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Journal Articles

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Alexandre Slater, Ying Di, Joanne C. Clark, Natalie J. Jooss, Eleyna M. Martin, Fawaz Alenazy, Mark R. Thomas, Robert A. S. Ariëns, Andrew B. Herr, Natalie S. Poulter, Jonas Emsley, Steve P. Watson
Journal: Blood
Blood (2021) 137 (24): 3443–3453.
https://doi.org/10.1182/blood.2020009440
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Taking aim at IDH in fitter patients with AML

Andrew H. Wei, Naval Daver
Journal: Blood
Blood (2021) 137 (13): 1706–1707.
https://doi.org/10.1182/blood.2020009361
Published: 2021
Journal Articles

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study

Clinical Trials & Observations
Eytan M. Stein, Courtney D. DiNardo, Amir T. Fathi, Alice S. Mims, Keith W. Pratz, Michael R. Savona, Anthony S. Stein, Richard M. Stone, Eric S. Winer, Christopher S. Seet, Hartmut Döhner, Daniel A. Pollyea, James K. McCloskey, Olatoyosi Odenike, Bob Löwenberg, Gert J. Ossenkoppele, Prapti A. Patel, Mikhail Roshal, Mark G. Frattini, Frederik Lersch, Aleksandra Franovic, Salah Nabhan, Bin Fan, Sung Choe, Hongfang Wang, Bin Wu, Lei Hua, Caroline Almon, Michael Cooper, Hagop M. Kantarjian, Martin S. Tallman
Journal: Blood
Blood (2021) 137 (13): 1792–1803.
https://doi.org/10.1182/blood.2020007233
Published: 2021
Includes: Supplemental data
Journal Articles

V2 Trial: A Phase I Study of Venetoclax Combined with CPX-351 for Children, Adolescents and Young Adults with Relapsed or Refractory Acute Leukemia

Laura Agresta, MD, Maureen M O'Brien, MD, Kana Mizuno, PhD, Robin Norris, MD MS, MPH, Erin H. Breese, MD PhD, Christine L Phillips, MD, Karen Burns, MD, Benjamin Mizukawa, Lynn Lee, MD, Adam Lane, PhD, Robert B. Lorsbach, MD PhD, Thomas D. Ryan, MD PhD, Pankaj B. Desai, PhD, Alexander A. Vinks, PharmD, PhD, H. Leighton Grimes, PhD, John P Perentesis, Michael J. Absalon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3830.
https://doi.org/10.1182/blood-2019-121514
Published: 2019
Journal Articles

Sequential Combination of Inotuzumab Ozogamicin (InO) with Low-Intensity Chemotherapy (Mini-hyper-CVD) with or without Blinatumomab Is Highly Effective in Patients (pts) with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL) in First Relapse

Koji Sasaki, MD, Hagop M. Kantarjian, MD, Farhad Ravandi, MD, Nicholas J. Short, MD, Partow Kebriaei, MD, Xuelin Huang, PhD, Michael E. Rytting, MD, Nitin Jain, MD, Marina Y Konopleva, MD PhD, Guillermo Garcia-Manero, MD, Richard E. Champlin, MD, Tapan M. Kadia, MD, Jorge E. Cortes, MD, Zeev E. Estrov, MD, Koichi Takahashi, MD, Christopher Loiselle, BS, Corabelle Encarnacion, RDC, Meagan Rostykus, RN, Rita Khouri, Patrice Nasnas, MD, Jovitta Jacob, RN, Monica Kwari, BSN, Rebecca Garris, MSc, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3806.
https://doi.org/10.1182/blood-2019-129018
Published: 2019
Journal Articles

An Oral Combination Study of Novel Nucleoside Analogue Sapacitabine and BCL2 Inhibitor Venetoclax to Treat Patients with Relapsed or Refractory AML or MDS

Tapan M. Kadia, MD, Gautam M. Borthakur, MD, Elias Jabbour, MD, Marina Y Konopleva, MD PhD, Farhad Ravandi, MD, Courtney D. DiNardo, MDMSc, Daniella Zheleva, PhD, David Blake, PhD, Judy H Chiao, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3926.
https://doi.org/10.1182/blood-2019-131930
Published: 2019
Journal Articles

A New Molecular Variant in the PTGS1 Gene That Abrogates Generation of Thromboxane A2 Synthesis and Associates with Platelet Dysfunction and Bleeding

Veronica Palma-Barqueros, MSc, Melissa Chan, PhD, Marilena Crescente, PhD, Jose Maria Bastida, Elena Almarza, PhD, Sara Suarez Varela, MD, Cristina Mesa-Núñez, PhD, Ignacio Casas-Avilés, MD, Natalia Bohdan, Jf Ruiz-Pividal, MSc, Jose Padilla, Nuria Revilla Calvo, MD, A Marín-Quilez, MSc, Marta Martín Izquierdo, MSc, Rocio Benito, PhD, Vicente Vicente, MD PhD, Juan A. Bueren, PhD, Jesus Maria . Hernández-Rivas, MD, José Ramón González-Porras, MD PhD, ML Edin, PhD, DC Zelding, MD, Tim Warner, PhD, Jose Rivera, PhD, Maria Luisa Lozano, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2375.
https://doi.org/10.1182/blood-2019-129200
Published: 2019
Journal Articles

