Search Results | Blood | American Society of Hematology

1-20 of 46

2 3

Sort by

Sort Order Select

Journal Articles

A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients

Kirsten Canté-Barrett, PhD, Laurent Holtzer, PhD, Henk van Ooijen, PhD, Rico Hagelaar, Valentina Cordo', MSc, Wim Verhaegh, PhD, Anja van de Stolpe, MD PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 4661.

DOI: https://doi.org/10.1182/blood-2019-122856

Published: 2019

Journal Articles

FBXW7 is a biologically validated cancer driver gene for CLL

Davide Rossi

Blood (2019) 133 (8): 774–776.

DOI: https://doi.org/10.1182/blood-2018-12-891507

Published: 2019

Journal Articles

FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL

Viola Close, William Close, Sabrina Julia Kugler, Michaela Reichenzeller, Deyan Yordanov Yosifov, Johannes Bloehdorn, Leiling Pan, Eugen Tausch, Mike-Andrew Westhoff, Hartmut Döhner, Stephan Stilgenbauer, Franz Oswald, Daniel Mertens

Blood (2019) 133 (8): 830–839.

DOI: https://doi.org/10.1182/blood-2018-09-874529

Published: 2019

Includes: Supplemental data

Journal Articles

FBXW7 Is Critical for B1 Cell Maintenance and Function

Parham Ramezani-Rad, PhD, Charlotte R Leung, MS, John R Apgar, PhD, Robert C Rickert, PhD

Blood (2018) 132 (Supplement 1): 2565.

DOI: https://doi.org/10.1182/blood-2018-99-120387

Published: 2018

Journal Articles

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Sarah Pagliaro, Pharm D, Christophe Desterke, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 934.

DOI: https://doi.org/10.1182/blood-2018-99-110679

Published: 2018

Journal Articles

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

Blood (2018) 132 (Supplement 1): 917.

DOI: https://doi.org/10.1182/blood-2018-99-119144

Published: 2018

Journal Articles

NOTCH1 Signaling Is Activated in CLL By Mutations of FBXW7 and Low Expression of USP28 at 11q23

Viola Close, MSc, William Close, MSc, Sabrina Julia Kugler, PhD, Michaela Reichenzeller, PhD, Deyan Yordanov Yosifov, PhD, Johannes Bloehdorn, MD, Leiling Pan, MSc, Eugen Tausch, MD, Mike-Andrew Westhoff, PhD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD PhD, Franz Oswald, PhD, Daniel Mertens

Blood (2018) 132 (Supplement 1): 946.

DOI: https://doi.org/10.1182/blood-2018-99-114491

Published: 2018

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

Clonal Evolution of Molecular and Cytogenetic Aberrations in 80 CLL Patients

Sabine Jeromin, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2017) 130 (Supplement 1): 1720.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1720.1720

Published: 2017

Journal Articles

RPS15 mutations and Treatment Outcome in Chronic Lymphocytic Leukemia - Results from the CLL11 Phase III Trial (Chlorambucil (Clb) with or without the Addition of Rituximab (R) or Obinutuzumab (GA101, G)) of the German CLL Study Group

Sven Estenfelder, MD, Ann-Kathrin Holland-Letz, Eugen Tausch, MD, Sandra Robrecht, PhD, Jasmin Bahlo, PhD, Valentin Goede, MD, Veronika Opatrna, MD, Matthias Ritgen, Jacques JM van Dongen, Anton W Langerak, Günter Fingerle-Rowson, MD PhD, Michael Kneba, MD, Kirsten Fischer, MD, Michael Hallek, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD PhD

Blood (2017) 130 (Supplement 1): 1738.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1738.1738

Published: 2017

Journal Articles

Impact of Infrequently Mutated Genes on Prognosis in 531 Untreated CLL Patients

Sabine Jeromin, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Torsten Haferlach, MD, Wolfgang Kern, MD

Blood (2017) 130 (Supplement 1): 3005.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3005.3005

Published: 2017

Journal Articles

Clonal Evolution in CLL

Simon Bouzy, Marine Armand, Clementine Gabillaud, Elise Chapiro, Nadia Bougacha, Fotini Kostopoulou, PhD, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, Karim Maloum, Veronique Leblond, Veronique Morel, Damien Roos-Weil, Anne Lavaud, Jean Gabarre, Choquet Sylvain, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD

Blood (2017) 130 (Supplement 1): 3008.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3008.3008

Published: 2017

Journal Articles

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

Blood (2017) 130 (Supplement 1): 4304.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.4304.4304

Published: 2017

Journal Articles

TAL1 Super Enhancer Aberration and Stil-TAL1 Fusion in Pediatric T Cell Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): 1734.

