
Published: 2019