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Moua Yang, PhD, Calvin Harberg, Wenjing Chen, Sarah L. Wynia-Smith, PhD, Kate S. Carroll, PhD, Jacek Zielonka, PhD, Roy L. Silverstein, MD, Brian C. Smith, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2338.
https://doi.org/10.1182/blood-2019-122465
Published: 2019
Journal Articles

Biomarkers of Hemostatic Activation and Inflammation Are Associated with Altered Coagulation Parameters in Sepsis Patients

Emily Bontekoe, Matthew T. Rondina, MD, Debra Hoppensteadt, PhD, Elizabeth Middleton, MD, Antoinette Blair, Fakiha Siddiqui, Divya Joshi, Alyssandra Abrenica, Iman Darwish, Maryanne Amour, Jawed Fareed, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2401.
https://doi.org/10.1182/blood-2019-130420
Published: 2019
Journal Articles

Decreased Thrombin Generation Potential in Lymphoma Patients Is Associated with Increased D-Dimer, CRP, Vwf and TNF-α. Interrelationship between Thrombogenesis and Inflammation

Fakiha Siddiqui, Emily Bontekoe, Darko Antic, PhD, Debra Hoppensteadt, PhD, Grigoris Gerotziafas, MD PhD, Jawed Fareed, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5239.
https://doi.org/10.1182/blood-2019-128440
Published: 2019
Journal Articles

Primary Bone Non-Hodgkin's Lymphoma: A Specific Clinical Entity with Aggressive Clinical Course and High Cure Rate - Retrospective Analysis of 102 Patients from Greece

Argiris Symeonidis, MD PhD, Sotirios Papageorgiou, MD PhD, Antonis Patrinos, MD, Maria Melachrinou, MD PhD, Alexandra Kourakli, MD PhD, Vassiliki Pappa, MD, Maria K. Angelopoulou, MD, Anastasia Sioni, Nikolaos Kanellias, MD, Sofia Chatzileontiadou, MD, Eleftheria Hatzimichael, Panagiotis Zikos, Anastasia Pouli, MD PhD, Maria Papaioannou, Evangelos Terpos, MD PhD, Gerasimos Pangalis, MD, Theodoros P. Vassilakopoulos, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5340.
https://doi.org/10.1182/blood-2019-130219
Published: 2019
Journal Articles

Cytokine Release Syndrome As a Rare Complication of Nivolumab: A Case Report

Alexander Slota, MD, Roomana Khan, MD, Akhil Rahman, MD, Eiran A Warner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5630.
https://doi.org/10.1182/blood-2019-127586
Published: 2019
Journal Articles

Progression Free Survival (PFS), and Event Free Survival (EFS) from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 815 Patients with Treatment Naïve (TN) AML Unfit for Intensive Chemotherapy (IC): ASTRAL-1 Study

Jean-Pierre Issa, MD, Marco Gobbi, MD, Patricia L. Kropf, MD, Pierre Fenaux, MD PhD, Gail J. Roboz, MD, Jiri Mayer, MD, Jürgen Krauter, MD, Tadeusz Robak, MD, Hagop M. Kantarjian, MD, Jan Novak, MD PhD, Wieslaw W. Jedrzejczak, MD PhD, Xavier Thomas, MD PhD, Mario Ojeda-Uribe, MD, Yasushi Miyazaki, MD PhD, Yoo Hong Min, MD PhD, Su-Peng Yeh, MD, Joseph M Brandwein, MD, Liana Gercheva, MD, Judit Demeter, MD, Elizabeth A. Griffiths, MD, Karen W.L. Yee, MD, Yong Hao, MD PhD, Mohammad Azab, MD, Hartmut Döhner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4235.
https://doi.org/10.1182/blood-2019-129614
Published: 2019
Journal Articles

High Serum VEGF Level in Erdheim-Chester Disease: Correlation with Cardiovascular Involvement and Response to Treatment

Anaïs Roeser, MD, Marine Bravetti, MD, Levi-Dan Azoulay, MD, Makoto Miyara, MD, Jean-François Emile, MD, Jean Donadieu, MD PhD, Zahir Amoura, MD MSc, Fleur Cohen-Aubart, MD PhD, Julien Haroche
Journal: Blood
Blood (2019) 134 (Supplement_1): 2324.
https://doi.org/10.1182/blood-2019-129984
Published: 2019
Journal Articles

Lintuzumab Ac-225 in Combination with CLAG-M Chemotherapy in Relapsed/Refractory AML: Interim Results of a Phase I Study

Sameem Abedin, MD, Guru Subramanian Guru Murthy, MBBS, Lyndsey Runaas, MD, Laura C. Michaelis, MD, Ehab L. Atallah, MD, Mehdi Hamadani, MD, Alexandra M. Harrington, MDMT(ASCP), Karen Carlson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2605.
https://doi.org/10.1182/blood-2019-122487
Published: 2019
Journal Articles

Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 815 Patients with Treatment Naïve (TN) AML Unfit for Intensive Chemotherapy (IC) ASTRAL-1 Study: Analysis By Number of Cycles

Gail J. Roboz, MD, Hartmut Döhner, MD, Marco Gobbi, MD, Patricia L. Kropf, MD, Jiri Mayer, MD, Jürgen Krauter, MD, Tadeusz Robak, MD, Hagop M. Kantarjian, MD, Jan Novak, MD PhD, Wieslaw Jedrzejczak, MD, Xavier Thomas, MD PhD, Mario Ojeda-Uribe, MD, Yasushi Miyazaki, MD PhD, Yoo Hong Min, MD PhD, Su-Peng Yeh, MD, Joseph M Brandwein, MD, Liana Gercheva, MD, Judit Demeter, MD, Elizabeth A. Griffiths, MD, Karen W.L. Yee, MD, Jean-Pierre Issa, MD, Yong Hao, MD PhD, Mohammad Azab, MD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2591.
https://doi.org/10.1182/blood-2019-127253
Published: 2019
Journal Articles

Urine Proteomic Analysis Reveals Disease-Specific Patterns in Pediatric Patients with Classical Hodgkin's Disease(HD). an Addon Study to the Euronet-PHL-C2 Trial

Karl-Walter Sykora, MD, Jochen Metzger, PhD, Dieter Körholz, MD PhD, Michael Frühwald, MD, Gabriele Strauss, MD, Norbert Jorch, MD, Jozef Zlocha, MD PhD, Thomas Wiesel, MD, Axel Sauerbrey, MD, Monika Streiter, MD, Rhoikos Furtwaengler, MD, Gunnar Cario, MD PhD, Thorsten Simon, MD PhD, Holger Christiansen, MD, Peter Vorwerk, MD, Angela Wawer, MD, Wolfram Scheurlen, MD, Hermann Müller, MD, Stefan Bielack, MD, Martin Ebinger, PD Dr. MD, Klaus-Michael Debatin, MD, Oliver Andres, MD, Christine Mauz-Körholz, Anja Troeger, MD, Dominik Schneider, MD, Eva M Weissinger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2804.
https://doi.org/10.1182/blood-2019-125611
Published: 2019
Journal Articles

Venetoclax Combined with Cladribine + Low Dose AraC (LDAC) Alternating with 5-Azacytidine Produces High Rates of Minimal Residual Disease (MRD) Negative Complete Remissions (CR) in Older Patients with Newly Diagnosed Acute Myeloid Leukemia (AML)

Tapan M. Kadia, MD, Jorge E. Cortes, MD, Marina Y Konopleva, MD PhD, Gautam M. Borthakur, MD, Naveen Pemmaraju, MD, Naval G. Daver, MD, Guillermo Montalban Bravo, MD, Ghayas C. Issa, MD, Kiran Naqvi, MDMPH, Nicholas J. Short, MD, Courtney D. DiNardo, MDMSc, Kapil N. Bhalla, MD, Elias Jabbour, MD, Koichi Takahashi, MD, Koji Sasaki, MD, Steven M. Kornblau, MD, Rashmi Malla, RN, BSN, Sherry A. Pierce, BSN, BA, Xuemei Wang, MS, Zeev E. Estrov, MD, Michael Andreeff, MD PhD, Guillermo Garcia-Manero, MD, Farhad Ravandi, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2647.
https://doi.org/10.1182/blood-2019-122477
Published: 2019
Journal Articles

A Phase I Study of Single-Agent Inotuzumab Ozogamicin in Pediatric CD22-Positive Relapsed/Refractory Acute Lymphoblastic Leukemia: Preliminary Results of the ITCC-059 Study

Erica Brivio, MD, Marta Lopez-Yurda, PhD, Cormac Ownes, MD, Cristina Díaz de Heredia, MD PhD, Bella Bielorai, MD, Claudia Rossig, Vincent van der Velden, PhD, Anneke C.J. Ammerlaan, Inge M. van der Sluis, MD PhD, Monique L. Den Boer, PhD, Ying Chen, Barbara Sleight, MD, Benoit Brethon, MD, Karsten Nysom, Jan Stary, Prof., MD PhD, Ingrid Øra, Christiane Chen-Santel, Luciana Vinti, MD, Franco Locatelli, MD PhD, Christian Michel Zwaan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2629.
https://doi.org/10.1182/blood-2019-122411
Published: 2019
Journal Articles

Successful Treatment of Chimeric Antigen Receptor T Cell Therapy in Refractory or Relapsed Acute Leukemia Patients with TP53 alterations

Changju Qu, PhD, Jia Yin, Liqing Kang, Zheng Li, Haiping Dai, Xiaming Zhu, Lei Yu, Depei Wu, MD PhD, Xiaowen Tang
Journal: Blood
Blood (2019) 134 (Supplement_1): 3822.
https://doi.org/10.1182/blood-2019-128013
Published: 2019