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Journal Articles

Overcoming a Critical Obstacle Towards Effective and Safe CAR T-Cell Therapeutics

Nandini Mondal, PhD, Mariana Silva, PhD, Ana Castano, MD, Marcela V. Maus, MD PhD, Robert Sackstein, MD PhD

Blood (2018) 132 (Supplement 1): 2056.

DOI: https://doi.org/10.1182/blood-2018-99-118675

Published: 2018

Journal Articles

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

Joshua Kellner, Stefan O. Ciurea, Amanda L. Olson, MD, Yago Nieto, MD PhD, Borje S Andersson, MDPhD, Joseph David Khoury, MD, Richard E. Champlin, MD, Stefan Nierkens, PhD, Jaap Jan Boelens, MD PhD, Bruce Blazar, MD, Simrit Parmar, MBBS

Blood (2017) 130 (Supplement 1): 3246.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3246.3246

Published: 2017

Journal Articles

O -Fucose and Fringe-Modified Recombinant Notch Peptides As Decoy Molecules to Promote Hematopoietic Progenitor Mobilization

Lan Zhou, MD, Shuiliang Yu, PhD, Weihuan Wang, MD PhD, Marwah Albakri, Seunghwan Lim, Chris Siebel, PhD BA, Hillard M Lazarus, MD, John Letterio, MD, Wei Xin, MD PhD

Blood (2017) 130 (Supplement 1): 1903.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1903.1903

Published: 2017

Journal Articles

GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes

Blair R. Anderson, BS, Melanie E. Garrett, MS, Karen L. Soldano, BS, Eugene P. Orringer, MD, James R. Eckman, MD, Ludmila Francescatto, PhD, Erica E. Davis, PhD, Mark T. Gladwin, MD, Victor R. Gordeuk, MD, Marilyn J. Telen, MD, Allison E. Ashley-Koch, PhD

Blood (2016) 128 (22): 269.

DOI: https://doi.org/10.1182/blood.V128.22.269.269

Published: 2016

Journal Articles

Identification of glycans on plasma-derived ADAMTS13

Fabian C. Verbij, Eva Stokhuijzen, Paul H. P. Kaijen, Floris van Alphen, Alexander B. Meijer, Jan Voorberg

Blood (2016) 128 (21): e51–e58.

DOI: https://doi.org/10.1182/blood-2016-06-720912

Published: 2016

Includes: Supplemental data

Journal Articles

Analysis of the Glycan Composition on Plasma Derived ADAMTS13 Employing Tandem Mass Spectrometry

Fabian Verbij, MSc, Eva Stokhuijzen, MSc, Floris van Alphen, Paul Kaijen, Alexander Meijer, PhD, Jan Voorberg, PhD

Blood (2015) 126 (23): 1069.

DOI: https://doi.org/10.1182/blood.V126.23.1069.1069

Published: 2015

Journal Articles

Fucosylated Antigen-Specific Cytotoxic T Lymphocytes Demonstrate Enhanced Killing of Leukemia Targets

Gheath Alatrash, DO, PhD, Mao Zhang, MPH, Na Qiao, PhD, Pariya Sukhumalchandra, BS, Madhushree Zope, Anne V. Philips, PhD, Alexander Perakis, BA, Lisa St. John, PhD, Maria R. Khouri, Victor Gall, MD, Karen C. Dwyer, PhD, Jodie Polan, MS, Jeffrey J. Molldrem, MD, Elizabeth J. Shpall, MD, Elizabeth A. Mittendorf, MD PhD

Blood (2015) 126 (23): 1888.

DOI: https://doi.org/10.1182/blood.V126.23.1888.1888

Published: 2015

Journal Articles

Modulation of the β2-Integrin Axis in Inflammatory Cell Trafficking By Fucosylated Ligands

Alex Buffone, Jr., Mehrab Nasirikenari, PhD, Sriram Neelamegham, Joseph T. Lau, PhD

Blood (2015) 126 (23): 4603.

DOI: https://doi.org/10.1182/blood.V126.23.4603.4603

Published: 2015

Journal Articles

IgG Alloantibodies Against RBC Induced By Pregnancy or Transfusion Have Unique Glycosylation Patterns Which Correlate with Clinical Outcome of Hemolytic Disease of the Fetus or Newborn

Myrthe Elisabeth Sonneveld, MD, Rosina Plomp, Jon Admiraal, Carolien Koeleman, Agnes Hipgrave-Ederveen, Joke Koelewijn, PhD, Peter Ligthart, Masja De Haas, Prof, MD, Manfred Wuhrer, Prof, C. Ellen Van der Schoot, Prof, MD, Gestur Vidarsson, PhD

Blood (2015) 126 (23): 660.

