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Journal Articles

Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia

Lili Song, Bo Yu, Yi Yang, Jianwei Liang, Yingwen Zhang, Lixia Ding, Tianyi Wang, Xinyu Wan, Xiaomin Yang, Jingyan Tang, Shengyue Wang, Benshang Li, Yanxin Li, Haizhong Feng
Journal: Blood
Blood (2021) 137 (9): 1181–1191.
https://doi.org/10.1182/blood.2020005622
Published: 2021
Includes: Supplemental data
Journal Articles

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Daniel Sasca, Haiyang Yun, George Giotopoulos, Jakub Szybinski, Theo Evan, Nicola K. Wilson, Moritz Gerstung, Paolo Gallipoli, Anthony R. Green, Robert Hills, Nigel Russell, Cameron S. Osborne, Elli Papaemmanuil, Berthold Göttgens, Peter Campbell, Brian J. P. Huntly
Journal: Blood
Blood (2019) 134 (24): 2195–2208.
https://doi.org/10.1182/blood.2019001553
Published: 2019
Includes: Supplemental data
Journal Articles

High Risk Genomic Alterations Identified at the Time of Diagnosis Are Strongly Associated with MRD and Subsequent Poor Outcomes in AYA ALL Patients Treated on a Pediatric Inspired Chemotherapy Regimen

David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Matthew Greenwood, MBBS, FRACP, FRCPA, Jacqueline Rhen, BSc MSc MD, Susan L Heatley, PhD MD, Barbara McClure, BSc (Hons) PhD, Laura N Eadie, BSc (Hons) PhD, Jimmy Breen, BSc (Hons) PhD, Caitlin Schutz Schutz, BSc (Hons), Toby N Trahair, MBBS FRACP PhD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Luciano Dalla-Pozza, MBBS FRACP, Rosemary Sutton, BSc MSc PhD, Kenneth F Bradstock, BSc(MD, MBBS, PhD FRACP, FRCPA, Michael Philip Osborn, MB, BS, Deborah L. White, PhD FFSc (RCPA)
Journal: Blood
Blood (2019) 134 (Supplement_1): 3949.
https://doi.org/10.1182/blood-2019-127788
Published: 2019
Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2316.
https://doi.org/10.1182/blood-2019-132032
Published: 2019
Journal Articles

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Marlie H Fisher, Leila J. Noetzli, PhD, Michael Callaghan, MD, Walter H. Kahr, MDPhDFRCPC, Jesse W Rowley, PhD, Jorge Di Paola, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2468.
https://doi.org/10.1182/blood-2019-131967
Published: 2019
Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2754.
https://doi.org/10.1182/blood-2019-128835
Published: 2019
Journal Articles

Whole Genome Profiling of Adult B-Other Acute Lymphoblastic Leukaemia on the UKALL14 Trial

Daniel A. Leongamornlert, PhD, Emilio Barretta, Soo Lee, Thomas Creasey, MBBS, Rachel J. Mitchell, MSc, Amy A. Kirkwood, MSc, Laura Clifton-Hadley, PhDBSc, Pip Patrick, PhDMSc,MA, Peter J Campbell, Bela Wrench, MBBS, MD MRCP, FRCPath, Anthony V. Moorman, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Elli Papaemmanuil, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2743.
https://doi.org/10.1182/blood-2019-125723
Published: 2019
Journal Articles

Role of IGF2BP1 and Target Genes in ETV6-RUNX1 Positive B-Acute Lymphoblastic Leukemia

Jayanth Kumar Palanichamy, MD, Gunjan Sharma, MSc, Thakur Nidhi, MBBS, Anita Chopra, MD DM, Sameer Bakhshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3818.
https://doi.org/10.1182/blood-2019-128019
Published: 2019
Journal Articles

In-Depth Proteomic Characterization of Lineage-Biased Hematopoietic Progenitor Cells in the Fetus and Adult

Maria Jassinskaja, MSc, Kristýna Pimková, PhD, Emil Johansson, MSc, Ewa Sitnicka Quinn, PhD, Jenny Hansson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3703.
https://doi.org/10.1182/blood-2019-121799
Published: 2019
Journal Articles

Cytogenetic Characteristics and Outcomes of Patients Receiving CTL019 CAR T Cell Therapy

Allison Barz Leahy, MD, Kaitlin J. Stanley, MD, Regina M. Myers, MD, Amanda M. DiNofia, MD, Lisa Wray, MD, Susan R. Rheingold, MD, Colleen Callahan, CRNP, Diane Baniewicz, CRNP, Amy E. Barry, PPCNP-BC, Maria M. Patino, BS, Stephen P. Hunger, MD, Stephan Grupp, MD PhD, David M. Barrett, Shannon L. Maude, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1464.
https://doi.org/10.1182/blood-2019-130060
Published: 2019
Journal Articles

Features of an Unusual AML with t(4;12)/ Pdgra-ETV6 As the Sole Cytogenetic Abnormality Associated with Myelodysplastic Changes: A Case Report and Literature Review