DOI: https://doi.org/10.1182/blood.V128.22.1734.1734

Published: 2016

Journal Articles

Oncogenetic Risk Classification Based on NOTCH1/FBXW7/RAS/PTEN Mutation Profiles Improves Outcome Prediction in Pediatric T-Cell Acute Lymphoblastic Leukemia, Treated According the Fralle 2000 T Guidelines

Arnaud Petit, MD PhD, Amélie Trinquand, MD, Sylvie Chevret, MD PhD, Paola Fabiola Ballerini, MD PhD, Jean-Michel Cayuela, MD, Nathalie Grardel, MD, Aurore Touzart, MD, Benoit Brethon, MD, Hélène Lapillonne, MD PhD, Pascal Chastagner, MD, Claire Berger, MD, Gerard Michel, MD, Claude Preudhomme, MD PhD, Jean Soulier, MD PhD, Judith Landman-Parker, MD, Guy Leverger, MD, Elizabeth Macintyre, MD PhD, Andre Baruchel, MD PhD, Vahid Asnafi, MD PhD

Blood (2016) 128 (22): 1083.

DOI: https://doi.org/10.1182/blood.V128.22.1083.1083

Published: 2016

Journal Articles

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

Keyur P. Patel, MD PhD, Rajesh Singh, PhD, Mark Routbort, MD PhD, C. Cameron Yin, MD PhD, Rashmi Kanagal Shamanna, PhD, Nitin Jain, MD, Xinyan Lu, MD, Sherry Pierce, BSN, BA, Michael Keating, MBBS, Hagop M. Kantarjian, MD, L. Jeffrey Medeiros, MD, Raja Luthra, PhD, William G. Wierda, MD PhD

Blood (2016) 128 (22): 3196.

DOI: https://doi.org/10.1182/blood.V128.22.3196.3196

Published: 2016

Journal Articles

Targeted Sequencing for Clinical Investigation in Chronic Lymphocytic Leukemia

Damien Roos-Weil, Jérôme Lambert, MD PhD, Nathalie M. Droin, PhD, Frederik Damm, MD PhD, Romain Guieze, MD PhD, M'boypa Diop, Pierre Feugier, MD PhD, Stéphane Leprêtre, MD, Xavier Troussard, MD PhD, Vincent Ribrag, MD, Sandrine Vaudaux, Roselyne Delepine, Sophie Raynaud, MD, Julie Lejeune, Claude Lesty, Olivier A. Bernard, PhD, Florence Nguyen-Khac, MD PhD

Blood (2016) 128 (22): 3202.

DOI: https://doi.org/10.1182/blood.V128.22.3202.3202

Published: 2016

Journal Articles

Characterization of MDS Harboring TET2 Mutations and/or TET2 Deletions

Claudia Haferlach, MD, Anna Stengel, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2016) 128 (22): 4288.

DOI: https://doi.org/10.1182/blood.V128.22.4288.4288

Published: 2016

Journal Articles

The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia

Blood (2015) 126 (23): 691.

DOI: https://doi.org/10.1182/blood.V126.23.691.691

Published: 2015

Journal Articles

A Quantitative Analysis of Subclonal and Clonal Gene Mutations Occurring Pre- and Post-Therapy in 53 Cases of Chronic Lymphocytic Leukemia

Nisar A. Amin, Erlene Kuizon Seymour, Peter Ulintz, Kamlai Saiya-Cork, Brian Parkin, Kerby Shedden, Sami N. Malek

Blood (2015) 126 (23): 2909.

DOI: https://doi.org/10.1182/blood.V126.23.2909.2909

Published: 2015

2 3

NARROW

A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients

FBXW7 is a biologically validated cancer driver gene for CLL

FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL

FBXW7 Is Critical for B1 Cell Maintenance and Function

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Mutational Landscape and Temporal Evolution during Treatment of Relapsed Acute Lymphoblastic Leukemia

NOTCH1 Signaling Is Activated in CLL By Mutations of FBXW7 and Low Expression of USP28 at 11q23

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Clonal Evolution of Molecular and Cytogenetic Aberrations in 80 CLL Patients

RPS15 mutations and Treatment Outcome in Chronic Lymphocytic Leukemia - Results from the CLL11 Phase III Trial (Chlorambucil (Clb) with or without the Addition of Rituximab (R) or Obinutuzumab (GA101, G)) of the German CLL Study Group

Impact of Infrequently Mutated Genes on Prognosis in 531 Untreated CLL Patients

Clonal Evolution in CLL

Standardized Targeted Sequencing of 29 Genes with Recurrent Mutations in Chronic Lymphocytic Leukemia (CLL) Helps to Better Define Clinical Correlates and Genomic Hotspots

TAL1 Super Enhancer Aberration and Stil-TAL1 Fusion in Pediatric T Cell Acute Lymphoblastic Leukemia

Oncogenetic Risk Classification Based on NOTCH1/FBXW7/RAS/PTEN Mutation Profiles Improves Outcome Prediction in Pediatric T-Cell Acute Lymphoblastic Leukemia, Treated According the Fralle 2000 T Guidelines

Routine Clinical Testing for Actionable Mutations in CLL Using Endcll Assay V1: The Initial MD Anderson Experience

Targeted Sequencing for Clinical Investigation in Chronic Lymphocytic Leukemia

Characterization of MDS Harboring TET2 Mutations and/or TET2 Deletions

The Genomic Landscape of Childhood T-Lineage Acute Lymphoblastic Leukemia

A Quantitative Analysis of Subclonal and Clonal Gene Mutations Occurring Pre- and Post-Therapy in 53 Cases of Chronic Lymphocytic Leukemia

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only