DOI: https://doi.org/10.1182/blood.V126.23.660.660

Published: 2015

Journal Articles

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

Lan Zhou, MD PhD, Weihuan Wang, MD PhD, Grant Zimmerman, Jay Myers, MS, Yuanshuai Huang, MD PhD, Vionnie W.C. Yu, PhD, Dan Huang, MD PhD, Shuiliang Yu, PhD, Yiwei Wang, MD PhD, Xiaoran Huang, MD, Jeongsup Shim, PhD, Minhong Yan, PhD, John Lowe, MD, Wei Xin, MD PhD, Pamela Stanley, PhD BSc, David T. Scadden, MD, Alex Y Huang, MD PhD, Christian W. Siebel, PhD

Blood (2014) 124 (21): 652.

DOI: https://doi.org/10.1182/blood.V124.21.652.652

Published: 2014

Journal Articles

MEN1112, a Novel Humanized De-Fucosylated Monoclonal Antibody with High Affinity and Specificity for Bst1/CD157 Antigen and Enhanced CD16 Binding

Dee Aud, Rachel Dusek, PhD, Arnima Bisht, PhD, Sudha Swaminithan, Rahel Awdew, Michael Trang, San Lin Lou, Stefano Manzini, Alfredo Martinez Mogarra, Alessandro Bressan, Jon Terrett, PhD, Monica Binaschi

Blood (2014) 124 (21): 3607.

DOI: https://doi.org/10.1182/blood.V124.21.3607.3607

Published: 2014

Journal Articles

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

Rick Kapur, Iwan Kustiawan, Anne Vestrheim, Carolien A. M. Koeleman, Remco Visser, Helga K. Einarsdottir, Leendert Porcelijn, Dave Jackson, Belinda Kumpel, André M. Deelder, Dennis Blank, Björn Skogen, Mette Kjaer Killie, Terje E. Michaelsen, Masja de Haas, Theo Rispens, C. Ellen van der Schoot, Manfred Wuhrer, Gestur Vidarsson

Blood (2014) 123 (4): 471–480.

DOI: https://doi.org/10.1182/blood-2013-09-527978

Published: 2014

Includes: Supplemental data

Journal Articles

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

Toshihiro Onishi, MD, Maria Berg, Robert Reger, Leonard Miller, PhD, Steve Wolpe, Lynnet Koh, MS, MBA, Richard Childs, MD

Blood (2013) 122 (21): 4499.

DOI: https://doi.org/10.1182/blood.V122.21.4499.4499

Published: 2013

Journal Articles

Low Expression Of The FUCA1 Gene Is An Adverse Prognostic Factor In Myeloma and Combined With High Sialyltransferase Gene Expression Identifies Patients At Increased Risk Of Early Disease Progression and Death

Siobhan Glavey, MD, Ping Wu, MBBS, MSc, Laura S Murillo, PhD, Catherine Loughrey, MSc, Aldo M Roccaro, MD, PhD, Gareth J Morgan, MD PhD, Irene M. Ghobrial, MD, Lokesh Joshi, PhD, Michael E O'Dwyer, MD, FRCPI, FRCPath

Blood (2013) 122 (21): 1864.

DOI: https://doi.org/10.1182/blood.V122.21.1864.1864

Published: 2013

Journal Articles

B-1239, a Novel Anti-BAFF-R Afucosylated Human Antibody, Promotes Potent Natural Killer Cell- Mediated Antibody Dependent Cellular Cytotoxicity In Chronic Lymphocytic Leukemia Cells In- Vitro and Depletion Of Circulating Leukemic CLL B Cells In-Vivo

Emily M. McWilliams, B.S., Carolyn Cheney, B.S, Jeffrey A. Jones, MD, MPH, Joseph M. M. Flynn, DO, MPH, Kami Maddocks, MD, Leslie A. Andritsos, MD, Heather Huet, PhD, Hermann Gram, Ph.D., Johan Baeck, MD, Natarajan Muthusamy, DVM, Ph.D, John C. Byrd, MD

Blood (2013) 122 (21): 4185.

DOI: https://doi.org/10.1182/blood.V122.21.4185.4185

Published: 2013

Journal Articles

Fucosylation Inhibitor, 2-Fluorofucose, Inhibits NF-κB Activation and Vaso-Occlusion In Transgenic Sickle Mice

John D Belcher, Ph.D., Chunsheng Chen, Julia Nguyen, Nicole M. Okeley, PhD, Peter D. Senter, PhD, Dennis R. Benjamin, PhD, Gregory M Vercellotti

Blood (2013) 122 (21): 730.

DOI: https://doi.org/10.1182/blood.V122.21.730.730

Published: 2013

Journal Articles

Displaced Niche Location and Decreased Quiescence Maintenance of Hematopoietic Stem Cells Due to Dysregulation of Notch Adhesive Interaction with Stromal Environment in Mice with Notch O-Fucosylation Deficiency

Weihuan Wang, PhD, Xiaoran Huang, MD, Jay Myers, Yiwei Wang, MD, PhD, Wei Xin, MD, PhD, Alex Y Huang, MD, PhD, Lan Zhou, MD, PhD

Blood (2012) 120 (21): 29.