Jitakshi De, MD, L. Jeffrey Medeiros, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5162.
https://doi.org/10.1182/blood-2019-129035
Published: 2019
Journal Articles

Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14

Anthony V. Moorman, Ellie Butler, Emilio Barretta, Amy A. Kirkwood, MSc, Claire Schwab, PhD, Thomas Creasey, MBBS, Daniel A. Leongamornlert, PhD, Elli Papaemmanuil, PhD, Pip Patrick, PhDMSc,MA, Laura Clifton-Hadley, PhDBSc, Bela Wrench, MBBS, MD MRCP, FRCPath, Tobias F Menne, MD PhD FRCPath, Andrew K McMillan, FRCP, Christine J. Harrison, PhD FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David I Marks, MBBS, PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 288.
https://doi.org/10.1182/blood-2019-123642
Published: 2019
Journal Articles

Core Transcriptional Regulatory Circuitries in AML

Maxim Pimkin, MD PhD, Juliana Xavier Ferrucio, PhD, Neekesh Vijay Dharia, MD PhD, Taku Harada, Andrew Kossenkov, Selma Elsarrag, Jazmin Ewers, Charles Y Lin, PhD, Kimberly Stegmaier, MD, Stuart H. Orkin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 280.
https://doi.org/10.1182/blood-2019-129297
Published: 2019
Journal Articles

Genetic defects in hematopoietic transcription factors and predisposition to acute lymphoblastic leukemia

Yoshihiro Gocho, Jun J. Yang
Journal: Blood
Blood (2019) 134 (10): 793–797.
https://doi.org/10.1182/blood.2018852400
Published: 2019
Journal Articles

ETV6-related thrombocytopenia and leukemia predisposition

Jorge Di Paola, Christopher C. Porter
Journal: Blood
Blood (2019) 134 (8): 663–667.
https://doi.org/10.1182/blood.2019852418
Published: 2019
Includes: Supplemental data
Journal Articles

Yet another susceptibility variant for ALL: what’s next?

Kjeld Schmiegelow
Journal: Blood
Blood (2019) 133 (7): 628–629.
https://doi.org/10.1182/blood-2018-12-891564
Published: 2019
Journal Articles

Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics

Brief Report
Maoxiang Qian, Heng Xu, Virginia Perez-Andreu, Kathryn G. Roberts, Hui Zhang, Wenjian Yang, Shouyue Zhang, Xujie Zhao, Colton Smith, Meenakshi Devidas, Julie M. Gastier-Foster, Elizabeth Raetz, Eric Larsen, Esteban G. Burchard, Naomi Winick, W. Paul Bowman, Paul L. Martin, Michael Borowitz, Brent Wood, Federico Antillon-Klussmann, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Stephen P. Hunger, Mary V. Relling, Mignon L. Loh, Jun J. Yang
Journal: Blood
Blood (2019) 133 (7): 724–729.
https://doi.org/10.1182/blood-2018-07-862946
Published: 2019
Includes: Supplemental data
Journal Articles

Gene Aberrations in Adult Patients with Ph-Negative ALL in the Czech Republic

Zuzana Vrzalova, PhD, Hana Jelinkova, Stepan Hrabovsky, Frantisek Folber, MD PhD, Cyril Salek, Jan Horacek, Marketa Zaliova, Jiri Stika, Martina Slavikova, Sarka Pospisilova, Michael Doubek, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4090.
https://doi.org/10.1182/blood-2018-99-118308
Published: 2018
Journal Articles

High Frequency of the Ph-like PCB-ALL Subtype in Mexican Pediatric Patients. Experience in Two Institutions

Patricia Perez-Vera, PhD, Dafne Moreno Lorenzana, PhD, María Del Rocío Juárez-Velázquez, PhD, Daniel Alejandro Martínez-Anaya, BSc, Adriana Reyes-León, PhD, Adrián Hernández-Monterde, BSc, Maria Montserrat Aguilar, PhD, Oscar Soto Lerma, MD, Martha Herrera-Almanza, MD, Marta Zapata-Tarres, PhD, Luis Juarez-Villegas, MD, Rocio Cardenas-Cardos, MD, Roberto Rivera-Luna, MD, Alberto Olaya-Vargas, MD M.Sc
Journal: Blood
Blood (2018) 132 (Supplement 1): 4092.
https://doi.org/10.1182/blood-2018-99-119541
Published: 2018
Journal Articles

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1 + Preleukemic Cells Persistence and DNA Damaging

Linda Beneforti, Erica Dander, PhD, Silvia Bresolin, PhD, Clara Bueno, Geertruy te Kronnie, Anthony Ford, Pablo Menendez, Giovanna D'Amico, BSc, PhD MSc, Andrea Biondi, Chiara Palmi, Giovanni Cazzaniga, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3918.
https://doi.org/10.1182/blood-2018-99-114791
Published: 2018