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Journal Articles

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Hao Gu, Chiqi Chen, Xiaoxin Hao, Ni Su, Dan Huang, Yejun Zou, Shu-Hai Lin, Xianjun Chen, Denghao Zheng, Ligen Liu, Zhuo Yu, Li Xie, Yaping Zhang, Xiaoxiao He, Xiaoyun Lai, Xiaocui Zhang, Guo-Qiang Chen, Yuzheng Zhao, Yi Yang, Joseph Loscalzo, Junke Zheng
Journal: Blood
Blood (2020) 136 (5): 553–571.
DOI: https://doi.org/10.1182/blood.2019003940
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Optimum DTT Concentration and Treatment Time for CD38 Inactivation on RBCs Analyzed By a Newly-Devised Flow Cytometric Antibody Binding Assay

Hiroaki Furumaki, MD, Akihiro Takeshita, MD PhD, Chiaki Yamada, Harumi Fujihara, Keiko Ishizuka, Hiroki Shibata, Takahito Sinba, Momoko Sunako, Naoki Nemoto, Kaede Ino, Akari Ozawa, Hiroko Watanabe, Yukako Obata, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3692.
DOI: https://doi.org/10.1182/blood-2019-124289
Published: 2019
Journal Articles

A Novel Role for HMGN1 in Down Syndrome Acute Lymphoblastic Leukemia

Elyse C Page, BSc, Susan L Heatley, PhD MD, David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Paul Q Thomas, PhD, Deborah L. White, PhD FFSc (RCPA)
Journal: Blood
Blood (2019) 134 (Supplement_1): 1462.
DOI: https://doi.org/10.1182/blood-2019-126244
Published: 2019
Journal Articles

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, MD, Hui Zhang, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1506.
DOI: https://doi.org/10.1182/blood-2019-126738
Published: 2019
Journal Articles

Molecular MRD Monitoring Is Feasible in the Majority of Children with AML and Is Highly Predictive of Outcome: Results from the International MyeChild01 Study

Jelena Jovanovic, PhD, Nicola Potter, PhD, Anju Kanda, MSc, Claire Schwab, PhD, Aimee E Jackson, MSc, Richard Dillon, MA, PhD MRCP, FRCPath, Anna Lawson, BSc, Manohursingh Runglall, MSc, Paresh Vyas, MD PhD, Paul Virgo, Geoff Shenton, Nicholas Heaney, Beki James, MD, Katharine Patrick, MD, Persis J Amrolia, FRCP, FRCPath, PhD, Jean-Hugues Dalle, MD PhD, Gerard Michel, MD, Andrew S. Moore, MBBS,FRACP,PhD, Hélène Lapillonne, MD PhD, Claude Preudhomme, PharmD, PhD, Guy Leverger, MD, Owen P Smith, MD, Andre Baruchel, MD, Yves Bertrand, MD, Arnaud Petit, MD PhD, Keith Wheatley, DPhil, Pamela R. Kearns, PhDFRCPC, Christine J. Harrison, PhD FRCPath, Brenda Gibson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1393.
DOI: https://doi.org/10.1182/blood-2019-125257
Published: 2019
Journal Articles

Flotetuzumab (FLZ), an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells and CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment in Primary Refractory AML Patients

John E. Godwin, MD, Carmen Ballesteros-Merino, PhD, Nikhil Lonberg, Shawn Jensen, PhD, Tarsem Moudgil, Carlo B Bifulco, MD, Jon Wigginton, MD, John Muth, MS, Jan K Davidson-Moncada, MD PhD, Bernard Fox, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1410.
DOI: https://doi.org/10.1182/blood-2019-128485
Published: 2019
Journal Articles

Clinical and Laboratory Features Associated with Flow Cytometric CD49f Expression in Pediatric B Cell Acute Lymphoblastic Leukemia

Eric McGinnis, MD BSc, David Yang, BMLSc, Nina Rolf, MD PhD, Gregor S. D. Reid, PhD, Chinten J. Lim, PhD, Suzanne M. Vercauteren, MD PhD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 5209.
DOI: https://doi.org/10.1182/blood-2019-123590
Published: 2019
Journal Articles

Resistance to Axicabtagene Ciloleucel Therapy in T Cell/Histiocyte-Rich Large B Cell Lymphoma

Jonathan Trujillo, MD PhD, James Godfrey, MD, Michael R. Bishop, MD, Peter A. Riedell, MD, Justin Kline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5238.
DOI: https://doi.org/10.1182/blood-2019-131941
Published: 2019
Journal Articles

Expression of the Tigit/CD226/CD155 Receptors/Ligand System in Chronic Lymphocytic Leukemia

Francesca Arruga, PhD, Giulia Guerra, Denis Baev, PhD, Catherine Hoofd, PhD, Marta Coscia, MD PhD, Giovanni Francesco D'Arena, MD, Gianluca Gaidano, MD PhD, Richard R. Furman, MD, Silvia Deaglio, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5454.
DOI: https://doi.org/10.1182/blood-2019-128308
Published: 2019
Journal Articles

Activation of JAK2/STAT5 Pathway Reduces Expression Level of DNMT3a in MPN Cell Line