DOI: https://doi.org/10.1182/blood.V120.21.29.29

Published: 2012

Journal Articles

Skewing towards Decreased Fc-Fucosylation of Platelet-Alloantibodies in Pregnancy

Rick Kapur, MD, MSc, Anne Vestrheim, Carolien AM Koeleman, Leendert Porcelijn, MD, Dave Jackson, Belinda Kumpel, PhD, André M Deelder, PhD, Terje E Michaelsen, PhD, Masja de Haas, MD, PhD, C. Ellen Van der Schoot, MD, PhD, Manfred Wuhrer, PhD, Gestur Vidarsson, PhD

Blood (2012) 120 (21): 3331.

DOI: https://doi.org/10.1182/blood.V120.21.3331.3331

Published: 2012

Journal Articles

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

Orla Rawley, Jamie O'Sullivan, Gudmundur Bergsson, PhD, Alain Chan, PhD, Rachel Therese McGrath, Maartje van den Biggelaar, Jan Voorberg, Vince Jenkins, PhD, James S O'Donnell, MD, PhD

Blood (2011) 118 (21): 2234.

DOI: https://doi.org/10.1182/blood.V118.21.2234.2234

Published: 2011

Journal Articles

Structural and Functional Characterization of Fucoidan and Its Procoagulant Effect in An Ex Vivo Model of Factor VIII-Inhibited Guinea Pigs

Michael Dockal, PhD, Werner Hoellriegl, Zhenqing Zhang, Susanne Till, PhD, Sabine Knappe, PhD, Michael Palige, PhD, Alexandra Schiviz, Hartmut J. Ehrlich, MD, Christina Szabo, Eva-Maria Muchitsch, Friedrich Scheiflinger, PhD

Blood (2011) 118 (21): 2262.

DOI: https://doi.org/10.1182/blood.V118.21.2262.2262

Published: 2011

NARROW

Overcoming a Critical Obstacle Towards Effective and Safe CAR T-Cell Therapeutics

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

O -Fucose and Fringe-Modified Recombinant Notch Peptides As Decoy Molecules to Promote Hematopoietic Progenitor Mobilization

GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes

Identification of glycans on plasma-derived ADAMTS13

Analysis of the Glycan Composition on Plasma Derived ADAMTS13 Employing Tandem Mass Spectrometry

Fucosylated Antigen-Specific Cytotoxic T Lymphocytes Demonstrate Enhanced Killing of Leukemia Targets

Modulation of the β2-Integrin Axis in Inflammatory Cell Trafficking By Fucosylated Ligands

IgG Alloantibodies Against RBC Induced By Pregnancy or Transfusion Have Unique Glycosylation Patterns Which Correlate with Clinical Outcome of Hemolytic Disease of the Fetus or Newborn

Loss of Notch Receptor-Ligand Engagement Leads to Increased Hematopoietic Stem and Progenitor Cell Egress and Mobilization

MEN1112, a Novel Humanized De-Fucosylated Monoclonal Antibody with High Affinity and Specificity for Bst1/CD157 Antigen and Enhanced CD16 Binding

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

Forced Fucosylation With ASC-101 Enhances The Binding Of Ex Vivo Expanded Human NK Cells To E-Selectin: A Novel Method To Improve The Homing Of Adoptively Transferred NK Cells To The Bone Marrow In Patients With Hematological Malignancies

Low Expression Of The FUCA1 Gene Is An Adverse Prognostic Factor In Myeloma and Combined With High Sialyltransferase Gene Expression Identifies Patients At Increased Risk Of Early Disease Progression and Death

B-1239, a Novel Anti-BAFF-R Afucosylated Human Antibody, Promotes Potent Natural Killer Cell- Mediated Antibody Dependent Cellular Cytotoxicity In Chronic Lymphocytic Leukemia Cells In- Vitro and Depletion Of Circulating Leukemic CLL B Cells In-Vivo

Fucosylation Inhibitor, 2-Fluorofucose, Inhibits NF-κB Activation and Vaso-Occlusion In Transgenic Sickle Mice

Displaced Niche Location and Decreased Quiescence Maintenance of Hematopoietic Stem Cells Due to Dysregulation of Notch Adhesive Interaction with Stromal Environment in Mice with Notch O-Fucosylation Deficiency

Skewing towards Decreased Fc-Fucosylation of Platelet-Alloantibodies in Pregnancy

Specific N- and O-Linked Carbohydrate Structures Mediate Von Willebrand Factor Interaction with Galectins -1 and -3

Structural and Functional Characterization of Fucoidan and Its Procoagulant Effect in An Ex Vivo Model of Factor VIII-Inhibited Guinea Pigs

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American Society of Hematology

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American Society of Hematology

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