Jie Zhou, Aibin Liang, PhD, Shaoguang Li, Wenjun Zhang, Jianfei FU, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5394.
DOI: https://doi.org/10.1182/blood-2019-125434
Published: 2019
Journal Articles

Flow Cytometric Immunophenotyping Distinguishes Lymphoplasmacytic Lymphoma from Marginal Zone Lymphoma

Shi Hui Clarice Choong, MBBS, MRCP, Wee-Joo Chng, MBBS, PhD, Sanjay De Mel, BSc, BM, Te-Chih Liu, FRCPath, MBBS, MRCP, Bei Jenny Li, Li Mei Michelle Poon, Shir Ying Lee, FRCPath,MBBS,MRCP,, Hoon Chung Tae, Rebecca Teng, Seok Wei Stephrene Chan
Journal: Blood
Blood (2019) 134 (Supplement_1): 5253.
DOI: https://doi.org/10.1182/blood-2019-125241
Published: 2019
Journal Articles

Rituximab for Desensitization during HLA-Mismatched Stem Cell Transplantation in Patients with a Positive Donor Specific Anti-HLA Antibody: A Prospective Study

Ying-Jun Chang, Lan-Ping Xu, Yu Wang, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei Han, Yu-Qian Sun, Chenhua Yan, Fei-Fei Tang, Ming-Rui Huo, Xiao-Dong Mo, MD, Xiang-Yu Zhao, Kai-yan Liu, Xiao-Jun Huang
Journal: Blood
Blood (2019) 134 (Supplement_1): 5622.
DOI: https://doi.org/10.1182/blood-2019-129781
Published: 2019
Journal Articles

CRISPR/Cas9 Mediated ELANE Knock-out Restores Survival and Granulocytic Differentiation of HL60 Cells Expressing Mutant Neutrophil Elastase: Is Neutrophil Elastase a Dispensible Granulocyte Protease?

Vahagn Makaryan, MD, Isabella N. Archibald, Merideth L. Kelley, MS, Breanna Fletcher, BSc, David C. Dale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 435.
DOI: https://doi.org/10.1182/blood-2019-124988
Published: 2019
Journal Articles

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Yu Sun, BSc, MSc, PhD, Jayna J Mistry, BSc, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Christopher R Marlein, PhD, Anna Haestier, Cesar A. Gomez, MD PhD FRCPath, Christopher J Morris, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 689.
DOI: https://doi.org/10.1182/blood-2019-128268
Published: 2019
Journal Articles

Plasmatic Extracellular Vesicles in Acute Graft-Versus-Host Disease after Haplo-Identical Allografting with Post-Transplant Cyclophosphamide

Giuseppe Lia, PhD, Clara Di Vito, PhD, Marta Tapparo, PhD, Stefania Bruno, Elisa Zaghi, Michela Calvi, Lucia Brunello, Jacopo Mariotti, MD, Lorenzo Comba, Luisa Giaccone, Martina Fascì, Mario Boccadoro, Andrea Evangelista, MSc, Luca Castagna, MD, Giovanni Camussi, Domenico Mavilio, Benedetto Bruno, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 598.
DOI: https://doi.org/10.1182/blood-2019-126521
Published: 2019
Journal Articles

FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and Tolerance

Devi Gunasekera, MBBS, Pooja Vir, PhD, Ahmad Faisal Karim, PhD, Margaret V. Ragni, MD MPH, Elizabeth P. Merricks, PhD, Timothy C. Nichols, MD, Kathleen P. Pratt, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 630.
DOI: https://doi.org/10.1182/blood-2019-124880
Published: 2019
Journal Articles

The Unfolded Protein Response Causes Prothrombotic Transformation of Pancreatic Cancer Linking Tumor Progression with Cancer-Associated Thrombosis

Oluwatoyosi Muse, PhD, Rushad Patell, MD, Christian Peters, PhD, Sol Schulman, MD PhD, Emale Darzi, MS, Calvin Schuster, BA, Ling Huang, PhD, Shibani Mukherjee, PhD, Senthil Muthuswamy, PhD, Jeffrey I. Zwicker, MD, Robert C. Flaumenhaft, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 632.
DOI: https://doi.org/10.1182/blood-2019-123544
Published: 2019
Journal Articles

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Tomasz Brzoska, PhD, Margaret F. Bennewitz, PhD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Matthew D Neal, MD, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 976.
DOI: https://doi.org/10.1182/blood-2019-130592
Published: 2019
Journal Articles

Increased Expression of Type 1 Interferon Stimulated Genes in Sickle Cell Disease and a Potential Association with RBC Alloimmunization

Emaan Madany, BS, Najwa El Kadi, PhD, Sumaarg Pandya, Jeanne E. Hendrickson, MD, David R Gibb, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 716.
DOI: https://doi.org/10.1182/blood-2019-124899
Published: 2019
Journal Articles

Application of RNA Sequencing Detects a Large Number of Novel Fusion Transcripts in Patients with AML and MDS

Anna Stengel, PhD, Rabia Shahswar, MD, Wencke Walter, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 887.
DOI: https://doi.org/10.1182/blood-2019-124310
Published: 2019